• Korea-Australia Rheology Journal
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• 제21권4호
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• pp.289-297
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• 2009

We numerically analyzed flow characteristics of the polymer melt in the screw equipment using a proper modeling and investigated design parameters which have influence on the mixing performance as the capability of the screw equipment. We considered the non-Newtonian and non-isothermal flow in a single rotor equipment to investigate the mixing performance with respect to screw dimensions as shape parameter of the single rotor equipment and screw speed as process parameter. We used Bird-Carreau-Yasuda model as a viscous model of the polymer melt and the particle tracking method to investigate the mixing performance in the screw equipment and considered four mixing performance indexes: residence time distribution, deformation rate, total strain and particle standard deviation as a new mixing performance index. We compared these indexes to determine design parameters and object function. On basis of the analysis results, we carried out the optimal design by using the response surface method and design of experiments. In conclusion, the differences of results between the optimal value and numerical analysis are about 5.0%.

• Toxicological Research
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• 제17권1호
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• pp.59-63
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• 2001

In this study, we compared skin response between Hartley guinea pig and New Zealand white rabbit. New Zealand white rabbit was treated by a glycolic acid (0, 8, 24, 40, 56 mg/$cm^2$) and UVB (0, 0.4, 3.0 J/$cm^2$) for 14 days. Skin irritation by glycolic acid and UVB were increased in dose and time-dependent manners, and the combination treatment of UVB increased glycolic acid-induced skin irritation. Comparison the skin irritation index between guinea pig and rabbit showed that guinea pig was much more sensitive to glycolic acid and UVB. This study indicated that selection of reliable species of animal could be considered in chemical-induced skin irritation study.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1992년도 춘계학술대회 논문집
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• pp.380-384
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• 1992

The position control of a pneumatic cylinder suing low cost on-off valves is studied. The valve control band(VCB) was proposed toget fast response and toprevent solenoid valves from unnecessary switching at the beginning of response. A learning algorithm was used to compensate the nonlinearity and complexity in mathematical modelling of pheumatic on-off controlled positioning systems. In this algorithm, the desired performance index and modified learning rate, were proposed to improvespeed and convergence of learning control. It is shown experimentally that the proposed algorithm is robust to changes of system parameters: the setting time less than 1.0 sec and the error bound of .+-. 0.1 mm can be obtained. The effects of supply pressure, size of switching valves and the effect of multiple valves are discussed, and computer simulation onthe dynamic performances of the pneumatic system is also presented.

• 대한전기학회논문지
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• 제38권9호
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• pp.671-683
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• 1989

A controller of interconnected power systems is investigated using an optimal multidimensional variable structure control. The switching hyperplane of the variable structure stabilizer is obtained by minimizing a quadratic performance index in continuous-time. A special feature of the optimal multidimensional variable structure stabilizer is that, when it is operated in the so-called sliding mode, the system response becomes insensitive to changes in the plant parameters. A digital simulation is performed by a digital computer using the Advanced Continuous Simulation Language (ACSL) package, which shows that the dynamic performance of the power system in response to mechanical torque changes is improved when optimal multidimensional variable sturcture stabilizers are employed.

• 전기학회논문지
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• 제57권8호
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• pp.1447-1453
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• 2008

In this paper, we proposed to improve performance of the design of a cascade controller with the smith-predictor structure. The parameters of controller in the inner loop are determined to minimize the integral of time multiplied by the absolute value of error (ITAE) value of performance Index. The controller of outer loop and parameters of Smith-Predictor can be obtain using reduction model. The model reduction is considered that it is the transient response and the steady-state response through the use of nyquist curve. Simulation examples are given to show the better performance of the proposed method than conventional methods.

• Clinical Endoscopy
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• 제55권4호
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• pp.480-488
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• 2022

Endoscopy is vital for diagnosis, assessing treatment response, monitoring and surveillance in patients with inflammatory bowel disease (IBD). With the growing importance of mucosal healing as a treatment target, the assessment of disease activity by endoscopy has been accepted as the standard of care for IBD. There are many endoscopic activity indices for facilitating standardized reporting of the gastrointestinal mucosal appearance in IBD, and each index has its strengths and weaknesses. Although most endoscopic indices do not have a clear-cut validated definition, endoscopic remission or mucosal healing is associated with favorable outcomes, such as a decreased risk of relapse. Therefore, experts suggest utilizing endoscopic indices for monitoring disease activity and optimizing treatment to achieve remission. However, the regular monitoring of endoscopic activity is limited in practice owing to several factors, such as the complexity of the procedure, time consumption, inter-observer variability, and lack of a clear-cut, validated definition of endoscopic response or remission. Although experts have recently suggested consensus-based definitions, further studies are needed to define the values that can predict long-term outcomes.

• 한국정보과학회논문지:데이타베이스
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• 제32권4호
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• pp.405-415
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• 2005

인덱싱 기법은 무선 환경에서 클라이언트의 선별적인 청취를 지원하기 위하여 사용된다. 즉, 서버는 브로드캐스트 채널을 통해 데이타와 인덱스를 함께 전달함으로써 클라이언트의 선택적인 청취를 지원할 수 있다. 그러나 부가적인 인덱스 정보는 브로드캐스트 주기를 증가시키는 단점이 있다. 위치기반 서비스에서의 질의에 대한 응답지연은 잘못된 결과의 전달이라는 문제점을 가져올 수 있다. 본 논문에서 우리는 무선 브로드캐스트 환경에서 k-인접질의 서비스를 지원하기 위한 BBS(Broadcast Based LDIS Scheme) 기법을 제안한다. BBS 기법에서 서버는 전달하고자 하는 데이타를 위치에 기반을 두어 정렬하며 이를 인덱스 정보와 함께 클라이언트들에게 전달한다. 또한 클라이언트의 질의 처리 수행시간을 단축시키기 위하여 프리패칭과 OBC(Object Boundary Circle)기법을 새로이 제안한다. 제안 논문에 대한 성능평가는 데이타의 분포, 클라이언트의 이동 속도 그리고 서비스 영역의 크기 등 다양한 환경에서 이루어 졌다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제26권3호
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• pp.183-189
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• 2015

Objectives : The aim of this study was to investigate Korean Wechsler Intelligence profiles and specific abilities related to attention problem of children with attention-deficit hyperactivity disorder (ADHD). Methods : The Korean Wechsler Intelligence Scale for Children-fourth edition (K-WISC-IV) and Advanced Test of Attention (ATA) were administered to 91 children and adolescents (age $8.5{\pm}2.6$ years, 73 boys) with ADHD. Pearson correlation and independent t-tests were used. Results : The means of Working Memory Index (WMI) and Processing Speed Index (PSI) showed a score of low average in K-WISC-IV. WMI scores for the K-WISC-IV showed clinically significant correlations with omission errors, commission errors, and response time variability on auditory ATA. PSI scores also showed significant correlations with response time and variability on visual ATA. In addition, significantly lower digit span backward scores were observed in hyperactive-impulsive/combined subtypes compared to inattentive subtype (t=3.60, p<.001). Conclusion : Children with ADHD showed significantly lower scores in WMI and PSI which were clinically correlated with ATA scores, and hyperactive-impulsive/combined subtypes showed poorer working memory functions in WMI. Follow-up studies are proposed.

• 한국지반공학회논문집
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• 제37권5호
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• pp.33-46
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• 2021

2016년 발생한 국내 계기 계측 사상 최대 규모의 경주지진과 2017년 팔레트구조 건축물의 기둥이 파괴되는 등 국내 최대 지진피해가 발생한 포항지진 이후, 국내 모든 시설물에 대한 내진설계기준이 개정되고 있으며 특히, 포항지진 피해사례 조사 도중 미국, 일본, 뉴질랜드 등 주로 강진지역 국가에서 발생하는 액상화 피해가 발견되어 이에 대한 설계기준의 보완도 심도있게 진행되고 있다. 이 연구에서는 최근 개정된 항만 및 어항시설 내진설계기준에서의 액상화 평가방법을 고찰하고 액상화 평가절차에 새롭게 인용된 액상화 가능성 지수(LPI)를 중심으로 적용성 검토를 수행하였다. 이때, 액상화 발생가능한 모래지반을 다양하게 조성하고 이에 대한 케이스별 LPI 값을 산정 비교하였다. 또한, 실제 22개소 항만의 지반자료를 이용하여 지진시 지반응답해석에 기초한 액상화 평가의 수행과 함께 22개소의 LPI 값들을 비교 검토하였다.

• Clinical and Experimental Reproductive Medicine
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• 제48권2호
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• pp.163-173
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• 2021

Objective: This study aimed to characterize a validated model for predicting oocyte retrieval in controlled ovarian stimulation (COS) and to construct model-based nomograms for assistance in clinical decision-making regarding the gonadotropin protocol and dose. Methods: This observational, retrospective, cohort study included 636 women with primary unexplained infertility and a normal menstrual cycle who were attempting assisted reproductive therapy for the first time. The enrolled women were split into an index group (n=497) for model building and a validation group (n=139). The primary outcome was absolute oocyte count. The dose-response relationship was tested using modified Poisson, negative binomial, hybrid Poisson-E_max, and linear models. The validation group was similarly analyzed, and its results were compared to that of the index group. Results: The Poisson model with the log-link function demonstrated superior predictive performance and precision (Akaike information criterion, 2,704; λ=8.27; relative standard error (λ)=2.02%). The covariate analysis included women's age (p<0.001), antral follicle count (p<0.001), basal follicle-stimulating hormone level (p<0.001), gonadotropin dose (p=0.042), and protocol type (p=0.002 and p<0.001 for short and antagonist protocols, respectively). The estimates from 500 bootstrap samples were close to those of the original model. The validation group showed model assessment metrics comparable to the index model. Based on the fitted model, a static nomogram was built to improve visualization. In addition, a dynamic electronic tool was created for convenience of use. Conclusion: Based on our validated model, nomograms were constructed to help clinicians individualize the stimulation protocol and gonadotropin doses in COS cycles.