• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3695-3700
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• 2012

Mammalian mediator (MED) is a multi-protein coactivator that has been identified by several research goups. The involvement of the MED complex subunit 19 (MED 19) in the metastasis of lung adenocarcinoma cell line (H1299), which expresses the MED 19 subunit, was here investigated. When MED 19 expression was decreased by RNA interference H1299 cells demonstrated reduced clone formation, arrest in the S phase of the cell cycle, and lowered metastatic capacity. Thus, MED 19 appears to play important roles in the biological behavior of non-small cell lung carcinoma cells. These findings may be important for the development of novel lung carcinoma treatments.

• Tuberculosis and Respiratory Diseases
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• v.84 no.3
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• pp.176-181
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• 2021

At the beginning of February 2020, Daegu faced a serious situation due to the rapid outbreak of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2. The healthcare system in Daegu Metropolitan City was ill-prepared for this sudden disaster situation. The COVID-19 pandemic is still ongoing in South Korea. Daegu has limited medical resources compared to the Seoul Metropolitan Area, and it is hypothesized that a review of the outbreak therein could provide information that will be valuable for dealing with future outbreaks. The likelihood of death due to COVID-19 depends on the capacity of the area for the treatment of critically ill patients. This report reviews the overall treatment process followed for critically ill patients in Daegu.

• The Journal of Internal Korean Medicine
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• v.42 no.3
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• pp.375-384
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• 2021

Objective: This study was designed to analyze the clinical features of idiopathic pulmonary fibrosis patients who attended a Korean medicine hospital and the treatment effects through retrospective chart reviews. Methods: The medical records of 82 outpatients who had been diagnosed with idiopathic pulmonary fibrosis and visited the Allergy, Immune, and Respiratory System Department of Kyung Hee Korean Medicine Hospital from 8 January 2015 to 8 January 2021 were retrospectively reviewed. To assess the treatment outcomes, we used the FVC (Forced Vital Capacity), DLCO (Diffusing capacity of the Lung for CO), 6-minute walk test, and HRCT (High Resolution Computed Tomography). Results: The study group consisted of 28 females and 54 males. The median age of the patients was 67.98±11.44 years. The chief complaints were cough (n=51) and dyspnea (n=49). Other frequent symptoms were general weakness (n=8), weight loss (n=4), and a fever (n=2). A total of 77 (93.90%) patients were prescribed Korean herbal medicine, and 52 (63.41%) patients were treated with acupuncture, moxibustion, cupping therapy, ICT, or pharmacopuncture. After treatments, FVC, DLCO, the 6-minute walk test, and HRCT were maintained or worsened slightly. Conclusions: This study presented the characteristics of idiopathic pulmonary fibrosis patients treated by Korean medical therapies, and further studies of Korean medical treatments for idiopathic pulmonary fibrosis patients would be valuable.

• Journal of Korean Physical Therapy Science
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• v.8 no.1
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• pp.799-811
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• 2001

The purpose of this study was to examine the effects of sensory integration therapy (SIT) on gross motor development and respiratory function of cerebral palsy children. The design of this study was one-group pre-and post-test design. Subjects of the study were arbitrarily chosen based on predetermined selection criteria among the cerebral palsy children who were treated as out-patients at one rehabilitation hospital in Kyunggi-do. The study was conducted between early April and late July in 2000. Twelve children were in the experimental group. A five-step SIT program was devised from a combination of SIT programs suggested by Ayres(1985) and Fink(1989), and an author-designed SIT program for cerebral palsy children. The experimental group was subjected to 20 to 30 minutes of SIT per session, two sessions a week for ten-week period. Collected data were statistically analyzed by SPSS PC for Wilcoxon signed rank test, and paired t-test. The results were as follows: 1. In gross motor development, post-experimental gross motor scores were higher compared to pre-experimental scores with statistical significance. 2. In respiratory function, post-experimental forced capacity vital scores were higher compared to pre-experimental scores with statistical significance. In conclusion, SIT was found to be effective in gross motor development and respiratory function. But, for the more effectiveness of SIT on gross motor development and respiratory function, further studies employing longer-time experiments are recommended.

• Physical Therapy Rehabilitation Science
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• v.11 no.3
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• pp.350-355
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• 2022

Objective: The purpose of this study is to find out whether people still have problems with breathing after being quarantined for a certain period after being infected with COVID-19. Design: Two-group pretest-posttest design. Methods: A total of 36 subjects were included in this study. Subjects who have been quarantined after being infected with COVID-19 (the after-quarantine group, n=18) and those who have never had COVID-19 (the healthy group, n=18). Respiratory function was evaluated by subjects in resting state and after treadmill exercise. Subjects performed treadmill exercise at moderate intensity for 20 minutes. To compare the differences in respiratory function between groups, forced vital capacity (FVC), forced expiratory volume in first second (FEV1), and maximum voluntary ventilation (MVV) were evaluated using a spirometer. Results: The result of the study, there was a significant difference in FVC in the after-quarantine group between resting and after treadmill exercise (p<0.05). In the healthy group, there was no significant difference in respiratory functions between resting and after treadmill exercise. Conclusions: The meaning of this result is that people who have been quarantined with COVID-19 have lower respiratory function than healthy people who are not infected with COVID-19.

• Tuberculosis and Respiratory Diseases
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• v.70 no.3
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• pp.199-205
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• 2011

Social welfare services for respiratory-disabled persons in Korea are offered based on the respiratory impairment grade, which is determined by 3 clinical parameters; dyspnea, forced expiratory volume in 1 second ($FEV_1$), and arterial oxygen tension. This grading system has several limitations in the objective assessment of respiratory impairment. We reviewed several guidelines for the evaluation of respiratory impairment and relevant articles. Then, we discussed a new grading system with respiratory physicians. Both researchers and respiratory physicians agreed that pulmonary function tests are essential in assessing the severity of respiratory impairment, forced vital capacity (FVC), $FEV_1$ and single breath diffusing capacity ($DL_{co}$) are the primarily recommended tests. In addition, we agreed that arterial blood gas analysis should be reserved for selected patients. In conclusion, we propose a new respiratory impairment grading system utilizing a combination FVC, $FEV_1$ and $DL_{co}$ scores, with more social discussion included.

• The Journal of Korean Medicine
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• v.22 no.1
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• pp.96-103
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• 2001

Clinical symptoms of stroke patients vary widely, and include headache, dizziness, vomiting, dysphagia, dysphasia, incontinence, confusion, chest discomfort, dyspnea etc. Stroke patients who had chronic respiratory disease or had tracheostomy cannula usually have high levels of sputum, but there have been rare clinical reports about treatment of oriental medicine. High levels of sputum in stroke patients can cause pneumonia and dyspnea, and so can delay rehabilitation. By use of Haepyoleejin-tang.Jungchun-tang with change of Ephedrae Herba capacity, we could improve sputum secretion and respiratory function of two stroke patients, and so we report on the clinical course of two stroke patients with high levels of sputum.

• Journal of International Academy of Physical Therapy Research
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• v.2 no.2
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• pp.301-307
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• 2011

The purpose of this study was an determine whether elastic band on treadmill training might effect the chest expansion and pulmonary function of the 20's men. 40 subjects with experimental group(male: 20) and control group(male: 20) was participated in experiment. During four weeks, each group participated thirty minutes for three times per week. Subjects were assessed using pre-value and post-value measurement chest length(chest length for resting, chest expansion) and pulmonary function(forced vital capacity, forced expiratory volume at one second, FEV1/FVC, peak expiratory flow, vital capacity, tidal volume, expiratory reserve volume, inspiratory reserve volume) by the CardioTouch 3000S(BIONET, USA). These findings suggest that experimental group can be used to improve chest expansion, pulmonary function than control group. In comparison of both groups, post-test was more improved in experimental group. In conclusion, experimental group helped improving function of pulmonary volume and respiratory muscle, and thus it indicates that the functions will be more improved through the continued respiratory exercise program.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.2
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• pp.221-230
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• 2023

Purpose : This study was performed to evaluate the effects of virtual reality combined robot assist gait training (VRG) on improvement of balance and respiratory function in chronic stroke patients. Methods : A single-blind, randomized controlled trial (RCT) was conducted with 35 chronic stroke patients. They were randomly allocated 2 groups; VRG group (n=18) and conservative treatment group (CG; n=17). The VRG group received 30 minutes robot assisted gait training combined virtual reality training, robot assisted gait training was conducted in parallel using a virtual reality device (2 sessions of 15 minutes in a 3D-recorded walking environment and 15 minutes in a downtown walking environment). In the conservative treatment group, neurodevelopmental therapy and exercise therapy were performed according to the function of stroke patients. Each group performed 30 minutes a day 3 times a week for 8 weeks. The primary outcome balance and respiratory function were measured by a balance measurement system (BioRescue, Marseille, France), Berg balance scale, functional reach test for balance, Spirometry (Cosmed Micro Quark, Cosmed, Italy) for respiratory function Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV₁), and maximum expiratory volume (PEF) were measured according to the protocol. The measurement were performed before and after the 8 weeks intervention period. Results : Both groups demonstrated significant improvement of outcome in balance and respiratory function during intervention period. VRG revealed significant differences in balance and respiratory function as compared to the CG groups (p<.05). Our results showed that VRG was more effective on balance and respiratory function in patients with chronic stroke. Conclusion : Our findings indicate that VRG can improve balance and respiratory function, highlight the benefits of VRG. This study will be able to be used as an intervention data for recovering balance and respiratory function in chronic stroke patients.

• Journal of the Korean Society for Nondestructive Testing
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• v.25 no.4
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• pp.268-273
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• 2005

The spirometer is a medical device that measures the instantaneous velocity of the respiratory gas flow capacity. It is used for testing the condition of the lung and patient monitoring. It measures the absolute capacity difference that includes the flow capacity signal. In this paper, by using an ultrasound sensor that reduce+ the error caused by the inertia and pressure it has improved the transmission and receiving signal. This has enabled patients with weak respiratory to use the spirometer. Also, by using the ARM 920T Processor, a precise and prompt detection system was implemented.