• CELLMED
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• v.8 no.2
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• pp.8.1-8.5
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• 2018

Nitric oxide (NO) is a small diffusible molecule which plays an important role in various physiological activities. NO is a notable molecule, functioning as a cytotoxic agent and cellular messenger. There has been considerable interest in NO production by activated macrophages because this gaseous metabolite plays a fundamental role in the cytotoxic and cytostatic effects of macrophages towards invasive micro-organisms and tumour cells. No is a bioactive free radical that has been implicated in many physiological functions, plays a critical role during inflammation and therefore constitutes a potential target for developing therapeutics for inflammatory diseases. The use of medicinal plants by the population has been an important alternative the resource in the treatment of various diseases. Its growing acceptance in the medical community has been due to the fact that several plants with biological activities have been scientifically investigated and their efficacy and safety have been proven. In this review, discussed suppressive effects of No production by traditional medicines in RAW 264.7 and THP-1 macrophages.

• 한국신재생에너지학회:학술대회논문집
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• 2006.11a
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• pp.230-233
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• 2006

Small hydropower, one of renewable energies, is the clean energy which emits no carbonic acid gas. It has noting to do with global warming. It is a useful resource to contribute to the dispersion of power. Because of ballooning oil prices, the need for small hydropower is increasing. Recently small hydropower development using dams, small rivers, reservoirs, water pipes, sewage treatment plants and cool ing water of thermal power plants is conducting. By suggesting the strategy of the enlargement revitalization of small hydropower development, we hope to waken the people's interest in the small hydropower

• Journal of the Korean Operations Research and Management Science Society
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• v.33 no.1
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• pp.117-129
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• 2008

Make-to-order manufacturers with multiple plants at multiple sites need to have the ability to quickly determine which plant will produce which customer order to meet the due date and minimize the transportation cost from the plants to the customer. Balancing the work loads and minimizing setups and make-span are also of great concern. Solving such scheduling problems usually takes a long time. We propose a new approach, which we call 'preprocessing', for resolving such complex problems. In preprocessing scheme, a 'good' a priori schedule is prepared and maintained using unconfirmed order information. Upon the confirmation of orders. the preprocessed schedule is quickly modified to obtain the final schedule. We present a preprocessing solution algorithm for multi-site constraint scheduling problem (MSCSP) using genetic algorithm; and conduct computational experiments to evaluate the performance of the algorithm.

• Journal of the Korean Solar Energy Society
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• v.33 no.4
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• pp.46-50
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• 2013

This paper investigated wind turbine degradation quantitatively by analyzing the short-term operation records of the Shinan Wind Power Plant. Instead of a capacity factor which is needed to be normalized its variability due to monthly wind speed change, this study suggests an analysis method by taking the difference between the theoretical power output calculated from the nacelle wind speed and actual power output as the quantitative index of performance degradation. For three-year SCADA data analysis of the Shinan Wind Power Plant, it was confirmed that power output degradation rate of 0.54% per year. This value is within the average reduction rate 0.4%/year~0.9%/year of normalized capacity factor of the onshore wind power plants in U.K. and Denmark; however, lower than the rate 2%/year of Canadian wind power plants.

• Journal of People, Plants, and Environment
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• v.22 no.3
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• pp.241-253
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• 2019

This study presents the standards for desirable local transfer of public affairs by analyzing the perceptions of experts in the academia and research institutes, as well as public officials in the environmental sector in charge of environmental affairs. The results of this study tend to be partially consistent with the results of previous studies that there is a difference in perception among respondents depending on the affiliation of experts and public officials. Among the policy tasks, there was a statistically significant difference among the respondents in perception of responsible agent for carrying out sustainable land planning and management. Regarding general environmental affairs, there was a statistically significant difference among pubic officials in different affiliations in perception of responsible executive agent for natural environment, living environment, and resource circulation.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.244-249
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• 2023

Artemisia keiskeana and A. stolonifera are plants of the genus Artemisia, distributed in various regions, especially China and Korea. They are renowned as medicinal plants with biological and pharmacological activities. Fraxidin, isofraxidin, and daphnoretin are coumarins present in Artemisia spp.; however, research on them is limited. Therefore, this study was carried out to quantify the content of these compounds in the aerial parts of A. keiskeana and A. stolonifera in different regions in Korea. High-performance liquid chromatography was performed with a photodiode array detector and a reverse-phase INNO column. A. stolonifera only contained fraxidin with the highest amount found in Yongmun commune. A. keiskeana cultivation in Soyang commune gave the highest fraxidin and daphnoretin content. However, isofraxidin was not present in all samples. The findings suggest that the concentrations of the three compounds may differ depending on the growth site and provide a foundation for future studies.

• Journal of Ginseng Research
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• v.33 no.1
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• pp.55-58
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• 2009

Generally, the direct sequencing through PCR is faster, easier, cheaper, and more practical than clone sequencing. Frequently, standard PCR amplification is usually interpreted by mispriming internal or external regions of the target template. Normally, DNA fragments were eluted from the gel using Gel extraction kit and subjected to direct sequencing or cloning sequencing. Cloning sequencing has often troublesome and needs more time to analyze for many samples. Since touchdown (TD) PCR can generate sufficient and highly specific amplification, it reduces unwanted amplicon generation. Accordingly, TD PCR is a good method for direct sequencing due to amplifying wanted fragment. In plants the 5S-rRNA gene is separated by simple spacers. The 5S-rRNA gene sequence is very well-conserved between plant species while the spacer is species-specific. Therefore, the sequence has been used for phylogenetic studies and species identification. But frequent occurrences of spurious bands caused by complex genomes are encountered in the product spectrum of standard PCR amplification. In conclusion, the TD PCR method can be applied easily to amplify main 5S-rRNA and direct sequencing of panax ginseng cultivars.

• The Plant Pathology Journal
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• v.35 no.6
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• pp.575-584
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• 2019

Colletotrichum acutatum is a species complex responsible for anthracnose disease in a wide range of host plants. Strain C. acutatum KC05, which was previously isolated from an infected pepper in Gangwon Province of South Korea, was reidentified as C. scovillei using combined sequence analyses of multiple genes. As a prerequisite for understanding the pathogenic development of the pepper anthracnose pathogen, we optimized the transformation system of C. scovillei KC05. Protoplast generation from young hyphae of KC05 was optimal in an enzymatic digestion using a combined treatment of 2% lysing enzyme and 0.8% driselase in 1 M NH₄Cl for 3 h incubation. Prolonged incubation for more than 3 h decreased protoplast yields. Protoplast growth of KC05 was completely inhibited for 4 days on regeneration media containing 200 ㎍/ml hygromycin B, indicating the viability of this antibiotic as a selection marker. To evaluate transformation efficiency, we tested polyethylene glycol-mediated protoplast transformation of KC05 using 19 different loci found throughout 10 (of 27) scaffolds, covering approximately 84.1% of the entire genome. PCR screening showed that the average transformation efficiency was about 17.1% per 100 colonies. Southern blot analyses revealed that at least one transformant per locus had single copy integration of PCR-screened positive transformants. Our results provide valuable information for a functional genomics approach to the pepper anthracnose pathogen C. scovillei.

• Korean Journal of Medicinal Crop Science
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• v.17 no.1
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• pp.46-53
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• 2009

Schizonepeta spike (Korean name "Hyung-Gae") has been used for oriental medicinal purposes in Korea, China and Japan. In this study, twenty six "Hyung-Gae" samples were collected including nine certified Schizonepeta tenuifolia plants, and seventeen commercially marketed "Hyung-Gae" products. Chloroplast trnL-F and rDNA ITS regions of the "Hyung-Gae" samples were sequenced and used to identify whether the samples were genuine S. tenuifolia or not. As the result, the trnL-F and ITS sequences of all the "Hyung-Gae" samples were shown to be identical and it was proven that commercially available medicinal products "Hyung-Gae" are genuine S. tenuifolia. Phylogenetic tree of S. tenuifolia using the trnL-F sequences was constructed and compared with phylogenetic tree using ITS of rDNA region sequences. In these tree, S. tenuifolia was affiliated in the family Lamiaceae. It is proven that trnL-F and ITS phylogenetic trees are useful to study taxonomic position of S. tenuifolia.

• Journal of the Korean Solar Energy Society
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• v.39 no.6
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• pp.113-125
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• 2019

With the opening of the small power brokerage business market in December 2018, the small power trading market has started in Korea. Operators must submit the day-ahead estimates of power output and receive incentives based on its accuracy. Therefore, the accuracy of power generation forecasts is directly affects profits of the operators. The forecasting process for power generation can be divided into two procedure. The first is to forecast solar irradiation and the second is to transform forecasted solar irradiation into power generation. There are two methods for transformation. One is to simulate with physical model, and another is to use regression model. In this study, we found the best-fit regression model by analyzing hourly data of PV output and solar irradiation data during three years for 242 PV plants in Korea. The best model was not a linear model, but a sigmoidal model and specifically a Gompertz model. The combined linear regression and Gompertz curve was proposed because a the curve has non-zero y-intercept. As the result, R² and RMSE between observed data and the curve was significantly reduced.