Journal of Applied Biological Chemistry

  • Volume 66
  • /
  • Pages.244-249
  • /
  • 2023
  • /
  • 1976-0442(pISSN)
  • /
  • 2234-7941(eISSN)
The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Quantitative analysis of coumarins in Artemisia keiskeana and A. stolonifera using HPLC/PDA

  • Gia Han Tran (Department of Plant Science and Technology, Chung-Ang University) ;
  • Hyejin Cho (Department of Plant Science and Technology, Chung-Ang University) ;
  • Jae Min Chung (Department of Forest Resource Conservation, Korea National Arboretum) ;
  • Sanghyun Lee (Department of Plant Science and Technology, Chung-Ang University)
  • Received : 2023.04.14
  • Accepted : 2023.05.24
  • Published : 2023.12.31
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Abstract

Artemisia keiskeana and A. stolonifera are plants of the genus Artemisia, distributed in various regions, especially China and Korea. They are renowned as medicinal plants with biological and pharmacological activities. Fraxidin, isofraxidin, and daphnoretin are coumarins present in Artemisia spp.; however, research on them is limited. Therefore, this study was carried out to quantify the content of these compounds in the aerial parts of A. keiskeana and A. stolonifera in different regions in Korea. High-performance liquid chromatography was performed with a photodiode array detector and a reverse-phase INNO column. A. stolonifera only contained fraxidin with the highest amount found in Yongmun commune. A. keiskeana cultivation in Soyang commune gave the highest fraxidin and daphnoretin content. However, isofraxidin was not present in all samples. The findings suggest that the concentrations of the three compounds may differ depending on the growth site and provide a foundation for future studies.

Keywords

Acknowledgement

This research was supported by the "Studies on Method Development of Application of Native Plant Resources based on Ethnobotanical Traditional Knowledge in Korea" program, Korea National Arboretum, Pocheon, Republic of Korea.

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