• 한국전산유체공학회:학술대회논문집
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• 2008.03a
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• pp.297-301
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• 2008

The flight vehicles have cavities such as wheel wells and bomb bays. The flow around a cavity is characterized as unsteady flow because of the formation and dissipation of vortices due to the interaction between the freestream shear layer and cavity internal flow, the generation of shock and expansion waves. Resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. The flow field is observed to oscillate in the "shear layer mode" with low aspect ratio. In the present study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's $\kappa$-$\omega$ turbulence model. The flow field is observed to oscillate in the shear layer mode" with large aspect ratio. Based on the SPL(Sound Pressure Level) analysis of the pressure variation at the cavity trailing edge, the dominant frequency was analyzed and compared with the results of Rossiter's formul. The aero-acoustic wave analyzed with CPD(Correlation of Pressure Distribution).

• KSCE Journal of Civil and Environmental Engineering Research
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• v.13 no.2
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• pp.1-10
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• 1993

Frequency response functions(FRF) are the most fundamental data for the frequency domain identifications of structural systems. In this paper, an improved method for estimating FRF's is presented. The new FRF estimator takes the weighted average of two conventional estimators, $H_1$(f) and $H_2$(f), utilizing the fact that $H_2$(f) gives more accurate estimate at resonance, while $H_1$(f) yields better results at antiresonances. Based on the estimated FRF's, the modal parameters of the structures, such as, natural frequencies, damping ratios and mode shapes, are also estimated. The effectiveness of the proposed method is investigated through numerical and experimental studies. The estimated results indicate that the proposed estimator gives more accurate results than other estimators.

• BMB Reports
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• v.49 no.8
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• pp.431-436
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• 2016

Human papillomavirus (HPV) is the major cause of cervical cancer, a deadly threat to millions of females. The early oncogene product (E7) of the high-risk HPV16 is the primary agent associated with HPV-related cervical cancers. In order to understand how E7 contributes to the transforming activity, we investigated the structural features of the flexible N-terminal region (46 residues) of E7 by carrying out N-15 heteronuclear NMR experiments and replica exchange molecular dynamics simulations. Several NMR parameters as well as simulation ensemble structures indicate that this intrinsically disordered region of E7 contains two transient (10-20% populated) helical pre-structured motifs that overlap with important target binding moieties such as an E2F-mimic motif and a pRb-binding LXCXE segment. Presence of such target-binding motifs in HPV16 E7 provides a reasonable explanation for its promiscuous target-binding behavior associated with its transforming activity.

• 한국전산유체공학회:학술대회논문집
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• 2008.10a
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• pp.297-301
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• 2008

The flight vehicles have cavities such as wheel wells and bomb bays. The flow around a cavity is characterized as unsteady flow because of the formation and dissipation of vortices due to the interaction between the freestream shear layer and cavity internal flow, the generation of shock and expansion waves. Resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. The flow field is observed to oscillate in the "shear layer mode" with low aspect ratio. In the present study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's ${\kappa}-{\varepsilon}$ turbulence model. The flow field is observed to oscillate in the "shear layer mode" with large aspect ratio. Based on the SPL(Sound Pressure Level) analysis of the pressure variation at the cavity trailing edge, the dominant frequency was analyzed and compared with the results of Rossiter's formul. The aero-acoustic wave analyzed with CPD(Correlation of Pressure Distribution).

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2009.04a
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• pp.280-281
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• 2009

Piezoelectric vibrators can be good replacements of electric motors to excite touch screen of a mobile device owing to small volume and low power consumption. One problem to be solved yet for real application is larger excitation force or moment than available currently. More efficient excitation by a piezoelectric vibrator could be achieved by operating at one of resonance frequencies of the system, which must also be as close as possible to frequency range where index finger is most sensitive and increasing transmission force or moment at that frequency. In this study, dynamic models are derived for the piezoelectric exciter and an adhesive viscoelastic layer, which connect the exciter to the screen. The adhesive layer is modeled as distributed stiffness by considering its geometric shape to relative to the piezoelectric exciter. Then, equations of motion for the piezoelectric exciter and the adhesive layer are derived using Hamilton's principle. Based on this model, dynamic characteristics of the exciter will be designed to maximize the force or moment transmitted onto the screen structure.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.10 no.2
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• pp.221-225
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• 2007

A previously healthy 3-year-old girl was admitted to the Department of Pediatrics in Severance Hospital with sudden symptoms of melena. The vital signs were stable, and splenomegaly was found in a physical examination. The patient had moderate thrombocytopenia. There was no evidence of autoimmune disease. A upper gastrointestinal endoscopy and esophagogram showed a varix on the lower esophagus. Coarse liver parenchymal echoes and increased periportal echogenicity were seen on a Doppler sonogram. The velocity of the portal vein mildly increased. Magnetic-resonance-cholangiopancreatogram (MRCP) demonstrated normal portal structures. A sono-guided liver biopsy was performed, but the pathological findings were unremarkable. Based on these findings, we diagnosed the patient with idiopathic portal hypertension. The patient was discharged and was treated with oral beta blocker. We report a case of idiopathic portal hypertension with a brief review of the literature.

• Korean Journal of Agricultural Science
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• v.47 no.1
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• pp.183-191
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• 2020

Lichens are composite organisms consisting of a symbiotic association of a fungus with a photosynthetic partner (the photobiont or phycobiont), usually either a green alga or cyanobacterium. According to more recent studies, the biological activities of lichens and lichen substances include an antibiotic activity, antitumor and antimutagenic activity against human immunodeficiency virus (HIV), allergenic activity, plant growth inhibitory activity, and enzyme inhibitory activity. This study screened lichen extracts with a potent in vitro antifungal activity against plant diseases caused by phytopathogenic fungi. The compounds were isolated from Stereocaulon alpinum and Sphaerophorus globosus, and their chemical structures were identified as methyl hematommate, methyl β-orsellinate, 5-hydroxyferulic acid, sphaerophorin, and 2-heptyl-4,6-dimethoxybenzoic acid by electron ionization mass spectrometry (EI-MS) and nuclear magnetic resonance (NMR) spectral analyses. In vitro disease control against Alternaria mali, Cochliobolus miyabeanus, Colletotrium gloeosporioides, and Verticillum dahliae was evaluated. And among the five compounds, only methyl hematommate was effective against A. mali, C. miyabeanus, and C. gloeosporioides. The compounds were isolated from these lichens, which have a similar biosynthetic pathway, respectively. This is the first report of these compounds being isolated from these lichens.

• Journal of KSNVE
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• v.6 no.2
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• pp.215-224
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• 1996

Active vibration control is generally used to reduce vibration level by the actuators based on measured signal. Dynamic properties of a structure can be easily modified by the active vibration control, so that the vibration level may be effectively reduced to the magnitude below the allowable limit over a wide frequency rangs. In this paper, an instantaneous optimal control algorithm including acceleration feedback is presented for the active vibration control of large structures considering facts that the acceleration response can be easily measured, but the displacement and velocity response are obtained by numerically integrating the measured acceleration response with some errors. The adverse effect of the time delay is overcomed by taking into account the dynamic characteristics of an actuator and filters in the design of controller. Performance test is carried out using a hydraulic active mass driver on a test structure$(L{\times}W{\times}H;=;1200mm{\times}800mm{\times}1600mm, about;500kg)$ supported by four columns under base excitations. It is confirmed that the vibration level of the test structure are reduced to about 1/6 near resonance.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.24 no.3
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• pp.219-226
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• 2014

A bus duct system for wind tower is introduced. A marine cable has been widely used in wind tower or various offshore structures. However, as the electric load capacity is increases, large number of cable lines must be used to cover the huge amount of electric capacities. Therefore, the installation of the cable lines becomes very difficult due to the heavy weight and volume of the cables. On the other hand, by using a single bus duct system line, the power capacity amount of 16 cables can be delivered with significantly compacted form. However, unlike flexible cables, the bus duct is relatively stiff which could generate the resonance phenomenon in the operating condition of the wind tower. In this study, the vibration characteristics of the bus duct are investigated and its long-term reliability during the life time of the wind tower is verified.

• Wind and Structures
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• v.24 no.1
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• pp.79-93
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• 2017

Wind-induced fluctuating internal pressures in a building with a dominant opening can be described by a second-order non-linear differential equation. However, the accuracy and efficiency of the governing equation in predicting internal pressure fluctuations depend upon two ill-defined parameters: inertial coefficient $C_I$ and loss coefficient $C_L$, since $C_I$ determines the un-damped oscillation frequency of an air slug at the opening, while $C_L$ controls the decay ratio of the fluctuating internal pressure. This study particularly focused on the value of loss coefficient and its influence factors including: opening configuration and location, internal volumes, as well as wind speed and approaching flow turbulence. A simplified formula was presented to predict loss coefficient, therefore an approximate relationship between the standard deviation of internal and external pressures can be estimated using Vickery's approach. The study shows that the loss coefficient governs the peak response of the internal pressure spectrum which, in turn, will directly influence the standard deviation of the fluctuating internal pressure. The approaching flow characteristic and opening location have a remarkable effect on the parameter $C_L$.