• Proceedings of the KSMRM Conference
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• 대한자기공명의과학회 2008년도 MR연수강좌
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• pp.170-202
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• 2008

• Investigative Magnetic Resonance Imaging
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• 제7권1호
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• pp.31-38
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• 2003

Purpose : To analyze the serial changes of proton magnetic resonance (MR) spectra in the abscess and to determine the effect of the antibiotic treatment on the metabolite patterns. Materials and Methods : MR imaging and MR spectroscopy of an experimentally induced abscess were performed sequentially for four weeks at interval of one week in both the control group (n=5) and the antibiotic treatment group (n=5). On MR imaging, the shape and the size of the abscess were analyzed. On MR spectroscopy, the resonance peaks of metabolites were assigned on the basis of reported peaks in the literature. The metabolite ratios measured by using N-acetyl alanine as an external reference and by using lipid as an internal reference were compared in both the control and treatment g roups. Results : The abscesses were seen as cystic masses on MR imaging. On MR spectroscopy, the variable peaks of acetate, succinate and various amino acids, which are the metabolites of infection, were identified in the control and antibiotic treatment groups. The most frequent peak was that of acetate at 1.92ppm (70%). Both the peak ratios of acetate to lipid and acetate to external reference tended to decrease in the treatment group while the ratios did not change significantly in the control group. Conclusion : MR spectroscopy is useful not only for the diagnosis of abscess but also for monitoring the evolution of the abscess by using the acetate peak.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• 제20권1호
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• pp.22-28
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• 2010

Approximate analysis for a building installed with a friction damper is performed to get insight of its dynamic behavior. Energy balance equation is used to have a closed analytical form solution of dynamic magnification factor(DMF). It is found out that DMF is dependent on friction force ratio and resonance frequency. Approximation of DMF and equivalent damping ratio of a friction damper is proposed with such assumption that the building with a friction damper shows harmonic steady-state response and narrow banded response behavior near resonance frequency. Linear transfer function from input external force to output building displacement is suggested from the simplified DMF equation. Root mean square of a building displacement is derived under earthquake-like random excitation. Finally, design procedure of a friction damper is proposed by finding friction force corresponding to target control ratio. Numerical analysis is carried out to verify the proposed design procedure.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 한국소음진동공학회 2008년도 추계학술대회논문집
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• pp.264-269
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• 2008

This paper presents the summary of control of abnormal vibration found in the COP motors of a nuclear power plant. All six identical units of COP pump-motor assemblies showed unstable vibration pattern of which one or two showed higher vibration enough to exceed the allowable level from the installation stage. Many trials of test, measurement, overhaul and replacement had been repeated to investigate and solve the problem but only to reach unsatisfactory settlement. Recently several times of site tests are made and followed by significant diagnostic actions in which the authors group participated. It was found that the coupled shafting system of motor and pump is in close resonance with the $1^{st}$ shaft rotating speed. Redesign of topside motor bearing clearance is made to increase bearing stiffness and hence to avoid the resonance which consequently led to reduce the troubled vibration to allowable and stable status.

• Journal of the Korean Magnetic Resonance Society
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• 제15권1호
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• pp.54-68
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• 2011

$^1H$ nuclear magnetic resonance (NMR) spectroscopy of biological samples has been proven to be an effective and nondestructive approach to probe drug toxicity within an organism. In this study, ketoprofen toxicity was investigated using $^1H$-NMR spectroscopy coupled with multivariate statistical analysis. Histopathologic test of ketoprofen-induced acute gastrointestinal damage in rats demonstrated a significant dose-dependent effect. Furthermore, principal component analysis (PCA) derived from $^1H$-NMR spectra of urinary samples showed clear separation between the vehicle-treated control and ketoprofen-treated groups. Moreover, PCA derived from endogenous metabolite concentrations through targeted profiling revealed a dose-dependent metabolic shift between the vehicle-treated control, low-dose ketoprofen-treated (10 mg/kg body weight), and high-dose ketoprofen-treated (50 mg/kg) groups coinciding with their gastric damage scores after ketoprofen administration. The resultant metabolic profiles demonstrated that the ketoprofen-induced gastric damage exhibited energy metabolism perturbations that increased urinary levels of citrate, cis-aconitate, succinate, and phosphocreatine. In addition, ketoprofen administration induced an enhancement of xenobiotic activity in fatty oxidation, which caused increase levels of N-isovalerylglycine, adipate, phenylacetylglycine, dimethylamine, betaine, hippurate, 3-indoxylsulfate, N,N-dimethylglycine, trimethyl-N-oxide, and glycine. These findings demonstrate that $^1H$-NMR-based urinary metabolic profiling can be used for noninvasive and rapid way to diagnose adverse drug effects and is suitable for explaining the possible biological pathways perturbed by nonsteroidal anti-inflammatory drug toxicity.

• Proceedings of the Korean Vacuum Society Conference
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.567-567
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• 2013

Surface plasmon resonance is the enhancement of electromagnetic wave caused by oscillation on the metal and dielectric interfaces. Surface plasmons with nanohole arrays provides an enhancedresonance for the specific wavelengths of interests. Asymmetric array of nanoscale structures can enable orientation dependent shift of resonance wavelengths when combined with the control of polarization for incident visible light, thus providing color tunability. Appropriate lattice constants along the direction of polarization in rectangular nanohole arrays can determine the resonance condition generating red (R), green (G), and blue (B) colors and potentially be applied to display applications. In ourprevious report, we have optimized the ion beam nanomachining conditions to fabricate the nanostructures on the metal film. We apply the fabrication conditions to make nanoscale hole arrays using 100 nm thick gold layer on the glass substrate with the optimal design of periodicities along x, y, and diagonal directions of a=440 nm, b=520 nm, c=682 nm, and the hole diameter of d=200 nm. Using the reflective light in dark field mode of optical microscope, we can observe different colors. When the polarizer is paralleled along a, b, or c direction, the represented color is changed to R, G, and B, respectively. We further map the color using i1 to correlate the conditions of the nanohole arrays with their characteristic color.

• Transactions of the Korean Society of Mechanical Engineers B
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• 제25권9호
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• pp.1272-1280
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• 2001

An experimental study has been conducted to elucidate the resonance of natural convection in a side-heated square enclosure having a mechanically oscillating bottom wall. Under consideration is the impact of the imposed oscillating frequency, amplitude and the system Rayleigh number on the fluctuation of air temperatures. The experimental results show that the magnitude of the fluctuation of air temperature is substantially augmented at a specific forcing frequency of the oscillating bottom wall. The resonant frequency is increased with the increase of the Rayleigh number and it is little affected by the amplitude of the oscillating wall. It is also found that the resonant frequency is relevant to the Brunt- V$\"{a}$iS$\"{a}$l$\"{a}$ frequency which represents the stratification degree of the system.

• Journal of Power Electronics
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• 제11권3호
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• pp.311-318
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• 2011

LCL filters installed at converter outputs offer a higher harmonic attenuation than L filters. However, as a three order resonant circuit, it is difficult to stabilize and has a risk of oscillating with the power grid. Therefore, careful design is required to damp LCL resonance. Compared to a passive damping method, an active damping method is a more attractive solution for this problem, since it avoids extra power losses. In this paper, the damping capabilities of capacitor current, capacitor voltage, and grid-side current feedback methods, are analyzed under the discrete-time state-space model. Theoretical analysis shows that the grid-side current feedback method is more suitable for use in active power filters, because it can damp LCL resonance more effectively than the other two methods when the ratio of the resonance and the control frequency is between 0.225 and 0.325. Furthermore, since there is no need for extra sensors for additional states measurements, this method provides a cost-efficient solution. To support the theoretical analysis, the proposed method is tested on a 7-kVA single-phase shunt active power filter.

• Animal Bioscience
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• 제34권4호
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• pp.724-733
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• 2021

Objective: The objectives of this study were to investigate the direct antioxidative effect of 90 Kda heat shock protein (Hsp90) obtained from duck muscle. Methods: The interaction of Hsp90 with phospholipids and oxidized phospholipids was studied with surface plasmon resonance (SPR), and their further oxidation in the presence of Hsp90 was evaluated with thiobarbituric acid reactive substances (TBARS) assay. The scavenging effect on the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis (3-ethylbenzthiazoline-6-sulfonic acid (ABTS) was measured, and the electron paramagnetic resonance (EPR) spectroscopy in combination with 5-tert-Butoxycarbonyl-5-methyl-1-pyrroline-N-oxide and 2-phenyl-4,4,5,5,-tetramethylimidazoline-1-oxyl-3-oxide (PTIO) was utilized to determine the abilities of Hsp90 in scavenging hydroxyl and PTIO radicals. Results: SPR showed Hsp90 could bind with both phospholipids and oxidized phospholipids, and prevent their further oxidation by the TBARS assay. The DPPH and ABTS scavenging activity increased with Hsp90 concentration, and could reach 27% and 20% respectively at the protein concentration of 50 μM. The EPR spectra demonstrated Hsp90 could directly scavenge ·OH and PTIO· radicals. Conclusion: This suggests that Hsp90, a natural antioxidant in meat, may play an important role in cellular defense against oxidative stress, and may have potential use in meat products.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• 제24권1호
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• pp.62-68
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• 2014

Recently, MRI(magnetic resonance imager) scanner is continually used for medical diagnosis and many biomedical researches. When it operates, however, intense noise is generated. The SPL(sound pressure level) of the noise approaches 130 dB especially in 3 T(Tesla) MRI. Meanwhile, more than 3 T MRI scanners have been developed to get higher-resolution images, so louder noise is expected in the future. The intense noise makes patients feel nervous and uncomfortable. Moreover, it could possibly cause hearing loss to patient in extreme cases. For this reason, some active noise control systems have been researched. One of them used feedback Filtered-X LMS(FXLMS) algorithm which is able to control only narrowband noises and possible to diverge in severe case. In this paper, we determine the property of MRI noise. Using the property, we applied a method of open-loop and adaptive control for reducing MRI noise at target point inside bore. We verified performance of the method with computer simulation and preliminary experiment. The results demonstrate that the method can effectively reduce MRI noise at target point.