• Mycobiology
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• v.45 no.2
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• pp.101-104
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• 2017

We identified two genes related to fungicide resistance in Fusarium fujikuroi through random mutagenesis. Targeted gene deletions showed that survival factor 1 deletion resulted in higher sensitivity to fungicides, while deletion of the gene encoding F-box/WD-repeat protein increased resistance, suggesting that the genes affect fungicide resistance in different ways.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.2
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• pp.95-111
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• 2022

Chronic obstructive pulmonary disease (COPD) is an important healthcare problem worldwide. Often, glucocorticoid (GC) resistance develops during COPD treatment. As a classic hypoglycemic drug, metformin (MET) can be used as a treatment strategy for COPD due to its anti-inflammatory and antioxidant effects, but its specific mechanism of action is not known. We aimed to clarify the role of MET on COPD and cigarette smoke extract (CSE)-induced GC resistance. Through establishment of a COPD model in rats, we found that MET could improve lung function, reduce pathological injury, as well as reduce the level of inflammation and oxidative stress in COPD, and upregulate expression of nuclear factor E2-related factor 2 (Nrf2), heme oxygenase-1 (HO-1), multidrug resistance protein 1 (MRP1), and histone deacetylase 2 (HDAC2). By establishing a model of GC resistance in human bronchial epithelial cells stimulated by CSE, we found that MET reduced secretion of interleukin-8, and could upregulate expression of Nrf2, HO-1, MRP1, and HDAC2. MET could also increase the inhibition of MRP1 efflux by MK571 significantly, and increase expression of HDAC2 mRNA and protein. In conclusion, MET may upregulate MRP1 expression by activating the Nrf2/HO-1 signaling pathway, and then regulate expression of HDAC2 protein to reduce GC resistance.

• New & Renewable Energy
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• v.4 no.2
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• pp.74-80
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• 2008

To improve the blue responses of screen-printed single crystalline silicon solar cells, we investigated an emitter etch-back technique to obtain high emitter sheet resistances, where the defective dead layer on the emitter surface was etched and became thinner as the etch-back time increased, resulting in the monotonous increase of short circuit current and open circuit voltage. We found that an optimal etch-back time should be determined to achieve the maximal performance enhancement because of fill factor decrease due to a series resistance increment mainly affected by contact and lateral resistance in this case. To elucidate the reason for the fill factor decrease, we studied the resistance analysis by potential mapping to determine the contact and the lateral series resistance. As a result, we found that the fill factor decrease was attributed to the relatively fast increase of contact resistance due to the dead layer thinning down with the lowest contact resistivity when the emitter was contacted with screen-printed silver electrode.

• 한국신재생에너지학회:학술대회논문집
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• 2008.05a
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• pp.390-393
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• 2008

To improve the blue responses of screen-printed single crystalline silicon solar cells, we investigated an emitter etch-back technique to obtain high emitter sheet resistances, where the defective dead layer on the emitter surface was etched and became thinner as the etch-back time increased, resulting in the monotonous increase of short circuit current and open circuit voltage. We found that an optimal etch-back time should be determined to achieve the maximal performance enhancement because of fill factor decrease due to a series resistance increment mainly affected by contact and lateral resistance in this case. To elucidate the reason for the fill factor decrease, we studied the resistance analysis by potential mapping to determine the contact and the lateral series resistance. As a result, we found that the fill factor decrease was attributed to the relatively fast increase of contact resistance due to the dead layer thinning down with the lowest contact resistivity when the emitter was contacted with screen-printed silver electrode.

• Journal of Advanced Marine Engineering and Technology
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• v.15 no.1
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• pp.51-58
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• 1991

Corrosion fatigue test was performed by the use of plane bending fatigue tester in marine environment having various specific resistance from 25(natural sea water) to 5000.ohm.cm. It is in order to investigate the effects of marine environmental factor on the corrosion fatigue fracture of SS41 steel. The main results obtained are as follows; 1. The aspect ratio(b/a) of corner crack growing in natural sea water is lower than that in air. 2. The surface crack growth rate(da/dN) in marine environment is faster than that in air and da/dN delaies with the specific resistance increased. 3. The experimental constant m of paris rule [da/dN=C(${\delta}$K)$^m$] decrease with the specific resistance decreased and the effect of corrosion in proportion to the specific resistance is more sensitive than that of stress intensity factor range(${\delta}$K) under region II. 4. The accelerative factor(${\alpha}$) in marine environment is about 1.1-2.7 and .alpha. is increase under the low region of stress intensity factor range(${\delta}$K). 5. The electrode potential($E_0$) gets less noble potential with the specific resistance decreased.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.25 no.6
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• pp.100-107
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• 2011

Since transmission and distribution neutral wires are connected with a substation grounding grid, it is very difficult to measure grounding resistance of isolated substation grounding grid after the substation is energized. It is impractical to isolate the grounding grid from other parallel connections such as distribution line neutrals and overhead ground wires for grounding resistance measurement only. In this paper, we proposed and demonstrated a novel measurement method of grounding resistance of isolated substation grounding grid. For this method, grounding current division factor and conventional FOP(Fall-Of-Potential) profiles were measured at power supplying 154[kV] substation. The obtained FOP profile was processed with the measured grounding current division factor to produce the grounding resistance of isolated grounding grid. Simulated FOP profile agreed well with the measured one showing the validity of the proposed method.

• The Journal of the Korea Contents Association
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• v.17 no.12
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• pp.447-460
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• 2017

The purpose of this study is to investigate the factors affecting consumer resistance of smart watches, focusing on consumer groups. SPSS 19.0 was used to conduct a descriptive analysis and multi regression analysis of the data. This study is based on the questionnaire data of 407 consumers. The results of this study are as follows. First, the relative advantage was identified as a factor in reducing consumer resistance across all gender and age groups. Second, complexity has been identified as a factor that increases the consumer resistance of female consumers, and consumer groups in their 20s and 40s. Third, esthetics was found to reduce consumer resistance in men, women, and the consumer group in their 20s. Fourth, subjective norms were identified as a factor reducing consumer resistance in women and in consumer groups in their 20s and 30s. Fifth, the risk of privacy was identified as a factor in increasing consumer resistance in men and the consumer group in their 40s. The results of this study can be helpful to understand consumer resistance to smartwatches.

• Journal of the Korean Geotechnical Society
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• v.31 no.10
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• pp.5-16
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• 2015

Considering the conversion of the Korea Construction Standards to Limit State Design (LSD), we analyzed the resistance bias factor for pullout resistance, as a part of the development of the Load and Resistance Factor Design (LRFD) for soil nailing; very few studies have been conducted on soil nailing. In order to reflect the local characteristics of soil nailing, such as the design and construction level, we collected statistics on pullout tests conducted on slopes and excavation construction sites around the country. In this study a database was built based on the geotechnical properties, soil nailing specifications, and pullout test results. The resistance bias factors are calculated to determine the resistance factor of the pullout resistance for gravity and pressurized grouting method, which are the most commonly used methods in Korea; moreover, we have relatively sufficient data on these methods. We found the resistance bias factors to be 1.144 and 1.325, which are relatively conservative values for predicting the actual ultimate pullout resistance. It showed that our designs are safer than those found in a research case in the United States (NCHRP Report); however, there was an uncertainty, $COV_R$, of 0.27-0.43 in the pullout resistance, which is relatively high. In addition, the pressurized grouting method has a greater margin of safety than the gravity grouting method, and the actual ultimate pullout resistance determined using the pressurized grouting method has low uncertainty.

• Journal of Ocean Engineering and Technology
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• v.7 no.1
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• pp.56-61
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• 1993

Standard values in graphic porms are presented for the ratio of added wave resistance to the sun of added wave and wind resistances in head sea for three ship types, tanker, container ship and passenger ship. The effect of ship length on the ratio defined above is investigated for the three ship types. Obique sea added resistance is determined using wave direction reduction factor. The factor is obtained from model test results and cubic spline interpolation technique.

• International Journal of Highway Engineering
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• v.16 no.6
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• pp.27-37
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• 2014

PURPOSES : The purpose of this study is to verify the causes of surface scaling at L-shoulder concrete structure. METHODS : From the literature reviews, mechanisms of frost damage were studied and material properties including strength, air void, spacing factor and scaling resistance of L-shoulder concrete structure were analyzed using core specimens taken by real fields. RESULTS : The spacing factor of air void has relatively high correlation of surface conditions : lower spacing factor at good surfacing condition and vice versa. If the compressive strength is high, even thought spacing factor does not reach the threshold value of reasonable durability, the surface scaling resistance shows higher value. Based on these test results, the compressive strength also provide positive effect on the surface scaling resistance. CONCLUSIONS : The main causes of surface scaling of L-shoulder could be summarized as unsuitable aid void amount and poor quality of air void structure. Secondly, although the compressive strength is not the governing factor of durability, but it shows the positive effect on the surface scaling resistance.