• Journal of Korean Library and Information Science Society
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• v.48 no.4
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• pp.283-301
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• 2017

Recently, an integrated electronic publishing format that can be used by disabled people and the general public is expected. If applied to national alternative material production strategy, it is expected that not only the problem of alternative material production strategy using existing DTD(Document Type Definition) but also various alternative material corresponding to the demand of consumer can be supplied. In order to cope with changes in the production and management strategy of the substitute materials for the rapidly changing persons with disabilities, it is necessary to develop the substitute materials related to the substitute materials, such as 'production of alternative materials', 'research and education of alternative material', and 'operation of alternative material network' The organization of the National Library for the Disabled should be expanded and reorganized so that a constructed center can be established and demonstrated its expertise.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.27 no.2
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• pp.29-50
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• 2016

This study conducted a survey research in order to prove the influence of public libraries on the creation of social capital. The analysis showed that the use of public libraries is generally focusing on information activities on a personal level and it is not extended to establish social relationships or form social trust between people on social level. If the personal information activities in public libraries are expanded to share information and opinions with other people, however, it can establish social relationships across people mediated by public libraries. It also has the possibilities to induce library users to participate reciprocal activities on social level. As a result, the information activities in public libraries on personal level can be extended to social levels mediated by public libraries, which can affect the creation of social capital. Based on these results, public libraries need to consider the social responsibilities on creating social capital as well as supporting information activities of members of society.

• 한국정보디스플레이학회:학술대회논문집
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• 2005.07b
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• pp.1611-1614
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• 2005

In this paper, a new multi-view 3D video communication system for real-time Reality teleconferencing application is proposed by usin gthe IEEE 1394 digital cameras, Intel Xeon server computer system and Microsoft's DirectShow programming library and its performance is analyzed in terms of image-grabbing frame rate and number of views. The captured two-view image data is compressed by extraction of disparity data between them and transmitted to another client system through the communication network, in which multi-view could be synthesized with this received 2-view data using the intermediate view reconstruction technique and displayed on the multi-view 3D display system. From some experimental results, it is found that the proposed system can display 16-view 3D images with a gray of 8bits and a frame rate of 15fps.

• Journal of the Korean Society for information Management
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• v.33 no.2
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• pp.177-200
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• 2016

The purpose of this study was to analyze how the Library and Information Science (LIS) related research efforts in Korea contributed to the progress of the Human Computer Interaction (HCI) discipline to identify the potential collaboration research partners and topics. The following data was used for the network and frequency analysis: titles, keywords and affiliation information extracted from the Korean journals serving the LIS fields as well as the conference proceedings of the Korean HCI society. Information communication technology, computer engineering, and technology industry had been active in research collaborations but LIS field was comparatively not active. This study was able to determine that LIS researchers carried out important research but they had not much interests in the topics that required interdisciplinary collaboration. However, there were a number of papers, which were not authored by LIS discipline researchers, in the LIS related journals. In addition, there are a few ongoing interdisciplinary research projects which included LIS researchers. This reveals that it is possible for the LIS field could play an important role in the future if the researchers actively participate the collaborative projects.

• IMMUNE NETWORK
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• v.1 no.1
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• pp.7-13
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• 2001

Currently 18 monoclonal antibodies were approved by FDA for inj ection into humans for therapeutic or diagnostic purpose. And 146 clinical trials are under way to evaluate the efficacy of monoclonal antibodies as anti-cancer agents, which comprise 9 % of clinical trials in cancer therapy field. When considering a lot of disappointment and worries existed in this field during the past 15 years, this boom could be called as resurrection. Antibodies have several merits over small molecule drug. First of all it is easier and faster in development, as proper immunization of the target proteins usually raises good antibody response. The side effects of antibodies are more likely to be checked out in immunohistomchemical staining of whole human tissues. Antibody has better pharmacokinetics, which means a longer half-life. And it is non-toxic as it is purely a "natural drug. Vast array of methods was developed to get the recombinant antibodies to be used as drug. The mice with human immunoglobulin genes were generated. Fully human antibodies can be developed in fast and easy way from these mice through immunization. These mice could make even human monoclonal antibodies against any human antigen like albumin. The concept of combinatorial library was also actively adopted for this purpose. Specific antibodies can be screened out from phage, mRNA, ribosomal library displaying recombinant antibodies like single chain Fvs or Fabs. Then the coding genes of these specific antibodies are obtained from the selected protein-gene units, and used for industrial scale production. Both $na\ddot{i}ve$ and immunized libraries are proved to be effective for this purpose. In post-map arena, antibodies are receiving another spotlight as molecular probes against numerous targets screened out from functional genomics or proteomics. Actually many of these antibodies used for this purpose are already human ones. Through alliance of these two actively growing research areas, antibody would play a central role in target discovery and drug development.

• Journal of Korean Library and Information Science Society
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• v.39 no.4
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• pp.479-504
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• 2008

A female marriage immigrant is one of the most remarkable group as Korea entering a multicultural society. It is necessary that they get various supports to become a part of our Korean society, and social services and information accessibility are really important things to give them such supports effectively. This research focused on the problems that female marriage immigrants are facing in their marriage life and a process of adaptation in Korea. This research analyzed the actual conditions and the differences of social services and information accessibility classified by the problems female marriage immigrants are facing, their nationality, and their residence. On the basis of the results, this research provided the ways to raise the level of social services and information accessibility and also optimize social services for them.

• Journal of Microbiology and Biotechnology
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• v.6 no.1
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• pp.54-59
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• 1996

In the research and development of bioactive compounds, determining whether a compound is novel is necessary at almost every stage. Fast and efficient determination can save money, time and effort, and thereby increase efficiency. Analysis and investigation of empirical results for previously determined compounds is also important in such research. The need to communicate research findings between workers is necessary. In effect, a systematic, centralized communication medium is required. Therefore, we have developed and constructed our own database and search systems. We have developed a search system on DOS and constructed a source file for our own database. To support multiple users, we have developed another specific and comprehensive search system, including powerful searching and output management features. The system has been developed to be simple and user-friendly, using the curses library of UNIX, while still allowing complicated queries to be performed easily with simple full-screen facilities. This UNIX version will be available for use by researchers on a computer network and is expected to make numerous contributions to basic research in universities. It will also have direct applications for institutes and industry.

• Archives of design research
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• v.11 no.3
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• pp.79-88
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• 1998

This research was carried out with emphasis on merits of computers as an education medum. Network technologies make collaboration as easy as they work in the same space. It is generally considered that education should be done with adequate contents and effective methods. But, the methods used in computer graphics education are not different from others, and this fact makes a low efficiency. To improve the education environments, design education program is developed. This is designed on the basis of LAN, and partially on the web. The library where design materials for study are stored and the gallery where design works done by students are exhibited are modules that utilize web technologies. Communication between students will become easy by using whiteboard and feedback from various kinds of user will be done by uploading design works on the web. But the program can be used only in the computer oriented subjects now, so further study should be carried out to broaden the scope of design education.

• Animal Bioscience
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• v.35 no.7
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• pp.975-988
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• 2022

Objective: In this study, we aimed to identify long non-coding RNAs (lncRNAs) that play important roles in starvation stress, analyze their functions, and discover potential molecular targets to alleviate starvation stress to provide a theoretical reference for subsequent in-depth research. Methods: We generated a piglet starvation stress animal model. Nine Yorkshire weaned piglets were randomly divided into a long-term starvation stress group (starved for 72 h), short-term starvation stress group (starved for 48 h), and the control group. LncRNA libraries were constructed using high-throughput sequencing of piglet ileums. Results: We obtained 11,792 lncRNAs, among which, 2,500 lncRNAs were novel. In total, 509 differentially expressed (DE)lncRNAs were identified in this study. Target genes of DElncRNAs were predicted via cis and trans interactions, and functional and pathway analyses were performed. Gene ontology functions and Kyoto encyclopedia of genes and genomes analysis revealed that lncRNA-targeted genes mainly participated in metabolic pathways, cellular processes, immune system processes, digestive systems, and transport activities. To reveal the mechanism underlying starvation stress, the interaction network between lncRNAs and their targets was constructed based on 26 DElncRNAs and 72 DEmRNAs. We performed an interaction network analysis of 121 DElncRNA-DEmRNA pairs with a Pearson correlation coefficient greater than 0.99. Conclusion: We found that MSTRG.19894.13, MSTRG.16726.3, and MSTRG.12176.1 might play important roles in starvation stress. This study not only generated a library of enriched lncRNAs in piglets, but its outcomes also provide a strong foundation to screen key lncRNAs involved in starvation stress and a reference for subsequent in-depth research.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.34 no.4
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• pp.29-54
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• 2023

This study aimed to analyze the research trends of journal articles published by medical schools representing Korean modern. A total of 682 were selected from two journals published by Medical College in Keijo and Keijo Imperial University Medical Faculty. In results, the affiliations of authors who participated in Acta Medicinalia in Keijo included various schools and hospitals, and the authors' major was found to be similar in basic medicine and clinical medicine. In The Keijo Journal of Medicine, only school-affiliated authors participated, and 96.33% of the authors were majors in basic medicine. Co-occurrence network analysis was conducted on MeSH terms from the title of the article using MeSH on Demand, and the keyword that derived in both journals was 'erythrocytes', which analyzed the condition of red blood cells according to organs and diseases. In frequency analysis, a common area of research in both journals was the study focusing on blood and blood cells, and the study of anemia and tuberculosis, which were prevalent diseases at the time. As for comparing each journal, Acta Medicinalia in Keijo has focused on inflammatory diseases and clinical pathological studies in humans, and The Keijo Journal of Medicine has focused on anatomical studies on animals and pharmacological studies on medicines. Through this study, it was possible to identify the research topics and major keywords in two medical schools with different founding goals.