• Title/Summary/Keyword: Research Information Systems

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Acute Oral Toxicity and Skin Irritation Studies on Lamia-Kill$^{(R)}$ Composed of Benzalkonium Chloride and Citric Acid (염화벤지코늄과 구연산을 주성분으로 하는 살균 소독제 라미아-킬에 대한 급성경구독성 및 피부자극성 시험에 관한 연구)

  • Cha, Chun-Nam;Lee, Yeo-Eun;Son, Song-Ee;Yoo, Chang-Yeol;Park, Eun-Kee;Choi, Hyun-Ju;Kim, Suk;Lee, Hu-Jang
    • Journal of Food Hygiene and Safety
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    • v.26 no.4
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    • pp.377-382
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    • 2011
  • This test was performed to evaluate the acute oral toxicity and skin irritation of Lamia-Kill$^{(R)}$, disinfectant, containing 20% benzalkonium chloride and 10% citric acid. In acute oral toxicity, Lamia-Kill$^{(R)}$ was orally administered at dose levels of 2,000, 1,000, 500, 250 and 0 mg/kg body weight. After single oral administration to both sexes of SD rats, the rats were observed for 14 days. In primary skin irritation test, New Zealand white rabbits were dermally treated with Lamia-Kill$^{(R)}$ for 24 hr and observed for 3 days. All rats treated with Lamia-Kill$^{(R)}$ were induced no toxic signs in mortalities, clinical findings, body weights and gross findings. Also, the disinfectant did not induce any adverse reactions such as erythema and edema on intact skin sites for the most part rabbits, but on abraded skin sites, some rabbits showed very slight erythema on 24 hr after topical application. With the results of this study, Lamia-Kill$^{(R)}$ have no effect on acute toxicity and side effect in SD rats and was classified as a practically non-irritating material based on the score 0.50 of primary irritation index.

Status of Constructed Wetlands in Nepal: Recent Developments and Future Concerns (네팔에서의 인공습지 적용: 최근 개발 및 향후 고려사항)

  • Gurung, Sher Bahadur;Geronimo, Franz Kevin F.;Lee, Soyoung;Kim, Lee-Hyung
    • Journal of Wetlands Research
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    • v.19 no.1
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    • pp.45-51
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    • 2017
  • Nepal is a landlocked mountainous country in South Asia, located between China to the north and India to the south, east, and west. As such, wastewater management has become one of the most significant problems in urban area of Nepal. In Nepal, the centralized wastewater treatment systems were dysfunctional due to high cost of operation, discontinuous power supply, lack of proper maintenance and proper technical workforce to address the issues. As such, constructed wetlands (CW) were applied to treat various secondary wastewater as alternative to wastewater treatment facilities. Generally, efficiency and sustainability of CW technology depends on proper operation and maintenance and active community involvement. This study summarizes information about 26 CW in Nepal. Specifically, factors including data banking, removal efficiency, quality of discharged water, compliance to water quality standard of Nepal and operation and maintenance were investigated. Considering removal efficiency per pollutant, Ka-1 achieved the greatest reduction for most pollutant followed by B-1, L-3, Ka-5 and K-1. Nepal has practiced CW technology for more than 2 decades but currently, development of technology was interrupted by the inefficient performance of existing facilities. Public awareness about the technology, natural disaster, unavailability of specified substrate materials, lack of fund for further research and experiments has hindered the expansion of technology. In spite of these concerns, CW was still proven as an alternative solution to the present wastewater problems in urban areas of Nepal.

EU organic policies reflected on EU, Wales and England organic action plans for the development of Korean organic action plan

  • Cho, Youn-Sup;Nicholas, Phillipa;Lampkin, Nicolas;Padel, Susanne
    • Proceedings of the Korean Society of Organic Agriculture Conference
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    • 2009.12a
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    • pp.281-281
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    • 2009
  • Although national and regional environmentally friend agriculture (EFA) and food development programmes such as the Life-Food Development Plan (LFDP) have been established in Korea, some policy measures in these programmes seem to be unsuitable for Korean organic farming development. Policy measures tend to support external input purchases of organic fertilizers rather than market development actions such as providing consumer information, research, education, training and statistical data collection. The development of an organic action plan (OAP) for Korea is therefore considered essential for the sustainable future of organic farming in Korea. The purposes of OAP are 1) to define and set the clear goals/targets for the organic sector development, 2) to integrate various organic stakeholders and public institutions in partnership, 3)to focus on specific issues with tailored measures and 4) to integrate and develop different policy measures (Stolze, 2005). Most EU member state countries have developed their own OAPs and each reflects its own priorities with regard to organic sector development. This study compares and contrasts the Welsh, England and EU OAP with the Korean Jeonnam Life-Food Development Plan (LFDP) in order to facilitate the development of the organic food and farming sector in Korea. Early action plan, for example, the first Welsh OAP(1999) focused support on developing the supply of organic products whereas later action plans (e.g. England OAPs in 2002 and 2004 and the second Welsh OAP in 2005) focussed more on developing consumer demands for organic products. The EU OAP (2004) also aims at market support related to consumer demand and then organic farming production for its environmental and other social benefits. OAPs not only provide specific issue-solving tools but also perform a role as providing a focus for organic sector development as a whole. The Korean LFDP provides issue-solving tools but plays no regulatory role such as policy development, harmonizing various policy measures and conflicting factors and providing evaluation tools for further development. A national-level OAP could also facilitate international trade of organic products. To achieve better harmonized and sustainable approaches for the Korean organic industry, National- as well as regional- regulatory policy systems are urgently required in the form of an Organic Action Plan.

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Anticoccidial Efficacy of Coccimuel-S composed with Diclazuril on Experimental and Field Coccidiosis in Broiler Chickens (Diclazuril을 주성분으로 하는 콕시멸-에스의 육계에 대한 실험실 및 야외적용 실험에서의 항콕시듐 효과)

  • Cha, Chun-Nam;Son, Song-Ee;Kim, Suk;Lee, Yeo-Eun;Yoo, Chang-Yeul;Park, Eun-Kee;Lee, Hu-Jang
    • Journal of Veterinary Clinics
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    • v.29 no.2
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    • pp.154-159
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    • 2012
  • The efficacy of water soluble formulation of diclazuril (Coccimuel-S 0.5%) was tested against $Eimeria$ spp. infection broiler chickens. The experiment was performed both experimentally infection and in the field test. Coccimuel-S composed with diclazuril induced a marked inhibitory effect on the different stages of $Eimeria$ life cycle in experimentally infected broiler chickens treated with the drug. The tested dosage levels of Coccimuel-S (0.5 ml/L, equivalent to diclazuril 2.5 ppm) in drinking water showed the significant effect compared with the control group in controlling coccidial infection and reducing the total oocyst numbers, lesion and fecal scores ($p$ < 0.001). In addition, testing of Coccimuel-S (0.25 and 0.5 ml/L) in naturally infected poultry farms (1,200 broiler chickens), showed the significant anticoccidial effect compared to control ($p$ < 0.001). In conclusion, addition of Coccimuel-S at the dose of 0.25 and 0.5 ml/L in the drinking water, induced efficacious effect for the treatment of coccidiosis in naturally coccidia infected broiler chickens.

A study on Improving Intermodulation Signal of the RF Power Amplifier Using Microwave Absorber (전파흡수체에 의한 전력증폭기의 혼변조 신호의 개선 효과에 관한 연구)

  • Jeon, Joong-Sung;Kim, Min-Jung;Ye, Byeong-Duck;Kim, Dong-Il
    • Journal of Navigation and Port Research
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    • v.27 no.4
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    • pp.437-441
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    • 2003
  • In this paper, the 30 W power amplifier for an IMT-2000 repeater was developed a gain flatness and the third IMD (Intermodulation distortion) by microwave absorber. The absorption ability of the absorber is shown up to -10 dB and -4 dB at 3.6 GHz, 2.3 GHz band, respectively. The power amplifier without absorber has the gain over 57 dB, the gain flatness of $\pm$0.33 dB and the third IMD of 27 dBc at 33.3 W output. Otherwise, the power amplifier with absorber has the gain over 58 dB, the gain flatness of less than $\pm$0.9, the third IMD over 29 dBc at the same output power. As a result, the characteristic of the different type shows improvement of 1 dB in gain, 0.3 dB in gain flatness and 1.77 dBc in IMD.

The Estimation of Groundwater Recharge with Spatial-Temporal Variability at the Musimcheon Catchment (시공간적 변동성을 고려한 무심천 유역의 지하수 함양량 추정)

  • Kim Nam-Won;Chung Il-Moon;Won Yoo-Seung;Lee Jeong-Woo;Lee Byung-Ju
    • Journal of Soil and Groundwater Environment
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    • v.11 no.5
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    • pp.9-19
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    • 2006
  • The accurate estimation of groundwater recharge is important for the proper management of groundwater systems. The widely used techniques of groundwater recharge estimation include water table fluctuation method, baseflow separation method, and annual water balance method. However, these methods can not represent the temporal-spatial variability of recharge resulting from climatic condition, land use, soil storage and hydrogeological heterogeneity because the methods are all based on the lumped concept and local scale problems. Therefore, the objective of this paper is to present an effective method for estimating groundwater recharge with spatial-temporal variability using the SWAT model which can represent the heterogeneity of the watershed. The SWAT model can simulate daily surface runoff, evapotranspiration, soil storage, recharge, and groundwater flow within the watershed. The model was applied to the Musimcheon watershed located in the upstream of Mihocheon watershed. Hydrological components were determined during the period from 2001 to 2004, and the validity of the results was tested by comparing the estimated runoff with the observed runoff at the outlet of the catchment. The results of temporal and spatial variations of groundwater recharge were presented here. This study suggests that variations in recharge can be significantly affected by subbasin slope as well as land use.

In Vitro Antibacterial Effect of the Combination of Galla rhois ethanol extracts and Sodium chlorate against Intramacrophage Brucella abortus

  • Cha, Chun-Nam;Hong, Il-Hwa;Yu, Eun-Ah;Park, Eun-Kee;Yoo, Chang-Yeol;Kim, Suk;Lee, Hu Jang
    • Journal of Food Hygiene and Safety
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    • v.29 no.1
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    • pp.67-72
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    • 2014
  • This study investigated the antibacterial effects of GR ethanol extracts (GRE), sodium chlorate (SC) and a combination of GRE and SC (GS) on Brucella abortus (B. abortus). The antibacterial activities of GRE, SC and GS towards B. abortus were evaluated by incubating B. abortus with GRE, SC and GS. Following treatment with GRE, SC and GS, B. abortus survival and intracellular proliferation in macrophages were monitored. In the cellular cytotoxicity assay, GRE, SC and GS are not cytotoxic at concentrations less than $400{\mu}g/ml$, 15 mM and 0.6GS (1 of GS, GRE $1,000{\mu}g/ml$ + SC 30 mM), respectively. The viability of B. abortus was markedly decreased in a dose-dependent manner in all treatment groups. In addition, B. abortus intracellular proliferation within macrophages was significantly reduced in cells treated with GRE ($400{\mu}g/mL$), SC (15 mM) and 0.5GS (GRE $500{\mu}g/mL$ + SC 15 mM) after 48 hr-incubation (GRE, p < 0.01; SC and 0.5GS, p < 0.001). Especially, in the treatment of GS, the synergistic effect of GRE and SC treatment on B. abortus in macrophage was observed. In conclusion, GS is useful as an antibacterial candidate against B. abortus, and can be applied in the field of meat and milk hygiene.

Improvement of legal systems of automobile in the era of the 4th industrial revolution (4차 산업혁명 시대의 자동차 관련 법제의 합리적 개선방안)

  • Park, Jong-Su
    • Journal of Legislation Research
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    • no.53
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    • pp.269-310
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    • 2017
  • This article aims at the study on Improvement of legal System which is related to automated vehicles in the era of the 4th industrial revolution. Legal aspects of driving automation have two view points. One is to permit a automated vehicle, the other is to regulate the behavior of driver on the road. Signifying elements of the 4th industrial revolution are IoT, AI, big data, cloud computing etc. Automated vehicles are the imbodiment of those new ICT technologies. The vehicle management act(VMA) rules about vehicle registration and approval of vehicle types. VMA defines a automated vehicle as a vehicle which can be self driven without handling of driver or passenger. Vehicle makers can take temporary driving permission for testing and research the driving automation. Current definition of automated vehicle of VMA is not enough for including all levels of SAE driving automation. In the VMA must be made also a new vehicle safty standard for automated vehicle. In the national assembly is curruntly pending three draft bills about legislation of artificial intelligence. Driving automation and AI technologies must be parallel developed. It is highly expected that more proceeding research of driving automation can be realized as soon as possible.

Review of Earthquake Studies Associated with Groundwater by Korean Researchers (국내 연구진의 지하수를 이용한 지진 연구 동향 분석)

  • Yun, Sul-Min;Hamm, Se-Yeong;Cheong, Jae-Yeol;Lee, Hyun A
    • Journal of the Korean earth science society
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    • v.43 no.1
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    • pp.165-175
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    • 2022
  • Earthquakes have occurred owing to movements on a fault since several billion years ago. Research on the relationship between earthquakes and groundwater began in the 1960s in the United States, but related works, including hydrogeochemistry research, only began in the 2010s in South Korea. In this study, domestic studies on the relationship between earthquakes and groundwater until 2021 were collected from the Web of Science and characterized by subject area (groundwater level, hydrogeochemistry, combination of the two, and others). The results showed that the number of published articles per year was positively correlated with the 2011 Tohoku earthquake, 2016 Gyeongju earthquake, and 2017 Pohang earthquake, with the maximum numbers observed in 2011, 2018, 2019, and 2020. Most studies on the relationship between earthquakes and groundwater level addressed groundwater level fluctuations in the duration of the subject earthquake, with little consideration of the precursors. Groundwater level monitoring data, as well as hydrogeochemical information and microbial communities, may contribute to a more detailed understanding of groundwater flow and chemical reactions in bedrock caused by earthquakes. Therefore, the establishment of a national groundwater monitoring network for seismic monitoring and prediction is required.

A Study on the Space Composition for Department of Delivery in Regional Public Hospital (지역거점 공공병원의 분만부 공간구성에 관한 연구(1))

  • Park, Kyeong Hyeon;Shin, Hwa Kyoung;Chai, Choul Gyun
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.28 no.3
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    • pp.47-54
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    • 2022
  • Purpose: This study presents the analysis on space usage of delivery departments in regional public hospitals. The results intention is to achieve improvement of the delivery environment for the mothers and newborns regarding exposure prevention and efficient infection control. The purpose of this study is to provide fundamental data for architectural plans and guidelines for the delivery department. Method: The investigation and analysis were based on research papers, legal systems, public medical statistical data, and the architectural floor plan drawing. For research, 20 regional public hospitals with an operating delivery room were excluded. Regarding data accessibility, 15 regional public hospitals were selected. Results: To overcome the increased vulnerability of the delivery department, the research results of basic data is provided for the establishment to address urgent needs and rapid response. Thus, the research results are as follows: Firstly, the delivery department needs to respond promptly according to the type of patients. For example, in a case of emergency surgery, a connected circulation plan with the related departments is needed. Secondly, for the environment of the delivery area, alleviating anxiety is imperative for pregnant patients and guardians, labor, childbirth, and recovery. Therefore, these needs must be addressed for treatment space and circulation. Lastly, the delivery department is classified into three areas for analysis: access area, treatment area, and support area. In most of the delivery departments of the 15 selected hospitals, there is no space for the access and support area except for the labor and delivery rooms in the treatment area. For the access area, a waiting area, changing room for pregnant women and guardians, and a storage space for contaminated linens are required for infection prevention, safety, and efficiency. For the treatment area, childbirth processes and circulation should have space reserved for labor, delivery, recovery, examination, and treatment. In preparation for an emergency during childbirth, emergency response measures and supporting space needs to be established. For the support area, circulation and rooms are to be designed for medical staff support, activity space, storage and transportation of equipment, and urgent medical treatment. Implications: Along with the low fertility rate and the decrease of medical institutions that operate delivery departments, for the purpose of establishing a public medical service system and a healthy medical environment for mothers and newborns, the researched information demonstrates basic data on space plan of delivery departments in regional public hospitals.