• Title/Summary/Keyword: Reproducibility evaluation

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Reproducibility Assessment of Skin Furrows Measurement using Facial Skin Photographing System (전안촬영시스템을 이용한 주름 측정의 재현성 평가)

  • Lee, Seung-Ryun;Lee, Yun-Kyu;Park, Seo-Young;Ko, Kyoung-Mo;Lee, Yoon-Kyoung;Kim, Jae-Su;Lee, Bong-Hyo;Lim, Seong-Chul;Jung, Tae-Young;Lee, Kyung-Min
    • Journal of Acupuncture Research
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    • v.25 no.1
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    • pp.187-197
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    • 2008
  • Objectives : The purpose of this study was to assess the reproducibility of measurement of facial skin furrows using a facial skin photographing system. Methods : Subjects were 19 patients who visited the department of acupuncture and moxsibustion, at the hospital of Oriental medical college, at Daegu Haany University for the cosmetic acupuncture treatment during August 2007 to 31th August 2007. The facial skin photograph of each participant was analyzed a total of six times in two days using DM-3(a facial skin photographing system). The square and counts of skin furrows were also measured for each one. As the statistical method, Pearson's correlation coefficient and repeated measured ANOVA were used. Results : The Pearson's correlation coefficient, it showed significantly high correlation in both the square and count of skin furrows for each analysis time. Repeated measured ANOVA showed no significant differences among analyses in both square and count of skin furrows. Conclusions : This study reveales that the measurement of the count and square of facial skin furrows by facial skin photograph analysis has high reproducibility. DM-3(a facial skin photographing system) can be useful for the evaluation of facial skin furrows in facial cosmetic acupuncture.

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Comparative analysis on reproducibility among 5 intraoral scanners: sectional analysis according to restoration type and preparation outline form

  • Park, Ji-Man
    • The Journal of Advanced Prosthodontics
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    • v.8 no.5
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    • pp.354-362
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    • 2016
  • PURPOSE. The trueness and precision of acquired images of intraoral digital scanners could be influenced by restoration type, preparation outline form, scanning technology and the application of power. The aim of this study is to perform the comparative evaluation of the 3-dimensional reproducibility of intraoral scanners (IOSs). MATERIALS AND METHODS. The phantom containing five prepared teeth was scanned by the reference scanner (Dental Wings) and 5 test IOSs (E4D dentist, Fastscan, iTero, Trios and Zfx Intrascan). The acquired images of the scanner groups were compared with the image from the reference scanner (trueness) and within each scanner groups (precision). Statistical analysis was performed using independent two-samples t-test and analysis of variance (${\alpha}=.05$). RESULTS. The average deviations of trueness and precision of Fastscan, iTero and Trios were significantly lower than the other scanners. According to the restoration type, significantly higher trueness was observed in crown and inlay than in bridge. However, no significant difference was observed among four sites of preparation outline form. If compared by the characteristics of IOS, high trueness was observed in the group adopting the active triangulation and using powder. However, there was no significant difference between the still image acquisition and video acquisition groups. CONCLUSION. Except for two intraoral scanners, Fastscan, iTero and Trios displayed comparable levels of trueness and precision values in tested phantom model. Difference in trueness was observed depending on the restoration type, the preparation outline form and characteristics of IOS, which should be taken into consideration when the intraoral scanning data are utilized.

Performance Evaluation of the Automated Fluorescent Immunoassay System Rotavirus Assay in Clinical Samples

  • Kim, Jae-Seok;Lee, Su-Kyung;Ko, Dae-Hyun;Hyun, Jungwon;Kim, Hyun Soo
    • Annals of Laboratory Medicine
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    • v.39 no.1
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    • pp.50-57
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    • 2019
  • Background: The Automated Fluorescent Immunoassay System (AFIAS) rotavirus assay (Boditech Med Inc., Chuncheon, Korea) is a new rapid antigen test for rotavirus detection. We evaluated the performance of this assay for detecting rotaviruses and their specific genotypes in clinical stool samples. Methods: AFIAS rotavirus assay was performed in 103 rotavirus-positive and 103 rotavirus-negative stool samples (confirmed by both PCR and ELISA), and its results were compared with those of PCR, ELISA, and immunochromatographic assay (ICA). We evaluated diagnostic sensitivity/specificity, the detectability of rotavirus subtypes, lower limit of detection (LLOD), reproducibility, cross-reactivity, and interference of AFIAS rotavirus assay. Results: Based on PCR and ELISA results, diagnostic sensitivity and specificity of the AFIAS rotavirus assay were both 99.0%. LLOD results showed that the AFIAS assay had sensitivity similar to or greater than ICA and ELISA. High reproducibility was confirmed, and no cross-reactivity or interference was detected. This assay could detect genotypes G1P[8], G2P[4], G3P[8], G4P[6], G4P[8], G8P[4], G8P[8], G9P[4], and G9P[8]. Conclusions: The AFIAS rotavirus assay showed high reproducibility, sensitivity, and specificity as well as excellent agreement with ELISA, PCR, and ICA. It detected the most common as well as unusual genotypes of rotavirus prevalent in Korea. It could be a useful onsite assay for rapid, convenient, and cost-effective detection of rotavirus infection.

Vulnerability Evaluation Methodology for firewall Certification (침입차단시스템 제품 인증을 위한 취약성 평가 방법)

  • 김점구
    • The Journal of Information Technology
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    • v.3 no.3
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    • pp.27-37
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    • 2000
  • Although an insurance criterion for reliance is unified, the difference in evaluation mechanism in every country is already ambiguity. In other words, the aspect of objectivity would be a little because it is true that the vulnerability evaluation include evaluator, scenario and tools (TSVES) applying in test, depth and scope of evaluation. But evaluation results can be difference in accordance with each evaluation elements. By using TSVES to evaluating network security vulnerability, first, we expected the evaluation results is impartiality, objectivity, repeatability, reproducibility, appropriateness and soundness of results. Second, it could be transferred manual ways into automation ways, and then expected easiness and safety of extension and modification in a quality of products as well as a dramatical reduction of waste of time and energy.

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Development and Implementation of Experimental Design Process for Estimating the Measurement Precisions (측정 정밀도 추정을 위한 게이지 실험계획 프로세스 개발 및 적용)

  • Choi, Sung-Woon
    • Proceedings of the Safety Management and Science Conference
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    • 2009.11a
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    • pp.557-563
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    • 2009
  • The research develops measurement processes for estimating and evaluating the gauge R&R(Reproducibility & Repeatability) using ANOVA(Analysis of Variance) of experimental design tools. The ten-step processes developed include experimental goal setting, the selection of characteristics(factors, levels), data model, ANOVA, EMS(Expected Mean Square), estimation of gauge precisions, and evaluation indexes. The three-factor combined measurement models are presented to show the processes developed in this paper.

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Development and Evaluation of Silicon Passive Layer Dosimeter Based Lead-Monoxide for Measuring Skin Dose (피부선량 측정을 위한 Lead-Monoxide 기반의 Silicon Passive layer PbO 선량계 개발 및 평가)

  • Yang, Seung-Woo;Han, Moo-Jae;Jung, Jae-Hoon;Bae, Sang-Il;Moon, Young-Min;Park, Sung-Kwang;Kim, Jin-Young
    • Journal of the Korean Society of Radiology
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    • v.15 no.6
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    • pp.781-788
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    • 2021
  • Due to the high sensitivity to radiation, excessive exposure needs to be prevented by accurately measuring the dose irradiated to the skin during radiation therapy. Although clinical trials use dosimeters such as film, OSLD, TLD, glass dosimeter, etc. to measure skin dose, these dosimeters have difficulty in accurate dosimetry on skin curves. In this study, to solve these problems, we developed a skin dosimeter that can be attached according to human flexion and evaluated its response characteristics. For the manufacture of the dosimeter, lead oxide (PbO) with high atomic number (ZPb: 82, ZO: 8) and density (9.53 g/cm3) and silicon binders that can bend according to human flexion were used. In the case of a dosimeter made of PbO material, the performance degradation has been prevented by using parylene and others due to the presence of degradation due to oxidation, but the previously used parylene is affected by bending, so a new form of passive layer was produced and applied to the skin dosimeter. The characteristic evaluation of the skin dosimeter was evaluated by analyzing SEM, reproducibility, and linearity. Through SEM analysis, bending was evaluated, reproducibility and linearity at 6 MeV energy were evaluated, and applicability was assessed with a skin dosimeter. As a result of observing the dosimeter surface through SEM analysis, the parylene passive layer PbO dosimeter with the positive layer raised to the parylene produced cracks on the surface when bent. On the other hand, no crack was observed in the silicon passive layer PbO dosimeter, which was raised to silicon passive layer. In the reproducibility measurement results, the RSD of the silicon passive layer PbO dosimeter was 1.47% which satisfied the evaluation criteria RSD 1.5% and the linearity evaluation results showed the R2 value of 0.9990, which satisfied the evaluation criteria R2 9990. The silicon passive layer PbO dosimeter was evaluated to be applicable to skin dosimeters by demonstrating high signal stability, precision, and accuracy in reproducibility and linearity, without cracking due to bending.

Reproducibility of Regional Pulse Wave Velocity in Healthy Subjects

  • Im Jae-Joong;Lee, Nak-Bum;Rhee Moo-Yong;Na Sang-Hun;Kim, Young-Kwon;Lee, Myoung-Mook;Cockcroft John R.
    • International Journal of Vascular Biomedical Engineering
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    • v.4 no.2
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    • pp.19-24
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    • 2006
  • Background: Pulse wave velocity (PWV), which is inversely related to the distensibility of an arterial wall, offers a simple and potentially useful approach for an evaluation of cardiovascular diseases. In spite of the clinical importance and widespread use of PWV, there exist no standard either for pulse sensors or for system requirements for accurate pulse wave measurement. Objective of this study was to assess the reproducibility of PWV values using a newly developed PWV measurement system in healthy subjects prior to a large-scale clinical study. Methods: System used for the study was the PP-1000 (Hanbyul Meditech Co., Korea), which provides regional PWV values based on the measurements of electrocardiography (ECG), phonocardiography (PCG), and pulse waves from four different sites of arteries (carotid, femoral, radial, and dorsalis pedis) simultaneously. Seventeen healthy male subjects with a mean age of 33 years (ranges 22 to 52 years) without any cardiovascular disease were participated for the experiment. Two observers (observer A and B) performed two consecutive measurements from the same subject in a random order. For an evaluation of system reproducibility, two analyses (within-observer and between-observer) were performed, and expressed in terms of mean difference ${\pm}2SD$, as described by Bland and Altman plots. Results: Mean and SD of PWVs for aorta, arm, and leg were $7.07{\pm}1.48m/sec,\;8.43{\pm}1.14m/sec,\;and\;8.09{\pm}0.98m/sec$ measured from observer A and $6.76{\pm}1.00m/sec,\;7.97{\pm}0.80m/sec,\;and\;\7.97{\pm}0.72m/sec$ from observer B, respectively. Between-observer differences ($mean{\pm}2SD$) for aorta, arm, and leg were $0.14{\pm\}0.62m/sec,\;0.18{\pm\}0.84m/sec,\;and\;0.07{\pm}0.86m/sec$, and the correlation coefficients were high especially 0.93 for aortic PWV. Within-observer differences ($mean{\pm}2SD$) for aorta, arm, and leg were $0.01{\pm}0.26m/sec,\;0.02{\pm}0.26m/sec,\;and\;0.08{\pm}0.32m/sec$ from observer A and $0.01{\pm}0.24m/sec,\;0.04{\pm}0.28m/sec,\;and\;0.01{\pm}0.20m/sec$ from observer B, respectively. All the measurements showed significantly high correlation coefficients ranges from 0.94 to 0.99. Conclusion: PWV measurement system used for the study offers comfortable and simple operation and provides accurate analysis results with high reproducibility. Since the reproducibility of the measurement is critical for the diagnosis in clinical use, it is necessary to provide an accurate algorithm for the detection of additional features such as flow wave, reflection wave, and dicrotic notch from a pulse waveform. This study will be extended for the comparison of PWV values from patients with various vascular risks for clinical application. Data acquired from the study could be used for the determination of the appropriate sample size for further studies relating various types of arteriosclerosis-related vascular disease.

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Uncertainty Evaluation of Ammonia Determination in Burley Tobacco (버어리종 담배중 암모니아성 질소에 대한 불확도 측정)

  • Lee Jeong-Min;Lee Kyoung-Ku;Han Sang-Bin
    • Journal of the Korean Society of Tobacco Science
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    • v.27 no.1 s.53
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    • pp.107-114
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    • 2005
  • The uncertainty of measurement in quantitative analysis of ammonia by continuous-flow analysis method was evaluated following internationally accepted guidelines. The sources of uncertainty associated with the analysis of ammonia were the weighing of sample, the preparation of extracting solution, the addition of extracting solution into the sample, the reproducibility of analysis and the determination of water content in tobacco, etc. In calculating uncertainties, Type A of uncertainty was evaluated by the statistical analysis of a series of observation, and Type B by the information based on supplier's catalogue and/or certificated of calibration. It was shown that the main source of uncertainty was caused by the volume measurement of 1 mL and 2 mL, the purity of ammonia reference material in the preparation of standard solution, the reproducibility of analysis and the determination of water content of tobacco. The uncertainty in the addition of extraction solution, the sample weighing, the volume measurement of 50 mL and 100 mL, and the calibration curve of standard solution contributed relatively little to the overall uncertainty. The expanded uncertainty of ammonia determination in burley tobacco at $95\%$ level of confidence was $0.00997\%$.

The Evaluation of Usefulness New Assistant Device to Increase Patient Convenience and Processes Efficiency of Radiographic Procedures for Merchant View (Merchant View 촬영 시 환자 편의와 업무 효율성 증대를 위한 새로운 촬영 보조기구 개발 및 유용성 평가)

  • Son, Sang-Hyuk;Kim, Sung-Kyu
    • Korean Journal of Digital Imaging in Medicine
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    • v.12 no.1
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    • pp.43-50
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    • 2010
  • The representative study of Patellofemoral Joint Merchant method can show the view for inspection of the sulcus angle, congruence angle and diagnose whether there are the vertical fractures and recognize the degree of dislocation and patella subluxation. However, anatomical correlation about the degree of knee joint curvature changes during position adjustment and distortion of the image reduces reproducibility. In order to resolve these problems, Merchant method needs to use assisting device which reduces the occurrence of repeat projection and effectively to increase unification of examination and the consistency of the image. However, there are disadvantages for patients who take other examinations. For example, they have to change the position for every examination and it might cause the patient's discomfort and increase of examination time. In this study, we newly devised commercial assisting device which improves the reproducibility of the images and reduces inconvenience of patients movement. Further research should be taken to obtain a image without patient's movement and to reduce the time of the examination than existing method.

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