• Environmental and Resource Economics Review
• /
• v.24 no.2
• /
• pp.343-363
• /
• 2015

This study is to analyze the effects of climate change on national total factor productivity. Changes in temperature and rainfalls which are the representative climate variables are used as main factors to measure climate change. Not only average values of the variables but those highest values are used as independent variables in the model, in order to consider the characteristic pattern of recent climate change, the high volatilities. The OLS results are corresponding to previous literature that average temperature has a negative relationship with productivities while average rainfalls have a positive relationship. However, the results of panel analysis contradict the argument of the negative relationship between average temperature and productivities since human beings can adapt the climate change. Therefore adaptation capacity is important to forecast the effects of climate changes on economies.

• Journal of the Korean housing association
• /
• v.21 no.5
• /
• pp.103-113
• /
• 2010

The post-war period has witnessed the emergence of new towns in a number of countries in Southeast Asia. The new town development in Malaysia started with Petaling Jaya (PJ) as a satellite town in 1953 to accommodate the rapid growing population of Kuala Lumpur (KL). Shah Alam (SA), Subang Jaya (SJ) are all located in the Klang Valley and act as an important social and economic development hub in the nation. New towns have been designed in accordance with the British town planning principles, which were based on the model of a modern ideal city. They constituted a new regional character because they were developed taking into consideration factors such as local technologies as well as site and, climatic conditions. The initial goal of the new town construction and planning, which focused basically on resettling squatters, was later changed to focus on the improvement of the quality of living. This phenomenon was related to the emergence of the middle class, which had grown rapidly ever since. With the public agencies, the private sectors have played an important role in providing viable and sustainable human units of settlement that address the new design issues of new town planning. The goal of this study is to identify the identity of the recent new town planning principles of Malaysia, how they were developed over time and how they were regionalized and transformed in a cultural and regional context. For the analysis, we chose 3 new towns which are located in Klang Valley and which are representative recent projects of two major housing development companies in Malaysia. To identify the planning principles, we analyzed these projects in the viewpoint of the urban space, street system, and housing blocks and units.

• The KIPS Transactions:PartB
• /
• v.18B no.2
• /
• pp.67-72
• /
• 2011

Single nucleotide polymorphisms (SNPs) are a very important tool for the study of human genome structure. Cluster analysis of the large amount of gene expression data is useful for identifying biologically relevant groups of genes and for generating networks of gene-gene interactions. In this paper we compared the clusters of SNPs within asthma group and normal control group obtained by using hierarchical cluster analysis method with entropy distance. It appears that the 5-cluster collections of the two groups are significantly different. We searched the best set of SNPs that are useful for diagnosing the two types of asthma using representative SNPs of the clusters of the asthma group. Here support vector machines are used to evaluate the prediction accuracy of the selected combinations. The best combination model turns out to be the five-locus SNPs including one on the gene ALOX12 and their accuracy in predicting aspirin tolerant asthma disease risk among asthmatic patients is 66.41%.

• Development and Reproduction
• /
• v.14 no.4
• /
• pp.215-223
• /
• 2010

The construction of transgenic mouse using embryonic stem (ES) cells has been crucial in the functional studies of gene on mouse genome. Gene knockout mice have been powerful for elucidating the function of genes as well as a research model for human diseases. Gene targeting and gene trapping mathods have been the representative technologies for making the knockout mice by using ES cells. Since the gene targeting and the gene trapping methods were independently developed about 20 years ago, it's efficiency and productivity has been improved with a advance of molecular biology. Conventional gene targeting method has been changes to high throughput conditional gene targeting. The combination of the advantage of gene targeting and gene tapping elements allows to extend a spectrum of gene trapping and to improve the efficiency of gene targeting. These advance should be able to produce the mutant with various phenotype to target a certain gene, and in postgenome era they have served as crucial research tools in understanding the functional study of whole genome in mouse.

• Journal of KIISE:Computing Practices and Letters
• /
• v.14 no.9
• /
• pp.906-910
• /
• 2008

As the mobile environment becomes widely used, there is a growth on the concern about recognizing and sharing user context. Sharing context makes the interaction between human more plentiful as well as helps to keep a good social relationship. Recently, it has been applied to some messengers or mobile applications with sharing simple contexts, but it is still required to recognize and share more complex and diverse contexts. In this paper, we propose a context-aware messenger that collects various sensory information, recognizes representative user contexts such as emotion, stress, and activity by using dynamic Bayesian networks, and visualizes them. It includes a modular model that is effective to recognize various contexts and displays them in the form of icons. We have verified the proposed method with the scenario evaluation and usability test.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.7
• /
• pp.3043-3050
• /
• 2015

The tumor microenvironment (TME) includes numerous non-neoplastic cells such as leukocytes and fibroblasts that surround the neoplasm and influence its growth. Tumor-associated macrophages (TAMs) and cancerassociated fibroblasts (CAFs) are documented as key players in facilitating cancer appearance and progression. Alteration of the macrophage (CD68, CD163) and fibroblast (${\alpha}-SMA$, FSP-1) cells in Opisthorchis viverrini (Ov) -induced cholangiocarcinoma (CCA) was here assessed using liver tissues from an established hamster model and from 43 human cases using immunohistochemistry. We further investigated whether M2-activated TAMs influence CCA cell migration ability by wound healing assay and Western blot analysis. Macrophages and fibroblasts change their phenotypes to M2-TAMs (CD68+, CD163+) and CAFs (${\alpha}-SMA+$, FSP-1+), respectively in the early stages of carcinogenesis. Interestingly, a high density of the M2-TAMs CCA in patients is significantly associated with the presence of extrahepatic metastases (p=0.021). Similarly, CD163+ CCA cells are correlated with metastases (p=0.002), and they may be representative of an epithelial-to-mesenchymal transition (EMT) with increased metastatic activity. We further showed that M2-TAM conditioned medium can induce CCA cell migration as well as increase N-cadherin expression (mesenchymal marker). The present work revealed that significant TME changes occur at an early stage of Ov-induced carcinogenesis and that M2-TAMs are key factors contributing to CCA metastasis, possibly via EMT processes.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.34 no.7
• /
• pp.1184-1196
• /
• 2010

Several applications of body scanning technology have been commercialized or are currently under development. The virtual fit from 3D scans is most advanced form of virtual try-on. This article is an analysis of the comparison of user preferences for domestic versus foreign 3D virtual try-on systems. For this study, domestic i-Fashion Mall (www.ifashionmall.co.kr) and a Canadian company, My Virtual Model (www.mvm.com) were selected as the most representative online retailers that offer a virtual try-on system. The respondents were comprised of 70 Korean female college students in the age group 20-29. A five point Likert scale was used to evaluate the degree of the preference of virtual avatar and try-on images. T-test, cross table, and a chi-square independence test were conducted for data analysis. The results are as follow. 1. The representation about current looks according to each virtual fit image indicates that MVM is more accurate than i-Fashion Mall. 2. About decision confidence, respondents have decision confidence in i-Fashion Mall in the case of the avatar image; however, respondents have confidence in MVM or the fit image. 3. There were no significant differences in among waist size groups in accuracy, trust of each avatar image, while there were significant differences among waist size groups in the accuracy and trust of each virtual fit image. 4. About ease of use, respondents answered that i-Fashion Mall is superior to MVM. 5. The respondents prioritized the ‘fitting report’ of i-Fashion Mall and ‘Weight loss’ of MVM over other functionalities.

• Journal of Environmental Impact Assessment
• /
• v.8 no.3
• /
• pp.1-11
• /
• 1999

This study was carried out to evaluate urban environmental structure in Taegu metropolitan region(TMR) with factor analysis, fuzzy set theory, geostatistic and geographic information system(GIS). The factor analysis could choose the representative one out of multiple variables and simplify the evaluation of the urban environmental structure. The fuzzy approach is an attempt to model an aspect of human thinking previously neglected; it starts from the premise that humans don't represent classes of objects as fully disjoint but rather as sets where transitions from membership to non-membership is gradual. The Geographic Information System(GIS) could connect attributes of factor scores derived from factor analysis to digital map by a method so called 'Spatial join'. The results obtained were as follows: Urbanization appearance was concentrated in the large cities, and this appearance was partial extremely, therefore, there has been a structural gap between urban area and agricultural area which was unified into the urban area. All inclinations didn't become worse after sudden urbanization. For example, suburban agriculture was developed as a large scale in the region near the large cities. Then it encouraged farmers in changing their old cultivating methods to the latest ones. But many districts in urban fringe had symptom of urbanization, the districts which were located between large cities have been developed gradually because of urban sprawl, and played a role in connecting each city. Therefore, due to the urbanization, forestry area and agricultural land, well conserved in the agricultural town, could be easily destroyed. In a different way with the urbanization of the Seoul metropolitan region, that of TMR was centralized upon the center of each city, and it was also very partial. But, because so many regions have the potentiality of urbanization, hereafter, the urbanization process in each region is likely to be different multifariously according to the urban management methods.

• The Korean Journal of Health Service Management
• /
• v.3 no.2
• /
• pp.65-75
• /
• 2009

This study aims at deriving any useful information necessary to strengthen the competitiveness for growth through empirical analyses on a general hospital located in a province in order to countermeasure the opening and competition of medical markets. The characteristics of user were identified on the basis of disease groups under KCD in the research method. In addition, the analysis on the expenses of diagnosis and treatment was divided into the treatment progress and degree of hospital resource utilization. And the regression was carried out to identify the impacts of characteristics of inpatient users on the degree of hospital resource utilization. As a result of major research, the inpatient users of the general hospital located in the provincial area in consideration of inpatient users were formed around the inpatient disease groups representative for Korea. And it was understood that most of residents within a distance of 40 minute by the public transportation were using. Although there are restrictions that the analyses were carried out for a general hospital in a province, the findings of this study can be considered a generalized model for the management of provincial general hospitals when we consider the current circumstance that the diagnosis and treatment are carried out by provincial medical institutions primarily for patients in general within the province, along with implications that any general hospital in Korea should be equipped with the facilities, equipments and human resources under the Medical Treatment Act.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.38C no.2
• /
• pp.165-171
• /
• 2013

WAVE(Wireless Access in Vehicular Environments) is a representative V2V communication protocol and its standards of MAC and PHY parts except for security were published. In order to control traffic flow and ensure driver's safety using V2V communication, various projects are conducting. In particular, safety application has been researched. Therefore, in this paper, we designed the safety application algorithm, which informs a driver of the dangerous status when driver tries to turn left in an intersection and we also implemented the algorithm. Proposed algorithm configures a model for a host vehicle and a vehicle coming in opposite lane and in case that there is collision hazard it provides warning message to driver by using HMI. In order to evaluate the proposed algorithm's performance, we configured the test bed using test vehicles and we tested the algorithm on proving ground with the composed test scenarios. As test results, our system showed excellent performance. If the infrastructures for V2I communications are constructed, we will optimize our system more precisely and stably.