• Title/Summary/Keyword: Replacement method

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Evaluation of Phototoxicity for Cosmetics and Alternative Method (화장품 광독성 평가와 동물대체시험법)

  • Lee, Jong-Kwon;Sin, Ji-Soon;Kim, Jin-Ho;Eom, Jun-Ho;Kim, Hyung-Soo;Park, Kui-Lea
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.3 s.52
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    • pp.245-251
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    • 2005
  • Safety is one of the key issue in the regulation of cosmetics. Cosmetic Act deals with it in Korea. The guidance for the testing cosmetic ingredients and their safety evaluation are prepared by Korea Food and Drug Administration. Ultraviolet radiation could Induce skin damage, edema, erythema, photoaging, immune dysfunction and skin cancer. Ultraviolet radiation is classified as Group 2A(probably carcinogenic to humans) by International Agenry for Reaserch on Cancer(IARC). The in vitro methodologies for evaluating the toxic potential of ingredients reported in the literature have not yet been sufficiently validated for use in areas other than the study for mutagenicity/genotoxicity, for pre-screening for severe irritancy, for screening of phototoxicity and for evaluating the percutaneous absorption. The 3T3 neutral red uptake photoxicity test (3T3 NRU PT) was accepted as OECD toxicity guideline in 2002. The 3T3 NRU PT is an in vitro method based on a comparison of the cytotoxicitv of a chemical when tested in the presence and in the absence of exposure to a non-cytotoxic dose of UVA/visible light.

A New Integrative Approach to Geography Education in the Social Studies Subject - with respect to Replacement of Geographical Contents in the Elementary-leveled Learning - (지리 교과의 통합교육적 접근방안 - 초등 사회과 학습 내용 조직을 중심으로 -)

  • Kang, Kyoung-Won
    • Journal of the Korean association of regional geographers
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    • v.7 no.1
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    • pp.51-66
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    • 2001
  • The curriculum of integrated social studies is not conceptually established, but various forms pursuing so-called perfect integrated subject have appeared from elementary school to high school. But we cannot find out desirable integration in the elementary school though the apparent goal is to integrate all kinds of social concepts into one unit. The current method of integration has some problems over advantages people initially expected by integration. It is problematic in that students learn fragmental knowledges of geography without capturing the whole geographical concept structure or obtaining their own geographical viewpoint. Therefore, we purpose to reinterpret integration of social studies and reorganize the current textbook into the right direction under the assumption that simple mixture of knowledges is far from our goal of true integration. For this purpose, we suggest a new method for social studies as an integrated subject. Instead of providing knowledges unrelated to each other into one bundle, it helps students to see the real world in his own knowledge framework equipped with geographical viewpoint. The text we claim will show students that geography consists of three key concepts: physical environment, man and environment, and spatial structure. With this text, they will have an easy access to the relationships between key concepts and details, and between geographical concepts and similar concepts from other disciplines. The proposal contributes to both upcoming textbook development and classroom teaching by eliminating problems in the current social studies teaching.

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Effect of Sea Water on Curing and Strength of Cemented Sand (해수가 고결모래의 양생 및 강도에 미치는 영향)

  • Park, Sung-Sik;Lee, Jun-Woo
    • Journal of the Korean Geotechnical Society
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    • v.28 no.6
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    • pp.71-79
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    • 2012
  • Sand compaction pile and stone column replacement methods have been commonly used for improving soft ground in the nearshore. Recently, DCM (Deep cement mixing) method, which can harden soft clays by mixing with cement, is more popularly used in such soft ground improvement. Sandy soils also exist in the seashore. Therefore, in this study, the effect of salinity in sea water and curing methods on the strength of cemented sand was evaluated in terms of unconfined compressive strength (UCS). The sand was mixed with five different cement ratios and distilled water or sea water, and then compacted into a cylindrical specimen. They were cured for 3 days under sea water for DCM construction condition and air cured for onshore curing condition. When a specimen was cured under sea water without confinement, it was easily collapsed due to initiation of cracks. When the cement ratio and curing method were the same, the UCS of the specimen without sea water was at maximum 3.5 times higher than those with sea water. The sea water used for mixing sand had more influence on strength reduction than the sea water used for curing. When the cement ratio was the same, the UCS of air-cured specimen was at average 2 times higher than those of water-cured specimen, regardless of water used.

A Performance Improvement of Linux TCP Networking by Data Structure Reuse (자료 구조 재사용을 이용한 리눅스 TCP 네트워킹 성능 개선)

  • Kim, Seokkoo;Chung, Kyusik
    • KIPS Transactions on Computer and Communication Systems
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    • v.3 no.8
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    • pp.261-270
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    • 2014
  • As Internet traffic increases recently, much effort has been put on improving the performance of a web server. In addition to hardware side solutions such as replacement by high-end hardware or expansion of the number of servers, there are software side solutions to improve performance. Recent studies on these software side solutions have been actively performed. In this paper, we identify performance degradation problems occurring in a conventional TCP networking reception process and propose a way to solve them. We improve performance by combining three kinds of existing methods for Linux Networking Performance Improvement and two kinds of newly proposed methods in this paper. The three existing methods include 1) an allocation method of a packet flow to a core in a multi-core environment, 2) ITR(Interrupt Throttle Rate) method to control excessive interrupt requests, and 3) sk_buff data structure recycling. The two newly proposed methods are fd data structure recycling and epoll_event data structure recycling. Through experiments in a web server environment, we verify the effect of our two proposed methods and its combination with the three existing methods for performance improvement, respectively. We use three kinds of web servers: a simple web server, Lighttpd generally used in Linux, and Apache. In a simple web server environment, fd data structure recycling and epoll_event data structure recycling bring out performance improvement by about 7 % and 6%, respectively. If they are combined with the three existing methods, performance is improved by up to 40% in total. In a Lighttpd and an Apache web server environment, the combination of five methods brings out performance improvement by up to 36% and 20% in total, respectively.

Ischial Pressure Sore Reconstruction Using Inferior Gluteal Artery Perforator Flap (아래볼기동맥 관통가지피판을 이용한 궁둥 욕창의 치료)

  • Kim, Young Seok;Kang, Jong Wha;Lee, Won Jai;Tark, Kwan Chul
    • Archives of Plastic Surgery
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    • v.34 no.2
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    • pp.209-216
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    • 2007
  • Purpose: The ischial area is by far the most common site of pressure sores found in wheel chair bound paraplegic patients, because greatest pressure is exerted from the body on this area in a sitting position. Even after a series of successful pressure sore treatments, the site is very prone to relapse by the simplest ordinary tasks of everyday life. Therefore, it is crucial to preserve the main pedicle during primary surgery. Various surgical procedures employed to treat pressure sores such as myocutaneous flap and perforator flap have been introduced. After introduction of ischial sore treatment using the inferior gluteal artery perforator (IGAP) has been made, the authors experienced favorable clinical results of patients who have undergone IGAP flap procedure in a three year time period. Methods: A total of 17 patients received IGAP flap surgery in our hospital from January 2003 to May 2006, among which 14 of them being males and 3 females. Surgery was performed on the same site again in 6(35%) patients who had originally relapsed after receiving the conventional method of pressure sore surgery. Patients' average age was 49.4(27-71) years old. Most of the patients were paraplegic(11 cases, 65%) and others were either quadriplegic(4 cases, 23%) or ambulatory(2 cases, 12%). Based on hospital records and clinical photographs, we have attempted to assess the feasibility and practicability of the IGAP flap procedure through comparative analysis of several parameters: size of defective area, treatment modalities, occurrence of relapses, complications, and postoperative treatments. Results: The average follow-up duration of 17 subjects was 25.4 months(5-42 months). All flaps survived without any necrosis. Six cases were relapsed cases from conventional surgical procedures. All of them healed well during our follow-up study. Postoperative complications such as wound dehiscence and fistula developed in some subjects, but all were well healed through secondary treatment. A total of 2 cases relapsed after surgery. Conclusion: The inferior gluteal artery perforator flap is an effective method that can be primarily applied in replacement to the conventional ischial pressure sore reconstructive surgery owing to its many advantages: ability to preserve peripheral muscle tissue, numerous possible flap designs, relatively good durability, and the low donor site morbidity rate.

A Study on Economic Evaluation Modeling of MVDC Distribution System for Hosting Capacity of PV System (태양광전원 수용을 위한 MVDC 배전망의 경제성평가 모델링에 관한 연구)

  • Lee, Hu-Dong;Kim, Ki-Young;Kim, Mi-Sung;Rho, Dae-Seok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.3
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    • pp.1-12
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    • 2021
  • Technologies for an MVDC(medium voltage direct current) distribution system are being considered as an effective alternative to overcome the interconnection delay issues of PV systems. However, the implementation of a DC distribution system might lead to economic problems because of the development of DC devices. Therefore, this paper deals with the scale of a PV plant based on its capacity and proposes hosting-capacity models for PV systems to establish a network to evaluate the feasibility of an MVDC distribution system. The proposed models can be classified as AC and DC distribution systems by the power-supply method. PV systems with hundreds of MW, dozens of MW, and a few MW can be categorized as large-scale, medium-scale, and small-scale models, respectively. This paper also performed modeling for an economic evaluation of MVDC distribution system by considering both the cost of AC and DC network construction, converter replacement, operation, etc. The profit was composed of the SMP and REC rate of a PV plant. A simulation for economic evaluation was done for the MVDC distribution system using the present worth and equal-principal costs repayment method. The results confirmed that the proposed model is a useful tool to evaluate economic issues of a DC distribution system.

Correction of Aircraft Empty Weight CG due to LRU Modification (구성품 변경에 따른 항공기 공허중량 무게중심 수정 및 검증)

  • Lee, Jin-Won;Kwon, Na-Eun;Kim, Ji-Hong;Park, Jae Hyun
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.50 no.8
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    • pp.551-557
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    • 2022
  • LRU (Line Replacement Unit) modifications are often required for military aircraft due to aging. Recently, LRU modifications were proceeded for KA-O (Armed Airborne Controller) by replacing the ejection seat and adding avionic equipment, which made the aircraft's operational CG (Center of Gravity) on fuel consumption curve become out of the range of the specification requested. The off-ranged CG should be corrected by introducing an appropriate method. This study proposes a procedure for revising and verifying the empty weight CG altered due to LRU modification for small military aircraft (e.g., KA-O). In the proposed method, first, the change of empty weight CG of KA-O due to the LRU modifications is comprehensively examined. Then, several ballast masses are added to the engine mount strut to restore the empty weight CG on the fuel consumption curve to a safe operational range. The installations are verified via stress and fatigue analysis for various operating conditions. Considering that open information is not very available for the revision of empty weight CG, this study is valuable because it presents an established procedure for correcting and verifying empty weight CG during aircraft modification.

Relationships among Nursing Students' Anxiety, Communication Skills, and Nursing Professionalism about On-campus Clinical Practice due to COVID-19 (코로나 19로 인한 간호대학생의 교내임상실습 불안, 의사소통능력 및 간호전문직관간의 관계)

  • Kim, Do-Hui;Lee, Won-Jin;Kang, Min-Ji;Kang, Jee-Yeon;Kim, Na-Rae;Kim, Seo-Yeong;Kim, Seong-A;Park, Seong-Eun;Bae, Sun-Mi
    • Journal of Industrial Convergence
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    • v.20 no.10
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    • pp.9-16
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    • 2022
  • This study was attempted to confirm the correlation between anxiety, communication skills, and nursing professionalism due to the replacement on-campus practice of nursing students due to the COVID-19 outbreak. The subjects of this study were 131 nursing students in 3rd and 4th grade, and data were collected from October 30, 2021 to November 23, 2021. The collected data were analyzed with SPSS Statistics 28.0 using descriptive statistics, t-test, ANOVA, and Person's correlation. As a result of the study, it was found that there was a negative correlation between anxiety and nursing professionalism(r=-.332, p<.001), and there was a positive correlation between communication ability and nursing professionalism (r=.364, p=.000) Based on this study, it is necessary to develop and apply an effective clinical practice education intervention method that can reduce anxiety caused by on-campus practice to enhance nursing professionalism and enhance communication ability. Based on this study, it is necessary to understand the relationship between grade level and nursing professionalism, and to develop and apply an effective anxiety intervention method that can increase nursing professionalism by reducing anxiety caused by on-campus practice.

Characteristics of Flexuarl-Shear Behavior of Beam Using Demonstrated CFRP Rod (국내 시범 생산 CFRP rod를 적용한 보 부재의 휨-전단 특성)

  • Choi, So-Yoeng;Kim, Il-Sun;Choi, Myoung-Sung;Yang, Eun-Ik
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.5
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    • pp.86-94
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    • 2022
  • Replacement of FRP rod as steel reinforcement has been attracted significantly to prevent the degradation of the concrete structure due to corrosion. So, the technology development to extend the structure's service life by improving FRP properties has been proceeded worldwide. Accordingly, it is necessary to develop Korea's CFRP rod and CFRP grid, including the manufacturing techniques to improve the properties of high-strength and high-stiffness. Moreover, the research should be conducted to evaluate the structural behavior of the beams using the CFRP rod or grid. This study investigates the flexural and shear behavior of reinforced concrete beam using demonstrated CFRP rod as reinforcement according to the reinforcement ratio and shear span to depth ratio. From the results, when the reinforcement ratio is out of a specific range, it is seemed that the effect on performance improvement of the beam using CFRP rod is cancelled or not significant. Meanwhile, when the CFRP rod was used as reinforcement, the possibility of shear failure occurred, even steel stirrups were installed in the beam with CFRP rod as tensile reinforcement according to the Korean Design Standard. Therefore, when the CFRP rod is used as tensile reinforcement in a beam, it should be prepared that a specific limitation of reinforcement ratio and an investigation against shear failure. Also, the ductility of the beam using the CFRP rod is determined by the deformation energy evaluation method. So, the ductility should be investigated by applying the deformation energy evaluation method that reflects the structural behavior of the beam.

A Study on the Suitability Analysis of Welding Robot System for Replacement of Manual Welding in Ship Manufacturing Process (선박 제조 공정 분야에서 수용접 대체를 위한 용접 로봇 시스템 도입의 적합성 분석 연구)

  • Kwon, Yong-Seop;Park, Chang-Hyung;Park, Sang-Hyun;Lee, Jeong-Jae;Lee, Jae-Youl
    • Journal of the Korean Society of Industry Convergence
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    • v.25 no.5
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    • pp.799-810
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    • 2022
  • Welding work is a production work method widely used throughout the industry, and various types of welding technologies exist. In addition, many methods are being studied to automate these welding operations using robots, but in the ship manufacturing field, welding such as painting, cutting, and grinding is also the most common operation, but the manual operation ratio is higher than in other industries. Such a high manual labor ratio in the field of ship manufacturing not only causes quality problems and production delays according to the skill of workers, but also causes problems in the supply and demand of manpower. Therefore, this paper analyzed the reason why the automation rate is low in welding work at ship manufacturing sites compared to other industries, and analyzed the production process and field environment for small and medium-sized ship manufacturing companies that repeatedly manufactured with a small quantity production method. Based on the analysis results, it is intended to propose a robot system that can easily move between workplaces and secure uniform welding quality and productivity by collaborating simple welding tasks with humans. Finally, the simulation environment is constructed and analyzed to secure the suitability of robot system application to current production site environment, work process, and productivity, rather than to develop and apply the proposed robot system. Through such pre-simulation and robot system suitability analysis, it is expected to reduce trial and error that may occur in actual field installation and operation, and to improve the possibility of robot application and positive perception of robot system at ship manufacturing sites.