• The Journal of Information Systems
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• v.31 no.4
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• pp.161-187
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• 2022

Purpose This study analyzed the topic of game review contents and how the characteristics of game reviews affect the reviews helpfulness. In addition, this study explore the content of game reviews according to the game's sales strategy such as early access strategy and releasing without early access. Design/methodology/approach We collected a list of 3,572 action genre games released in 2020. 58,336 online reviews were collected by random sampling 50 reviews in each games, and topic modeling was performed on those reviews. We dynamized the results of topic modeling and analyzed the effect on review helpfulness with multiple regression analysis. Findings The results of analysis indicate that the longer the review is or the shorter the time it is written, the more helpful the review is. In addition the topic with positive and negative review has a significant effect on the review helpfulness. As a result of exploratory analysis, games from early access had relatively fewer reviews of story-related topics than games that were released without early access. These findings can present direct guidelines for collecting specific opinions from customers in the game industry when releasing games.

• Journal of the Korean Operations Research and Management Science Society
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• v.39 no.4
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• pp.1-17
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• 2014

The functions of stocking and releasing in logistics center consist of three major procedure such as receiving, shipping and stock managements. Each process includes various sub-processes which are complicatedly connected with each other. Furthermore, lots of operators execute various tasks in the different sub-processes, simultaneously. It makes difficult to standardize, monitor, and analyze the processes. This paper proposed the quantitative methodology using process mining approach to discover and analyze receiving and shipping processes. For this purpose, the PDA operation log data is analyzed to build a realistic process model. The deduced model has been compared with official process model. In addition, task assignment and social networks analysises are carried out by utilizing process mining tools. Also, it has been proposed how to improve the processes with the analytical simulation model based on the results of process mining.

• Journal of Integrative Natural Science
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• v.8 no.3
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• pp.176-183
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• 2015

Corticotropin-releasing actor receptors (CRFRs) activates the hypothalamic pituitary adrenal axis, one of the 2 parts of the fight or flight response to stress. Increased CRH production has is associated with Alzheimer's disease and major depression and hypoglycemia. In this study, we report the important structural and chemical parameters for CRFR inhibitors using the derivatives of 8-substituted-2-aryl-5-alkylaminoquinolines. A 3D QSAR study, Comparative molecular field analysis (CoMFA) was performed. The best predictions were obtained for the best CoMFA model with a $q^2$ of 0.607 with 6 components and $r^2$ of 0.991. The statistical parameters from the generated CoMFA models indicated that the data are well fitted and have high predictive ability. The contour map resulted from the CoMFA models might be helpful in the future designing of novel and more potent CRFR derivatives.

• Natural Product Sciences
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• v.20 no.4
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• pp.281-284
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• 2014

In this study, twenty-one oleanane-type triterpenoid saponins were isolated from a methanol extract of the roots of Pulsatilla koreana. Antagonistic activities were measured in these compounds by the aequorin based cellular functional assay system for the corticotropin releasing factor receptor (CRF1). Of them, compounds 7 - 10 showed the highest degree of CRF1 inhibition further at the concentration of $10{\mu}M$. Moreover, by the analysis based on the structure-activity relationship of isolated saponins, a sugar chain at C-3 and a carboxyl group at C-28, as well as a methyl group at C-23 seems to be key functional elements. To our knowledge, this is the first report on CRF1 inhibition of saponins from P. koreana.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.27 no.7
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• pp.867-876
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• 2003

The Lagrangian dispersion of fluid particles in inhomogeneous turbulence is investigated by a direct numerical simulation of turbulent channel flow. Four points Hermite interpolation in the homogeneous direction and Chebyshev polynomials in the inhomogeneous direction is adopted to simulate the fluid particle dispersion. An inhomogeneity of Lagrangian statistics in turbulent boundary layer is investigated by releasing many particles at several different wall-normal locations and tracking those particles. The fluid particle dispersions and Lagrangian structure functions of velocity are scaled by the Kolmogorov similarity. The auto-correlations of velocity and acceleration are shown at the different releasing locations. Effect of initial particle location on the dispersion is analyzed by the probability density function at the several downstreams and time instants.

• Transactions of Materials Processing
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• v.21 no.4
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• pp.246-251
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• 2012

The mechanism for mechano-luminescence(ML) in SAO phosphor was investigated quantitatively by measuring the emission intensity under three different tensile conditions. It was found that the ML of SAO was strongly dependent on the dynamic loading rate rather than by the applied load itself. The mechano-luminescent emission in SAO was evaluated based on the trap-releasing process. It was found that the shape of the ML curve in the transient regime obtained from the rate equation has good agreement with the experimental data.

• Development and Reproduction
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• v.2 no.2
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• pp.189-196
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• 1998

Several lines of evidence indicate that some neuropeptides classically associated hypothalamus have been found in pituitary gland, suggesting the existence of local regulation of pituitary function. Among the hypothalamic releasing hormones, genes for TRH and GnRH are expressed in the rat anterior pituitary gland. The present study was carried out to investigate the expression of the GHRH gene in rat anterior pituitary and the pituitary-derived cell lines. The presence of GHRH transcripts in pituitary tissue was shown by 3'rapid amplification of cDNA end (3'-RACE) analysis. In reverse transcription-polymerase chain reaction (RT-PCR) study, GHRH cDNA fragments were amplified from two pituitary-derived cell lines, $\alpha$T3 cells originated from mouse gonadotrope and GH3 cells from rat somatolactotrope. Immunoreactive GHRH was detected in large and medium-sized pituitary cells by immunocytochemistry. Significant amounts of GHRH-like molecules were found in the GH3 cell extracts. In RNase protection assay, the level of pituitary GHRH mRNA was augmented by ovariectomy. These results demonstrate that GHRH gene is expressed in the rat gonadotropes and somatotropes, and suggest that the pituitary GHRH could be participated in the paracrine and/or autocrine regulation of cell proliferation, as well as promoting growth hormone secretion.

• Herbal Formula Science
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• v.26 no.4
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• pp.363-380
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• 2018

Objectives : We analyzed the principle of compatibility of socheongnyong-tang and expanded the range of application in clinical practice. Methods : Socheongnyong-tang was analyzed by the compatibility principle through the system of chief, deputy, assistant, and envoy, but the basic formulas of "Discussion of Cold Damage" and "Synopsis of the Golden Chamber" was used. Results : Socheongnyong-tang treats exterior wind-cold and interior water accumulation. Exterior wind-cold is treated mainly by exterior-releasing herbs constituting mahwang-tang and gyeji-tang in "Discussion of Cold Damage", and interior water accumulation is treated mainly by retained fluid-resolving herbs constituting yeonggamomigangsinha-tang, yeonggamomigagangsinbanhahaengin-tang and yeonggamomigagangsinbanhaengdaehwang-tang in "Synopsis of the Golden Chamber". Depending on the weight of exterior wind-cold and interior water accumulation, the disease condition is classified as a case where exterior wind-cold is heavier than interior water accumulation, a case where exterior wind-cold is lighter than interior water accumulation, and a case where it is equivalent. When exterior wind-cold is heavier than interior water accumulation, chief herbs are Ephedrae Herba and Cinnamomi Ramulus of exterior-releasing herbs series and deputy herbs are Zingiberis Rhizoma and Asari Radix et Rhizoma of retained fluid-resolving herbs series. When exterior wind-cold is equal to the disease condition of interior water accumulation, chief herbs are Ephedrae Herba of exterior-releasing herbs series and Zingiberis Rhizoma of retained fluid-resolving herbs series, and deputy herbs are Cinnamomi Ramulus of the exterior-releasing herbs series and Asari Radix et Rhizoma of retained fluid-resolving herbs series. When exterior wind-cold is lighter than interior water accumulation, chief herbs are Zingiberis Rhizoma and Asari Radix et Rhizoma of retained fluid-resolving herbs series and deputy herbs are Ephedrae Herba and Cinnamomi Ramulus of exterior-releasing herbs series. In any case, assistant herbs are Pinelliae Rhizoma, Paeoniae Radix alba, and Schisandrae Fructus, and envoy herb is Glycyrrhizae Radix preparata. Conclusions : In conclusion, socheongnyong-tang must differently formulate the system of chief, deputy, assistant, and envoy according to the grade of exterior wind-cold and interior water accumulation. These results suggest that socheongnyong-tang can be applied flexibly when applied in clinical practice to enhance the therapeutic effect.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.29 no.2
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• pp.35-56
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• 2018

This study examines the current state of library related data opened through public data portals, and analyzes how much data is being utilized according to the type of releasing organization, and open level. In addition, we analyzed the subject cluster of data and the centrality of data by performing PathFinder Network analysis using keywords assigned to data by dividing the releasing subject into local government and national/public institutions. Based on this, the subject area of library - related data disclosed by local governments and national/public organizations is understood. And identify the main open body that should be opened first by linking with data utilization analysis result and then suggest implications for future improvement in connection with library big data business.

• Journal of the Korean Chemical Society
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• v.29 no.2
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• pp.129-136
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• 1985

In the atomic absorption spectrometry using an air-acetylene flame, the interferences of Zr, Sn, Al, Sb, $SO_4^{2-},\;VO_3^-,\;and\;SiO_3^{2-}$, on the calcium absorption and the repression of this interference by the addition of cerium have been studied. The interference by Zr, Sn, Al, Sb, $SO_4^{2-},\;VO_3^-,\;and\;SiO_3^{2-}$ existed as the same concentration as calciurn ($3.0 {\times} 10^{-4}$M) in the sample solution are completely released by the addition of cerium twice as much as interfering cation. The interferences by the mixed interfering cations (Zr, Sn, Al and Sb) and by the mixed interfering anions ($SO_4^{2-},\;VO_3^-,\;and\;SiO_3^{2-}$) are larger than by each interfering cation and anion, and the releasing effect by cerium ($1.5 {\times} 10^{-2}$M) is effective up to some degree of the concentration of mixed interfering cations and of mixed interfering anions. The releasing effect by cerium to the mixed solution of interfering cations and anions is applicable to quite wide range of concentration.