• Title/Summary/Keyword: Relaxation Time

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Quantitative Evaluation of Liver Fibrosis on T1 Relaxometry in Comparison with Fibroscan (Fibroscan과 비교를 통한 T1 MR Relaxometry를 이용한 간섬유화의 정량적 평가)

  • Byeong Hak Sim;Suk Hee Heo;Sang Soo Shin;Seong Beom Cho;Yong Yeon Jeong
    • Journal of the Korean Society of Radiology
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    • v.81 no.2
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    • pp.365-378
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    • 2020
  • Purpose This study was performed to determine whether the T1 relaxation time of gadoxetic acid-enhanced liver MR imaging is useful for detecting and staging liver fibrosis in patients with chronic liver disease. Materials and Methods One hundred and three patients with suspected focal liver lesion underwent MR imaging and Fibroscan. Fibroscan was chosen as the reference standard for classifying liver fibrosis. T1 relaxation times were acquired before (preT1), 20 minutes after (postT1) contrast administration, and reduction rate of T1 relaxation time (rrT1) on transverse 3D VIBE (volumetric interpolated breath-hold examination) sequence using 3T MR imaging. The optimal cut-off values for the fibrosis staging were determined with ROC analysis. Results PreT1 and postT1 increased and rrT1 decreased constantly with increasing severity of liver fibrosis according to the METAVIR score (F0-F4). There were statistically significant differences between F2 and F3 in preT1 (F2, 836.0 ± 74.7 ms; F3, 888.6 ± 77.5 ms, p < 0.05) and between F3 and F4 in postT1 (F3, 309.0 ± 80.2 ms; F4, 406.6 ± 147.7 ms, p < 0.05) and rrT1 (F3, 65.4 ± 7.7%; F4, 57.3 ± 11.4%, p < 0.05). ROC analysis revealed that combination test (preT1 + postT1) was the best test for predicting liver fibrosis. Conclusion PreT1 and postT1 increased constantly with increasing severity of liver fibrosis. T1 mapping in gadoxetic acid-enhanced liver MR imaging could be a helpful complementary sequence to determine the liver fibrosis stage.

An Experimental Study on Time Dependency of Strain for Saturated Clay (포화점토(飽和粘土)의 변형(變形)에 있어서 시간의존성(時間依存性)에 관한 실험적(實驗的) 연구(研究))

  • Park, Byong Kee;Lee, Jin Soo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.4 no.3
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    • pp.43-52
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    • 1984
  • This paper is concerned with the strain characteristics of the time effect on the remoulded saturated day sampled from the downstream of the Yeongsan river, and the constitutive equation that can generally explain time-dependent behaviors of norma1ly consolidated clay. This paper examines whether or not the afore-said constitutive equation can be applied to the remoulded Mooan-clay. Throughout this study, the conclusions obtained are as follows. 1. Throughout the isotropic consolidation test for 7 days and the isotropic relaxation test, the existence of the static and dynamic yielding surfaces is confirmed respectively. 2. The characteristics of time effect of the deformation, namely, the existence of a unique stress-strain-time relation, is conformed from the experimental result on the Mooan-clay. 3. The prodictions of the stress path and the strain on the Cam-clay theory is not consistent with those observed during the experiments. 4. Constitutive equation(2-3-12) obtained by applying Cam-clay theory to Perzyna's elastic-viscoplasticity theory can explain the behavior of pore water pressure during isotropic stress relaxation, concerned with time dependency under undrained condition. The equation can also explain the results of the undrained triaxial compression test for the clay with different strain rate under the same or different consolidation history. 5. This constitutive equation has eight material parameters which can be determined from triaxial compression tests.

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Membrane-Ordering Effects of Barbiturates on Pure Phospholipid Model Membranes

  • Knag, Jung-Sook;Chung, Young-Za;Cho, Goon-Jae;Byun, Won-Tan;Yun, Il
    • Archives of Pharmacal Research
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    • v.15 no.3
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    • pp.196-203
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    • 1992
  • Intramolecular excimer formation of 1, 3-di(1-pyrenyl)propane (Py-3-Py) and fluorescence polarization of 1, 6-diphenyl-1, 3, 5-hexatriene (DPH) were used to investigate the effects of barbiturates on the fluidity of model membranes of phosphatidycholine (SPMVPC), phosphatidylserine (SPMVPS), and phosphatidylinositol (SPMVPI) fractions of synaptosomal plasma membrane vesicles (SPMV) isolated from bovine cerebral cortex. In a dose-dependent manner, barbiturates decreased the excimer to monomer fluorescence intensity ratio (I'/I) of Py-3-Py and increased the anisotropy(r), rotational relaxation time (P), limiting anisotropy $(r_infty)$, and order parameter (S) of DPH in SPMVPC, SPMVPS and SPMVPI. This indicates that barbiturates decreased both the lateral and rotational diffusion of the probes in SPMVPC, SPMVPS and SPMVPI. The relative potencies of barbiturates in ordering the membranes were in the order: pentobarbital > hexobarbital > amobarbital > phenobarbital. This order correlates well with the anesthetic potencies of barbiturates and the potencies for enhancement of $\gamma$-aminobutyric acid-stimulated chloride uptake. Thus, it is strongly suggested that a close relationship might exist between the membrane ordering effects of barbiturates and the chloride fluxes across SPMV.

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${29}^Si$ MAS NMR Study on Quantitative Analysis of the Amorphous Phase in a $Si_3N_4$ Powder

  • Fujimori, Hirotaka;Kitahara, Hiromoto;Ioku, Koji;Goto, Seishi;Nakayasu, Tetsuo;Yamada, Tetsuo
    • The Korean Journal of Ceramics
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    • v.6 no.2
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    • pp.155-158
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    • 2000
  • NMR study has been used for measuring precise quantity of the amorphous phase in the $Si_3N_4$powder. Care must be taken to allow the $^{29}$Si nuclear spin system to fully relax between pulses in order to make the signals proportional to the number of nuclei in each phase. $^{29}$Si MAS spectrum was decomposed into the three spectra of $\alpha$-, $\beta$-, and amorphous $Si_3N_4$assuming pseudo-Voigt function. Moreover, the Rietveld analysis of the powder X-ray diffraction data was performed to measure quantity of crystalline phases as $\alpha/\beta$ ratio.

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Preparation and characterization of ITO Thin Film By Various Substrate heating temperature (기판온도에 따른 ITO 박막의 제조 및 특성)

  • Kim, Sung Jin;Pak, Hunkyun
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.94.2-94.2
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    • 2010
  • Indium tin oxide (ITO) Thin films were grown on Non-alkarai glass Substrates by PVD method and Subsequently Subjected to ($100^{\circ}C-350^{\circ}C$) Thermal Annealing (TA) In Nitr Oxygen ambinent. Most of all, The effect of TA treatment on the structural properties were studied by using X-Ray diffraction and atomic force microscopy, while optical properties were studied by UV-Transmittance measurements. After TA treatment, the XRD spectra have shown an effective relaxation of the residual compressive stress, As a result, XRD peaks increase of the intensity and narrowing of full width at half-maximun (FWHM). In addtion The microstructure, The surface morphology, the optical transmittance changed and improved, and we investigated The effects of temperature, Time and atmosphere during the TA on the structural and electrical properties of the ITO/glass on TA at $300^{\circ}C$. As a results, the films are highly transparent (80%~89%) in visible region. AFM analysis shows that the films are very smooth with root mean square surface roughness 0.58nm -2.75nm thickness film. It is observed that resistivity of the films drcreases T0 $1.05{\times}10^{-4}{\Omega}cmt$ $6.06{\times}10^{-4}{\Omega}cm$, while mobility increases from $152cm^2/vs$ to $275cm^2/vs$.

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Green Generation and Investigation of Optical Properties of Amorphous BaTiO3 by Poling (폴링에 의한 비정질 BaTiO3 박막의 광학적 특성 조사 및 녹색광 발생)

  • Kim, Eung-Soo
    • The Journal of the Korea institute of electronic communication sciences
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    • v.15 no.1
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    • pp.39-44
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    • 2020
  • BaTiO3 thin films was deposited on the slide glass by RF sputter. We have investigated the optical properties of BaTiO3 film after corona poling process. The transmission characteristics was very good over 80% in visible region and second order nonlinear optical coefficient depends on the poling conditions. The nonlinear optical coefficient of poled BaTiO3 films was about 1.15pm/V. The relaxation of second order nonlinear optical was remained around 60% of the initial value for a long time. In addition we have observed the green light generation from BaTiO3 films.

Introduction to Online Based Trauma-Focused Cognitive Behavioral Therapy Education Program for Helping Sexually Abused People (성폭력피해자를 돕기 위한 온라인 기반 외상-초점 인지행동치료 교육프로그램에 대한 소개)

  • Cho, Young-Sung;Song, Jiyoun;Lee, Jun-Young
    • Anxiety and mood
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    • v.12 no.2
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    • pp.79-85
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    • 2016
  • Sexually abused victims suffer not only physical damage, but they may also experience an array of additional problems ranging from acute fear, depressed mood, anxiety, shame, or insomnia to long-term psychiatric disorders. Trauma Focused Cognitive Behavioral Therapy (TF-CBT) is known to have excellent therapeutic effects for trauma victims including victims of sexual violence. CBT treatment includes stress immunity training, relaxation training, and acceptance and commitment therapy. In foreign countries TF-CBT is carried out online in order to increase the therapeutic accessibility for the victim and improve the quality of the interview for the therapists. As a result, those victims who have difficulties in requesting external help, who live in remote areas, or who have limited time may now have access to the service and benefit from the online education programs. A website providing an online based TF-CBT program was initiated in Korea also. Through the website, victims and their guardians may obtain therapeutic information without the need for face-to-face meetings with therapists. Our goal is to create a system with this website which will provide therapeutic assistance to sexual violence victims and improve the quality of the counseling provided by the therapist.

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The Electronic and Thermoelectric Properties of Si1-xVx Alloys from First Principles

  • Ramanathan, Amall Ahmed;Khalifeh, Jamil Mahmoud
    • Applied Microscopy
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    • v.47 no.3
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    • pp.105-109
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    • 2017
  • The effect of temperature and vanadium metal concentration on the electronic and thermoelectric properties of Si in the diamond cubic structure has been investigated using a combination of density functional theory simulations and the semi classical Boltzmann's theory. The BotzTrap code within the constant relaxation time approximation has been used to obtain the Seebeck coefficient and other transport properties of interest for alloys of the structure $Si_{1-x}V_x$, where x is 0, 0.125, 0.25, 0.375, and 0.5. The thermoelectric properties have been extracted for a temperature range of 300 K to 1,000 K. The general trend with V atom substitution for Si causes the Seeback coefficient to increase and the thermal conductivity to decrease for the various alloys. The optimum values are for $Si_5V_3$ and $Si_4V_4$ alloys for charge carrier concentrations of $10^{21}cm^{-3}$ in the mid temperature range of 500~800 K. This is a very desirable effect for a promising thermoelectric and the figure of merit ZT approaches 0.2 at 600 K for the p-type $Si_5V_3$ alloy.

Influence of Endurance tests on Space Charge Distribution of 160kV HVDC XLPE Cable

  • Liu, Yun-Peng;Liu, He-Chen
    • Journal of Electrical Engineering and Technology
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    • v.12 no.1
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    • pp.302-309
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    • 2017
  • The ageing of XLPE cable insulation will lead to the accelerating accumulation of space charge, which will greatly affect the safe operation of the HVDC cable. In order to investigate the influence of different ageing modes on the space charge distribution of the HVDC cable, thermal stressed, electrical stressed and electro-thermal stressed endurance tests were carried out on the XLPE peelings. The tested XLPE peelings were obtained from 160kV HVDC cable insulation. The endurance tests were carried at thermal stress of 363K, electrical stress of 20kV/mm DC and a combination of both. The Pulsed Electro-Acoustic (PEA) method was used to measure the space charge distribution of the samples. The influences of ageing on the trap energy distribution were analyzed based on the isothermal relaxation theory and the decay characteristics of the space charge. The results showed that thermal ageing would help to improve the crystalline morphologies of the XLPE at the early stage. The total amount of space charge decreased compared to the ones before thermal ageing. The long term of electrical stress would result in the cleavage of polymer molecule chains which would intensify the accumulation of space charge and increase the density and depth of electron traps. With a combination of electrical and thermal stress, the injection and migration of space charge were more significant. Besides, the depth and density of electron traps increased rapidly with the increase of endurance time.

Mesoscale modeling of the temperature-dependent viscoelastic behavior of a Bitumen-Bound Gravels

  • Sow, Libasse;Bernard, Fabrice;Kamali-Bernard, Siham;Kebe, Cheikh Mouhamed Fadel
    • Coupled systems mechanics
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    • v.7 no.5
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    • pp.509-524
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    • 2018
  • A hierarchical multi-scale modeling strategy devoted to the study of a Bitumen-Bound Gravel (BBG) is presented in this paper. More precisely, the paper investigates the temperature-dependent linear viscoelastic of the material when submitted to low deformations levels and moderate number of cycles. In such a hierarchical approach, 3D digital Representative Elementary Volumes are built and the outcomes at a scale (here, the sub-mesoscale) are used as input data at the next higher scale (here, the mesoscale). The viscoelastic behavior of the bituminous phases at each scale is taken into account by means of a generalized Maxwell model: the bulk part of the behavior is separated from the deviatoric one and bulk and shear moduli are expanded into Prony series. Furthermore, the viscoelastic phases are considered to be thermorheologically simple: time and temperature are not independent. This behavior is reproduced by the Williams-Landel-Ferry law. By means of the FE simulations of stress relaxation tests, the parameters of the various features of this temperature-dependent viscoelastic behavior are identified.