• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.2
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• pp.457-462
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• 2004

Bambusae Caulis in Liquamen has been used as a herbal medicine for the treatment of heat, paralysis of the hands or feet, or hemiplegia. In the present study, we investigated the effect of Bambusae Caulis in Liquamen to the phenylephrine (PE) induced contraction of isolated rat aorta Contractile force was measured with force displacement transducer under 1.5 g loading tension. Contractions evoked by PE 0.1 μM were significantly increased by low dosage of Bambusae Caulis in Liquamen, decreased by high dosage of Bambusae Caulis in Liquamen. L-NNA, ODQ and propranolol significantly altered the effect of Bambusae Caulis in Liquamen, but indomethacin did not change the relaxation of Bambusae Caulis in Liquamen. These results suggest that Bambusae Caulis in Liquamen can relax EP induced contraction of isolated rat aorta and that this decreasing contraction related to sympathetics.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.5
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• pp.1299-1304
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• 2003

This study is to determine the effect of Fructus Rubi to the phenylehrine (PE) induced contraction of isolated rat aorta. Contractile force was measured with force displacement transducer under 1.5g loading tension. Contractions evoked by PE 0.1 μM and KCI 65.4 mM were decreased significantly by Fructus Rubi. L-NNA, ODQ, indomethacin and atropine significantly altered the effect of Fructus Rubi, but propranolol did not change the relaxation of Fructus Rubi. These results indicate that Fructus Rubi can relax EP and KCI induced contraction of isolated rat aorta and that this decreasing contraction related to epithelium, nitric oxide, and parasympathetics.

• Journal of Life Science
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• v.11 no.1
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• pp.62-69
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• 2001

This study was aimed to investigate the effect Chukdamtanggamibang on the vascular systems including changes in blood pressure and regional cerebral blood flow(rCBF) of male Sprague-Dawely rats, contractile force of guinea pig`s tracheal smooth muscle and abdominal aorta and femoral artery in rabbits. Blood pressure was not affected by Chukdamtanggamibang in rats. rCBF was significantly increased by Chukdamtanggamibang in a dose-dependent manner. Contractile force of isolated guinea pig`s tracheal smooth muscle evoked by His ({TEX}$ED_{50}${/TEX}) were inhibited significantly by Chukdamtanggamibang. Propranolol, indomethacin and methylene blue did not significantly alter the inhibitory effect of Chukdamtanggamibang. Contractile force of isolated rabbit`s abdominal aorta and femoral artery evoked by NE ({TEX}$ED_{50}${/TEX}) were inhibited significantly by Chukdamtanggamibang. ODQ and L-NNA significantly attenuated the inhibitory effects of Chukdamtanggamibang in abdominal aorta, whereas propranolol did not significantly alter the inhibitory effect of Chukdamtanggamibang. These results indicate that Chukdamtanggamibang can relax hitamine-induced contraction of guinea pig`s tracheal smooth muscle and that this inhibition involves, in part, the relation to the soluble guanylyl cyclase synthesis and nitric oxide (NO) synthesis.

• Korean Journal of Bronchoesophagology
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• v.4 no.1
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• pp.64-72
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• 1998

This study aimed at observing the effect of diazepam on the contractility of trachealis muscle isolated from canine trachea, possible involvement of central or peripheral type benzodiazepine receptor, and the calcium related mechanism of action of diazepam. Trachealis muscle strips of 15 mm long were suspended in an isolated organ bath containing 1 ml of physiologic salt solution maintained at $37^{\circ}C$, and aerated with 95% $O_2$ /5% $CO_2$. Isometric myography was performed. Diazepam reduced the basal tone concentration dependently, and this inhibitory action was not affected by neither flumazenil, a central benzodiazepine receptor antagonist, nor PK11195, a peripheral benzodiazepine receptor antagonist. Pretreatment with diazepam showed the inhibitory effect on the concentration-response curves to agonists such as bethanechol, 5-hydroxytryptamine and histamine. Diazepam also caused concentration-related inhibition of contraction with potassium chloride 30 mM. The effect of diazepam on the basal tone and potassium chloride-induced contraction with calcium channel blockers were compared. Similar results were obtained in canine trachealis with verapamil, nifedipine and diltiazem. These results suggest that diazepam relax an airway muscle not via specific receptors but by a similar action as calcium channel blockers in canine trachealis muscle.

• Proceedings of the Polymer Society of Korea Conference
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• 2006.10a
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• pp.338-338
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• 2006

Equilibrium behavior of ABA triblock copolymer with different lengths of endblock A chains was examined using self-consistent field theory by Matsenl. It was found that at small asymmetries, the A block bidispersity reduces the stretching energy of the A domains. This effect causes a slight increase in the domain spacing and shifts the order-order transitions toward higher A volume fractions. At large asymmetries, the short A blocks pull free of their domains allowing their B blocks to relax. A feature of microphase-separated structure of asymmetric poly(methyl acyrylate) (PMA)-b-polystyrene-b-PMA using SAXS, DSC and ESR was experimentally examined. These measurements gave an evidence of the solubilization of short A chains to the B domains.

• KIEAE Journal
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• v.1 no.1
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• pp.27-33
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• 2001

There are many research Papers and experiments indicating that the geomagnetic field affects the people and living organism. People grow up and build up most of their character through living in dwelling space and have relax and refresh at home. Creating healthy dwelling space is being considered very important in architectural planning and design for providing comfortable living environment and improving quality of life. Therefore. it is necessary to investigate the geomagnetic field and people's response in living space. In this study the vertical component(Z value) of geomagnetic field in detached houses was measured, evaluated by related evaluation criteria, compared with interview survey.

• Proceedings of the KSPS conference
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• 2000.07a
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• pp.96-104
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• 2000

The Bodysonic system was invented on the basis of 'Bone Conduction Theory,' which states that people feel sounds with their whole body. The Bodysonic system is used for L2 (English) learning at Aichi Women's Junior College. In recent years we have developed some unique methodology related to use of the Bodysonic system. In Japan it is difficult for adult L2 learners to acquire the prosody of a foreign language. A language laboratory using the Bodysonic system has been suggested as one way to eradicate such adult L2 problems. The Bodysonic system changes sounds into vibrations. It makes it easy for learners to acquire the prosody of a foreign language because humans can convey information, through their tactile organs. In addition, this system was originally designed to make people relax, so it can also help minimize learner anxiety. The effect of Bodysonic vibrations on language learning has already been proven by some experiments. The Bodysonic system appears to be an ideal teaching method for adult to learn a foreign language.

• Journal of Korean Society for Quality Management
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• v.20 no.2
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• pp.55-66
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• 1992

The sampling plan CSP-1 for continuous production was first proposed by Dodge in 1943. Continuous production refers to products which are flowing past the inspection station such as products moving on a conveyor belt. One important measure of the effectiveness of a CSP is the average outgoing quality(AOQ). A concept for a short run of production length time, denoted by AOQ(t), is provided. The assumption of a s-independence in CSP-1 is unrealistic. It is possible to relax the assumption of a s-independence. The need for Markov model in a continuous production process can be discussed in this paper. The Markov and renewal theory are used to describe the property of AOQ in CSP-1.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.180.1-180.1
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• 2003

Eukaryotic DNA topoisomerase I (top I) is an essential enzyme that act to relax supercoiled DNA during the transcription, replication and mitosis. Intracellular levels of top I are elevated in a number of human solid tumors, relative to the respective normal tissues, suggesting that controlling the topI level is important to treat cancer. Top I poisons show their antitumor activities by stabilizing the cleavable ternary complex consisting of top I enzyme, DNA, and drug. Thus, top I is a promising target for the development of new cancer chemotherapeutics against a number of solid tumors. (omitted)

• International journal of advanced smart convergence
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• v.9 no.4
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• pp.203-208
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• 2020

In this paper, we propose the design and implementation of a desktop LED stand and smart app that automatically adjusts color temperature and illuminance for optimal brightness and eye health by improving the structural problem of the LED stand. It is a tabletop LED stand that supports optimal brightness through color temperature control and heat transfer through infrared LED to relieve eye strain through blood circulation and muscle movement. The LED stand works with the smartphone to automatically adjust the optimal brightness and color temperature for the user's environment. In addition, the brightness of the infrared LED is adjusted to a living frequency of 4Hz to relax the eye muscles and reduce eye strain. This study implemented an effective measured data-based system of previous studies through the color temperature and illumination of LED lighting, and near-infrared rays, and presented meaningful results by conducting an experiment to prove the effect through subjects.