• Title/Summary/Keyword: Relative stability

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The Effects of Pseudopolymorphism on the Relative Bioavailability of Amoxicillin (결정다형이 아목시실린의 상대적 생체이용률에 미치는 영향)

  • 손영택
    • YAKHAK HOEJI
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    • v.39 no.4
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    • pp.438-443
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    • 1995
  • Four different pseudopolymorphs of amoxicillin-trihydrate, dehydrate, monohydrate and anhydratewere prepared and characterized by UV spectrophotometry, DSC, and TGA. In vitro dissolution studies of four pseudopolymorphs were carried out in pH 6.8 phosphate buffer at $37^{\circ}C$ by means of a rotating disk method. The effect of four pseudopolymorphs on bioavauability of amoxicillin was studied in healthy 6 subjects using urinary excretion method. The dissolution result was shown in the sequence, trihydrate(95.5%)>monohydrate(83.5%)>anhydrate(67.6%)>dihydrate(15.8%). The urinary excretion rate of anhydrate could not be detected and the dissolution results agreed well with in vivo phannacoldnetic study results. The effects of storage conditions, milling and compression on the pseudopolymorpnc transformation were investigated by thermal methods. The results showed that four pseudopolymorphs were not transformed and they were very stable.

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Transient Characteristics of Separately Excited d-c Motor Driven by Thyristor d-c Chopper (Thyristor 직류 Chopper방식으로 구동되는 직류타여자식 전동기의 과도특성해석법)

  • Hee Young Chun
    • 전기의세계
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    • v.21 no.2
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    • pp.9-19
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    • 1972
  • The transient characteristics of separately excited d-c motor driven by thyristor d-c chopper is studied in this paper. The armature controlled system is applied. As a result of theoretrical analysis the following conculsions were drawn: (1) For the transient analysis, it is recognized that the state transition analysis is a more general method and powerful tool than the state equation method or signal flow graph method, although it includes iterative matrix calculations. And the system is dealt with a finite width sampled-data system in the state transition analysis. (2) The transient characteristics of the motor angular velocity and its torque to the sampling duration variation are compared with those due to the amplitude variation of d-c chopper voltage as follows. The attenuation rate of the transient characteristics is equal in both cases, but the initial value of the transient characteristics in former case is greater than in latter case. (3) The roots of characteristics equation of the system lie inside the unit circle of the Z-plane. Therefor the system is stable. Further it is found that as the sampling duration is decreased the relative stability is lessened.

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Understanding of dynamic system properties in the frequency domain using bond graphs (본드선도를 이용한 동적시스템의 주파수역 특성이해)

  • Park, Jeon-Soo;Kim, Jong-Shik
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.22 no.4
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    • pp.801-810
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    • 1998
  • Modeling and analysis of dynamic systems generally demand their resutls to be interpreted each other with a physical sense. It sometimes requires that there should exist a unified tool in the treatment of dynamic systems which can be applied to both their modeling and analysis equally. This paper shows how models just after the progress of modeling via bond graph standards are converted to ones which are appropriate for analyzing a dynamic system in the frequency domain. Four bond graph prototypes are introduced to obtain frequency properties of dynamic systems such as zero stability, relative order, zero and pole dynamics, etc. directly from bond graphs, and the method are proposed which reduces nearly all models of bond graph standards to one of the prototypes without any change of physical similarity. This procedure as a tool for the structural reduction of bond graphs and finding frequency properties of a dynamic system is further investigated to survey its effectiveness through an example.

Analysis of the Foam Generated Using Surfactant Sodium Lauryl Sulfate

  • Ranjani, G. Indu Siva;Ramamurthy, K.
    • International Journal of Concrete Structures and Materials
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    • v.4 no.1
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    • pp.55-62
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    • 2010
  • The performance evaluation of a sodium lauryl sulfate to qualify as a foaming agent is presented in this paper. When new surfactants are used a systematic study of production parameters on the foam characteristics needs to be undertaken unlike proprietary foaming agents and foam generator for which manufacturer has predefined the parameters. The relative influence of the foam parameters and optimization of factors were carried out through a systematic experiment design. The foam production parameters namely foam generation pressure and dilution ratio of foaming agents are observed to have significant effect on all foam characteristics with the exception of foam output rate on which only foam generation pressure has influence. The foam with good initial foam density need not necessarily be stable foam. The optimum levels of foam production parameters are determined for the surfactant Sodium lauryl sulfate which can be used to produce stable foam for foam concrete production.

The Seek Control Design with Gain-Scheduling in Hard Disk Drives

  • Hwang, Eun-Ju;Hyun, Chang-Ho;Park, Mig-Non
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.11 no.1
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    • pp.65-70
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    • 2011
  • The increased disk rotational velocity to improve the data transfer rate has raised up many serious problems in its servo control system which should control the position and velocity of a spot relative to a rotating disk. This paper proposes gain-scheduling-based track-seek control for single stage actuator of hard disk drives. Gain scheduling is a technique that can extend the validity of the linearization approach to a range of operating points and one of the most popular approaches to nonlinear control design. The proposed method schedules controller gains to improve the transient response and minimize overshoot during the functions of the read/write head positioning servomechanism for the seek control. The validity of the proposed method is demonstrated through stability analysis and simulation results.

Prediction and Measurement of Cutting Force in Side-Milling (사이드 밀링 가공의 절삭력 측정 및 예측)

  • Lee, Chang-Ho;Yang, Min-Yang
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.22 no.3
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    • pp.437-446
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    • 2013
  • There have been numerous studies on end milling processes. However, these have been restricted to the application of tools for special cutting purposes. A side milling cutter can handle long, deep, and open slots in a more efficient manner, and it provides the best stability and productivity for this type of milling. In this paper, a method to predict the cutting forces in side milling is described, and simulated cutting forces are compared with those obtained by cutting experiments. In particular, the side milling process easily generates relative motion between the tools and the workpiece because it produces intermittent cutting forces that cause vibrations over a wide frequency range. Therefore, the application of a dynamic cutting model instead of a static cutting model is appropriate to forecast the cutting forces more accurately.

Dynamic Stability of Cutting System in Lathe Turning (선삭에서 절삭계의 동적안정성 향상에 관한 연구)

  • Chung, Joon-Ki;Lee, Hyung-Sik
    • Journal of the Korean Society for Precision Engineering
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    • v.1 no.2
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    • pp.33-40
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    • 1984
  • Chatter is a relative vibration between workpiece and tool in machining of metals, and is an important limiting factor of production rate and surface quality, and also reduces the life of machine-tool itself and its tool. In this study, in order to suppress the machining chatter, the spring and the rubber damper are adopted to the tool post of a lathe. The results obtained in this experimental study are summarized as follows. 1. The spring and the damper employed in the tool post for the suppression of chatter increase the maximum chatter-free depth of cut and optimum values found for spring constant and compressive strain are 95kg/mm, 0.1954 respectively. 2. On the optimum condition resulting in this experimental study, the modified tool post increased 6 times in the maximum chatter-free depth of cut as compared with the conventional tool post.

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ADAPTIVE BACKSTEPPING CONTROL FOR SATELLITE FORMATION FLYING WITH MASS UNCERTAINTY

  • Lim, Hyung-Chul;Bang, Hyo-Choong;Lee, Sang-Jong
    • Journal of Astronomy and Space Sciences
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    • v.23 no.4
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    • pp.405-414
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    • 2006
  • Satellite formation flying has become a critical issue in the aerospace engineering because it is considered as an enabling technology for many space missions. Thus, many nonlinear control theories have been developed for the tracking problem of satellite formation flying, which include full-nonlinear dynamics, external disturbances and parameter uncertainty. In this study, nonlinear adaptive control law is developed using an adaptive backstepping technique to solve the relative position tracking problem of the satellite formation flying in the presence of mass uncertainty and the bounded external disturbance. Simulation studies are included to demonstrate the proposed controller performance. The proposed controller is shown to guarantee the system stability against the external bounded disturbances in the presence of mass uncertainty.

A study on hydrodynamic characteristics of artificial upwelling structures (인공용승구조물의 수리학적 기능성에 관한 연구)

  • Kim, Hong-Jin;Jeon, Yong-Ho;Ryu, Cheong-Ro
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2002.05a
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    • pp.62-67
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    • 2002
  • While upwelling regions account for only 0.1% of the ocean surface, they yield over 40% of world's fish catch. Thus it is vary important making upwelling region by various methods. This study was performed to find out basic hydrodynamic characteristics (function, stability..,) of artificial upwelling structures. The hydrodynamic characteristics of artificial upwelling structures can be summarized as follows: 1) The falling velocity of blocks was effected size($l_B$) of blocks than incident current velocity( $V_0$). 2) The falling horizontal distance was reduced as induce of stratification parameters and block' size. 3) Generation of artificial upwelling current was effected by size of structures and incident current. When stratification parameters was about 3.0 and relative height(hs/h) of structures was about $0.125{\sim}0.15$, stable artificial upwelling current was generated in the back-side of structures.

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On the Development of the Statistical $SO_2$ Forecasting Technique by the Multiple Regression Analysis in Wonju City (중회귀식을 이용한 원주시 $SO_2$ 오염도 예보기법 개발에 관한 연구)

  • 송동웅
    • Journal of Environmental Science International
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    • v.7 no.6
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    • pp.827-831
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    • 1998
  • Statistical $SO_2$ forecasting technique by multiple regression analysis was designed and developed to predict $SO_2$ concentration in Wonju City. $SO_2$ concentration data measured from air pollution monitoring system and meteorological factors data such as : wind speed, atmospheric stability, surface temperature, relative humidity and precipitation were used in Wonju City during the 1996~1997. As the results, correlation model for forecasting was well fitted with some parameters including minimum temperature, wind speed and the $SO_2$ concentration of the previous day.

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