• 제목/요약/키워드: Relative sensitivity

검색결과 663건 처리시간 0.027초

SLURP 모형을 이용한 유출수문분석 - 소양강댐 유역을 대상으로 - (Hydrological Analysis in Soyanggang-dam Watershed Using SLURP Model)

  • 임혁진;권형중;장철희;김성준
    • 한국수자원학회논문집
    • /
    • 제37권8호
    • /
    • pp.631-641
    • /
    • 2004
  • 본 연구는 개념적 준분포형 모형인 SLURP 모형의 소양강댐유역의 적용가능성에 대해 다루었다. SLURP모형은 강우의 시공간적 변화를 반영하여 강우-유출을 해석하여 관개계획 및 수자원 관리 효과를 판단할 수 있는 준분포형 모형이다. DEM으로부터 지형분석프로그램인 TOPAZ/SLURPAZ와 연계하여 빠르고 쉽게 지형매개변수와 지형자료를 획득할 수 있다. NOAA/AVHRR 위성영상을 이용하여 월별 NDVI를 산출하였으며, 대상유역 주변의 5개의 기상 관측소를 통해 일별 수문기상자료(이슬점, 일사량, 최대ㆍ최소 대기 기온, 상대습도 등)을 얻었다. DEM NDVI, 수문기상자료를 이용하여 1998년부터 2001년까지 4 개년도의 일별유출량을 모의하였다. 매개변수 최적화를 위하여 민감도 분석 및 SCE-UA 방법을 사용하였으며 대상기간의 Nash-Sutcliffe의 모형효율과 WMO 통계량을 통해 소양강댐 유역의 SLURP모형의 적용성을 검증하였다.

Spectrofluorimetric Determination of Sparfloxacin Using Europium(III) as a Fluorescence Probe in Micellar Medium

  • Kamruzzaman, Mohammad;Alam, Al-Mahmnur;Lee, Sang-Hak;Kim, Young-Ho;Kim, Sung-Hong;Kim, Gyu-Man
    • Bulletin of the Korean Chemical Society
    • /
    • 제33권1호
    • /
    • pp.105-110
    • /
    • 2012
  • A europium (III)-sensitized, spectrofluorimetric (FL) method is presented for the determination of sparfloxacin (SPAR) using an anionic surfactant, sodium dodecyl benzene sulphonate (SDBS). The method is based on the strong fluorescence (FL) enhancement of SPAR after the addition of $Eu^{3+}$ ions as fluorescence probes. The experimental results indicated that the FL intensity of the SPAR-$Eu^{3+}$ system was enhanced markedly by SDBS. The maximum FL emission signal was obtained at about 615 nm when excited at 372 nm. The experimental conditions that affected the FL intensity of the SPAR-$Eu^{3+}$-SDBS system were optimized systematically. The enhanced FL intensity of the system exhibited a good linear relationship with the SPAR concentration over the range of $1.5{\times}10^{-9}-1.2{\times}10^{-7}mol\;L^{-1}$ with a correlation coefficient (r) of 0.9987. The limit of detection ($3{\delta}$) was $4.15{\times}10^{-10}mol\;L^{-1}$ with a relative standard deviation (RSD) of 1.65%. This method was successfully applied for the determination of SPAR in pharmaceuticals, and human serum and urine samples with higher sensitivity, wide dynamic range and better stability. The possible interaction mechanism of the system is also discussed in detail by ultraviolet absorption spectra and FL spectra.

한국 장년 성인의 과체중 예방을 위한 식생활 간이평가표 개발 (The Development of a Simple Evaluation Questionnaire for Screening the Overweight-type Dietary Pattern in 30 to 49 Year Old Adults)

  • 박영숙;한재라;이정원;조한석;구재옥;김정희;윤진숙
    • 대한지역사회영양학회지
    • /
    • 제7권4호
    • /
    • pp.495-505
    • /
    • 2002
  • A study was performed to develop as a screening tool the Simple Evaluation Questionnaire for Screening the Over-weight-type Dietary Pattern in 30 to 49 Year Old Adults. We used the data from the 30 to 49 year old subjects who participated in the three surveys - the health behavior survey, the dietary habit survey and the food intake survey - as the National Health and Nutrition Survey 1998. The 3,598 adults were classified into to two body fatness groups of normal (including underweight) and overweight (including obese) on the basis of their relative body weight (RBW) When comparing variables between the two groups, significant differences were found in gender, education, job, employment status, perceived health status, sadness / depression state, stress level, age, number of diseases, age when overweightedness started, maximum body weight, sleep length, drinking pattern (yes/no) , amount of alcoholic drinks, frequency of intoxication or drunkeness, amount of alcoholic drinks when drunk, intensity of exercise, frequency of exercise, exercise duration, skipped meals, small meals and drug supplements. In terms of food intake, there were significant differences in the daily food intake in terms of breakfast, dinner, daily kimchi and dairy products. In terms of mealtimes, we found differences in the amount of cooked rice at breakfast, kimchi at lunch, soup / kuk at dinner, fresh vegetables for snacks, fried foods for snacks between breakfast and lunch, and fruits /juices for snacks between lunch and dinner. After developing questions with indicators and analyzing the indicators by logistic regression analysis three times, we chose 10 questions for a simple evaluation of dietary patterns for the overweight-type category in order to give one point each. Among them we selected two questions to add one additional point and one question to add two additional points. The average scores of the overweight and normal groups, as shown by the developed questionnaire, were $5.97 \pm 2.36 \pm 7.36 \pm 2.21$, respectively. A score of seven points was selected as the cut-off point. We examined the sensitivity, specificity and positive predictive value of the questionnaire to the results of 67%, 59% and 62%, respectively.

단순 디지털 촬영과 저선량 CT의 폐기종 소견으로부터 폐쇄성 폐기능 장애 위험 비교 (Evaluation of Obstructive Pulmonary Function Impairment Risks in Pulmonary Emphysema Detected by Low-Dose CT: Compared with Simple Digital Radiography)

  • 이원정;이정오;최병순
    • Tuberculosis and Respiratory Diseases
    • /
    • 제71권1호
    • /
    • pp.37-45
    • /
    • 2011
  • Background: Pulmonary emphysema (PE) is major cause of obstructive pulmonary function impairment (OPFI), which is diagnosed by spirometry. PE by high resolution CT is known to be correlated with OPFI. Recently, low dose CT (LDCT) has been increasingly used for screening interstitial lung diseases including PE. The aim of this study was to evaluate OPFI risks of subjects with PE detected by LDCT compared with those detected by simple digital radiography (SDR). Methods: LDCT and spirometry were administered to 266 inorganic dust exposed retired workers, from May 30, 2007 to August 31, 2008. This study was approved by our institutional review board and informed consent was obtained. OPFI risk was defined as less than 0.7 of forced expiratory volume in one second (FEV1)/forced vital capacity (FVC), and relative risk (RR) of OPFI of PE was calculated by multiple logistic regression analysis. Results: Of the 266 subjects, PE was found in 28 subjects (10.5%) by LDCT and in 11 subjects (4.1%) by SDR; agreement was relatively low (kappa value=0.32, p<0.001). FEV1 and FEV1/FVC were significantly different between PE and no PE groups determined by either SDR or LDCT. The differences between groups were larger when the groups were divided by the findings of SDR. When PE was present in either LDCT or SDR assays, the RRs of OPFI were 2.34 and 8.65, respectively. Conclusion: LDCT showed significantly higher sensitivity than SDR for detecting PE, especially low grade PE, in which pulmonary function is not affected. As a result, the OPFI risks in the PE group by LDCT was lower than that in the PE group by SDR.

MFAC를 사용한 근접관계의 분류 (Classification of Proximity Relational Using Multiple Fuzzy Alpha Cut(MFAC))

  • 류경현;정환묵
    • 한국지능시스템학회논문지
    • /
    • 제18권1호
    • /
    • pp.139-144
    • /
    • 2008
  • 일반적으로 의사결정의 대상이 되는 현실 시스템은 매우 가변적(variable)이며 때로는 많은 불확실성(uncertainty)이 포함된 상황에 놓일 수 있다. 이러한 문제를 해결하기 위해서, 통계적 방법으로 유의수준이나 확신도, 민감도 분석 등이 사용된다. 본 논문에서는 유사성 평가를 가진 분류 결과의 명확성을 개선하기 위해 MFAC(Multiple Fuzzy Alpha Cut)을 기반으로한 퍼지 의사결정에 대한 방법을 제안한다. 제안된 방법에서 MFAC는 상대적 해밍거리와 max-min 방법 사이의 근접관계에서 근접도를 가지고 다수의 ${\alpha}$-level를 추출하기 위해 그리고 MFAC에 의해 추출된 데이터사이의 분할 구간과 연관된 데이터의 개수를 줄이기 위해 사용된다. 의사결정의 최종 대안을 선택하기 위해서 가중치를 계산한다. 실험결과로부터 제안된 방법은 기존 방법의 분류 성능보다 더 간단하고 명백하며 통계적 방법을 통해 표본 데이터의 유의성을 검정함으로써 의사결정자를 위해 효율적으로 대안을 결정한다는 사실을 알 수 있다.

A qualitative evaluation method for engine and its operating-envelope using GSP (Gas turbine Simulation Program)

  • Kyung, Kyu-Hyung;Jun, Yong-Min;Yang, Soo-Seok;Choi, Dong-Whan
    • 한국추진공학회:학술대회논문집
    • /
    • 한국추진공학회 2004년도 제22회 춘계학술대회논문집
    • /
    • pp.848-853
    • /
    • 2004
  • Regarding to the project SUAV (Smart Unmanned Aerial Vehicle) in KARI (Korea Aerospace Research Institute), several engine configurations has been evaluated. However it's not an easy task to collect all the necessary data of each engine for the analysis. Usually, some kind of modeling technique is required in order to determine the unknown data. In the present paper a qualitative method for reverse engineering is proposed, in order to identify some design patterns and relationships between parameters. The method can be used to estimate several parameters that usually are not provided by the manufacturer. The method consists of modeling an existing engine and through a simulation, compare its transient behavior with its operating envelope. In the simulation several parameters such as thermodynamics, performance, safety and mechanics concerning to the definition of operation-envelope, have been discussed qualitatively. With the model, all engine parameters can be estimated with acceptable accuracy, making possible the study of dependencies among different parameters such as power-turbine total inertia, TIT, take-off time and part load, in order to check if the engine transient performance is within the design criteria. For more realistic approach and more detailed design requirements, it will be necessary to enhance the compressor map first, and more realistic estimated values must be taken into account for intake-loss, bleed-air and auxiliary power extraction. The relative importance of these “unknown” parameters must be evaluated using sensitivity analysis in the future evaluation. Moreover, fluid dynamics, thermal analysis and stress analysis necessary for the resulting life assessment of en engine, will not be addressed here but in a future paper. With the methodology presented in the paper was possible to infer the relationships between operation-envelope and engine parameters.

  • PDF

LC-MS Determination and Bioavailability Study of Imidapril Hydrochloride after the Oral Administration of Imidapril Tablets in Human Volunteers

  • Yun Ji Hye;Myung Ja Hye;Kim Hye Jin;Lee Sibeum;Park Jong-Sei;Kim Won;Lee Eun-Hee;Moon Cheol Jin;Hwang Sung-Joo
    • Archives of Pharmacal Research
    • /
    • 제28권4호
    • /
    • pp.463-468
    • /
    • 2005
  • The purpose of the present study was to develop a standard protocol for imidapril hydrochloride bioequivalence testing. For this reason, a specific LC-MS method was developed and validated for the determination of imidapril in human plasma. A solid-phase extraction cartridge, $Sep-pak^{R}$ C18, was used to extract imidapril and ramipril (an internal standard) from deproteinized plasma. The compounds were separated using a XTerra $MS^{R}$?C18 column ($3.5 {\mu}m, 2.1\times150 mm$) and $acetonitrile-0.1\%$ formic acid (67:33, v/v) adjusted to pH 2.4 by 2 mmol/L ammonium formic acid, as mobile phase at 0.3 mL/min. Imidapril was detected as m/z 406 at a retention time of ca. 2.3 min, and ramipril as m/z 417 at ca. 3.6 min. The described method showed acceptable specificity, linearity from 0.5 to 100 ng/mL, precision (expressed as a relative standard deviation of less than $15\%$), accuracy, and stability. The plasma concentration-versus-time curves of eight healthy male volunteers administered a single dose of imidapril (10 mg), gave an $AUC_{12hr}$ of imidapril of $121.48\pm35.81 ng mL^{-1} h$, and $C_{max} and T_{max}$ values of $32.59\pm9.76 ng/mL and 1.75\pm0.27 h$. The developed method should be useful for the determination of imidapril in plasma with sufficient sensitivity and specificity in bioequivalence study.

레이다 신호의 클래스 분리도 측정을 위한 연구 (Study on Class Separability Measure for Radar Signals)

  • 정성재;이승재;김경태
    • 한국전자파학회논문지
    • /
    • 제29권2호
    • /
    • pp.128-137
    • /
    • 2018
  • 본 논문에서는 레이다 신호를 위한 새로운 클래스간 분리도 측정 방법을 제시한다. 제안된 방법에서는 표적과 레이다 간의 상대적 각도 차이의 따른 레이다 신호의 민감도를 감소시키기 위해 RCS(radar cross section)의 경우 두 신호의 상관계수(correlation coefficient)를 구하고, 1차원 신호의 경우(i.e., high resolution range profile(HRRP)) 선형이동을 하며 상관계수를 구한다. 2차원 레이다 신호(i.e., inverse synthetic aperture radar(ISAR))의 경우 두 레이다 신호를 회전하면서 상관계수를 계산한다. 그런 다음, 두 레이다 신호가 가장 잘 배열되었을 경우의 최대 상관계수를 구하고, 이를 이용해 새로운 형태의 상관 기반 분리 행렬을 구성한다. 상관 기반 분리 행렬의 누적분포함수를 구하여 상위 확률에 응답하는 값을 구하였고, 그 값은 레이다 신호의 분리 능력을 정확하게 나타낸다. 제안한 방법을 이용한 실험 결과, 표적 분리 능력을 정확하게 추정할 수 있었다.

마이크로 프로세서 기반 Lock-In-Amp를 이용한 텍스타일 직물전극의 체온 측정에 관한 연구 (A Study on Body Temperature Measurement of Woven Textile Electrode Using Lock-In-Amp based on Microprocessor)

  • 이강휘;이성수;이정환;송하영
    • 전기학회논문지
    • /
    • 제66권7호
    • /
    • pp.1141-1148
    • /
    • 2017
  • Generally, a thermistor made by sintering a metal oxide is widely used to measure the ambient temperature. This thermistor is widely used not only for industrial use but also for medical use because of its excellent sensitivity, durability, temperature change characteristics and low cost. In particular, the normal body temperature is 36.9 degrees relative to the armpit temperature, and it is most closely related to the circulating blood flow. Previous studies have shown that body temperature changes during biomechanical changes and body temperature changes by anomalous signs or illnesses. Therefore, in this study, we propose a Lock-In-Amp design to detect minute temperature changes of clothing and thermistor wired by a preacher as a method to regularly measure body temperature in daily life. Especially, it is designed to measure the minute resistance change of the thermistor according to body temperature change even in a low-cost microprocessor environment by using a micro-processor-based Lock-In-Amp, and a jacquard and the thermistor is arranged so as to be close to the side, so that the reference body temperature can be easily measured. The temperature was measured and stored in real time using short-range wireless communication for non - restraint temperature monitoring. A baby vest was made to verify its performance through temperature experiments for infants. The measurement of infant body temperature through the existing skin sensor or thermometer has limitations in monitoring infant body temperature for a long time without restriction. However, it can be overcome by using the embroidery fabric based micro temperature monitoring wireless monitoring device proposed in this study.

Management of Aesthetic intentions in Urban Design -Artworks in Urban Public Space-

  • Takeda, Naoki;Yagi, Kentaro
    • Journal of the Korean Institute of Landscape Architecture International Edition
    • /
    • 제1호
    • /
    • pp.167-175
    • /
    • 2001
  • After World War II, Japan experienced a great political and social shift, which brought a concern of emerging public landscape in urban development. This paper analyses the management of the aesthetic intentions in urban design effort. We reviewed the development of various public installation of artworks concerning urban landscape aesthetics through its administrative process in chronological order. The monuments during the first decade marked a shift in emphasis from the militarism of the pre-war and wartime period to one of peace. However, some of the monuments and sculptures are not immune to controversy. This became an issue that could no be ignored by public officials whose responsibility was to place the sculptures while maintaining sensitivity to public opinion. As public administrators began to consider the possibility that sculptures may contribute to improving public amenities, the contextual concepts were basically ignored. Some of the programs in 1970s began to show more respect to the context, while other programs in this period expressed more interest in educational aspects of sculptures in the public spaces. Urban development projects also seek to introduce artworks integrated to their urban design concepts in 1990s. Generally, the administrators responsible for these programs were rarely trained in any relative field study other than public administration. Installing sculptures tended to be considered as part of public works projects on the level of urban planning and construction. The general public is basically removed from participating in the critical decisions that actually impact their lives in relation to the artworks. In conclusion, public art in japan has unique social and historic background both in its advantages and disadvantages. Issues pertaining to art in public spaces have evolved over the decades as the term "sculpture pollution" began to appear by the mid 1990s. most of the problems originated in either the lack of monumentality, contextual consideration, quality, or public participation. From another point of view, these programs played great roll in the development of modern Japanese sculpture and patronizing process, and the creation of new urban landscape with aesthetic value. In this sense, they must be considered as successful and noteworthy examples of cultural administration and urban design policy.

  • PDF