• YAKHAK HOEJI
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• v.13 no.4
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• pp.111-120
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• 1969

The determination of $\alpha$-pyrrolidone in ginseng extract by gas liquid chromatography (GLC) was established. $\alpha$-Pyrrolidone in extract was tentatively identified by comparison of the relative retention time of sample peak with those of reference compound and coinjection noted peak enhancement. The .alpha.-pyrrolidone peak elimination was demonstrated by formation of oxime when treated with excess of NH$_{2}$OH ${\cdot}$ HCl and NaOH, allowed to stand at room temperature for 5 minute. The elimination was also observed when samples were treated by the same procedure. The above method was proved to be useful for the determination of $\alpha$-pyrrolidone in ginseng extract and in ginseng extract mixed with 51 plant extracts.

• Journal of the Korean Geosynthetics Society
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• v.12 no.4
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• pp.87-98
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• 2013

This study was performed a series of the isotropic compression-expansion tests and the drained triaxial tests with various the relative densities 40%, 60%, 80% and 95% for bottom ash. Using the tests results the characteristic of the parameters of Lade's single hardening constitutive model were investigated. The soil parameters Kur and n representing elastic behavior are not much affected by the change of the relative density. The other parameters such as failure criterion(m, ${\eta}_1$), hardening function(c, p) and plastic potential(${\psi}_2$, ${\mu}$) are in a positive linear relationship with the relative density. Since the soil parameters h and ${\alpha}$ representing yield function do not change much to the change of relative density and also closely related to failure criterion, they can be replaced by failure criterion ${\eta}_1$. We also observed that predicted values from the Lade's single hardening constitutive model were well consistent with the observed data.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.1C
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• pp.11-17
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• 2011

This study was performed a series of the isotropic compression-expansion tests and the drained triaxial tests with various the relative densities 25%, 50%, 80% and 100% for Baekma river sand. Using the tests results the characteristic of the parameters of Lade's single hardening constitutive model were investigated. The soil parameters Kur and n representing elastic behavior are not much affected by the change of the relative density. The other parameters such as failure criterion (m, ${\eta}_1$), hardening function (C, p) and plastic potential (${\Psi}_2$, ${\mu}$) are in a positive linear relationship with the relative density. Since the soil parameters h and $\alpha$ representing yield function do not change much to the change of relative density and also closely related to failure criterion, they can be replaced by failure criterion ${\eta}_1$. We also observed that predicted values from the Lade's single hardening constitutive model were well consistent with the observed data.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.3
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• pp.171-180
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• 2019

Purpose : The purpose of this study was to investigate the difference in motor cortical excitability during mental practice and action observation in subjects with forward head posture. Methods : This study was performed in two groups, a forward head posture group (n=17) and a normal posture group (n=17). Electroencephalography (EEG) was conducted to investigate cerebral cortex activity, and six electrodes were attached to Fp1, Fp2, C1, C2, C3, and C4 to measure the relative alpha power, relative beta power, relative gamma power, and mu rhythms. The subjects were requested to perform the four different conditions, which were eye opening, eye closing, mental practice, and action observation for 300 seconds. Results : The results showed that the relative alpha waves showed a significant difference between the normal and forward head posture groups in the C1, C2, C3, and C4 regions with the eyes open (p<.05). The relative beta waves also showed a significant difference between the two groups in the Fp1 and Fp2 regions during action observation (p<.05). The relative gamma waves were significantly different between the normal and forward head posture groups in the Fp1 and Fp2 regions during action observation (p<.05) in C1, C2, and C3 with eyes closed (p<.05) and in C1, C2, C3, and C4 with eyes open (p<.05). Conclusion : The results of this study showed that EEG change in the forward head posture group was different from that in the normal control group in action observation rather than in mental practice. Therefore, we are expected to provide a neurophysiological basis for applying action observation to motor skill learning during exercise for correcting forward head posture.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2161-2166
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• 2015

Estrogen receptors (ERs) are steroid receptors located in the cytoplasm and on the nuclear membrane. The sequence similarities of human $ER{\alpha}$, mouse $ER{\alpha}$, rat $ER{\alpha}$, dog $ER{\alpha}$, and cat $ER{\alpha}$ are above 90%, but structures of $ER{\alpha}$ may different among species. Estrogen can be agonist and antagonist depending on its target organs. This hormone play roles in several diseases including breast cancer. There are variety of the relative binding affinity (RBA) of ER and estrogen species in comparison to $17{\beta}-estradiol$ (E2), which is a natural ligand of both $ER{\alpha}$ and $ER{\beta}$. The RBA of the estrogen species are as following: diethyl stilbestrol (DES) > hexestrol > dienestrol > $17{\beta}-estradiol$ (E2) > 17- estradiol > moxestrol > estriol (E3) >4-OH estradiol > estrone-3-sulfate. Estrogen mimetic drugs, selective estrogen receptor modulators (SERMs), have been used as hormonal therapy for ER positive breast cancer and postmenopausal osteoporosis. In the postgenomic era, in silico models have become effective tools for modern drug discovery. These provide three dimensional structures of many transmembrane receptors and enzymes, which are important targets of de novo drug development. The estimated inhibition constants (Ki) from computational model have been used as a screening procedure before in vitro and in vivo studies.

• Journal of the Korean Society of Food Science and Nutrition
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• v.21 no.4
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• pp.381-385
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• 1992

The effect of antioxidant activity of soyasaponin on the liposomal phospholipid membrane were investigated by spectrophotometry. The oxidation index and oxidation rate of ${\alpha}-tocopherol$ containing egg phosphatidylcholine (EPC) liposomes were markedly decreased in the presence of soyasaponin relative to those of purephospholipid liposmes. ${\alpha}-tocopherol$ containing liposomes delayed the oxidation of liposomes. Especially soyasaponin stimulated the antioxidant activity of ${\alpha}-tocopheroal$ in liposomes. These results indicates that soyasaponin in liposomes had some additive effect on antioxidant of ${\alpha}-tocopherol$ toward liposomes.

• Journal of the Korean Ceramic Society
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• v.30 no.10
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• pp.785-790
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• 1993

Sialon ceramics are presently seen as promising materials with high hardness, strength, fracture toughness and corrosion resistance for friction and wear applications. The objective of present work is to improve of mechanical properties and wear resistance of $\alpha$-Sialon(x=0.4) by addition of SiC whisker. $\alpha$-sialon(x=0.4)/SiC whisker composites were obtained by hot-isostatic pressing at 173$0^{\circ}C$ for 1 hour under 1757Kg/$\textrm{cm}^2$ N2 pressure after pressureless sintering the mixture of Si3N4, Y2O3, AlN at 1780~180$0^{\circ}C$ for 3~5 hours in N2 atmosphere. As the amount of SiC whisker content increased, relative density and hardness were decreased, however fracture toughness, bending strength and tribological properties were improved. Tribological properties of $\alpha$-Sialon/15 vol% SiC whisker composite were improved in spite of its low mechanical properties.

• Journal of the Ergonomics Society of Korea
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• v.29 no.5
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• pp.741-750
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• 2010

The objective of this paper is to study if the EEG spectral relative power would be a reasonable measure of expertise level. EEG electrodes were placed on the locations of Fp1, Fp2, F3, F4, T3, T4, O1, O2 while 5 subjects were playing 4 kinds of game on PC. EEG spectral relative power was significantly related with expertise level on the locations of Fp1, T3, T4, O1, O2. And the results showed that the $\theta$ and $\alpha$ activities were decreased, while $\beta$ and $\gamma$ activities were increased. The results indicated that the EEG spectral relative power would be applicable as a quantitative measure of expertise level.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.09a
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• pp.1117-1121
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• 2010

Several isotropic compression-expansion tests and a series of drained conventional traxial tests with various confining pressures for relative density of Beakma river sand 25%, 50%, 80% and 100% selecting Lade's Single Work-Hardening constitutive model. This examination materials use regression analysis as a basis, depending on the relative density of soil parameters change statement attributes. Yield fuction represent the soil parameters h and $\alpha$ is not affected by the changes in the relative density. $\eta_1$ could be replaced by fomula. And Numerical analysis results predicted very good and could confirm that.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1998.11a
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• pp.154-157
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• 1998

This study investigated the psychological and physiological responses to the sound of car horns produced by different. manufacturers. Ten female college students listened to the sound of the horns while their EEG responses on 6 sites were being measured, and rated each hem on psychological scales. Their EEG and psychological responses were investigated as to whether the responses were related to the loudness, sharpness, tonality, and roughness of the horns. The results indicated that the subjects felt more 'dominated' as the loudness and sharpness increased, that the subjects felt more 'pleasant' as the sharpness increased, that the subjects felt more 'dominant' as the tonality increased, and that the subjects felt more 'aroused' as the roughness increased. The physiological results showed that the fast alpha wave in the occipital lobe decreased in the relative power as the loudness, sharpness, and tonality increased, and that the delta wave in the occipital lobe increased and the slow alpha wave in the frontal lobe decreased in the relative power as the roughness increased.