• 대한간호학회지
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• 제31권2호
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• pp.315-327
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• 2001

This was a descriptive study clarifying the factors affecting family caregivers' sense of well-being. This study was conducted with 131 caregivers using structured self-reporting questionnaires and directly interviewing adult patients who had been under treatment in two general hospitals. The hospitals were located in M city from Aug. 10, 2000 until Sep. 2, 2000. The collected data were analyzed using SAS PC+ program, and the data were tested using descriptive statistics, t-tests, ANOVA, Pearson's Correlation Coefficient, and Stepwise Multiple Regression. The results of this study are as follows; 1) The variables affecting the caregivers' sense of burden were age (F=3.76, p=.0063), education level (F=4.67, p=.0015), monthly income (F=2.49, p=.0466), amount of assistance provided (F=4.19, p=.0037), and the relationship with patient before disease (F=9.49, p=.0001). 2) The variables affecting caregivers' sense of well-being were age (F=9.54, p=.0001), residing with patient (t=11.38, p=.0010), the period of caregiving (F=10.52, p= .0001), education level (F= 2.79, p=.0290), monthly income (F=3.04, p=.0196), and relationship with patient before disease (F= 10.51, p=.0001). Also, all of the variables which showed statistical significance. 3) In viewing the relationship between activities of daily living (ADL) and the senses of burden and well-being, a negative relation- ship between activities of daily living (ADL) and a sense of burden was found (r=-.640, p=.000). However, the relationship between activities of daily living (ADL) and a sense of well-being had a positive correlation (r= .232, p=.008). Also the relationship between the sense of burden and the sense of well-being was revealed to have a negative correlation (r=-.614, p=.000). 4) A sense of burden was the most important indicator to the well-being of the caregivers who took care of stroke patients (R2 =.36). In addition to this, living with the patient (45%), activities of daily living (51%), relationship with patient before disease (53%), and the family's monthly income accounted for 56% of the sense of well-being of the caregivers.

• Journal of Korean Medical Science
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• 제33권45호
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• pp.284.1-284.12
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• 2018

Background: Posttraumatic stress symptoms (PTSS) in patients with psychological trauma lead to poor health-related quality of life. Understanding of the relationships among PTSS, anxiety, depression, and illness intrusiveness will guide the development of efficient approaches to enhance subjective well-being in patients with psychological trauma. This study investigated whether anxiety and depression mediate the relationship between PTSS and illness intrusiveness in the hope of providing more comprehensive and effective trauma treatment. Methods: Psychiatric outpatients who visited the trauma clinic of a university hospital (n = 260) participated in this study. Assessments were conducted for PTSS, anxiety, depression, and illness intrusiveness. Structural equation modeling and path analysis were performed to analyze the mediating effects of anxiety and depression on the relationship between PTSS and illness intrusiveness. Results: PTSS had both direct and indirect exacerbating effects on illness intrusiveness. Anxiety exhibited the largest direct exacerbating effect on illness intrusiveness. The indirect effects of PTSS on illness intrusiveness through anxiety alone and through a depression-to-anxiety pathway were significant, but the indirect effect through depression alone was not. Conclusion: The findings demonstrate that anxiety, both independently and as part of an interrelated pathway with depression, partially mediates the relationship between PTSS and illness intrusiveness. Appropriate interventions and a comprehensive approach to alleviate anxiety and depression could mitigate the negative effects of PTSS on illness intrusiveness in patients with psychological trauma.

• 대한간호
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• 제37권4호
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• pp.85-95
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• 1998

Because cancer is not curable, patients who suffer from the cancer disease may have physical, psychological and spiritual problems for the rest of their lives. Especially, when cancer patients do not have the meaning in their lives, they will experience spiritual distress seriously. This study was conducted to provide a basis for nursing intervention strategies to minimize the cancer patients' spiritual distress and understand the relationship between the meaning of life and the spiritual distress in cancer patients. The samples were composed of 62 cancer patients who were inpatients or outpatients of three university hospital and one general hospital in Seoul. Data collection was carried out from January 10,1998 to May 30, 1998. Data were analyzed using a SAS program for descriptive statistic, Pearson correlation, t-test, ANOVA, LSD test and linear regression. The results were as follows; 1. The scores on the meaning of life scale ranged from 20 to 140 with a mean of 94. 16(Standard error: 2.79). 2. The scores on the spiritual distress scale ranged from 13 to 91 with a mean of 62. 29(Standard error: 1.38). 3. There were significant correlations between the meaning of life and the spiritual distress(r=.53. p=.00). 4. The linear regression analysis showed that the meaning of life explained 29% of the spiritual distress. 5. In the degree of the meaning of life and the spiritual distress according to the general characteristics, the level of the meaning of life in cancer patients were different by age(F=3. 42, p=.03), marriage status(F=6.06, p=.00), religion(F=4.21, p=.01), thought about treatment of cancer(F=3.76, p=.04). And the level of the spiritual distress in cancer patients were different by religion(F=7.56, p=.00). In conclusion, the meaning of life was identified as important variable that was contributed to reduce the spiritual distress in cancer patients.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1265-1267
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• 2016

Egg white intake during chemotherapy is common advice for cancer patients for the prevention of leukopenia. However, the benefit is uncertain. We conducted this prospective study to identify the relationship of egg white intake for gynecologic cancer patients who received carboplatin and paclitaxel and the occurrence of leukopenia. Between January 2014 and January, 2015, 81 patients were interviewed regarding their intake of egg whites before receiving subsequent chemotherapy. The basic data, the details of egg white intake and the grade of leukopenia in the previous cycle were recorded. The mean age was 54.1 years and 80% of the patients had a diagnosis of ovarian or endometrial cancer. The patients were interviewed at cycles 1-3 in 45 cases, 4-6 in 45 cases and 7-9 in two cases. Subsequent dose reduction was found in 6.2% and granulocyte-stimulating growth factors was given at 4.9%. All the patients ate egg whites with variations in the number of eggs per day as follows: less than one (3), one to two (56), three to four (14) and five to six (8). Over 70% were recommended by nurses to eat egg whites and about 63% of patients received other supplemental food. Some 44.1% of the patients who ate less than or equal to two eggs per day and 36.4% who ate more than two eggs per day developed grade 2-4 leukopenia, P = 0.61. In conclusion, the data did not provide evidence in support of the conclusion that a greater egg white intake could significantly reduce the occurrence of leukopenia.

• 기본간호학회지
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• 제10권2호
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• pp.171-180
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• 2003

Purpose: The purpose of this study was to investigate the relationship of self-efficacy, knowledge about the disease, and self-care behavior to the metabolic level in patients with NIDDM. Method: Data were collected from March 15 to April 15, 2001. Participants in the study were 48 patients with NIDDM who were seen regularly at the endocrinology out-patient department of Gwangju Christian Hospital. The data were collected through individual interviews and patient blood samples. The data were analyzed with SPSS/PC+, using t-test, ANOVA, Pearson correlation coefficients and Cronbach's Alpha. Result: 1. The mean score for self-efficacy was $71.37{\pm}15.56$, knowledge $15.00{\pm}2.84$, self-care behavior $63.18{\pm}13.10$. The mean score for HbAlc level was $7.66{\pm}1.77%$, HDL cholesterol level, $46.22{\pm}13.04 mg/dl$ and total cholesterol level, $187.93{\pm}41.45 mg/dl$. 2. There was a significant difference between patients with a spouse and those without one (t=-2.08, p=0.042), in knowledge according to level of obesity (t=5.14, p=0.010), duration of illness (t=3.22, p=0.031) and presence of complications related to diabetes (t=-2.58, p= 0.013). There were no significant differences in self-care behavior, but there were significant differences in sugar metabolic level according to sex (t=-2.02, p=0.050). 3. The correlation between diabetic patients' self-efficacy, knowledge and self-care behaviour and metabolic control was significantly related only to self-efficacy and self-care behavior (r=.692, p=0.000). Conclusion: It is necessary to improve self-efficacy, knowledge, and self-care behavior for patients with NIDDM by using nursing intervention programs to promote and maintain metabolic control.

• 한국병원경영학회지
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• 제2권1호
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• pp.65-79
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• 1997

This study aims to measure in-patients' willingness to choose the same hospital, and to define the related factors. The willingness was measured by the fact whether in-patients would return to the same hospital for their future hospitalization and can be said as the essence of ascertaining patients' satisfaction. Data was collected from 236 patients hospitalized in two hospitals selected according to its superiority, one being superior in medical technique, the other being superior in facility and equipment. To enhance the comparability between the two hospitals, the department and the diagnosis were matched, and structured questionnaires were self-fill-up. The main findings are as follows. Hospitals were analyzed by their superiority : medical services, facility and equipment. In case of hospitals with superior medical services, the willingness was proportional to positive doctor-patient relationship, to satisfaction with the medical level, and to the acknowledgement of utility in cure. In case of hospitals with superior facility and equipment, the willingness was proportional to the satisfactory state of overall facility. Two types of hospitals were combined and analyzed. The willingness for choosing hospitals with superior medical services was stronger than that for choosing the other hospitals. The satisfaction with overall facility, satisfaction with medical level, acknowledgement of utility in cure, positive doctor-patient relationship, and better consultation produced higher willingness to choose the same hospital. The willingness for the option shows to what degree the hospital suffices patients' expectation. Patients' understanding views were obviously influential. The satisfaction level for medical aspect was more influential than the level for non-medical aspect.

• Clinical and Experimental Pediatrics
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• 제45권12호
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• pp.1546-1550
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• 2002

목 적: 본 저자들은 VGB과 시야결손과의 관련성을 알기 위해 본 연구를 시행하였다. 방 법: 간질로 진단 받고 VGB을 추가 복용으로 치료를 시행한 환아 중 발달 연령이나 인지 연령이 8세 이상인 환아 78명을 대상으로 하였다. 시야검사는 Humphrey 자동 시야측정계로 시행한 후 결과가 의심이 되면 Goldman 시야측정계로 검사를 즉시 다시 시행하였으며, 이들은 다시 6개월 후에 재검을 실시하였다. 결 과 : 본 연구에서는 78명 중 5명에게 의증이 있었으나 재검시 다시 정상으로 나와 시야결손이 있는 환아는 없었다. 결 론: 본 조사에서 VGB은 시야결손을 일으키는 약물로 나타나지는 않았다. VGB의 시야결손으로 사용에 제한을 두기보다 다른 약으로 조절이 되지 않는 부분발작과 영아연축의 치료에 초기 선택 약물로 조심스럽게 사용하면 무방할 것으로 생각되어진다. 이와 함께 시야결손의 선별검사가 추천되며, VGB을 복용하는 소아에게 있어 정기적인 검사가 필요하겠다.

• Biomolecules & Therapeutics
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• 제16권1호
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• pp.54-60
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• 2008

Dyslipidemia is the multiple lipid metabolic disorders which is one of the high risk factors for the atherosclerotic diseases. It increases the morbidity and mortality and therefore, must be treated with antilipidemic agents. HMG-Co A reductase inhibitors (statins), one of many antidyslipidemic agents, have shown to be significant improvement from the various cholesterol levels. Especially, data from many comparative trials suggest that rosuvastatin is more effective than atorvastatin among many other statins. The aims of this study were to evaluate the efficacy and safety between rosuvastatin and atorvastatin in the treatment of Korean patients with dyslipidemia. Currently the Korean Society of Lipidology and Atherosclerosis based on the Korean health screening data suggests that Korean patients with dyslipidemia should be treated by the target cholesterol levels according to the Adult Treatment Panel III guidelines of the US National Cholesterol Education Program (NCEP-ATP III). We reviewed retrospectively all medical histories of the total 392 dyslipidemic patients with atorvastatin or rosuvastatin from June 1st, 2004 to August 31st, 2006 in Chungbuk National University Medical Center. Patients were classified as total 4 groups by the NCEP-ATP III Guidelines. The numbers of enrolled patients were each 5 mg atorvastatin (n=34), 10 mg atorvastatin (n=148), 5 mg rosuvastatin (n=94) and 10 mg rosuvastatin (n=82). In comparison between groups, rosuvastatin groups in the lowering LDL-C had better efficacies, and the results were each 22% (5 mg atorvastatin), 33.3% (10 mg atorvastatin), 35% (5 mg rosuvastatin) and 41.3% (10 mg rosuvastatin) with the dose relationship (P=0.000). Rosuvastatin groups also have shown to be more significantly reducing Total Cholesterol levels compared to atorvastatin groups with the no dose relationship (P=0.000). In the lowering of non-HDL cholesteroles, rosuvastatin groups showed significantly better efficacies than atorvastatin with the dose-relationship (P=0.000). Each medication groups did not demonstrate the differences in the changing of HDL cholesterol and triglyceride levels (P=0.096, 0.309, respectively). In conclusion, rosuvastatin was better efficacious than atrovastatin in reducing LDL-C Total Chol, and Tg. Therefore, rosuvastatin is a good antilipidemic agents for Korean patients with dyslipidemia and it can use to minimize the morbidity and mortality related to the cardiovascular diseases in Korean.

• 한국콘텐츠학회논문지
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• 제18권8호
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• pp.607-615
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• 2018

본 연구에서는 A치과에 내원하는 환자 중 20-60세에 해당하는 환자 110명을 대상으로 설문조사를 통해 전신질환과 구강건강 간 연관성에 관한 인식 수준과 교육 현황을 파악하였고, 최종 분석에는 92명의 응답을 포함하였다. 연구대상자 중 두 건강상태의 연관성을 인식하고 있는 비율은 48.9%로 나타났다. 또한 연구대상자 중 39.1%는 전신질환과 구강건강의 연관성에 대한 교육을 받은 경험이 있는 것으로 나타났고, 68.5%는 교육이 필요한 것으로 인식하였다. 전신질환과 구강건강의 연관성과 교육 필요성 인식 수준과 관련된 요인을 확인하기 위하여, 로지스틱회귀분석을 실시한 결과 정기적으로 치과를 내원하는 경우 두 질환의 연관성을 인식할 가능성이 3.94배 높았고, 주관적 구강건강수준이 나쁜 경우 교육의 필요성을 인지할 가능성이 5.20배 높았으며, 과거 교육경험 여부는 두 질환의 연관성 인식 및 교육 필요성 인식 수준에 유의한 영향을 미치는 것으로 나타났다. 치과에 내원하는 환자들을 대상으로 치과의료전문가는 교육주체자로서 보다 체계적인 교육방식을 통하여 전신질환과 구강건강 간 연관성에 관한 교육을 필수적으로 수행해야 할 것이다. 이를 위해 치과의료전문가는 진료실 구강보건교육 매뉴얼 및 다양한 매체를 개발해야 하고, 효과적인 교육방법을 모색해야 한다.

• Radiation Oncology Journal
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• 제11권1호
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• pp.143-148
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• 1993

From September 1985 through September 1989,56 patients with stage IIIB carcinoma of the cervix were treated with radiation therapy with curative aim. The overall survival at 5 year was $38{\%}$. The survival rate was better for patients treated with combined external radiotherapy and high dose rate intracavitary radiotherapy than with external radiotherapy alone. No significant survival difference was observed between the unilateral and bilateral parametrial extension of the tumor Seventeen patients experienced recurrence within the irradiated field with a loco-regional recurrence rate of $30{\%}$. Ten patients had complications ($18{\%}$). The complications were mild in three, moderate in four, and severe in three patients. A study was made on the relationship between the fraction numbers of intracavitary radiotherapy, vaginal packing and the complication rate, respectively. In this analysis author observed that the significant treatment factor influencing the survival of cervical cancer was the use of intracavitary radiation, and meticulous vaginal packing could decrease the late complication rate of radiotherapy of cervical cancer.