• Imaging Science in Dentistry
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• v.49 no.4
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• pp.287-294
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• 2019

Purpose: This study was performed to analyze the clinical and imaging features of contemporary osteomyelitis(OM) and to investigate differences in these features on panoramic radiography according to patients' history of use of medication affecting bone metabolism. Materials and Methods: The records of 364 patients(241 female and 123 male, average age 66.8±14.9 years) with OM were retrospectively reviewed. Panoramic imaging features were analyzed and compared between patients with medication-related OM(m-OM) and those with conventional, medication-unrelated OM(c-OM). Results: The age of onset of OM tended to be high, with the largest number of patients experiencing onset in their 70s. The 2 most frequent presumed causes were antiresorptive medication use (44.2%) and odontogenic origin (34.6%). On panoramic radiographs, a mix of osteolysis and sclerosis was the most common lesion pattern observed (68.6%). Sequestrum, extraction socket, and periosteal new bone formation were found in 143(42.1%), 79 (23.2%), and 24 (7.1%) cases, respectively. The m-OM group exhibited sequestrum and extraction socket more frequently and displayed significantly higher mandibular cortical index values than the c-OM group. Conclusion: We observed some differences in imaging features as shown on panoramic radiography according to the history of antiresorptive medication use. This study may help elucidate the predictive imaging features of medication-related osteonecrosis of the jaw.

• Korean Journal of Construction Engineering and Management
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• v.6 no.5 s.27
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• pp.128-138
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• 2005

The success of mergers and acquisitions(M&A) have been evaluated by either measuring ex ante expectations for the specified time period(Window) or assessing long term-based post operating performance (ex post operating performance). In this study, utilizing cumulative abnormal return(CAR) method, M&As which are observed in both domestic and U.S. construction industries were analyzed then research outcomes are compared. Analysis results indicate that stockholders of public construction companies did not realize significant economic gains from M&As. In other words, there was no synergistic gains from the construction M&As. Also, no significant performance difference was observed between related and unrelated diversifications.

• Information Systems Review
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• v.19 no.4
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• pp.171-182
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• 2017

Although economic growth has been retarded since the global economic crisis over recent decades, a large number of firms consider mergers and acquisitions (M and A) as a strategy to survive in a highly competitive market. In particular, an increasing number of firms pursue M and A with IT firms in recent years. In this study, we analyze the post-merger risks measured as ROA volatility for acquiring firms when they seek to acquire an IT firm. Our analysis suggests that a firm with prior experience in M and A acquires IT firms aggressively. Moreover, a substantial number of IT firms are relatively small and unlisted when they are acquired. We also show that an acquiring firm's post-merger risk (i.e., ROA volatility) increases after its acquisition of IT firms. However, an increase in post-merger risk is alleviated when relatedness exists between an acquiring firm and target.

• Korean Management Science Review
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• v.32 no.2
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• pp.91-109
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• 2015

The M&A of firms has been emerged as the effective means of fast diversification and growth in dynamic environment. However, the empirical research about M&A in Korea has not been implemented rich due to the difficulty of obtaining M&A data. In this research, we empirically investigate the relationships among M&A, environment and firms' performance focused on Korean manufacturing firms, understanding the current practice of M&A in Korea. We use the Manufacturing Productivity Panel Survey Data, which are collected by Korea Productivity Center in 2013. The sample size is 575 and the sample is divided into M&A group and non-M&A group. We conduct logit analysis with the independent variables of environment factors (munificence, dynamic, uncertainty), and firms' performance (sales growth, ROS, labor productivity and Inventory turnover), and dependent variable of M&A group or non M&A group. The results show that M&A is closely related to environment feature and firm performance: M&A firms are likely to be the higher munificence and dynamic and the lower sales growth and higher profitability than non-M&A group. In addition, we also examine the characteristics of firms by M&A types (competitors, customer/supplier and firms from unrelated industry). These results imply that if firms confront the pressure of uncertainty (dynamic) and the lower growth, they tend to choose M&A. Futhermore, to profoundly understand the behavior of firms about M&A, it is required to classify the M&A firms by merge types.

• KIEAE Journal
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• v.12 no.2
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• pp.83-92
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• 2012

Recently, many countries are tightening a variety of policies and controls with great efforts to reduce emission of GHGs(Greenhouse Gases) as concern for climate change heightens. The purpose of the study is to provide guidelines for planning and evaluate element and evaluate housing development. The elements are also assorted into 6 sections and 30 planning elements were drawn from them. It is drawn to 6 sections, 27 categories, 31 evaluation elements except cultural and perceptual aspects unrelated to planning elements from these elements. Case analysis has shown that most of planning elements were applied because these cases obtained environment-friendly certification in the country. Followings are the common characteristics. Firstly, it showed that application of planning element in all cases is excellent. Secondly, the case with excellent application of elements related with energy and application degree obtained excellent degree i environment-friendly certification in the country. Finally, application of planning elements related with renewable energy was in poor condition in all cases. With the utilization of SBTool, the evaluation results about planning elements of housing complex of Carbon emissions-reduction type showed that CASE-A obtained 11.17 points and CASE-B obtained 9.24 points. In the case of renewable energy section, it was confirmed that the evaluation doesn't work well. As a result, changes of planning elements affect environment-friendly extent. It was confirmed that accessibility to housing complex of Carbon emissions-reduction type could change. Estimated result of Amount of Carbon emission showed that annual energy consumption per each family of CASE-A is $4,269,964MJ/m^2$, as a result of which, Carbon emission is $234,815kg/m^2$. And annual energy consumption per family of CASE-B is $4,197,563MJ/m^2$, as a result of which, Carbon emission is $214,584kg/m^2$. Application of planning elements in the aspect of housing complex of Carbon emissions-reduction type shows that the level for Carbon emissions-reduction is high level. And study with assessment from the draft should be followed.

• Journal of the korean society of oceanography
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• v.33 no.1-2
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• pp.18-27
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• 1998

Based on 53 quantitative samples collected in April (23 stations) and August (30 stations) of 1993, the species composition, distribution and abundance of macrobenthic invertebrates and bottom characteristics in Chonsu Bay were conducted. Bottom sediments consisted of mud at the close to the dyke, sandymud in the central bay, and coarse sand in the mouth of the bay. A total of 273 species (177 species in April and 200 species in August) were identified. Mean density per sampling station was 480 ind./m$^2$ in April and 1126 ind./m$^2$ in August, respectively. Number of species and densities decreased in the northern part of the bay. The macrobenthos showed a temporal difference in species composition, range of distribution, and community delimitation caused by larval settling. Although during the settling period in summer, large numbers of juveniles added in most of regions, unrelated to environmental conditions, but, successful recruitment may has been a rare event locally Theora fragilis (bivalve), Lumbrineris longifolia(polychaete), Neptys oligobranchia (polychaete) were numerically dominant, but their densities varied seasonally. Community structures of macrobenthos in Chonsu Bay were affected by several bottom environmental conditions, related to tidal current speed, regionally.

• Asian-Australasian Journal of Animal Sciences
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• v.11 no.3
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• pp.293-299
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• 1998

This study was undertaken to measure the concentrations of estradiol-$17{\beta}$, progesterone and testosterone, and to study their relationship with each other and with follicular size in individual buffalo ovarian follicles categorized as small (4 to 5 mm diameter), medium (6 to 9 mm diameter) and large (${\geq}10mm$ diameter). Steroid hormone concentrations varied markedly within follicles of each size category. Estradiol-$17{\beta}$ concentrations (pmol/ml) were positively related to follicular diameter (R = 0.34, n = 308, p < 0.001) and were significantly higher (p < 0.001) in large (1$118.46{\pm}30.25$), compared to those in medium follicles ($50.32{\pm}8.29$) which, in turn were significantly higher (p < 0.001) than those in small follicles ($19.70{\pm}$5.57). Progesterone and testosterone concentrations (pmol/ml) were not related to follicular diameter and were not different among small ($330.99{\pm}27.32$ and $17.68{\pm}2.44$ respectively), medium ($384.84{\pm}26.20$ and $36.47{\pm}4.55$, respectively) and large follicles ($253.25{\pm}32.23$ and $22.57{\pm}4.48$, respectively). Estradiol-$17{\beta}$ and progesterone concentrations were positively related (R = 0.39, n = 47, p < 0.01) in small, unrelated in medium and negatively related in large follicles (R = -0.59, n = 23, p < 0.01). There was no relationship between estradiol-$17{\beta}$ and testosterone concentrations in follicles of all the three size categories. Progesterone and testosterone concentrations were positively related in large follicles (R = 0.57, n = 18, p < 0.02). There was no relationship between the two hormones in small and medium sized follicles. When the follicles with estradiol-$17{\beta}$/progesterone molar ratios of > 1.00 were considered non-atretic, and the rest at different stages of atresia, 197/208(95%) follicles were found to be atretic.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2979-2984
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• 2012

Recent studies have indicated a link between levels of cyclooxygenase-2 (COX-2) and development of the multidrug resistance (MDR) phenotype. The ATP-binding cassette sub-family G member 2 (ABCG2) is a major MDR-related transporter protein that is frequently overexpressed in cancer patients. In this study, we aimed to evaluate any positive correlation between COX-2 and ABCG2 gene expression using the COX-2 inducer 12-O-tetradecanoylphorbol-13-acetate (TPA) in human breast cancer cell lines. ABCG2 mRNA and protein expression was studied using real-time RT-PCR and flow cytometry, respectively. A significant increase of COX-2 mRNA expression (up to 11-fold by 4 h) was induced by TPA in MDA-MB-231 cells, this induction effect being lower in MCF-7 cells. TPA caused a considerable increase up to 9-fold in ABCG2 mRNA expression in parental MCF-7 cells, while it caused a small enhancement in ABCG2 expression up to 67 % by 4 h followed by a time-dependent decrease in ABCG2 mRNA expression in MDA-MB-231 cells. TPA treatment resulted in a slight increase of ABCG2 protein expression in MCF-7 cells, while a time-dependent decrease in ABCG2 protein expression was occurred in MDA-MB-231 cells. In conclusion, based on the observed effects of TPA in MDA-Mb-231 cells, it is proposed that TPA up-regulates ABCG2 expression in the drug sensitive MCF-7 breast cancer cell line through COX-2 unrelated pathways.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.17
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• pp.7223-7228
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• 2014

The MYH11 gene may be related to cell migration and adhesion, intracellular transport, and signal transduction. However, its relationship with prognosis is still uncertain. The aim of this study was to investigate correlations between MYH11 gene expression and prognosis in 58 patients with stage II and III colorectal cancer. Quantitative real-time polymerase chain reaction was performed in fresh CRC tissues to examine mRNA expression, and immunohistochemistry was performed with paraffin-embedded specimens for protein expression. On univariate analysis, MYH11 expression at both mRNA and protein levels, perineural invasion and lymphovascular invasion were related to disease-free survival (p<0.05; log-rank test). Cancers with lower MYH11 expression were more likely to have a poor prognosis. Otherwise, MYH11 expression was unrelated to patient clinicopathological features. On multivariate analysis, low MYH11 expression proved to be an independent adverse prognosticator (p<0.05). These findings show that MYH11 can contribute to predicting prognosis in stage II and III colorectal cancers.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.17 no.2
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• pp.17-22
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• 2003

The priming discharge characteristic at the reset period in the ADS drive method of PDP was experimentally analyzed in this research. The amount of wall charge accumulated by the discharge and the accumulated time are unrelated to the priming pulse width. The self-erase discharge by excessive wall charge is related to the amount of wall charge by the priming discharge and this is related to space charge generated by the priming discharge. From the experimental result, in the optimized priming condition the plus width is 8$mutextrm{s}$ and the voltage is about 163V. The space charge which helps the self-erase discharge exists during about 16$mutextrm{s}$ immediately after generating the priming discharge. Therefore, it is suitable within 16$mutextrm{s}$ of the priming pluse width for the effective reset process.