• Korean Journal of Child Education & Care
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• v.19 no.2
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• pp.117-128
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• 2019

Objective: The purpose of this study is to investigate the effect of mother's acceptance parenting attitude and optimism on children's self-regulation including cognitive, emotional, and behavioral regulation. Methods: The subjects were 361 3, 4, 5 - year - old children and their mothers who attended to the early childhood education institutions. One-way ANOVA was conducted to find out age differences in self-regulation. The regression analysis were conducted to find out whether the mother's optimism could predict their children's self-regulation. The stepwise regression analysis were conducted to find out whether the mother's acceptance parenting attitude could predict their children's self-regulation. Results: As for the self-regulation, there were significant age differences in the cognitve regulation and the behavioral regulation, but not in the emotional regulation. It implies that the abilities of cognitive and behavioral regulation increase as the age level goes up. As for the relations between mother's optimism and their children's self-regulation, only the permanence factor of the mother's optimism predicted children's cognitive, emotional, and behavioral regulation. As for the relations between mother's acceptance parenting attitude and their children's self-regulation, two components of mother's acceptance parenting attitude (unconditionally love & right) could predict children's cognitive, emotional, and behavioral regulation. The component of unique could predict the cognitive and emotional regulation. Conclusion/Implications: These results suggest that mother's optimism and acceptance parenting attitude positively affect on the development of self-regulation ability in children.

• Journal of Cadastre & Land InformatiX
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• v.52 no.1
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• pp.17-36
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• 2022

The purpose of this study is to diagnose problems in the regulation and management of Restricted Development Zone and to prepare a construction plan to convert it to a data-based monitoring system. Unlike other land-use zones, the Restricted Development Zone is a exceptional zone that prohibits all development activities other than the minimum maintenance and must be strictly controlled and managed by the local government. However, the current Restricted Development Zone management is distributed according to the conditions of each local government, and it is not possible to monitor changes in the entire Restricted Development Zone as shown in the survey results. In particular, in this study, by introducing an AI-based monitoring system, MOLIT sends the results of detecting changes across the country at regular time points(monthly and quarterly) to the local governments based on the same regulation standards, and the local governments can be trusted while inputting the regulation results into the system. To propose this methodology, first, a survey and interview were conducted with local government officials and experts. Second, we analyzed cases in which AI analysis was applied to local governments and proposed a plan to improve the efficiency of regulation work according to the introduction of the monitoring system. Third, a plan was prepared to establish a monitoring system based on the advancement of the management information system. This monitoring system can be expanded and applied to land that needs periodic regulation and management in the future, and this study tried to propose a methodology and policy for this.

• Journal of Environmental Impact Assessment
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• v.4 no.2
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• pp.131-149
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• 1995

The object of this study is to suggest some alternatives for environmental management towards sustainable urban development of Chongju city in Korea. This study analyses urban environmental indicators (population density, land use, road, park, car, etc.), level of air and water pollution and solids waste generation by comparing Chongju city and other large cities. Some alternatives towards sustainable development in Chongju city would be summerized and suggested as higher concentrated land use(compact city), mixed land use, supply of mass transit, establishment of regional environmental standards, total emission regulation of air and water pollutants, the preparation of Local Agenda21 of Chongju, and the introduction of strategic environmental assessment(SEA) into environmental impact assessment.

• BMB Reports
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• v.43 no.2
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• pp.103-109
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• 2010

Modification of proteins by the reversible covalent addition of the small ubiquitin like modifier (SUMO) protein has important consequences affecting target protein stability, sub-cellular localization, and protein-protein interactions. SUMOylation involves a cascade of enzymatic reactions, which resembles the process of ubiquitination. In this study, we characterized the SUMOylation system from an important crop plant, rice, and show that it responds to cold, salt and ABA stress conditions on a protein level via the accumulation of SUMOylated proteins. We also characterized the transcriptional regulation of individual SUMOylation cascade components during stress and development. During stress conditions, majority of the SUMO cascade components are transcriptionally down regulated. SUMO conjugate proteins and SUMO cascade component transcripts accumulated differentially in various tissues during plant development with highest levels in reproductive tissues. Taken together, these data suggest a role for SUMOylation in rice development and stress responses.

• Reproductive and Developmental Biology
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• v.30 no.2
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• pp.75-79
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• 2006

The developmental regulation of the preimplantation mammalian embryos is a fundamental step for preparing the implantation and it may be regulated by several autocrine and paracrine factors including platelet-activating factor. PAF improved the embryonic survival and implantation but its role during blastocyst development is still largely unknown. In this study, the effects and the possible pathway of PAF on developmental regulation of blastocyst to hatching stage were investigated. Developmental pattern in hatching embryo was a concentration-response curve showing maximal activity at 1 nM PAF, with decreasing activity at higher concentrations. $50{\mu}M$ 1-(5-isoquinolimnesulfonyl)-2-methylpiperazinme dihydrochloride (H-7), a PKC inhibitor, inhibited the progression of blastocyst to hatching embryo. In addition H-7 blocked the PAF effects on the blastocyst development. Besides tetradecanoylphorbol acetate (TPA), a PKC activator stimulated development of blastocyst to the hatching stage. These finding revealed that PAF support the blastocyst development to the hatching embryo. Also it is suggested that PAF action pathways in hatching supporting include the PKC signaling pathway.

• Molecules and Cells
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• v.39 no.3
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• pp.179-185
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• 2016

Posttranscriptional regulation of RNA metabolism, including RNA processing, intron splicing, editing, RNA export, and decay, is increasingly regarded as an essential step for fine-tuning the regulation of gene expression in eukaryotes. RNA-binding proteins (RBPs) are central regulatory factors controlling posttranscriptional RNA metabolism during plant growth, development, and stress responses. Although functional roles of diverse RBPs in living organisms have been determined during the last decades, our understanding of the functional roles of RBPs in plants is lagging far behind our understanding of those in other organisms, including animals, bacteria, and viruses. However, recent functional analysis of multiple RBP family members involved in plant RNA metabolism and elucidation of the mechanistic roles of RBPs shed light on the cellular roles of diverse RBPs in growth, development, and stress responses of plants. In this review, we will discuss recent studies demonstrating the emerging roles of multiple RBP family members that play essential roles in RNA metabolism during plant growth, development, and stress responses.

• International Journal of Human Ecology
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• v.13 no.1
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• pp.39-56
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• 2012

This study aims at exploring Korean mothers' beliefs on the development of emotion of their children. In specific, sensitivity and maternal reactions to their children's both negative and positive emotion expressions were explored. Further, associations among maternal sensitivity, maternal reactions and child emotion regulation were examined. A total of 100 Korean mothers whose children were between 6 and 7 years old participated in the study. In order to assess mothers' beliefs about sensitivity, vignettes in a forced-choice format were presented through individual interviews. Mothers' self reported reactions to their children's negative emotions and positive emotions and mothers' perceptions of children's emotion regulation were assessed using questionnaires. Results revealed that Korean mothers endorsed both proactive and reactive sensitivity. However, their sensitivity differed depending on the situation. Mothers tended to endorse either Emotion Focused or Problem Focused reactions to their children's negative emotions. Mothers reported that they were most likely to restrict their child positive emotional expression with explanation in supportive way followed by invalidating through reprimanding it. Mothers' reported Distress Reactions and Punitive Reactions to children's expression of negative emotion were associated with children's liability whereas Emotion-Focused Reaction and Problem-Focused Reaction were associated with children's functional emotion regulation. The results are discussed within a theoretical framework of socialization of emotions.

• International Journal of Computer Science & Network Security
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• v.21 no.11
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• pp.189-192
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• 2021

The article is devoted to the issue of the content of legal instruments in terms of tourism business, namely the problems of legal regulation of insurance in tourism. The analysis of the state of development of the problem in question shows that the issue of legal regulation of the insurance contract in general and the contract in tourism services, in general, is insufficiently studied. The article is devoted to topical issues of legal regulation of insurance in the field of tourism, the search for effective mechanisms to increase the liability of both underwriters and insurers. Therefore, insurance can be considered as one of the methods of preventing unfortunate consequences during the implementation of tourism activities. The author's vision of the content of the package of measures that can positively influence not only the development of the tourist industry in general but primarily to help identify those legal segments that need improvement in the future has been stated.

• KIEAE Journal
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• v.16 no.6
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• pp.57-67
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• 2016

Purpose: Laws and regulations of land use are enormous, and the appliance of regulations is overlapped redundantly. Therefore, there are many problems such as time consuming in the process, limiting individual property rights, and interrupting enterprises' economic activities. This study will discuss problems of redundant regulations of land use and its improvement by figuring out current regulations of land use in Gyeonggi-do, one of provinces which applies the most various regulations of land use. Method: This study reviews laws on national land-use planning system and characteristics of land-use regulation in Korea. The extent of the review is limited to "framework act on the regulation of land use" with categories of national land, urban planing, architecture, etc. Through case studies in Gyeonggi-do, the status and problems of redundant regulations of land use are defined. For example, it is overlapped in "Seoul Metropolitan Area Readjustment Planning Act", Development Restriction Zone, Paldang Special District, and so on. It is mainly referred to 2015 Gyeonggi-do land-use restriction map. Result: First, Gyeonggi-do confronts many problems related to the development restrictions and the financial increasement for environmental management by redundant regulations. The development restrictions include supplying additional land for industrial use, relocating colleges, and height limitation relating to military facilities. Second, in order to organize redundant regulations, it is required to combine similar regulations and adjust through communication system among other departments. Third, regulations should consider unique local condition of each district. Lastly, efficient application of regulations is necessary so as to maximize the function of land, protect individual property rights, and stimulate local development.

• Genomics & Informatics
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• v.19 no.2
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• pp.17.1-17.13
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• 2021

Breast cancer is one of the leading causes of cancer in women all over the world and accounts for ~25% of newly observed cancers in women. Epigenetic modifications influence differential expression of genes through non-coding RNA and play a crucial role in cancer regulation. In the present study, epigenetic regulation of gene expression by in-silico analysis of histone modifications using chromatin immunoprecipitation sequencing (ChIP-Seq) has been carried out. Histone modification data of H3K4me3 from one normal-like and four breast cancer cell lines were used to predict miRNA expression at the promoter level. Predicted miRNA promoters (based on ChIP-Seq) were used as a probe to identify gene targets. Five triple-negative breast cancer (TNBC)-specific miRNAs (miR153-1, miR4767, miR4487, miR6720, and miR-LET7I) were identified and corresponding 13 gene targets were predicted. Eight miRNA promoter peaks were predicted to be differentially expressed in at least three breast cancer cell lines (miR4512, miR6791, miR330, miR3180-3, miR6080, miR5787, miR6733, and miR3613). A total of 44 gene targets were identified based on the 3'-untranslated regions of downregulated mRNA genes that contain putative binding targets to these eight miRNAs. These include 17 and 15 genes in luminal-A type and TNBC respectively, that have been reported to be associated with breast cancer regulation. Of the remaining 12 genes, seven (A4GALT, C2ORF74, HRCT1, ZC4H2, ZNF512, ZNF655, and ZNF608) show similar relative expression profiles in large patient samples and other breast cancer cell lines thereby giving insight into predicted role of H3K4me3 mediated gene regulation via the miRNA-mRNA axis.