• Title/Summary/Keyword: Regulation Development

Search Result 2,808, Processing Time 0.028 seconds

Analysis of Safety Decrees for Gas Safety Management System and its Development (주요선진국의 가스기술기준 체제분석 및 제도개선 발전 모형)

  • 김봉진;강경식
    • Journal of the Korea Safety Management & Science
    • /
    • v.3 no.2
    • /
    • pp.51-63
    • /
    • 2001
  • Korea gas industrial because of received LNG in 1987 was converted by the Gas Safety Management System in relation to city gas, LPG and LNG. Gas accident were caused by treatment problem on the supplier and user, on technical and use management mater, on facilities and goods, and included problem with gas safety connection system. This study is present standard application plan of each department to use planning gas technical standard and gas utilization standard of introduction model than statute for change of self-regulation management system and complicated regulation of examination center and order.

  • PDF

Novel $\delta$-Lactam base Histone Deacetylase Inhibitors: Synthesis and Biological Evaluation I.

  • Park, Bum-Woo;Ryu, Dong-Kyu;Kim, Tae-Kyun;Park, Song-Kyu;Han, Jeong-Hwan;Han, Gyoon-Hee
    • Proceedings of the PSK Conference
    • /
    • 2003.10b
    • /
    • pp.184.1-184.1
    • /
    • 2003
  • HDAC and HAT (histone acetyltransferase) are involved in co-regulation in chromatin remodeling and the functional regulation of gene transcription. Abnormal recruitment of HDAC is related to carcinogenesis. Thus, the identification of potent histone deacetylase (HDAC) inhibitor has been considered as very intriguing approach for development for cancer chemotherapy. More recently, anti-inflammatory activity of SAHA cytokines was reported via reduction of proinflammatory cytokinres in vitro and in vivo. (omitted)

  • PDF

Indole-3-Carbinol Promotes Goblet-Cell Differentiation Regulating Wnt and Notch Signaling Pathways AhR-Dependently

  • Park, Joo-Hung;Lee, Jeong-Min;Lee, Eun-Jin;Hwang, Won-Bhin;Kim, Da-Jeong
    • Molecules and Cells
    • /
    • v.41 no.4
    • /
    • pp.290-300
    • /
    • 2018
  • Using an in vitro model of intestinal organoids derived from intestinal crypts, we examined effects of indole-3-carbinol (I3C), a phytochemical that has anticancer and aryl hydrocarbon receptor (AhR)-activating abilities and thus is sold as a dietary supplement, on the development of intestinal organoids and investigated the underlying mechanisms. I3C inhibited the in vitro development of mouse intestinal organoids. Addition of ${\alpha}$-naphthoflavone, an AhR antagonist or AhR siRNA transfection, suppressed I3C function, suggesting that I3C-mediated interference with organoid development is AhR-dependent. I3C increased the expression of Muc2 and lysozyme, lineage-specific genes for goblet cells and Paneth cells, respectively, but inhibits the expression of IAP, a marker gene for enterocytes. In the intestines of mice treated with I3C, the number of goblet cells was reduced, but the number of Paneth cells and the depth and length of crypts and villi were not changed. I3C increased the level of active nonphosphorylated ${\beta}$-catenin, but suppressed the Notch signal. As a result, expression of Hes1, a Notch target gene and a transcriptional repressor that plays a key role in enterocyte differentiation, was reduced, whereas expression of Math1, involved in the differentiation of secretory lineages, was increased. These results provide direct evidence for the role of AhR in the regulation of the development of intestinal stem cells and indicate that such regulation is likely mediated by regulation of Wnt and Notch signals.

Haussmann's Urban Green Space System in Paris' The Efficacities and the Logic of the Green Politics (오스만의 파리시 도심녹지시스템 : 그 효용성과 녹지정책의 논리)

  • 견진현
    • Journal of the Korean Institute of Landscape Architecture
    • /
    • v.31 no.4
    • /
    • pp.1-12
    • /
    • 2003
  • The urban park provides a safe rest and leisure area, and offers the beauty of nature to counter the drearyness of urban space. It can provide benefits such as the reduction of environmental pollution, the regulation of the local climate, and it can also provide a safe area during times of disaster. However, there was no interest in urban park development and control in Korea during the economic boom of the mid 1960s. Furthermore, during the industrialization process, the population grew significantly in the cities and the cities' scales were noticeably extended; as a result of this, the living environment and the natural environment in the cities worsened. With rapid urbanization and industrialization, urban green area diminished, and it became necessary to organize the urban park system to improve quality of life. 45% of south korea's population lives in 6 cities, which is only 4% of Korea's land size. The Urban park system has to be considered in the urban planning process. Paris' urban green system can be a role-model for Korea's urban green development plan to function organically. Urban public park concepts have been used in Paris's urban planning since 1850. There were hardly any parks, gardens and squares for the public before the middle of the 19th century. For improving life-styles for the poor, Napoleon III strongly supported the development of green space systems in Paris by G.E. Haussmann. Napoleon III and Haussmann established and applied the urban green regulation within Paris urban planning. The purpose of this study is to investigate the green regulations Haussmann's Paris urban plan and urban green space system: and as a result of this, it can be an indicator for urban green space development in Korea.

A Study on Software Development and Legal Regulation (소프트웨어 개발과 법적규제)

  • Kim, Hyung-Man
    • Journal of Digital Convergence
    • /
    • v.9 no.5
    • /
    • pp.11-20
    • /
    • 2011
  • Internet users and copyright holder have been at the center of a severe legal dispute because file-sharing soft (P2P) through Napster aggravates the violation of copyright as well as takes on the world. Though it is natural that we should hold users a criminal penalty for the illegal use of various computer programs, I think that if the supply of a computer program is generally within a circle of development act, program developer ought not to hold users criminally liable for the unintended illegal act of users. Two main issues are addressed in this work: (i) the basis and validity of legal responsibility and condemnation that appear in the precedent set as to P2P in America, Japan, and Korea. (ii) the necessity of both scientific technology development and efficient legal regulation of copyright holder. For this purpose, software development and legal regulation are reviewed analyzed from viewpoint of the criminal law.

Studies on the setting a restricted area and recreation fishing management of Jeju special self-governing province (제주특별자치도의 낚시관리 및 통제구역 설정에 관한 연구 -관련법 분석 및 설문조사-)

  • Koo, Myung-Sung;Kim, Suk-Jong
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.50 no.3
    • /
    • pp.385-395
    • /
    • 2014
  • This study is one of the research series for providing basic data that would contribute to the development of the field of fishing industry through the systematic fishing management, protection of fishery resources and healthy fishing culture with safety measures for fishermen in Jeju island according to the implementation of "Fishing Management and Support Act". As a result of analyzing the related acts, the contents of this study are related with provisions of "Fishing management and Support Act" on acts on fishing management, fish bait management, support for fishing and fishing related industries and with provisions of "Act of the preservation and management of desert island" on the preservation, use and development of desert island (use and development in a desert island, behavior in usable desert island). As a result of the survey, the rocks on the seashore showed the highest popularity with 52.6% for fishermen and the seawall was the highest with 47.1% for Maritime police as their fishing place in the fishing related activity data. And as the survey result about the awareness of "Fishing management and Support Act", 65.2% of general fishermen, 36.0% of maritime police and 70.5% of fishing related agencies answered that they knew the act. It was also surveyed whether they consider its contribution to fishing related industry development and positive result was shown by general fishermen and maritime police with 46.8%, 48.0% respectively whereas fishing-related enterprises showed negative answer with 47.7%. In the survey of fishing related regulation standard, general fishermen, maritime police and fishing related agencies all showed different opinions regarding the regulation standard. It is recommended that regulation standard needs to be set up after detailed review.

Comparative Study of US-China Discourse on Cross-border Data Regulation and Cybersecurity: Focusing on ASEAN Development Assistance Cases (미·중 초국경 데이터 규제와 사이버안보 담론 비교: 아세안 개발원조 사례를 중심으로)

  • Kayeon Lee
    • Informatization Policy
    • /
    • v.30 no.1
    • /
    • pp.89-108
    • /
    • 2023
  • Science, technology and innovation (STI) has expanded the activity of actors from the traditional physical territory to the cyberspace. Data-driven platform services and markets advance new discussions on cross-border cooperation and cyber security, as well as discourse on sovereignty in cyberspace. These changes are also affecting the hegemony competition between the US and China. In particular, competition for aid to developing countries that are located along major resource transportation routes, such as natural gas and deep sea resources, is fierce. ASEAN is not only a geopolitical military and security point where the US and China powers collide, but its population of 600 million has great potential for the development of the digital economy due to its data resources. In this regard, this article aims to connect the discourse of liberalism and authoritarianism with data regulation and cybersecurity in international development cooperation, and derive implications for ASEAN integration through this. This study has significance as a convergence study that links international political issues related to big data in terms of global governance.

The Vision of Urban Redevelopment & Reconstruction and the Policy of Deregulation (도시재개발.재건축의 규제완화와 개발사업 "비전")

  • Jeong, Mu-Yong
    • Journal of the Korean Professional Engineers Association
    • /
    • v.41 no.4
    • /
    • pp.24-31
    • /
    • 2008
  • How to do redevelopment & reconstruction project of the old city in the seoul metropolitan policy? Focusing on the vision of future urban development that it will be necessary to divert from problem of regulation to policy of deregulation. After the redevelopment & reconstruction policy is improving as soon so possible that it must be reflected urban development project.

  • PDF

Estimation of the Level of Sustainable Development in Kazakhstan Regions and Recommendation for its Increase

  • Baimukhamedova, Gulzada S.;Nurlanova, Nailya K.;Akhmetova, Sharzada
    • Journal of Distribution Science
    • /
    • v.10 no.7
    • /
    • pp.23-31
    • /
    • 2012
  • The purpose of this study is to investigate existing world economic science theories and concepts of sustainable development as well as create original system of criteria and indicators to assess potential and conditions for sustainable development from a regional perspective and based on the above justify proposals for public authorities to improve methods of economic regulation for regional development. To achieve the goal evolution process of existing theories and concepts of sustainable development and "green growth" have been studied in terms of its adaptation to the spatial development of Kazakhstan, comparative dynamics of natural resources consumption in the Asia-Pacific region and Kazakhstan were investigated as well. Methodology. World best theory and practice methods for assessment of the level of sustainable development of the country and some of its territories were also studied. We selected the best system of criteria and indicators for assessment of economic, social and environmental sustainability of regional systems. Methods offered in this article are based on traditional and new factors of economic development and conditions for operation of regional systems. Indicators are chosen with a glance to basic goals for future development of regions in Kazakhstan. It is recommended to use two levels of methodology offered by author, namely national and regional, and at the local level later (districts, municipalities, cities). The results. Method offered by the author has been tested based on materials and statistics of regions in Kazakhstan. Suitability and usability of the proposed system of criteria and indicators for measuring of economic, social and environmental sustainability of regional systems was proved. Based on this analysis it was found out that there are regions in Kazakhstan that differ from each other by most of key indicators of sustainable regional development and this tendency is increasing. Conclusions and recommendations. As a result of this analysis, the authors have substantiated a number of proposals on methods of analysis to be used, improvement of methods of regional development, implementation of institutional reforms, as well as improvement of regional statistics. This article provides recommendations that can be successfully used in the management practices by public authorities to implement a new regional strategy focused on sustainable development in future.

  • PDF