• Journal of Microbiology and Biotechnology
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• v.31 no.12
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• pp.1643-1655
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• 2021

Recent studies have reported dysbiosis of the microbiome in breast tissue collected from patients with breast cancer and the association between the microbiota and disease progression. However, the role of the microbiota in breast tissue remains unclear, possibly due to the complexity of breast cancer and various factors, including racial and geographical differences, influencing microbiota in breast tissue. Here, to determine the potential role of microbiota in breast tumor tissue, we analyzed 141 tissue samples based on three different tissue types (tumor, adjacent normal, and lymph node tissues) from the same patients with breast cancer in Korea. The microbiota was not simply distinguishable based on tissue types. However, the microbiota could be divided into two cluster types, even within the same tissue type, and the clinicopathologic factors were differently correlated in the two cluster types. Risk of regional recurrence was also significantly different between the microbiota cluster types (p = 0.014). In predicted function analysis, the pentose and glucuronate interconversions were significantly different between the cluster types (q < 0.001), and Enterococcus was the main genus contributing to these differences (q < 0.01). Results showed that the microbiota of breast tissue could interact with the host and influence the risk of regional recurrence. Although further studies would be recommended to validate our results, this study could expand our understanding on the breast tissue microbiota, and the results might be applied to develop novel prediction methods and treatments for patients with breast cancer.

• Journal of the Korean association of regional geographers
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• v.13 no.6
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• pp.639-650
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• 2007

This paper deals with construction of a new administrative city in Naju. This kind of cities are commonly called as 'innovation city' in Korea. This is an experimental regional development program for non-Capital regions. State-owned corporations and public agencies are going to be relocated in the cities. Whether the employees will settle down in Naju with their families is the main research question in this paper. The result of the survey shows that more than half of the respondents are not going to settle down with their families. They are not optimistic about the present and future of the city either. In order to induce in-migration with families, educational environment need to be improved. To help their children to have more chance to talk with native English speakers is one of the examples. Facilities for the illed and the old are also necessary.

• Journal of the Korean association of regional geographers
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• v.17 no.5
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• pp.638-647
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• 2011

Since 2008 the administration of the President Lee Myung-bak is pursuing a new regional policy which differentiates from that of the last administration. It focuses on the maximizing the growth potential of the national territory and suggests the three-tiered regional development system. The paper aims to review the main contents and characteristics of the macro-economic region policy as a representative strategy in a new regional development policy and examine its achievements and the future tasks. Although it is limited to evaluate the accomplishments of the macro-economic region policy due to the short period of time (3 years), it has been successfully recognized that it would be more competitive if regional governments are supporting and connecting each other with neighboring regional governments. In addition, investments to each macro-economic region continue vigorously as planned. In order for the policy to be more successful in the future, however, it is necessary to substantially expand the development project, to systematically construct the governance structure, and to effectively process the industrial plans.

• International Journal of Computer Science & Network Security
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• v.22 no.2
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• pp.334-340
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• 2022

The main purpose of the study is to determine the main aspects of the introduction of modern technologies in the public administration system in the context of globalization. Public administration is inherent in all known models of representation of social systems, characteristic management and other sciences of social management. This allows using the methods and technologies of management, marketing, social partnership and others in public administration and administration at a modern level. One of the main directions of public management and administration is social engineering, aimed at the development and development of the country's social system, and the tool is appropriate technologies. Based on the results of the analysis, the key modern technologies of the public administration system were identified in the context of the impact of globalization.

• Journal of the Economic Geographical Society of Korea
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• v.26 no.4
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• pp.359-374
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• 2023

The main purpose of this paper is to explore the relationship between the transformation of Chinese regional development policy and trends in spatial inequality in mainland China. More specifically, it has attempted to identify the effects of Chinese regional development policies on regional economic inequality by investigating the coefficient of variation and Gini coefficient with GRDP in the province level. Regional inequality in China had increased from 1979 economic reform, but has eased since the 10th Five Year Plan(2001~2005) due to large-scale state investments in the western, central and northeastern regions. However, the analysis is likely to be resulted from the national level. Trends in regional inequality are differentiated in accordance with the eastern, central, northeastern and western regions. For example, regional inequality in the central region has increased, whereas other three regions has decreased since the 10th Five Year Plan. It has played a role in cutting down regional inequality in the national level. In particular, the central region has kept inequality since the 12th Five Year Guideline. It has led to the convergence of the regional economies in the national level. It has stemmed from some limits to greater regional policies in the Central region enforced in the 11th Five Year Guideline(2005~2010).

• International Area Studies Review
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• v.13 no.3
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• pp.73-91
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• 2009

In this paper, we attempt to study the trend of regional disparity among Chinese provinces and examine the effects of globalization on the disparities adapting panel data approach. The panel data set utilized consists of the annual variables of 29 provinces during 18 years from 1990 to 2007. The trend of inter-provincial disparities in the 1990s with the expansive trend but the trend has started to decrease since 2000. The results of the China case study show clearly that the provincial international trade level and ratio variables perform on regional income disparities remarkably in all cases. It means that the large development of international trade do with increased among provincial disparity. While due to the large area in the provinces, there exist urban-rural disparities within provinces could be one of the main source of regional disparities. Therefore, along with western regions development policy various development policies against small cities are necessary for balanced regional economic growth in China.

• Journal of the Korean association of regional geographers
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• v.11 no.4
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• pp.463-475
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• 2005

This paper aims at examining the current states of regional industrial structures, and secondly, analyzing the specialized industries in Youngnam Area, and finally, elucidating its policy implications. The main results of this paper are as follows. The characteristics of specialized industries are different between regions, in terms of static-dynamic dimension, static dimension and dynamic dimension. As a results, the effects of the activating strategies of regional specialized industries are quite different by regions. Therefore, some policy implications are elucidated, as follows. Firstly, different strategy may be committed according to the characteristics of specialized industries. Secondly, the activating strategies of regional specialized industries and regional innovation strategies may be confused considering the changing trends into knowledge based economies.

• Journal of Wetlands Research
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• v.15 no.2
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• pp.159-164
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• 2013

The 4 major rivers restoration project (4RRP) requires the government to invest a lot of money. Regional economic effect is one of the main purposes of implementing the 4RRP. This paper attempts to measure the regional economic effects, focusing on regional employment-inducing effect and regional income-inducing effect. Regional employment-inducing effect is computed by excluding indirect effect and directly investigating the amount of employment. To this end, marginal propensity to consume, household consumption, household income should be derived. We used working day data and government expenditure multiplier to measure local employment creation and income generation. As a result, the project creates 46,628 employments from 2009 to 25 August 2011 and generates 25 trillion won regional income for three years.

• International Journal of Computer Science & Network Security
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• v.22 no.2
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• pp.376-384
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• 2022

The article considers the features of the organizational-economic mechanism of attracting investment resources in the innovative development of regions in terms of sustainable development. Factors influencing the investment activity of regions in terms of sustainable development, including: institutional structure, intellectual capital, level of innovation infrastructure, business development, financial and credit component, level of human resources development, information environment, production development, environmental component. Factors influencing the attraction of investment resources in the regions are identified. The dynamics of changes in the volume of capital investments and foreign direct investment in Ukraine is analyzed. The regional features of the distribution of capital investments in the conditions of sustainable development are revealed. The essence of the main principles on the basis of which the organizational - economic mechanism of attraction of investment resources in innovative development of regions in the conditions of sustainable development should be formed is analyzed. A set of measures to regulate the investment processes of the regions has been identified. The mechanism of attraction of investment resources in innovative development of regions in the conditions of sustainable development is outlined. The results of activity of separate Agencies of regional development for 2020 in the direction of investment and innovation activity and increase of level of investment attractiveness of regions are analyzed. Important prerequisites for the effective implementation of the organizational-economic mechanism for attracting investment resources in the innovative development of regions in terms of sustainable development are identified. The main directions of directing the efforts of the organizational-economic mechanism to ensure the attraction of investment resources in the innovative development of regions in the context of increasing the level of investment activity in the regional aspect are substantiated.

• Journal of Korean Society of Rural Planning
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• v.27 no.3
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• pp.103-116
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• 2021

In this study, the characteristics of rural tourism image perceived by urban residents were analyzed through text analysis of blog data. In order to examine the images related to rural tourism, blog data written with the keyword "Gochang-gun travel" was used. LDA topic analysis, one of the text mining techniques, was used for the analysis. In the tourism image of Gochang-gun, 9 topics were derived, and 112 major places appeared. This was divided into 3 main activities and 5 object spaces through the review of keywords and the original text of blog data. As a result of the analysis, the traditional main resources of the region, Seonun mountain, Seonun temple, and Gochang-eup fortress, formed topic. On the other hand, world heritage such as dolmen and Ungok wetland did not appear as topic. In particular, the farms operated by the private sector form individual topics, and the theme farm can be seen as an important resource for tourism in Gochang-gun. Also, through the distribution of place keywords, it was possible to understand the characteristics of travel by region and the usage behavior of visitors. In the case of Gochang-gun, there was a phenomenon in which visitors were biased by region. This seems to be the result of Gochang-gun seeking to vitalize local tourism focusing on natural, ecological, and scenic resources. It is necessary to establish a plan for balanced regional development and develop other types of tourism resources. This study is different in that it identified the types and characteristics of rural tourism images in the region perceived by visitors, and the status of tourism at the regional level.