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Studies on the Applications of PSL, TL and ESR Methods for the Detection of Dried Fruits and Mushrooms (PSL, TL 및 ESR 분석에 의한 건조과일류 및 버섯류에 대한 검지 특성 연구)

  • Kim, Kyu-Heon;Son, Jin-Hyok;Kang, Yoon-Jung;Park, Hye-Young;Hwang, Cho-Rong;Kim, Jae-I;Lee, Kang-Bong;Jo, Tae-Yong;Eom, Mi-Ok;Park, Sue-Nie;Seong, Rack Seon;Jang, Young-Mi;Lee, Jae-Hwang;Park, Yong-Chjun;Lee, Hwa-Jung;Lee, Sang-Jae;Han, Sang-Bae
    • Journal of Radiation Industry
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    • v.7 no.1
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    • pp.7-14
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    • 2013
  • In this study, we investigated the applicability of the photostimulated luminescence (PSL), thermoluminescence (TL) and electron spin resonance (ESR) methods for various foods. The analysed samples consist of 11 items including dried fruits (6 items) and mushrooms (5 items). To compare between non-irradiated and irradiated food, all samples were irradiated with $^{60}Co$ gamma-ray source. In PSL study, the photon counts of all the unirradiated sample were identified negative (lower than 700). The photon counts irradiated (1, 5, 10 kGy) dried date-palm, dried jujube and mushrooms (Auricularia auricula, Phellinus linteus and Sarcodon aspratus) showed positive (higher than 5,000) and the results for the other samples were negative or intermediate (>700 and >5,000). In TL analysis most of items can be applicable to detect irradiated foods because of showing TL ratio above 0.1. The glow curves by TL method were estimated in the range of $150{\sim}250^{\circ}C$ in irradiated samples. In ESR measurements, the intensity of ESR signal (single-line) increased as the dose of irradiation increased. In particular, the specific ESR signals of irradiation-induced radical were detected in dried papaya, dried date-palm, dried banana, dried pineapple and S. aspratus. According to the results, PSL, TL and ESR methods were successfully applied to detect the irradiated foods. It is concluded that PSL, TL and ESR methods are suitable for detection of irradiated samples and a combined method is recommendable for enhancing the reliability of detection results.

Retrospective Clinical Analysis of Treatment for Primary Warm Autoimmune Hemolytic Anemia (원발성 온난자가면역용혈빈혈의 치료에 대한 후향적 분석)

  • Moon, Hong Seop;Park, Chiyoung
    • Korean Journal of Clinical Pharmacy
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    • v.25 no.3
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    • pp.166-170
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    • 2015
  • Background: Primary warm autoimmune hemolytic anemia (AIHA) is a relatively rare hematologic disorder resulting from autoantibody production against red blood cells. There has been very few studies about primary warm AIHA in South Korea because of its low incidence. We retrospectively analyzed the treatment outcome of primary warm AIHA. Method: We reviewed retrospectively the medical records of 9 primary warm AIHA patients from December 2002 to January 2015. We analyzed the causes and clinical characteristics of primary warm AIHA patients. We retrospectively analyzed the clinical data in electronic medical records for 9 Korean patients with AIHA patients who were diagnosed during the period from December 2002 to January 2015 at the Regional University Hospital in Korea. The study protocol was approved by the Institutional Review Board (IRB #2015-08-007, Chosun University Hospital IRB). Results: The mean age was 52 years (range 27~78), the mean hemoglobin level was 5.0 g/dL (range 2.5~6.4 g/dL). All patients received steroids at therapeutic dosages (corticosteroid 1 mg/Kg) as first line treatment. Eight of them showed complete response (5/8, 62.5%) and partial response (3/8, 37.5%), one patient required second-line treatment with rituximab. Two patients who responded first line treatment were relapsed at 86 weeks and 24 weeks after response, respectively. Only one patient of them was retreated with corticosteroid because of anemic symptoms. Conclusion: This study indicates that oral corticosteroid is an effective therapy for primary warm AIHA.

Functional Characterization and Regional Expression of Dopamine Transporter (도파민 수송체의 기능적 특성 및 발현에 관한 연구)

  • 이상훈;이송득;성기욱;이동섭;이용성;고재경
    • YAKHAK HOEJI
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    • v.39 no.2
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    • pp.161-168
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    • 1995
  • Brain dopamine systems play a central role in the control of movement, hormone release, and many complex behavior. The action of dopamine at its synapse is terminated predominately by high affinity reuptake into presynaptic terminals by dopamine transporter (DAT). The dopamine transporter(DAT) is membrane protein localized to dopamine-containing nerve terminals and closely related with cocaine abuse, Parkinsonism, and schizophrenia. In present study, the recombinant plasmid pRc/CMV-DAT, constructed by subcloning of a cDNA encoding a bovine DAT into eukaryotic expression vector pRc/CMV, was stably transfected into CV-1 cells(monkey kidney cell line). The DAT activities in the cell lines selected by Geneticin$^{R}$ were determined by measuring the uptake of $[^3H]$-dopamine. The transfected cell lines showed 30-50 fold higher activities than untransfected CV-1 cell line, and this result implies that DAT is well expressed and localized in transfected cells. The transfected cells accumulated $[^3H]$-dopamine in a dose-dependent manner with a $K_{m}$ of 991.6nM. Even though high doses of norepinephrine, epinephrine, serotonin, and choline neurotransmitters inhibited the uptake of $[^3H]$-dopamine, DAT in transfected cell line was proven to be much more specific to dopamine. The psychotropic drugs such as GBR12909, CFT, normifensine, clomipramine, desipramine, and imipramine inhibited significantly the dopamine uptake in tissue culture cells stably transfected with DAT cDNA. Radioactive in situ hybridization was done to map the cellular localization of DAT mRNA-containing cells in the adult rat central nervous system. The strong hybridization signals were detected only in the substantia nigra pars compacta and ventral tegmental area. The restricted anatomical localization of DAT mRNA-containing cells confirms the DAT as a presynaptic marker of dopamine-containing cells in the rat brain.

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Multi-dimensional Development Type and Plan for Railway Facility Site - Focus on the Gyeongbu Line Railway Multi-Dimensional Project in Busan (철도시설 부지 입체개발 유형 및 개발 방안 - 경부선 철도 입체화 사업을 대상으로 -)

  • Keum, Yun Jeon ;Kim, Jong Gu
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.43 no.4
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    • pp.525-533
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    • 2023
  • Due to the topographical characteristics of Busan, which has many mountainous areas, there is a shortage of available land, and even the Gyeongbu Line railroad crosses the city center, hindering the disconnection of living areas and urban development. Accordingly, the need for multi-dimensional development has been raised to secure land, and recently, interest has been increasing in connecting cities divided by the undergroundization of the Gyeongbu Line railway and making efficient use of land. In this study, the development type was analyzed through the case of multi-dimensional development of land, and the development direction for each three-dimensional development type was set based on the results of the multi-dimensional development of four areas (Sasang Station, Gupo Station, Gaya Station, and Busanjin Station). In addition, reflecting the regional characteristics of the target area and the ongoing urban regeneration project, we will propose a design plan for horizontal and vertical space utilization of the railway site through multi-dimensional development through the efficient land use.

Distribution of Surface Solar Radiation by Radiative Model in South Korea (복사 모델에 의한 남한의 지표면 태양광 분포)

  • Zo, Il-Sung;Jee, Joon-Bum;Lee, Won-Hak;Lee, Kyu-Tae;Choi, Young-Jean
    • Journal of Climate Change Research
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    • v.1 no.2
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    • pp.147-161
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    • 2010
  • The temporal and spatial distributions of surface solar radiation were calculated by the one layer solar radiative transfer model(GWNU) which was corrected by multi layer Line-by-Line(LBL) model during 2009 in South Korea. The aerosol optical thickness, ozone amount, cloud fraction and total precipitable water were used as the input data for GWNU model run and they were retrieved from Moderate Resolution Imaging Spectrometer(MODIS), Ozone Monitoring Instrument(OMI), MTSAT-1R satellite data and the Regional Data Assimilation Prediction System(RDAPS) model result, respectively. The surface solar radiation was calculated with 4 km spatial resolution in South Korea region using the GWNU model and the results were compared with surface measurement(by pyranometer) data of 22 KMA solar sites. The maximum values(more than $5,400MJ/m^2$) of model calculated annual solar radiation were found in Andong, Daegu and Jinju regions and these results were corresponded with the MTSAT-1R cloud amount data. However, the spatial distribution of surface measurement data was comparatively different from the model calculation because of the insufficient correction and management problems for the sites instruments(pyranometer).

Analytical method of aflatoxins in edible oil and infant-children foods (식용유지와 영유아식품 중 아플라톡신 분석방법)

  • Hu, Soo-Jung;Park, Seung-Young;Kim, Soon-Sun;Lee, Joon-Goo;Song, Ji-Young;Kang, Eun-Gi;Lee, Hyun-Sook;Cho, Dae-Hyun
    • Analytical Science and Technology
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    • v.24 no.2
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    • pp.150-157
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    • 2011
  • Aflatoxins are secondary metabolites of the molds of Aspergillus flavus and Aspergillus parasiticus. They are highly carcinogenic compounds and can affect a wide range of vegetable commodities such as cereals (especially corn), nuts, peanuts, fruits and oil seeds, in the field and during storage. In fact, oilseeds are often stored for weeks in conditions that promote the mould growth, and the possible consequent presence of aflatoxins in oilseeds can lead to their transfer in oil. In addition, aflatoxins can be found as a natural contaminant in multi-cereals and beans making baby food for infants and young-children. The objective of this study was to validate the liquid extraction method or develop an analytical method for edible oil and infant-children foods. Therefore, this study developed condition of extract for aflatoxins ($B_1$, $B_2$, $G_1$ and $G_2$) in edible oil using a high performance liquid chromatography with florescence detector (HPLC/FLD). Aflatoxins were extracted from edible oil samples by means of MSPD (Matrix solid phased dispersion), utilizing $C_{18}$ as dispersing material and purified by using immunoaffinity column. The gression line coefficients were above 0.999. The recoveries for aflatoxins ranged from 85.9 to 93.0%, and relative standard deviations were below 5.7%. The new developed method of aflatoxins effectively enhanced recoveries by using MSPD-Immunoaffinity column compared with liquid extraction. The analytical method for liquid extraction of aflatoxin was appropriate for infant-children food. Reviewing the current method, the recoveries of aflatoxins ($B_1$, $B_2$, $G_1$ and $G_2$) were 89.5~92.3%.

Groundwater Recharge and Discharge in the Urban-rural Composite Area (도농복합지역 지하수 함양과 배출에 대한 연구)

  • Lee, Byung-Sun;Hong, Sung-Woo;Kang, Hee-Jun;Lee, Ji-Seong;Yun, Seong-Taek;Nam, Kyoung-Phile
    • Journal of Soil and Groundwater Environment
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    • v.17 no.2
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    • pp.37-46
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    • 2012
  • This study was conducted to identify groundwater recharge and discharge amounts of a representative urban-rural composite area located in Yongin city, Kyounggi-do, Korea. Groundwater recharge would be affected by mainly two processes in the study area: rainfall and leakage from public water pipelines including water-supply and sewage system. Groundwater recharge rate was estimated to be 13.5% by applying annual groundwater level data from two National Groundwater Monitoring Stations to the master regression curve method. Subsequently, the recharge amounts were determined to be $13,253{\times}10^3m^3/yr$. Leakage amounts from water-supply and sewage system were estimated to be $3,218{\times}10^3$ and $5,696{\times}10^3m^3/yr$, respectively. On the whole, a total of the recharge amounts was $22,167{\times}10^3m^3/yr$, of which 60% covers rainfall recharge and 40% pipeline leakage. Groundwater discharge occurred through three processes in the composite area: baseflow, well pumping, and discharge from urban infrastructure including groundwater infiltration into sewage pipeline and artificial extraction of groundwater to protect underground facilities from submergence. Discharge amounts by baseflow flowing to the Kiheung agricultural reservoir and well pumping were estimated to be $382{\times}10^3$ and $1,323{\times}10^3m^3/yr$, respectively. Occurrence of groundwater infiltration into sewage pipeline was rarely identified. Groundwater extraction amounts from the Bundang subway line as an underground facility were identified as $714{\times}10^3m^3/yr$. Overall, a total of the discharge amounts was determined to be $2,419{\times}10^3m^3/yr$, which was contributed by 29% of artificial discharge. Even though groundwater budget of the composite area was identified to be a surplus, it should be managed for a sound groundwater environment by changing deteriorated pipelines and controlling artificial discharge amounts.

Evaluation of the Construction Plan of Gyeongbuk Cultural Content Promotion Center (경북문화콘텐츠지원센터 설립계획의 평가와 정책대안)

  • Lee, Chul-Woo;Choi, Jeong-Su
    • Journal of the Korean association of regional geographers
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    • v.14 no.5
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    • pp.536-552
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    • 2008
  • In Korea, a variety of policies for the regional cultural industry development have been carried out: the promotion policy of cultural industry cluster, the establishment of cultural industry support center, and the construction of cultural industry complex and the supporting works for the cultural research center. The cultural industry has a dual character of the manufacturing industry and the service industry. The cultural industry of Gyeongbuk province is mostly centered upon small manufacturing firms with low value-added. Thus, it is desperately in need of the building-up of the enterprise supporting system. However, it is difficult to expect that private business service finns can be activated. In this sense, local and regional governments seek to establish so called 'the cultural contents support center'. However, it is not clear whether the center is an organization for the production of cultural contents or an agency for the support of cultural contents industry. Also it does not prepare any major functional introduction facilities and performing programs. Most of all, it is necessary to establish a proper orientation that 'the cultural contents support center' must be not an organization for the direct production of cultural contents, but an organization supporting cultural industry by way of providing cultural industry enterprises with what is necessary for the production of cultural contents. Also, a system for the establishment of business fitting support policy that can cover the whole sectors of cultural industry must be prepared. Furthermore, a synthetic support system for the cultural business associated industries centered on specified sectors such as films, edutainment, and storytelling must be constructed. Finally an environment for the creation and inducement of cultural industry enterprises, and for the active participation of enterprises and related groups in the promotion planning and in the policies of cultural industry must be built along with on- and off-line networks.

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A Study on the Radio-Based Operation Procedures of Switch and Crossing at Branch Line (지선구간의 선로전환기 및 건널목 무선제어 운영절차 연구)

  • Kim, Young-Hoon;Choi, Won-Suk
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.1269-1274
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    • 2011
  • To cut down the maintenance expenses at branch lines, the foreign developed countries have developed the low-cost signalling on low-density lines. These examples are FFB(FunkFahrBetrieb) Radio based train operation by German railways(Deutsche Bahn AG), ERTMS REGIONAL by Europe and LOCOPROL system using a GPS. Also, Korea is developing Information and Communication Technology based low-cost signalling on low-density lines. The characteristics of this system are directly controled switch and crossing by driver. For the purpose of this paper, we reviewed the business process for switch and crossing control. Specially, we compared and analysed both methods whether the driver takes control over the operation procedures of switch or the control message is carried by the command of the controller. And by utilizing the instrument of UML, I planned the switch according to the control authority and the operation procedures needed for the control of crossing.

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Impacts of Changing Environments on Primary Agricultural Cooperatives and Redirections for Its Structural Improvement (단위농협(單位農協)의 환경변화(環境變化)와 조직(組織)의 발전방안(發展方案))

  • Kwon, Yong-Dae
    • Korean Journal of Agricultural Science
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    • v.24 no.1
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    • pp.108-120
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    • 1997
  • Since domestic and international environments has changed rapidly, Korean primary agricultural coopratives are expected to face many difficulties in business management, especially marketing and banking business. Therefore, it is necessary to reframe the exitsting structure of primary agricultural cooperatives so as to enhance the competitiveness in terms of management efficiency. However, There are many problems to be solved such as overnumbered staffs compared with decreasing number of farming population, unbalanced ratio between executive officials and lower-level officials, complexity of position-ranking system resulting from unclearness of official title and office regulations, and management right excessively concentrated on cooperative leader. The suggested measures for such problems are as follows; 1) attaining the economy size of agricultural cooperaitves in line with decreasing rural community, 2) fostering the on-the job training programs and the personnel administration according to job competency, 3) merging the small primary cooperatives into larger units with efficiency, 4) specializing the cooperative business based on their regional comparative advantage, 5) maintaining the rational adjustment between elected cooperative leader's management right and responsibility.

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