• Journal of Life Science
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• v.24 no.7
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• pp.713-720
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• 2014

In this study, the antioxidative and anti-inflammatory activities of Ardisia arborescens ethanol extract (AAEE) were evaluated using in vitro assays and a cell culture model system. AAEE exhibited potent scavenging activity against 1,1-diphenyl-2-picryl hydrazyl (DPPH), similar to ascorbic acid, which was used as a positive control. Moreover, AAEE effectively suppressed lipopolysaccharide (LPS)- and hydrogen peroxide ($H_2O_2$)-induced reactive oxygen species (ROS) in RAW 264.7 cells. Furthermore, AAEE induced the expression of antioxidative enzymes, heme oxygenase 1 (HO-1), and thioredoxin reductase 1 (TrxR1), in addition to their upstream transcription factor, nuclear factor-E2-related factor 2 (Nrf2), in a dose-dependent manner. The upstream signaling pathways of mitogen-activated protein kinases (MAPKs) might regulate the modulation of HO-1, TrxR1, and Nrf2 expression. On the other hand, AAEE inhibited LPS-induced nitric oxide (NO) formation, without cytotoxicity. Suppression of NO formation was the result of AEEE-induced down-regulation of inducible NO synthase (iNOS). The suppression of NO and iNOS by AAEE might be modulated by their upstream transcription factor, nuclear factor (NF)-${\kappa}B$, and activator protein (AP)-1 pathways. Taken together, these results provide important new insights into the antioxidative and anti-inflammatory activities of A. arborescens. AAAEE might represent a promising material in the field of nutraceuticals.

• Journal of Life Science
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• v.24 no.9
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• pp.973-980
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• 2014

This study was conducted to explore new nutraceutical resources from the plant kingdom possessing biological activities. To fulfill this purpose, the anti-oxidative and anti-inflammatory activities of Decaisnea insignis ethanol extract (DIEE) were evaluated. First, DIEE possessed potent scavenging activity against 1,1-diphenyl-2-picryl hydrazyl (DPPH), similar to ascorbic acid used as a positive control. Moreover, DIEE inhibited lipopolysaccharide (LPS)- and hydrogen peroxide ($H_2O_2$)-induced reactive oxygen species (ROS) in RAW 264.7 cells. Furthermore, DIEE induced the expression of an anti-oxidative enzyme, heme oxygenase 1 (HO-1), and its upstream transcription factor, nuclear factor-E2-related factor 2 (Nrf2), in a dose-dependent manner. The modulation of the HO-1 and Nrf2 expressions might be regulated by mitogen-activated protein kinases (MAPKs) and their upstream signaling pathways. On the other hand, DIEE suppressed LPS-induced nitric oxide (NO) formation without cytotoxicity. The inhibition of the NO formation was the result of the downregulation of inducible NO synthase (iNOS) by DIEE. The suppression of NO and iNOS by DIEE might be modulated by their upstream transcription factors, nuclear factor ${\kappa}B$ ($NF-{\kappa}B$), and activator protein 1 (AP-1) pathways. Taken together, these results provide important new insights that D. insignis possesses anti-oxidative and anti-inflammatory activities. Therefore, it might be utilized as a promising material in the field of nutraceuticals.

• Journal of The Korean Society of Agricultural Engineers
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• v.60 no.2
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• pp.37-44
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• 2018

Universal soil loss equation (USLE) had been employed to estimate potential soil loss since it was developed from the statewide data measured and collected in the United States. The equation had an origin in average annual soil loss estimation though, it was modified or improved to provide better opportunities of soil loss estimation outside the United States. The equation has five factors, most studies modifying them to adapt regional status were focused on rainfall erosivity factor and cover management factor. While the conservation practice factor (USLE P factor) is to represent distinct features in agricultural fields, it is challenging to find studies regarding the factor improvements. Moreover, the factor is typically defined using slopes. The factor defining approach was suggested in the study, the approach is a step-by-step method allowing USLE P factor definition with given condition. The minimum condition is slope and field location to provide an opportunity for using in any GIS software and to reflect regionally distinct features. If watershed location, slope, crop type, and mulching type on furrows are given, detailed definition of the factors are possible. The approach was developed from field survey in South-Korea, it is expected to be used for potential soil loss using USLE in South-Korea.

• Proceedings of the KIEE Conference
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• 2004.11b
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• pp.230-233
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• 2004

This paper is proposed that The voltage-dependant power factor model is established as 5th polynomials with convenience data type. This modeling includes the harmonic components by static experiments of individual and composite load. This paper suggested methodology for modeling bus and regional power factor with consideration of harmonics effect by load composition rates and individual load power factor models.

• Journal of the Korean Regional Science Association
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• v.9 no.1
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• pp.45-63
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• 1993

University enrollment has long been regarded as one of the major factors inducing population concentration in Seoul and the Capital Region of Korea. Consequently, since early 1980's increases in enrollment and new establishments of extention universities beyond the boundary of Seoul, has been promoted, while university enrollment quota in Seoul has been strictly controlled. The degree of actual population dispersal, however, resulting from such a university enrollment policy has not been empirically tested. This paper aims at: First, identifying the trend of population growth and evolution process of the university enrollment policy in the Capital Region; Second, comparing the degree of influence of university enrollment on population concetration factors; Third, measuring actual effect of the enrollment control on population dispersal out of Seoul and the Capital Region. Major findings are as follows: First, only a week correlation between population and university enrollment growth trends was found; Second, the relative degree of influence on population concentration in the Capital Region, were order, in the order of magnitude, the physical amenity factor, the socio-cultural amenity factor, the employment climate factor and the educational factor. Third, and most improtant, based on the comparison of spatial distribution of graduated high schools and current residence of the selected university students, the gap between the two distributions was revealed and the inter-regional student population movement was estimated. The result shows that in Seoul's case about one-half of and in Kyunggi Province's case about one-fifth of university enrollment size, contributes to population concentration into Seoul. Fourth, as to the universities outside of the Capital Region, little effect in the case of universities located within the commuting distance, and a little effect on population dispersal in the case of universities located beyond commuting distance, were found. In sum, it seems clear that university enrollment policy in the Capital Region, especially in Inchon/Kyunggi Province has not been effective on student population dispersal out of Seoul and the Capital Region. Therefore, it is strongly recommended that university enrollment policy be throughly re-examined from its goal to the implementation means.

• 한국경영정보학회:학술대회논문집
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• 2007.11a
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• pp.487-492
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• 2007

This research focuses on the development and empirical validation of a model of software piracy behavior on the basis of deterrence theory, expected utility theory and the theory of reasoned action. The total of sample numbered 86 and PLS (Partial Least Square) was utilized for analysis. The test of this study revealed that punishment severity was the greatest significant factor to influence to software piracy and subjective norms was also significantly related to it. However punishment certainty and software cost do not significantly affect to software piracy.

• Journal of Korean Society of Rural Planning
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• v.10 no.3 s.24
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• pp.19-26
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• 2004

In this study, a new model for improving the settlement environment and revitalizing hilly and mountainous areas was presented. A case study was conducted in two rural villages of Nakatsu-Mura in Wakayama-Prefecture, Japan. The settlement environment was evaluated from the point of view of the local residents, and the expectation of the local residents about the regional revitalization of their village in the future was assessed. From the analysis, each factor used far the assessment displayed characteristics of the two rural villages well. The type of improvement in rural villages was classified by a combination of the degree of satisfaction over the current settlement environment and expectation about the regional revitalization of the villages in the future. A method for improving and revitalizing settlement environments was clarified.

• Journal of Korean Academy of Nursing
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• v.45 no.4
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• pp.544-553
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• 2015

Purpose: To investigate the validity and reliability of the Korean Version of the Assault Response Questionnaire (ARQ-K) measuring the intensity of reaction to victimization of emergency nurses in Korea. Methods: An internal consistency reliability and construct validity using exploratory and confirmatory factor analysis were conducted using SPSS WIN (20.0) and AMOS (20.0). Survey data were collected from 321 nurses who worked in 3 levels - wide regional emergency centers, regional emergency centers, appointed emergency centers - of emergency care facilities in Busan, Korea. Results: The Cronbach's alpha values regarding internal consistency were .77~.93 for the subscales of ARQ-K. Factor loadings of the 26 items on the four subscales ranged from .59 to .84. The four-subscale model was validated by confirmatory factor analysis (${\chi}^2/df=3.85$, p<.001, RMR=.06, GFI=.80, NFI=.81, TLI=.83, CFI=.85, RMSEA=.09). Conclusion: This study shows that the Korean Version of the Assault Response Questionnaire is a valid and reliable instrument to assess nurses' reaction to victimization of emergency nurses in Korea.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.50 no.7
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• pp.303-308
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• 2001

This paper presents algorithm to plan construction and expanding of substation considering contingency accidents by proposing utilization factor according to configuration of substation bank system. In this paper, firstly, proper sphere of supply area by each district which could be standardized with respect to its supply capacity is established under assumption of long term load forecasting. Secondly, goal of utilization ratio based on configuration of substation bank was set to keep reliability by remaining sound bank when it happen to one bank accidents. Finally, it is set up for optimal construction and expanding of substation considering economy and reliability simultaneously about substation to exceed these ratio. To verify proposed algorithm, at first, after adopting a part of Kangnam area in Seoul as area for testing, it is divided into several regions for this area according to power branches of power utility. Secondly, by deriving correlation factor between load demand and economic indicators in these region respectively, the regional load forecasting was performed with economic growth and city plan scenario. Finally, based on the predicted load demand by region and land use data which is identified from air-photographic, the load demand by district was predicted. Also, planning for substation considering contingency is formulated to expand taking into account computing utilization factor which is based on configuration of substation bank respectively.

• Journal of the Korean association of regional geographers
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• v.15 no.2
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• pp.226-249
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• 2009

This study aims to establish the regional mix types and models of place marketing strategy. For this purpose, eighty seven cases of place marketing in Gwangju-Jeonnam region during the last two years are reviewed, Twenty seven types of regional mix are abstracted according to space, theme, subject, target, and factor. There are five spatial types(urban mix, zoning mix, zoning urban mix, package urban mix, zoning mix, and space package mix), eight thematic types(culture mix, history mix, tourism mix, industry mix, administration mix, environment mix, transportation mix, and PR mix), five subject types(central government led public mix, local government led public mix, enterprise led private mix, civil society led private mix, and private public partnership mix), four target types(resident mix, tourist mix, enterprise mix, and common mix), and five factor types (organization mix, image mix, point mix, target mix, and channel mix). In the basis of these types, the twenty two primary model of regional mix, and the one hundred twenty six secondary model of regional mix are established.