• Journal of the Korean Society for Marine Environment & Energy
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• v.12 no.4
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• pp.284-288
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• 2009

The International Convention for the Control and Management of Ships Ballast Water & Sediments was adopted by consensus at a diplomatic conference of IMO at 2004. To prepare the Ballast Water Management Convention, fundamental technologies such as treatment system, type approval, risk assessment and various technical informations for formulation of the regulation for national strategy shall be developed. The information item of voyage and discharge of ship's ballast water are gathered by visiting vessel and agent at port. Using the 97 results by ships type characteristic analysis on the relation between loading/unloading and discharge/uptake of ballast water, the amounts of discharge/uptake of ballast water at each port and all of country in Korea are predicted. Hence, It is apparent that the uptake of ballast water is predicted to about 70 million ton in total of Busan, Incheon, Kwangyang and Ulsan ports at 2006 which is over 3 times than discharges.

• The Journal of Korean Academic Society of Nursing Education
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• v.2
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• pp.32-55
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• 1996

It was enacted 'Emergency Medical Act' in January, 1994 beginning the emergency medical service system from 1982, and while it was established the emergency medical department in junior college providing the detailed agenda about emergency medical technician and the regulation relative to the application of a law on the emergency medical act in 1995, the fire school and the National Medical Center are enforced the curriculum. It is very important subject faced for the construction of emergency medical system to produce a number of emergency medical technicians to be sufficient to the role of emergency aid. In this study it is analysed the training curriculum for the emergency medical technician and presented the improvement plans. 1. Though it needs the qualification level of first and second class in the selection process, the more important thing needs the detailed qualification level by term of one's service and the skills of business accomplishment. 2. In the examination management, (1) written examination is composed of the questions to understand how much faithfully they carry out the practical business as the emergency medical technicians, (2) it is added practical examination as the item to appraise the situation disposal ability. 3. It is necessary to prescribe the activity in the medical institution and ambulance arrangement through the development of 'Business Treatment Guide'. 4. For the regional balanced disposition of emergency medical personnel it is selected balanceably the educational institution by eight medical service areas, and considering the characteristics of region it is necessary to manage, in the practical business training course, another special course such as the mountains medical aid and sea medical aid. 5. In the period of education the first class needs the practical business training period of a certain period after passing examination, and the second class needs the extension of the period. 6. As the problems to improve in the curriculum [1] in the first class course (1) intensification of practical educaiton (2) reinforcement of curriculum (3) the development of standardized curriculum etc., [2] in the second class course (1) varieties of curriculum (2) intensification of basic first aid treatment education.

• Journal of Society of Preventive Korean Medicine
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• v.6 no.1
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• pp.36-50
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• 2002

Health industry, a knowledge based high value-added industry, is being considered as a strategic area for the 21C and many advanced countries are making every endeavors for the promotion of health industry along with information technology, new materials, and mechatronics. Korean health industry, however, has been excluded from the governmental supports as well as bound by strict regulation so far, and there is a significant gap in technology compared with advanced countries. In 21C, technology is the main factor of national competitiveness and that is why the role of R&D institutes are so important in the high level of competition to cope with the technology protection policies of advanced countries. In this article, with Directory of Korean R&D Institutes published by Korea Industry Technology Association, I reviewed the trends of R&D institute of health industry. Main findings of the research can be summarized as follows. The portion of health industry R&D institute is 3.6% of total R&D institute but the amount of R&D investment is over than 5% This means health industry are knowledge based and R&D intensified industry, meanwhile the variations of same industry R&D institutes of health industry is huge in R&D investments and other activities. Regional distributions of health industry institutes show some kind of different patterns in each industry areas. Medical devices and Medical informatics's preference of metropolitan region are distinguished with other industry areas. Many of the institutes are located in same site of it's company rather than operating separate building for R&D specific uses. It is better for transforming ideas to products and close cooperation of research body with product lines, but it is a handicap for networking and communicating with other research institutions too. It takes 18.4yrs for bearing R&D institute on the average. For a long times 'copy products' or 'me too products' policies were easy way to maintain business entities. But recently, it is recognized that research activities are essential component of sustaining it's own business firms. This means technology itself is leading power of corporation itself in the high level of competition.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.38 no.2
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• pp.155-163
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• 2014

At gas stations, liquid fuels expand and contract in volume owing to temperature variations. In Korea, the ambient temperature varies between $-15^{\circ}C$ in winter and $35^{\circ}C$ in summer. The volume expansion coefficients of liquid fuels are about $0.1%/^{\circ}C$. To investigate this issue, we measured daily changes in fuel temperature and the delivered fuel temperature at gas stations. In addition, we scrutinized the daily, monthly, and annual changes in temperature over past 50 years in Korea. The results show that the temperature of the fuel in the storage tank was maintained at a stable value(summer or winter). Many factors, such as the surrounding conditions, fuel filling frequency, and gas station location, influence the delivered fuel temperature. The results of this study can be applied for establishing a national regulation and will contribute to fair transactions.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.19
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• pp.7-31
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• 2003

The governments of almost countries have the rules and procedures that the purchasing entities have to follow, in order to ensure that the best value for money spent is obtained in procuring goods and services. However, there are often some of important problems in their rules relating to government procurement. Namely, almost countries have a variety of discriminatory regulations for foreign suppliers in the government procurement laws with the object of national security, economic welfare, and protection of domestic market from international competition. For this reason, several advanced countries had reached the Plurilateral Agreement on Government Procurement during Tokyo Round(1973-1979) and Uruguay Round(1986-1994). However, the provisions of two agreements do not apply to all products made by the government but only to those made by purchasing entities specified by each member country in its list in the Appendix. Accordingly, the size of goods and services purchased from foreign suppliers were comparatively not large. As we know well, the United States have spent a large amount of money from federal and state government budget. But the portion of procurement from foreign suppliers is still small, compared with the portion of procurement from domestic suppliers. The main reason are that U.S. has applied for long time the so-called Buy American Act to government procurement positively and maintained many kinds of other domestic regulations which have discriminatory provisions for foreign goods and foreign suppliers. On the recognition of these points, this thesis deals with the Buy American Act and other U.S. domestic laws, regional and bilateral, and plurilateral agreements including WTO Agreement on Government Procurement. As a result, the author found that there are several concerns and problems in the U.S. regulations relating to government procurement. It include the provisions on priority procurement of U.S.-produced products, local contents requirements, set-aside procurement from small business, and exclusion of preferential procurement from the developing countries.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.21 no.4
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• pp.227-235
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• 2011

The objective of this study was to analyze 157 processes of 145 industries that exceeded Korean Occupational Exposure Limits (KOEL) for carcinogen during the 11 year period from 1999 to 2009. The data included number of industry and workers exposed, type of carcinogen and their exceeded ratio, type and size of industry in each year. These data were collected by 46 regional employment & labor offices in Korea using work environment monitoring reports. The result showed that, in each year, about 10 industries exceed their carcinogen exposure limit. The most common carcinogen exceeding KOEL were found to be formaldehyde, benzene, ethylene oxide and chromium VI. The carcinogen with the highest level of over-exposure were in the order of formaldehyde, benzene, ethylene oxide and asbestos. Fabricated metal product manufacturing industry were found to be most vulnerable against carcinogen with 11.1% of them exceeding carcinogen KOEL followed by electronic components manufacturing industry (8.3%), chemical products manufacturing industry (6.3%), and electrical equipments manufacturing industry (4.9%). The industry employing less than 50 workers had the highest percentage of exceeding carcinogen KOEL with 52.8%. The result also showed that strengthening KOEL for benzene and asbestos helped reduce the level of carcinogen over-exposure. Based on these results, strengthening the KOEL or new regulation turned out to help reduce the carcinogen over-exposure level. Benzene, ethylene oxide and chromium VI were the most frequently over-exposed carcinogen with the highest level. Therefore, these chemicals need to be regulated with a highest priority to improve the workplace environment. The results also show that the small-sized industries employing less than 50 workers was the most vulnerable against carcinogen exposures. Therefore, more government support are needed for these small-sized industries to help them to improve their workplace environment.

• Korea Journal of Hospital Management
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• v.8 no.4
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• pp.1-25
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• 2003

The wave of globalisation initiated by marketisation has increasingly penetrated into all sectors across the world, accordingly, the health & hospital service sector could not be made no escapes, and it currently faces the order of more marketised competition more than ever. Traditionally, the characteristic of the hospital services in the UK has considered as a model of social provision by government. However, contrary to our knowledge, the sphere of the hospital service in the UK has already been immersed in by the marketisation, in which the private actors have been embedded in order to tweak the activities of the hospital service with in the European Union. As the methodology of this research, the qualitative analysis, namely the interview with some doctors in Surgery, NHS Trusts staffs and relevant specialists in has been performed on April to May, 2003. And on the other hand, the various documents related to its service have been analysed. Thus, this paper will review the characteristics of the health service sector in the UK. In doing so, it will illuminate what would be the structural factors derived from its existing system, as a result, it will shed light on how the UK government makes an effort to resolve the problematic situation by reviewing the policy direction of Foundation Hospital proposed recently. In the next stage, it will analyse how all elements consist of the hospital management in the UK has been adjusted and be likely to be changed within Europe. More specifically focuses on how the private hospital service has been managed and related with the activities of its public hospital service-NHS Trusts. Also, under the circumstance, what private health insurance companies function will be studied. In conclusion, it will be concluded that what will be the implication of Korean hospital service market so as to correspond to globally open market by WTO. Now the UK health service system has faced a turning point of becoming more health care market internally and externally pressed by global and regional factors. Thus it is meaningful to scrutinize how a key part of social provision in the health care market system tends to adjust to globally marketised regulation.

• Biomedical Science Letters
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• v.11 no.3
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• pp.365-373
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• 2005

The aim of this study was to investigate the alterations in meningeal blood flow by stimulation of trigeminovascular system. An open cranial window was prepared on the right parietal bone of male Sprague-Dawley rats. Trigeminovascular system was stimulated by electrical stimulation of trigeminal ganglion (ETS), somatosensory (whisker) stimulation, or topical applications of capsaicin and neuropeptides including substance P and calcitonin gene-related peptide (CGRP). Neonatal capsaicin pretreatment was performed with subcutaneous administration of capsaicin (50 mg/kg) within the first 24 hours after birth. Changes in regional blood flow of dural artery (rDBF) and pial artery (rPBF) were continuously measured through the cranial window by laser-Doppler flowmetry. Both ETS and capsaicin caused a chain of alterations in rPBF and rDBF responses, i.e., an immediate transient decrease followed by rapid and marked increase in rPBF, which were significantly attenuated not only by pretreatments with L-733,060, a $NK_1$ receptor blocker, $CGRP_{8-37}$, a $CGRP_1$ receptor blocker, and 7-nitroindazole monosodium salt (7-NINA), a neuronal nitric oxide synthase inhibitor but also by neonatal capsaicin treatment. Exogenous neuropeptides including substance P and CGRP increased the meningeal blood flow, which was significantly attenuated not only by pretreatment with L-733,060 and $CGRP_{8-37}$, respectively, but also by pretreatment with 7-NINA. The rPBF response to whisker stimulation was significantly attenuated not only by trigeminovascular system injuries including nasociliary nerve denervation and neonatal capsaicin treatment but also by pretreatments with L-733,060, $CGRP_{8-37}$ and 7-NINA. These results suggest that the stimulation of trigeminovascular system causes prominent alterations in meningeal blood flow, and that neuropeptides as well as nitric oxide in the trigeminovascular system are importantly implicated in the regulation of meningeal blood flow.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.16 no.6
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• pp.49-62
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• 2013

As ten years have passed since national parks were adjusted and released inceptively, it is the time for evaluating the effectiveness of the national park policy and improving it on the basis of the evaluation result. In this study, the method of appraising the environmental and socio-economical ripple effect on the implementation of national park regulation were provided, based on the institutional consideration, the environment analysis, the survey of residents consciousness, the statistical analysis and so on. It is applied to target sites where were released from national parks, and the policy direction was suggested for sustainable use and management of national parks. National parks, that exhibit various characteristics depending on geographical and local conditions, were categorized through the statistical approach. Released sites from Seoraksan National park, where was categorized as the core national park for sustainable use and management, were evaluated environmentally based on the time-series analysis of environmental thematic maps and socio-economically based on the survey on residents perceptions. As a result of this study, the environmental effect of released sites has been declined or threatened, and the residents' economic, social and living condition in these areas are still not improved(p<0.05) since the adjustment of national parks. Based on the policy approach reflecting regional characteristics, natural resources are kept and enhanced for the sustainable use and management of national parks. And a consensus on the national park policy of national park should be developed between local residents and voluntary participation and public awareness should be attracted from them, based on the construction and the supplement of the infrastructure.

• Molecules and Cells
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• v.28 no.2
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• pp.119-124
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• 2009

Anti cancer agent 5-FU (Fluoro Uracil) is a prodrug that can be metabolized and then activated to interfere with RNA and DNA homeostasis. However, the majority of administered 5-FU is known to be catabolized in vivo in the liver where Dihydropyrimidine dehydrogenase (DPD) is abundantly expressed to degrade 5-FU. The biological factors that correlate with the response to 5-FU-based chemotherapy have been proposed to include uridine phosphorylase (UPP), thymidine phosphorylase (TPP), p53 and microsatellite instability. Among these, the expression of UPP is known to be controlled by cytokines such as $TNF-{\alpha}$, IL1 and $IFN-{\gamma}$. Our preliminary study using a DNA microarray technique showed that basic fibroblast growth factor (bFGF) markedly induced the expression of UPP1 at the transcription level. In the present study, we investigated whether bFGF could modulate the expression of UPP1 in osteo-lineage cells and examined the sensitivity of these cells to 5-FU mediated apoptosis.