• Journal of architectural history
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• v.7 no.4 s.17
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• pp.175-190
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• 1998

The formation of Chinese Town in Malacca of Malaysia and Singapore would explain that Chinese gradually played an important role of commerce and urban service according to the Western European advance to southeast Asia and the construction of colonial cities from the 16th century to 19th and massed residence in many cites of southeast Asia. Chinese was usually separated from the Western European by western colonial policy and city planning. Common architectural characteristics in Chinese towns of Malaysia can refer to the transmission of the Chinese architectural material, the combination of dwelling and commerce in a house and the space organization centered on a court or an air well in the narrow and long site, lying adjacent to street etc. The Chinese dwellings in Malaysia rooted with Chinese settlement in southeast Asia. The Chinese dwellings was not always a shop on 1th floor and a dwelling on 2nd floor before the 19th century. But as Chinese immigration and commercial activity progressed in earnest in the early of 19th century, the row house of Chinese for dwelling was autonomously changed to two functional shophouse for dwelling and commerce. Chinese row house can refer to the use of Malay regional material, change of symmetrical Chinese traditional housing type by the narrow and long site and the tendency of the eclectic elevation of Western and China. Another architectural characteristics of the shophouse is an appearance of the continuous verandah with a cover regulated by Stamford Raffles in Singapore. This regulation was applied to architecture in Chinese Town as Stamford Raffles constructed Singapore. It was spread to South China reversely and became the regulation of streetscape for the modern city. Shophouse of Chinese towns in Southeast Asia and south China can be understood by context of Chinese immigration, colonialism, housing type of commerce and dwelling and the Western European city planning.

• Journal of the Korean Institute of Landscape Architecture
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• v.35 no.4
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• pp.1-15
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• 2007

The purpose of this study is to mate a basic foundation for the discourse of Koreanness of contemporary Korean landscape architecture by way of searching the conceptual definitions of Koreanness through analysis of Koreanness discourses. The results are that discourses of Koreanness are to be classified in aesthetics type, spatial-temporal type, and cultural type. Aesthetics type is understood as style in terms of formal and design representation planning principles of spatial composition and immanence in terms of philosophy. Spatial-temporal type is understood as contemporaneity. This is classified as the concept of connoting of tradition, and separating and keeping a distance from tradition. Cultural type is prescribed as cultural identity. This is classified as unity, generality and individuality. The intension of Koreanness of these types is represented as an aspect changing and shifting from one regulation to another regulation. First, in the concerns of substantial archetypes like Korean original form, decorative element, spatial composition aesthetic perception and philosophy, Koreanness shifts to the point of view of contemporaniety which is created and defined in history. Second, Koreanness as contemporaniety shows a trend of shifting the point of view which is to be found through the reconsideration on modem history and modernism. Third, Koreanness defined as cultural identity shows a trend to emphasize the differences in other cultures and includes all the modem cultural agents. The number of views understood as individuality and denial are small but provide important points. Programmatic definition of Koreanness is not suitable. This basic study uses a stipulative or operational definition of Koreanness in many ways such as spatial and regional identity. Koreanness study for Korean contemporary landscape architecture requires a systematic understanding of modernity and colonization relating to identity. Also, it is needed to elaborate on the discourse to divide the meaning of a concept of identity.

• The Journal of the Korea Contents Association
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• v.12 no.2
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• pp.517-531
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• 2012

This study was aimed to propose a framework for the design and implementation of a competency-based curriculum for higher education institutions. For achieving the purpose, surveys were conducted with 300 companies at the southern regional area to find out core work-competencies that are needed in the work places. In addition, general education curriculum from 4 universities from the same area were analyzed and compared with the survey results to examine if the university curriculum satisfy the need of work places by providing courses that nurturing work competencies. The study found that abilities to work as a team and self-regulation are the core competencies. However, the participating universities did not provide enough courses for students to achieve the core work competencies that are mostly needed in the work places. Based on the study results, the competency based-curriculum were suggested, and the process for implementing the curriculum was discussed.

• The Korea Journal of Herbology
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• v.31 no.1
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• pp.17-23
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• 2016

Objectives : This study was designed to protect effect on atherosclerosis through regulation of low density lipoprotein(LDL) by 70 % ethanol extract Ganoderma lucidum (GL) in LDL receptor knockout mouse (LDLr ko mice) fed Western diet.Methods : The LDLr ko mice were divided into 3 groups ; Control, GL100, and GL300. After grouping, LDLr ko mice were fed Western diet. The GL (100 or 300 mg/kg body weight/day, p.o.) was administered every day for 8 weeks. The body weight and food intake were measured every day. The changes in the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine, triglyceride (TG), total cholesterol (TC), and high-density lipoprotein (HDL) in serum were analyzed after experiment.Results : The LDLr ko mice fed Western diet were increased body weight gain and blood biochemistry parameters such as ALT, AST, TG, TC, and LDL. However GL300 group significantly reduced the body weight. Also TG, TC, and LDL level did not increase. The levels of ALT, AST, HDL were not changed. Also, LDLr ko mice model liver were observed lipid drop, but GL groups did not appear. Futhermore, histological analysis of GL groups aorta tissue were similar to NOR groups.Conclusions : We confirmed that whether GL administration is protect atherosclerosis or not. As the results, blood biochemistry and histological analysis did not changed much in GL administration groups. This study provides scientific evidence that GL protect the atherosclerosis through the reduction of LDL cholesterol. Therefore GL has potential medicine inhibition of atherosclerosis.

• The Korea Journal of Herbology
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• v.31 no.1
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• pp.25-31
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• 2016

Objectives : The present study was conducted to evaluate protective effects of Combined Extract of young persimmon fruit and citrus peel (PCM) in Reflux Esophagitis(RE) rats.Methods : Twenty-four Sprague-Dawley (SD) rats were divided four groups and each group had six rats ; Normal group, RE control group, RE group treated PCM 50 ,100 mg/kg body weight group. Reflux esophagitis was induced that tied the pylorus and fundus in SD rats stomach. PCM was administered at 50, 100 mg/kg body weight 2 hrs prior to induction of RE. After 6 hrs, the effects of PCM treated rats were compared with those of normal and control rats. We have performed an analysis such as pH of stomach secretion, oxidative stress biomarkers in serum, and western blot.Results : The increased esophageal mucosa damage by RE was markedly improved by PCM treatment in a dose-dependent manner. Also, the administration of PCM decreased the elevated serum reactive oxygen species (ROS) and peroxynitrite (ONOO^-) in serum. The protein expressions of anti oxidant such as SOD, catalase, GPx exhibited down-regulation by PCM treatment in tissues. And, PCM effectively reduce inflammatory cytokines such as inflammation-related proteins cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), Tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) in RE rats. In addition, NFκB and p-IκBɑ were decreased in PCM-adiministrated RE rats. But there was no difference on stomach secretion pH between reflux esophagitis rats and PCM administration rat group.Conclusions : In conclusion, administration of PCM (50, 100 mg/kg body weight) made esophagus have less inflammation and injury by decreased NFκB path way. These findings suggest that PCM could have Improving effects on reflux esophagitis.

• Journal of the Economic Geographical Society of Korea
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• v.15 no.4
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• pp.457-463
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• 2012

This study examines the epistemological approach of the economic geography and the approach in the ontology of geography which has been studied based on the region, and thereby aims at the systematization of economic geography. Since 1956, Korean economic geography study has been conducted under the development of studies in developed countries without discussing the uniqueness of the study or the systematization of the research approaches. As a result, the systematization is built after the economic geography is divided into neoclassical economy, geographical political economy, regional structure of the national economy, and local autonomous entity economy on a axis of epistemology and ontology for the systematization of approaches. We should pursue the intellectual change adding the major economic phenomena theories such as the world-system perspective, the regulation theory, network theory, and the institutionalism etc. into the systematization of the economic geography.

• Journal of the Economic Geographical Society of Korea
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• v.12 no.2
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• pp.215-233
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• 2009

The purpose of this study is to compare traditional productivity and environmental productivity of Chinese 28 provinces for 1997-2005. The Eastern, the Central and the Western regions show higher M productivity indices than ML productivity indices before 2000 year, but two productivity indices of three regions report almost similar levels after 2000 year. The M productivity indices were higher than the ML productivity indices in the most provinces for 1997-2005. It implies that the Chinese regional economies have difficulties in the production activity reducing pollutants and increasing desirable outputs simultaneously. In the future, the Chinese 28 provinces need to change the direction of economic growth in the way that pursuits economic growth restraining pollution emission quantities thoroughly and should improve the concrete investment for clean technology of pollutant treatment, reinforcement of environmental regulation, and effectiveness of enforcement law.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.12
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• pp.4965-4969
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• 2015

LCN2 (Lipocalin 2) is a 25 KD secreted acute phase protein, reported to be a novel regulator of angiogenesis in breast cancer. Up regulation of LCN2 had been observed in multiple cancers including breast cancer, pancreatic cancer and ovarian cancer. However, the role of LCN2 promoter methylation in the formation of microvessels is poorly understood. The aim of this study was to analyze the association of LCN 2 promoter methylation with microvessel formation and tumor cell proliferation in breast cancer patients. The LCN2 promoter methylation status was studied in 64 breast cancer tumors by methylation specific PCR (MSP). Evaluation of microvessel density (MVD) and Ki67 cell proliferation index was achieved by immunohistochemical staining using CD34 and MIB-1 antibodies, respectively. LCN2 promoter unmethylation status was observed in 43 (67.2%) of breast cancer patients whereas LCN2 methylation status was seen in 21 (32.8%). Further, LCN2 promoter unmethylation status was associated with aggressive tumor phenotype and elevated mean MVD in breast cancer patients.

• Journal of Korean Society on Water Environment
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• v.28 no.6
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• pp.804-812
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• 2012

This study contemplated domestic and other country's effluent limitation standards and suggested a methodology to establish technology-base limitation value. Current effluent limitation regulates industrial point sources discriminated by discharge flow rate and by regional distinction in Korea. Discharged $BOD_5$ load from large-scale plants(flow rate above $2,000\;m^3/day)$ exceeds 50% of overall industrial wastewater, which present rationale for discrimination based on plant size. However, regional distinction and pollutant- specific regulation might be insufficient to meet practical effectiveness of wastewater management policy, due to the nearly same limitation. Water quality data and treatment methods were investigated in hospital industry. And their distribution of effluent $BOD_5$ concentrations was statistically analyzed to suggest limitation value. Effluent $BOD_5$ concentrations showed lognormal distribution and $95^{th}$ percentile was corresponded to 87.9 mg/L, which could be suggested as tentative effluent limitation in hospital industry. The $95^{th}$ percentile of log-transformed distribution showed similar value of 86.5 mg/L. This study demonstrated reasonable methodology for establishing effluent limitation reflecting wastewater characteristic and treatment technology in separately categorized industry.

• Journal of Environmental Impact Assessment
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• v.11 no.1
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• pp.25-36
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• 2002

The purpose of this study is to assess the environmental carrying capacity of Chongju City for the environmental management and the urban growth management. The urban environmental carrying capacity assessment of the city by the index of ecological footprint(EF), shows that the ecosystem of the city has been overloaded and most of the deficiencies has come from outside of the city. The EF index, the area of land per capita required for production and consumption in the city, was 1.731 ha per capita in 1989 and 1.901 ha per capita in 1999. On the other side, the ecologically productive land is 0.0175 ha per capita. It means that every citizen owes 1.88 ha per capita to the ecosystem in 1999. The land consumption of the city has increased by 0.1705 ha per capita during the last 10 years. The capacity of infrastructure and the service supply estimated by the Onishi model does not exceed the demand of the city in 1999. But the rapidly increasing population and fast urban growth need the expansion of the capacity. The water supply capacity of the city appears to be sufficient in 1999, but the water supply demand will increase in the future. The capacity of sewage treatment facilities seems to be sufficient, but the higher level of sewage treatment facilities should be adopted for the improvement of water quality as the generation of sewage will increase and its characteristics will also make the wastewater treatment difficult. Due to the decrease of solid waste generated, the land fill capacity for solid waste disposal is not insufficient at present, but the capacity will be saturated in the near future. Therefore, the scientific management system of solid wastes should be introduced. The air quality of the city meets both the national air quality standard and WHO recommendation standard, but the strong regulation and control of automobile emission gas such as CO, $CO_2$, NOx and HC is required for clean air.