• 대한한의학방제학회지
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• 제14권1호
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• pp.105-119
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• 2006

Objectives & Methods : This present study was performed to investigate the effect of Hwadamtongrak-Tang extract (HTT) on the regulation of cerebral hemodynamics in terms of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP)] in normal and cerebral ischemic rats. Also the effects of HTT on changes in local blood flow, inhibition of LD H activity in neuronal cells, and levels of cytokine production in the serum were determined in the ischemic rat model. The major findings are summarized below. Results : 1. HTT significantly increased rCBF in a dose-dependent manner, but MABP was not changed by HTT treatment. These results suggest that HTT may increase rCBF by dilating cerebral arterial diameter. 2. HTT-induced increase in rCBF was blocked by pretreatment with cyclooxygenase inhibitor indomethacin (IDN, 1 mg/kg, i.p.) and MABP was significantly increased by ID N. 3. Pretreatment of methylene blue $(MTB,\;10\;{\mu}g/kg,\;i.p.)$, an inhibitor of guanylate cyclase, significantly decreased both rCBP and MABP in HTT-treated rats. 4. HTT treatment significantly increased rCBP to a stable level during the period of cerebral reperfusion. 5. HTT significantly inhibited LD H activity in neuronal cells, suggesting a neuroprotection by HTT. 6. Serum interleukin $(IL)-1{\beta}$ and tumor necrosis factor $(TNF)-{\alpha}$ levels were significantly decreased in the femoral artery 1 hr after middle cerebral arterial occlusion in HTT-treated rats. IL-10 levels in the serum were significantly increased by HTT treatment whereas transforming growth factor $(TGF)-{\beta}$ levels were similar between HTT-treated and control groups. 7. Serum interleukin $(IL)-1{\beta}$ and tumor necrosis factor $(TNF)-{\alpha}$ levels were significantly decreased in the femoral artery 1 hr after reperfusion in HTT-treated rats. Serum IL-10 levels were significantly decreased in HTT-treated rats compared with the control group, and no significant changes in $(TGF)-{\beta}$ in the serum were observed by HTT treatment. Conclusions: The present data suggest that HTT may have an anti-ischemic effect via the improvement of cerebral hemodynamics and thus protect the brain from ischemic damage.

• 한국유기농업학회:학술대회논문집
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• 한국유기농학회 2009년도 하반기 학술대회
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• pp.281-281
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• 2009

Although national and regional environmentally friend agriculture (EFA) and food development programmes such as the Life-Food Development Plan (LFDP) have been established in Korea, some policy measures in these programmes seem to be unsuitable for Korean organic farming development. Policy measures tend to support external input purchases of organic fertilizers rather than market development actions such as providing consumer information, research, education, training and statistical data collection. The development of an organic action plan (OAP) for Korea is therefore considered essential for the sustainable future of organic farming in Korea. The purposes of OAP are 1) to define and set the clear goals/targets for the organic sector development, 2) to integrate various organic stakeholders and public institutions in partnership, 3)to focus on specific issues with tailored measures and 4) to integrate and develop different policy measures (Stolze, 2005). Most EU member state countries have developed their own OAPs and each reflects its own priorities with regard to organic sector development. This study compares and contrasts the Welsh, England and EU OAP with the Korean Jeonnam Life-Food Development Plan (LFDP) in order to facilitate the development of the organic food and farming sector in Korea. Early action plan, for example, the first Welsh OAP(1999) focused support on developing the supply of organic products whereas later action plans (e.g. England OAPs in 2002 and 2004 and the second Welsh OAP in 2005) focussed more on developing consumer demands for organic products. The EU OAP (2004) also aims at market support related to consumer demand and then organic farming production for its environmental and other social benefits. OAPs not only provide specific issue-solving tools but also perform a role as providing a focus for organic sector development as a whole. The Korean LFDP provides issue-solving tools but plays no regulatory role such as policy development, harmonizing various policy measures and conflicting factors and providing evaluation tools for further development. A national-level OAP could also facilitate international trade of organic products. To achieve better harmonized and sustainable approaches for the Korean organic industry, National- as well as regional- regulatory policy systems are urgently required in the form of an Organic Action Plan.

• 한국작물학회지
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• 제27권4호
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• pp.385-397
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• 1982

The climatic impacts have been the environmental constraints with soil characteristics to achieve self sufficiency of food production in Korea. In this paper, the distribution and appearance of impacts and the changes in climatological status due to recent trend of early transplanting of rice are widely discussed to derive some countermeasures against the impacts, being focussed on cultural A long term analysis of the climatic impact appearances of the last 74 years showed that drought, strong wind, flood, cold spell and frost were the major impacts. Before 1970's, the drought damage was the greatest among the climatic impacts; however, the expansion and improvement of irrigation and drainage system markedly decreased the damage of drought and heavy rain. The appearance of cold damage became more frequent than before due to introduction of early transplanting for more thermophilic new varieties. Tongillines which were from Indica and Japonica crosses throw more attention to cold damage for high yields to secure high temperature in heading and ripening stages and lead weakness to cold and drought damage in early growth stage after transplanting. The plants became subject to heavy rain in ripening stage also. For the countermeasures against cold damage, the rational distribution of adequate varieties according to the regional climatic conditions and planting schedule should be imposed on the cultivation. A detoured water way to increase water temperature might be suggestable in the early growth stage. Heavy application of phosphate to boost rooting and tillering also would be a nutritional control method. In the heading and ripening stages, foliar application of phosphate and additional fertilization of silicate might be considerable way of nutritional control. Since the amount of solar radiation and air temperature in dry years were high, healthy plants for high yield could be obtained; therefere, the expansion of irrigation system and development of subsurface water should be performed as one of the national development projects. To minimize the damage of strong wind and rainfall, the rational distribution of varieties with different growing periods in the area where the damage occurred habitualy should be considered with installation of wind breaks. Not only vertical windbreaks but also a horizontal wind break using a net might be a possible way to decrease the white heads in rice field by dry wind. Finally, to establish the integrated countermeasures against the climatic impacts, the detailed interpretation on the regional climatic conditions should be conducted to understand distribution and frequency of the impacts. The expansion of observation net work for agricultural meteorology and development of analysis techniques for meteorological data must be conducted in future together with the development of the new cultural techniques.

• 한국지역지리학회지
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• 제4권1호
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• pp.99-120
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• 1998

1980년대부터 부산시에서 분산된 공업의 입지가 활발한 경상남도 김해군 장유면의 공업화 과정, 공업 입지요인, 지역적 연계를 구명하였다. 장유면의 공업입지는 주로 1980년대이후 중심도시인 부산시로부터 분산한 소규모 외향성 공업이 용지 확보, 원료공급처나 모기업과의 접촉, 기업주의 접촉경제면에서 유리한 장유면에 입지 함으로서 이루어졌다. 부산시에 인접한 관계로 입지변동에 따른 지역적 연계의 변화는 크지 않았다. 독과점 상태로 공급되는 원료를 거리와 관계없이 구입하여 제품의 특성 때문에 근거리, 특히 부산시에 입지한 모기업에 출하하는 하청업체로 존재하고 있다. 조직형태, 규모, 업종에 따라 입지요인과 지역적 연계의 차이를 나타내고 있지만 조직형태와 규모면에서 만 입지속성과의 관련성이 발견된다.

• Asian-Australasian Journal of Animal Sciences
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• 제21권5호
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• pp.715-722
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• 2008

There are marked variations in the activity of lipoprotein lipase (LPL) among adipose depots. The aim of this study was to compare the mechanisms of 24 h of fasting on LPL regulation between epididymal (EPI) adipocytes and mesenteric (MES) adipocytes in rats. 1-Day fasting consistently decreased activities of heparin-releasable LPL, total extractable LPL and cellular LPL markedly in both EPI and MES fat pads. LPL activity in MES fat pads was relatively lower than in the EPI fat pads. Consistent with data on LPL activity, the levels of expression of LPL mRNA in both nutritional states were lower in MES than EPI adipose tissue and isolated adipocytes. The decreased LPL activity after 1 day of fasting in MES adipocytes was explained mainly by a 50% decrease in the relative abundance of LPL mRNA level and a parallel 50% decrease in relative rate of LPL synthesis. In contrast, fasting of 1 day in EPI adipocytes decreased total LPL activity by 47% but did not affect LPL mRNA level or relative rate of LPL synthesis. A decrease in overall protein synthesis contributed to the decreased LPL activity after 1 day fasting both in EPI and MES adipocytes. In MES adipocytes the decrease in LPL activity, LPL mRNA and LPL synthesis were comparable, but in EPI adipocytes the changes in LPL activity were substantially larger than the changes in LPL mRNA level and LPL synthesis. Therefore, fasting decreased fat cell size, LPL activity, LPL mRNA level and relative rate of LPL synthesis in rats, and these effects were more marked in the MES adipocytes. These results clearly demonstrate the regional variations in the metabolic response of adipose tissue and LPL functions to fasting.

• 한국재난정보학회 논문집
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• 제16권2호
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• pp.364-373
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• 2020

연구목적: 각 지자체들은 다양한 문화공간을 보유하고 있다. 하지만 이용자들은 문화 관련 정보나 위치 등을 정확히 알지 못한다. 따라서 필요한 정보들을 지역주민들은 물론 외지인들에게 효과적으로 전달하기 위한 정보기술 적용 방법이 필요하다. 본 논문에서는 지역문화 공유를 위한 정보의 자발적인 생산과 이용자 스스로의 환경보호를 위한 방법을 연구하였다. 연구방법: 이를 위하여 QR코드, 빅데이터 분석, SNS에 기반을 둔 상호작용 홈페이지 등의 정보기술을 활용하였다. 연구결과: 그 결과로 이용자들에 의한 자생적인 커뮤니티 형성 방법과 이런 활동에 따른 개인정보 보호 방안을 도출하였다. 결론: 이 연구로 이용자들이 지역문화에 대한 이해를 높이고, 자율적인 환경 개선 참여를 유도하여 지역문화 발전에 기여할 수 있을 것이다.

• 한국항해항만학회지
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• 제43권6호
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• pp.469-474
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• 2019

세계의 주요 자원중 하나인 원유는 산업의 가장 기초적인 부분을 담당하고 있으며 원유를 통하여 많은 액체화물이 생산되고 있다. 석유화학단지들은 인근의 항만을 통해 원유를 수입후 정제를 통해 석유정제품, 화학생산공업품 등을 생산한다. 본 연구에서는 우리나라의 주요 석유화학단지와 인근에 위치한 액체화물 항만 간의 관계를 확인하고자 울산항, 대산항, 여수광양항을 선정하였다. 항만물동량 시계열 데이터를 이용한 분석을 실시하였으며 VAR 모형을 이용하였다. 이를 수행하기 위해 단위근 검정을 실시했으며 Granger 및 Toda-Yamamoto 인과 검정을 통하여 관계를 확인하였다.

• 농촌계획
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• 제12권1호
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• pp.23-35
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• 2006

The purpose of this study were to identify the different farming styles of red pepper growers, to describe their characteristics and to get some implications far planning the agricultural development strategy in the area. The researcher surveyed quantitative and qualitative data through interview with researcher developed questionnaires from selected 99 farmers in Eumsung county, Chungbuk province, Korea. The researcher found the low types of red pepper farming: 'red-pepper-centric middle farmers', 'diversified larger farmers', 'red-pepper-dependant small farmers', and 'small farmers for own use'. Based on the above findings, the researcher could derive some implications as follows. Firstly, the difference of market strategy and marketing efforts among the four farming styles should be regarded as important considerations when planning the agricultural development strategy in Emsung county. Secondly, the cooperatives' red pepper marketing strategies in Eumsung county were focused on the processed red pepper products sold at middle or low priced by big retailers in urban areas. Therefore, the cooperatives should change their view point of quality, if they want to initiate the planning process of 'the production and marketing high quality red pepper'. Thirdly, the major efforts of Eumsung county Agricultural Technology Center (ATC) made efforts on increasing the productivity of red pepper farming, however, the technologies recommended by the ATC for farmers required more cost and labour especially for 'red-pepper-dependant small farmers' and 'diversified large farmers'. The ATC should make efforts to find new technologies for helping 'red-pepper-dependant small farmers' to reduce the use of pesticides and 'diversified large farmers' to use the regional images effectively for marketing their hish quality red peppers.

• 한국임상약학회지
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• 제25권3호
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• pp.166-170
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• 2015

Background: Primary warm autoimmune hemolytic anemia (AIHA) is a relatively rare hematologic disorder resulting from autoantibody production against red blood cells. There has been very few studies about primary warm AIHA in South Korea because of its low incidence. We retrospectively analyzed the treatment outcome of primary warm AIHA. Method: We reviewed retrospectively the medical records of 9 primary warm AIHA patients from December 2002 to January 2015. We analyzed the causes and clinical characteristics of primary warm AIHA patients. We retrospectively analyzed the clinical data in electronic medical records for 9 Korean patients with AIHA patients who were diagnosed during the period from December 2002 to January 2015 at the Regional University Hospital in Korea. The study protocol was approved by the Institutional Review Board (IRB #2015-08-007, Chosun University Hospital IRB). Results: The mean age was 52 years (range 27~78), the mean hemoglobin level was 5.0 g/dL (range 2.5~6.4 g/dL). All patients received steroids at therapeutic dosages (corticosteroid 1 mg/Kg) as first line treatment. Eight of them showed complete response (5/8, 62.5%) and partial response (3/8, 37.5%), one patient required second-line treatment with rituximab. Two patients who responded first line treatment were relapsed at 86 weeks and 24 weeks after response, respectively. Only one patient of them was retreated with corticosteroid because of anemic symptoms. Conclusion: This study indicates that oral corticosteroid is an effective therapy for primary warm AIHA.

• 대한공간정보학회지
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• 제25권1호
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• pp.3-8
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• 2017

본 연구에서는 앙상블 중규모기후모델 weather research and forecasting(WRF)를 이용하여 2045년부터 2054년까지 21세기 중반의 기후변화에 대한 우리나라 미래 풍력자원 지도를 제작하였고 월별, 시간대별 자원변화를 검토하였다. 분석결과, 한반도상에서 강한 몬순 순환으로 인해 뚜렷한 월별 시공간 변동성이 해륙풍에 의한 시간대별 변동성보다 컸다. 풍력자원이 큰 강풍지역은 월마다 지역마다 다르게 나타났다. 즉 겨울철 북서계절풍(여름철 남서계절풍)이 주풍일 때 각각 강원산간과 해상 그리고 남서해안에서 자원이 많을 것으로 전망되었다. 최대풍과 최소풍은 1월, 9월에 각각 나타날 것으로 전망되었고, 시간대별로 내륙과 산간은 일중편차가 컸지만 연안지역은 편차가 작을 것으로 전망되었다. 이는 현재기후에 대한 기존분석결과와는 다소 차이가 있는 것으로, 이 연구에서 생산된 미래 풍력자원 지도는 향후 기후 변화 가능성이 큰 지역의 시공간적 풍황을 감안하여 풍력단지 입지 선정 및 풍력운영을 위한 장기계획 마련에 있어서 유용한 자료가 되리라 기대된다.