• Journal of mucopolysaccharidosis and rare diseases
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• v.4 no.1
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• pp.11-13
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• 2018

In Malaysia, diagnosis and treatment of patients with mucopolysaccharidoses (MPS) is mainly localized at Hospital Kuala Lumpur, which is the national referral center for rare diseases. To date there are 83 patients diagnosed with MPS in our center, with MPS II being the commonest. The Malaysian National Medicines Policy second edition has a specific section on the orphan drugs which includes recombinant human enzyme for enzyme replacement therapy (ERT) in MPS. So far, National Pharmaceutical Regulatory Agency Malaysia has approved recombinant human enzyme for MPS types I (Loranidase), II (idursulfase), IVA (elosulfase alfa), and VI (Galsufase). Access to Idursulfase beta (another recombinant human enzyme for MPS II) and vestronidase alfa-vjbk (MPS VII) required special authorization on named patient basic. Currently there are 25 patients receiving ERT, 70% of the funding are from Ministry of Health (MOH), the remaining 30% are from various charitable funds and humanitarian programs. Thirteen newly diagnosed patients have to queue for an additional fund. Four patients have been treated with Hematopoietic stem cell transplant. MOH has also published guidelines regarding the patient selection criteria for ERT and treatment monitoring schedule.

• Journal of the Korean Society for information Management
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• v.18 no.4
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• pp.217-233
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• 2001

KORMARC used in library bibliographic information, had been pointed several weaknesses such as inflexibility lack of link information and compatibility. In addition, a sudden increase in digital information associated with development of internet is demanding an integration of web resources metadata as the resource of library information. This study mentioned XML/KORAMARC system or adaption of XML standard format turned out to be the most efficient way to use KORMARC formats and to expand the range of those information service such as bibliographic information, factual information, referral information and full-text.

• The Korean Journal of Pain
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• v.24 no.2
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• pp.112-114
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• 2011

Due to its complex pathophysiology and wide spectrum of clinical manifestations, the diagnosis of CRPS is often missed in the early stage by primary care physicians. After being treated by a primary care physician for 5 months for chronic cellulitis, a 16-year-old girl was referred to our hospital with features of type-1 CRPS of the right upper extremity. Inability to diagnose early caused prolonged suffering to the girl with all the consequence of CRPS. The patient responded well with marked functional recovery from multimodal therapy. Ability to distinguish CRPS from other pain conditions, referral for specialty care at the appropriate time and full awareness of this condition and its clinical features among various healthcare professionals are essential in reducing patient suffering and stopping its progression towards difficult-to-treat situations.

• Imaging Science in Dentistry
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• v.45 no.4
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• pp.263-265
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• 2015

Cone-beam computed tomography (CBCT) is routinely recommended for dental diagnosis and treatment planning. CBCT exposes patients to less radiation than does conventional CT. Still, lack of proper education among dentists and specialists is resulting in improper referral for CBCT. In addition, aiming to generate high-quality images, operators may increase the radiation dose, which can expose the patient to unnecessary risk. This letter advocates appropriate radiation dosing during CBCT to the benefit of both patients and dentists, and supports moving from the concept of "as low as reasonably achievable" (ALARA) to "as low as diagnostically acceptable" (ALADA).

• Journal of Periodontal and Implant Science
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• v.44 no.6
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• pp.293-299
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• 2014

Purpose: Systemic disease can manifest oral signs at an early phase, which may be crucial for the diagnosis and timing of treatment. This report describes two patients who presented with gingival enlargement as an early sign of acute leukemia. Methods: Two patients presented with oral symptoms including severe gingival enlargement. The progress of their symptoms was associated with underlying systemic disease. Results: The patients were transferred to the Department of Hematology and diagnosed with acute myelomonocytic leukemia. They received appropriate treatment and survived. Conclusions: Gingival enlargement can be caused by underlying systemic diseases. Accurate diagnosis and timely referral are important for preventing a fatal situation. It must be emphasized that some oral signs and symptoms may be closely correlated with systemic diseases.

• International Commerce and Information Review
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• v.8 no.1
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• pp.33-50
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• 2006

This research develops, and empirically test a model for explaining/predicting the Determinants and Satisfaction of Portal Cite in Internet Initiation Page. Also this paper describes a theoretical model for investigating the service quality satisfaction in the Internet Initiation Page. This research is the first to empirical test the causal relationships in determinants of Portal Cite. The model of the satisfaction for Portal Cite are tested here using data from 224 samples. Based on the research model, a comprehensive set of hypotheses is formulated and a methodology for testing them is outlined. some of the hypotheses are tested empirically to demonstrate the applicability of the theoretical model. In examining the relationships of the determinants factors, satisfaction show in significantly by Convenience, Information Provided, Entertainments, Interaction but that show in not significantly by the Trustworthiness, In addition, Portal Cite in Internet Initiation Page shows indirect effect between customer satisfaction and referral.

• Research in Community and Public Health Nursing
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• v.12 no.1
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• pp.22-31
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• 2001

Purpose of this study is to compare the cost effectiveness of home care services for the cerebrovascular accident patients by the type of institution. The method is the secondary analysis using the patients' charts. 107 subjects and 1.417 visits were sampled from each type of home care institution such as one hospital based home care center. one KNA home care center, one urban health center, one rural health center and one health care post. Result: There were differences in the functional status of patients and the service contents and frequencies provided by the type of home care institution, The cost per visit for one unit of ADL by the hospital based home care was higher than by the community-based home care. Conclusion: It was suggested that the referral system among the home care institutions would be developed to improve the cost-effectiveness.

• Journal of Information Management
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• v.25 no.2
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• pp.61-94
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• 1994

The development of libraries services has been influenced by the nature and the changes of social environment where the library's functions are ultimately fulfilled. Community information services of libraries are designed to cope with the changes more efficiently in information society. In this paper, the concept and background of community information services are introduced and expected benefits of offering them are discussed. In addition, based on the results which examination 19 public libraries in seoul, some recommendations for effective community information services are suggested.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10b
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• pp.778-780
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• 2003

최근 XML 문서가 여러 분야의 시스템에서 정보 교환과 메시지 전송을 위한 표준으로 자리 잡으면서 의료계에서도 응용 프로그램 간의 메시지 전송 혹은 병원 간 환자의료정보를 교환하기 위한 XML기반의 정보 교환 프로토콜 표준화가 계속 진행 중에 있다. 하지만 이러한 환자의료정보가 인터넷을 통해 병원간에 이동할 때, 여러 보안상의 위협에 노출될 수 있다. 이에 본 논문에서는 기존의 보안 메커니즘의 한계점을 보완하면서 XML 기반의 정보를 보호하기 위한 가장 효율적인 메커니즘으로 인정받은 XML 보안기술을 적용한 환자의뢰시스템을 시스템을 구현하고 보안 메커니즘 적용 시 부득이하게 발생할 수 있는 성능 저하 정도를 알아보기 위해 성능 평가 테스트를 실시한다.

• Korean Journal of Veterinary Research
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• v.36 no.4
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• pp.895-902
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• 1996

산란계에 불활화 개 파보바이러스 백신을 근육내로 1주 간격으로 4회 접종하여 면역화시키고 최종 접종 2주후에 채란하여 $4^{\circ}C$에 보관하며 사용하였다. 난황항체는 5% HPMCP를 이용하여 분리하였고 0.5% HPMCP 용액은 lipid 침전에 매우 효과적이었으며 희석배수 10배에서 투명한 상층액을 나타내었다. 1차분리한 상층액의 단백질 농도는 2.5mg/ml이었고 최종 단백질 용액의 경우는 26.53mg/ml이었다. SDS-PAGE 전기영동상에서 분자량 60~70 KD 및 30~40 KD의 2 band가 나타났으며 non-reducing 전기영동에서는 닭 혈청 IgG와 같은 120~160 KD의 분자량을 보인 band가 각각의 분리용액에서 나타났다. 난황 항체의 개 파보바이러스에 대한 혈구응집억제반응 항체역가는 혈청의 역가에 비해 1주의 차이를 주며 증가했으며 난황 항체는 1:640에서 1:2560, 혈청은 1:640에서 1:5120을 나타내었다.