• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8419-8423
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• 2016

Purpose: Anti-cancer activity evaluation of aqueous extract of CRUEL (herbomineral formulation) capsules on renal cell carcinoma cell lines, and exploration of mechanisms of cell death. Materials and Methods: To detect the cytotoxic dose concentration in renal cell carcinoma (RCC) cells, MTT assays were performed and morphological changes after treatment were observed by inverted microscopy. Drug effects against RCC cell lines were assessed with reference to cell cycle distribution (flow cytometry), anti-metastatic potential (wound healing assay) and autophagy(RT-PCR). Results: CRUEL showed anti-proliferative effects against RCC tumor cell lines with an IC50 value of ${\approx}4mg/mL$ in vitro., while inducing cell cycle arrest at S-phase of cell cycle and inhibiting wound healing. LC3 was found to be up-regulated after drug treatment in RT-PCR resulting in an autophagy mode of cell death. Conclusions: This study provides the experimental validation for antitumor activity of CRUEL.

• 한국식품영양과학회지
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• 제23권2호
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• pp.358-370
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• 1994

Plant cell walls consist of a variety of chemical constituents such as cellulose, humicelluloses, pertins, lignin, glycoproteins, etc. These components are strongly linked through hydrogen , covalent, ionic and hydrophobic bondings, which thus confers the self-protection capability on plants. Some processing by-products (hulls, brans, pomaces) of cereal, fruits and vegetables are very limited in further utilization due to their compact structural rigidity. In view of the fact that the plant cell walls are essentially composed of dietary fiber components , solubilization of the strong intermolecular linkage s can contribute to increasing the soluble dietary fiber content and thus diversifying the functional and physiological role of plant cell walls as dietary fiber sources. This article reviews the chemical constituents of cereals, fruits & vegetables and brown seaweeds with reference to their intermoleuclar linkages. An particular emphasis will be placed on the solubilizing phenomena of rigid plant cell walls by extrusion and the resulting change of functional properties. It is suggested that underutilized food resources, typically exemplified by various food processing by-products and surplus seaweeds, can be successfully modified toward improved functional performance by extrusion.

• 한국정보통신학회논문지
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• 제16권12호
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• pp.2725-2730
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• 2012

본 논문에서는 H.264/AVC 인코더의 성능 향상을 위해 다중 참조 프레임 기법과 묵시적 가중 예측 기법을 이용하고 낮은 외부 메모리 접근율을 위해 이전 참조 프레임 데이터를 재사용하는 인터 예측기 하드웨어 구조를 제안한다. 참조 소프트웨어JM16.0과 비교하여 참조 프레임 접근율이 약 24%만큼 감소하고 참조 영역 메모리가 약 46%만큼 감소하였다. 통합 구조는 Verilog HDL로 설계되고 Magnachip 0.18um공정으로 합성한 결과 게이트 수는 약 2,061k 이고 91Mhz로 동작한다.

• Journal of information and communication convergence engineering
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• 제14권4호
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• pp.207-214
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• 2016

In this paper, we propose a radial reference map-based location fingerprinting technique with constant spacing from an access point (AP) to all reference points by considering the minimum dynamic range of the received signal strength indicator (RSSI) obtained through an experiment conducted in an indoor environment. Because the minimum dynamic range, 12 dBm, of the RSSI appeared every 20 cm during the training stage, a cell spacing of 80 cm was applied. Furthermore, by considering the minimum dynamic range of an RSSI in the location estimation stage, when an RSSI exceeding the cumulative average by ${\pm}6dBm$ was received, a previously estimated location was provided. We also compared the location estimation accuracy of the proposed method with that of a conventional fingerprinting technique that uses a grid reference map, and found that the average location estimation accuracy of the conventional method was 21.8%, whereas that of the proposed technique was 90.9%.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 하계학술대회 논문집 Vol.9
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• pp.148-149
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• 2008

As infrared light is radiated, the CMOS Readout IC (ROIC) for the microbolometer type infrared sensor detects voltage or current when the resistance value in the bolometer sensor varies. One of the serious problems in designing the ROIC is that resistances in the bolometer and reference resistor have process variation. This means that each pixel does not have the same resistance, causing serious fixed pattern noise problems in sensor operations. In this paper, Reference resistor compensation technique was proposed. This technique is to compensate the reference resistance considering the process variation, and it has the same reference resistance value as a bolometer cell resistance by using a comparator and a cross coupled latch.

• 정보처리학회논문지B
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• 제11B권2호
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• pp.141-148
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• 2004

영상 매칭 방법을 이용하여 항공 사진 및 위성 영상으로부터 획득한 지상 위치 및 고도 정보인 수치표고모델(DEM)은 여러 환경의 영향으로 인하여 오차를 포함하고 있다. 본 연구에서는, 전문가가 이러한 오차를 수정 편집할 수 있도록 하기 위하여 기준 수치표고모델과 대상 수치 표고모델간의 유사도 값을 사용하여 수치표고모델을 평가하는 방법을 제시하고자 한다. 수치표고모델의 전 지역에 대해 수평 및 수직 오차를 구하기 위해서는 기준 수치표고모델의 격자와 대상 수치표고 모델 격자간의 유사도 값을 사용하여 각 기준 격자에 대한 정합 대상 격자를 구한다. 각 기준 격자에 대한 정합 대상 격자가 구해지면, 수평 및 수직 오차를 계산하여 전문가가 수정 편집할 영역을 판단할 수 있도록 한다. 즉, 유사도 값이 낮고, 고도의 차가 높은 경우. 그 격자는 후보 변화 또는 오류 격자로 판단된다. 이러한 후보 격자들이 영역을 이룰 경우. 수정 편집 대상인 변화 또는 오류 지역으로 판단한다. 이러한 방법을 사용함으로써, 모든 점에 대한 평가가 가능할 뿐 아니라, 수직 오차 외에도 수평 오차를 구할 수 있으므로, 보다 효과적으로 변화 또는 오류 지역을 찾을 수 있었다.

• 한국임상수의학회지
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• 제23권2호
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• pp.111-113
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• 2006

수컷 엘크 사슴 85두에서 채혈하여 한국에서 사육되는 엘크사슴의 혈액화학치에 대한 정상범위를 설정하였다. 적혈구수에 대한 참고범위는 6.01-9.93 (${\times}10^6/mm^3$)이었으며, 헤모글로빈농도에 대하여는 10.90-19.70 (g/dl), 적혈구용적은 43.10-76.40 (%), 총백혈구수에 대하여는 2.60-7.68 (${\times}10^6/mm^3$)으로 산정되었다. 위의 네가지 혈액화학치에 관하여 한국 및 외국에서 기발표된 자료와 비교하면서 본 연구에서 설정된 참고범위의 값들의 타당성을 검증하였다.

• 한국임상수의학회지
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• 제35권3호
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• pp.77-82
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• 2018

The aim of this study was to measure whole blood viscosity (WBV) and then to establish its reference values and identify correlation between WBV and hematology or serum chemistry in beagle. The experiment was made up of 82 healthy beagle dogs. Jugular vein blood samples (10 ml) were collected. WBV (cP) measured within 4 hours after collection by U-shaped scanning capillary-tube viscometer ($BVD-PRO1^{(R)}$) which is capable of measuring yield stress and viscosity of whole blood continuously over a wide range of shear rates from $1s^{-1}$ to $1000s^{-1}$ is new type of capillary tube viscometer and calculates viscosity using Casson fluid model. Measured values of WBV, Complete blood cell count, serum chemistry were analyzed by RM-ANOVA test. Mean diastolic and systolic WBV (cP) were $29.032{\pm}6.137$ and $4.528{\pm}0.865$. Bodyweight (BW), Red blood cell count (RBC), Hemoglobin (HGB), Hematocrit (HCT), Alkaline phosphatase (ALP), Cholestetol (CHOL), Total protein (TP), Globulin, Chloride (Cl), Fibrinogen, were statistically correlated with WBV over whole range of shear rates (p < 0.05). This study newly evaluated reference values of WBV by U-shaped viscometer in beagle. Correlation between WBV and BW, RBC, HGB, HCT, ALP, CHOL, TP, Globulin, Cl, Fibrinogen was presented.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2008년도 하계학술대회 논문집
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• pp.103-105
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• 2008

In grid-interconnection system, a fast, robust and precise phase angle detector is most important to grid synchronization and the active power control. The phase angle can be easily estimated by synchronous dq PLL system. On the other hand under unbalanced voltage condition, synchronous dq PLL system has problem that harmonics occur to phase angle or magnitude of grid voltage because of the effect of the negative sequence components. So, To eliminate the negative sequence components, the PLL method using APF (All Pass Filter) in a stationery reference frame to extract positive sequence components under unbalanced voltage condition is researched. In this paper, we propose a new PLL method with decoupling network using APF in a synchronous reference frame to extract the positive sequence components of the grid voltage under unbalanced grid. The cut-off frequency of APF in a synchronous reference frame can be set to twice of the fundamental frequency comparing with that of APF in a stationery reference frame which is the fundamental frequency. The proposed PLL strategy can detect the phase angle quickly and accurately under unbalanced gird voltages. Simulation and experimental results are presented to verify the proposed strategy under different kind of voltage dips.

• 한국동물위생학회지
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• 제40권2호
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• pp.155-159
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• 2017

Korean goral (Neamorhedus caudatus) is registered as a natural monument number 217 by South Korea Cultural Heritage Administration. It is also recognized as the endangered species I by Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). In this study, blood samples of Korean goral were collected to make reference intervals. Blood sampling was conducted on 19 numbers of Korean gorals (ten females, nine males), which were reared in Korean Goral Restoration Center. For total samples, the reference intervals of hematological parameters were: white blood cell $7.69{\sim}10.87K/{\mu}{\Lambda}$; hematocrit 36.73~46.18%; red blood cell $10.72{\sim}12.86K/{\mu}{\Lambda}$; hemoglobin 12.79~15.14 g/dL; mean corpuscular volume 33.15~36.75 fL; mean corpuscular hemoglobin 11.53~12.23 pg; mean corpuscular hemoglobin concentration 32.64-35.91 g/dL and red blood cell distribution width 39.2~43.46%. For total samples of each parameters, the following results were obtained for serum biochemistry: glucose 111.81~153.77 mg/dL; blood urea nitrogen 22.35~28.91 mg/dL; creatine 1.22~1.84 mg/dL; phosphate 4.57~6 mg/dL; calcium 8.7~9.1 mg/dL; total protein 6.53~6.92 g/dL; albumin 3.1~3.48 g/dL; globulin 3.26~3.62 g/dL; alanine aminotransferase 56.7~158.56 U/L; aspartate aminotransferase 230.35~473.06 U/L; alkaline phosphatase 178.06~332.47 U/L; gamma-glutamyl transpeptidase 131.6-~181.24 U/L; total bilirubin 1.47~2.12 mg/dL; cholesterol 46.48~71.52 mg/dL; amylase 16.3~26.03 U/L; sodium 150.43~153.88 mmol/L; potassium 3.98~4.6 mmol/L and chlorine 109.48~113.26 mmol/L. The ranges of values were similar campared to previous studies except in the case of RDW value, which showed higher range than the RDW value of a previous study. The reference intervals from this study will be useful data for treatment and management of gorals.