• Title/Summary/Keyword: Reference Population

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Genetic Linkage Mapping of RAPD Markers Segregating in Korean Ogol Chicken - White Leghorn Backcross Population

  • Hwang, K.C.;Song, K.D.;Kim, T.H.;Jeong, D.K.;Sohn, S.H.;Lillehoj, H.S.;Han, J.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.3
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    • pp.302-306
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    • 2001
  • This study was carried out to construct mapping population and to evaluate the methods involved, including polymorphic DNA marker system and appropriate statistical analysis. As an initial step to establish chicken genome mapping project, White Leghorn (WL) and Korean Ogol chicken (KOC) were used for generating backcross population. From 8 initial parents, total 280 backcross progenies were obtained and 40 were used for genotyping and linkage analysis. For development of novel polymorphic markers for KOC, Random Amplified Polymorphic DNA (RAPD) markers specific for this chicken line were generated. Also included in this study were six microsatellite markers from East Lansing map as reference loci. For segregation analysis, 15 RAPD markers and 6 microsatellites were used to genotype the backcross population. Among the RAPD markers that we developed, 2 pairs of markers were identified to be linked and another 4 RAPD markers showed linkage with microsatellites of known map. In summary, this study showed that our backcross population generated from the mating of KOC to WL serves as a valuable genetic resource for genotyping. Furthermore, RAPD markers are proved to be valuable in linkage mapping analysis.

Cone-beam computed tomography for the assessment of root-crown ratios of the maxillary and mandibular incisors in a Korean population

  • Choi, Sung-Hwan;Kim, Jung-Suk;Kim, Cheol-Soon;Yu, Hyung-Seog;Hwang, Chung-Ju
    • The korean journal of orthodontics
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    • v.47 no.1
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    • pp.39-49
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    • 2017
  • Objective: This retrospective, cross-sectional study aimed to establish reference data for normal crown and root lengths and the root-crown ratios (R/C ratios) for the mature maxillary and mandibular incisors in a Korean population by using cone-beam computed tomography (CBCT). Methods: We included 672 Korean patients (141 men and 531 women; mean age, $27.2{\pm}7.7years$) who underwent CBCT examinations during various dental treatments. Crown and root lengths and the R/C ratios of the maxillary and mandibular incisors were measured using CBCT data, which were analyzed to detect significant differences between demographic factors as well as sagittal and vertical skeletal or occlusal relationships. Results: Teeth of the same type in each half-arch were symmetrical. The mean R/C ratios varied from 1.1 to 1.2 for the maxillary incisors and from 1.3 to 1.4 for the mandibular incisors. Crown and root lengths were greater in men than in women, regardless of tooth type. Root lengths and R/C ratios for the mandibular incisors were significantly greater in patients with skeletal Class II malocclusion or an excessive overjet than in the other patients. The R/C ratios for the mandibular incisors were lower in patients with an open bite than in those with a normal or deep bite. Moreover, the R/C ratios for the mandibular incisors increased with age. Conclusions: The data obtained in our study can serve as reference values for crown and root lengths and the R/C ratios for the maxillary and mandibular incisors in the Korean population.

Evaluation of Pregnancy and Thyroid Function (임신과 갑상선 기능의 평가)

  • Park, Chang-Eun
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.1
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    • pp.1-10
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    • 2018
  • During early pregnancy, before the development of a functioning thyroid gland, thyroid stimulating hormone (TSH) is a very sensitive marker of thyroid dysfunction during pregnancy. Normal values have been modified during gestation with a downward shift. The fetus is influenced by the TSH supplied by the mother. TSH and free thyroxine (FT4) concentrations vary during pregnancy and conventional units can vary between laboratories. A downward shift of the TSH reference range occurs during pregnancy, with a decrease in both the lower and upper limits of maternal TSH, relative to the typical non-pregnant TSH reference range. Each laboratory produces its own reference TSH and FT4 concentrations because there are many different assays that yield different results in pregnancy. Therefore, automated immunoassays used for serum FT4 analysis are still used widely, but the important considerations discussed above must be noted. The use of population-based, trimester-specific reference ranges remains the best way to handle this issue The slight downward shift in the upper reference range of TSH occurring in the latter first trimester (7~12 weeks) of pregnancy, typically not observed prior to 7 weeks. Their use indicates high or low levels in a quantitative manner independent of the reference ranges. These data highlight the importance of calculating population-based pregnancy-specific thyroid parameter reference intervals. A precision medicine initiative in this area will require the collection and analysis of a large number of genetic, biological, psychosocial, and environmental variables in large cohorts of individuals. Large prospective randomized controlled trials will be needed to resolve these controversies.

Computer Literacy Skills as a Determinant of Electronic Reference Sources Utilization among Selected Secondary School Students in Ado-Odo Ota Local Government, Ogun State, Nigeria

  • Elizabeth Bukunola Lateef;Opene Sunday Ozonuwe;Adesanmi Mathew Farukuoye
    • International Journal of Knowledge Content Development & Technology
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    • v.14 no.2
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    • pp.81-97
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    • 2024
  • The study investigated computer literacy skills as a determinant of electronic reference sources utilization among selected secondary school students in Ado-Odo Ota Local Government, Ogun State, Nigeria. Four specific objectives with conforming research questions guided the study. Descriptive survey research design was adopted for the study. The population of the study comprises of SSS3 students of the three selected Community Secondary Schools in Ado Odo Ota. A sample size of 150 was used for the study. The instrument for data collection was a self-developed structured questionnaire. Data collected was analyzed using frequency and percentages. Findings of the study revealed that majority of secondary school students were not aware of the availability of electronic reference sources. It also revealed that the level of their computer literacy skills was below average. Majority of them have never used computer before and the few of them that have used computer before used it in their homes, their friend's homes or in the cyber café. It was found that lack of formal training on the use of electronic reference sources, lack of access to computer, lack of awareness of availability of electronic reference sources, lack of funds for internet subscriptions, over dependency on printed reference sources and lack of motivation to use electronic reference sources were the major hindrances to the use of electronic reference sources among secondary school students. It was recommended that the school librarians and teachers should play a role in creating awareness among secondary school students about the availability of online/ electronic reference sources among others.

Reference value of serum amyloid P : a systematic review (혈청 아밀로이드 P (SAP)의 정상 참고치 탐색을 위한 문헌 고찰)

  • Park, Sunju;Jung, Jeeyoun;Jang, Soobin
    • Journal of Society of Preventive Korean Medicine
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    • v.23 no.2
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    • pp.91-99
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    • 2019
  • Objectives : The aim of this study was to examine the reference value of biomarker serum amyloid p (SAP) to diagnose blood stasis objectively. Methods : Pubmed-Medline, Cochrane library, EMBASE were searched using the key words 'SAP' and 'serum amyloid p' in June 2018. Original articles of human adults that published in English, studies that recruited from the clinical research settings or well defined population based cohorts were only included. Results : A total of 12 studies were selected to extract the reference value of SAP. It was between 8.5 ng/mL (0.0085 mg/L) to 57.5 mg/L. Although the disease varied, most of them showed elevated SAP levels in the disease group (1.1-1.5 times). Conclusions : This study is meaningful in that it summarizes the results of previous researches of SAP, which has the potential to be diagnostic index of blood stasis.

Calibrations of Ultraviolet Excess as Metallicity Indicator of F,G,K Stars

  • Ann, Hong-Bae
    • Publications of The Korean Astronomical Society
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    • v.1 no.1
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    • pp.39-54
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    • 1984
  • For F,G,K stars, their photometric data and metallicity, [Fe/H] are collected and their correlations between $\delta$(U-B) and [Fe/H] for each spectral group are examined, using a reference sequence which is defined by the stars in Woolley's catalogue and other reference sequences. Detailed examination shows that the reference sequence by Woolley's catalogue appears to be properly defined for the calculation of $\delta$(U-B) of population I stars in the solar neighborhood. It is suggested that accuracies of metallicities derived from $\delta$(U-B) can be improved if we derive the correlations between [Fe/H] and $\delta$(U-B) from the stars in each spectral group.

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A Cost Effective Reference Data Sampling Algorithm Using Fractal Analysis

  • Lee, Byoung-Kil;Eo, Yang-Dam;Jeong, Jae-Joon;Kim, Yong-Il
    • ETRI Journal
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    • v.23 no.3
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    • pp.129-137
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    • 2001
  • A random sampling or systematic sampling method is commonly used to assess the accuracy of classification results. In remote sensing, with these sampling methods, much time and tedious work are required to acquire sufficient ground truth data. So, a more effective sampling method that can represent the characteristics of the population is required. In this study, fractal analysis is adopted as an index for reference sampling. The fractal dimensions of the whole study area and the sub-regions are calculated to select sub-regions that have the most similar dimensionality to that of the whole area. Then the whole area's classification accuracy is compared with those of sub-regions, and it is verified that the accuracies of selected sub-regions are similar to that of whole area. A new kind of reference sampling method using the above procedure is proposed. The results show that it is possible to reduce sampling area and sample size, while keeping the same level of accuracy as the existing methods.

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Archival Reference Service and Freedom of Information in Korea (기록정보 서비스와 정보공개 - 이용자 중심의 서비스 논쟁을 중심으로 -)

  • Youn, Eunha
    • Journal of Korean Society of Archives and Records Management
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    • v.12 no.2
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    • pp.163-179
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    • 2012
  • The author discusses the nature and scope of archival reference service through the debate to user studies in the 1980s and the 1990s. Until the 1990s, archivists paid little attention to studying their user population. A new approach to archival user service led to the development of various public services of archives and resulted in active interaction with the public. Based on the discussion, the article examines the implication of archival reference service in Korean society.

Silver ICT Trends and Policy Implications (실버ICT 동향과 정책적 시사점)

  • Han, Hyun-Soo
    • Journal of Information Technology Applications and Management
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    • v.21 no.4_spc
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    • pp.501-516
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    • 2014
  • Rapidly shifting to aging population is a global trend, and one of the challenging issue for the government, business and welfare perspective. In this paper, we focus on application potentials of information and communication technologies, to capture the insights for effectively coping with population aging issue. As the research for silver ICT field is rather limited, we adopt case study research method to extract policy implications and related foundation research agenda. As such, we first investigated comprehensive up-to-date trends, cases for innovative ICT applications, and policy initiatives mainly from the works of OECD nations. With reference to the review findings, we propose policy implications and guidelines for ICT innovations which contributes better quality of life and continuing job opportunities for silver population. The results provides insights for government policy initiative and further research in silver ICT area.

A Study on Potential Risk of Landslide in Pusan (부산지역의 산사태 위험 연구)

  • Lee, Su-Gon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.2 no.2
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    • pp.9-23
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    • 1999
  • Pusan's reputation as the nation's most crowded city in terms of population density is attributable to its huge mountains which allow only small portion of residential area to its large population. Rapid increase of urban population on limited amount of land had naturally led its developments efforts to mountainous area giving rise to the concern of potential landslide. This study on urban Pusan and "Landslide Hazard Map" thereof is prepared in an attempt to avoid disasters created by landslide and also as a reference for city planners. The Map shows that the area covering 38% to 43% of urban Pusan has the potential for landslide. The study also shows that various civil works involving massive land excavation had been more direct cause of landslides in Pusan than such traditional factors as locations, ground slopes, rock types and topography of the area concerned.

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