• Journal of the Society of Naval Architects of Korea
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• v.58 no.6
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• pp.348-357
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• 2021

In this paper, the generalized hydrodynamic force and response of a flexible body are calculated at different reference coordinate systems. We generalize the equation of motion for a flexible body by using the conservation of momentum (Mei et al., 2005). To obtain the equations in the generalized mode, two different reference coordinates are adopted. The first is the body-fixed coordinate system by a rigid body motion. The other is the inertial coordinate system which has been adopted for the analysis. Using the perturbation scheme in the weakly-nonlinear assumption, the equations of motion are expanded up to second-order quantities and several second-order forces are obtained. Numerical tests are conducted for the flexible barge model in head waves and the vertical bending is only considered in the hydroelastic responses. The results show that the linear response does not have the difference between the two formulations. On the other hand, second-order quantities have different values for which the rigid body motion is relatively large. However, the total summation of second-order quantities has not shown a large difference at each reference coordinate system.

• Journal of Platform Technology
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• v.11 no.5
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• pp.59-71
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• 2023

This paper proposes a method of estimating the illumination chromaticity of a scene in which an image is taken. Storring and Bianco proposed a method of estimating illuminant chromaticity using skin color. Storring et al. used skin color distribution characteristics and black body locus, but there is a problem that the link between the locus and CIE-xy data is reduced. Bianco et al. estimated the illuminant chromaticity by comparing the skin color distribution in standard lighting with the skin color distribution in the input image. This method is difficult to measure and secure as much skin color as possible in various illumination. The proposed method can estimate the illuminant chromaticity for any input image by analyzing the relationship between the skin color information and the illuminant chromaticity. The estimation method is divided into an analysis stage and a test stage, and the data set was classified into an analysis group and a test group and used. Skin chromaticity is calculated by obtaining skin color areas from all input images of the analysis group, respectively. A mapping is obtained by analyzing the correlation between the average set of skin chromaticity and the reference illuminant chromaticity set. The calculated mapping is applied to all input images of the analysis group to estimate the illuminant chromaticity, calculate the error with the reference illuminant chromaticity, and repeat the above process until there is no change in the error to obtain a stable mapping. The obtained mapping is applied to the test group images similar to the analysis stage to estimate the illuminant chromaticity. Since there is no independent data set containing skin area and illuminant reference information, the experimental data set was made using some of the images of the Intel TAU data set. Compared to Finlayson, a similar theory-based existing method, it showed performance improvement of more than 40%, Zhang 11%, and Kim 16%.

• The Journal of the Acoustical Society of Korea
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• v.27 no.5
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• pp.221-228
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• 2008

To estimate array shape with reference sources in SONAR systems, nearfield signal modeling is required for the reference sources near a towed array. Array shape estimation method based on the nearfield signal modeling generally exploits the spatial covariance matrix of the received reference sources. Among those method, nearfield eigenvector method uses the eigenvector corresponding to the maximum eigenvalue as a steering vector of the reference source. In this paper, we propose a simplified subspace fitting method based on the nearfield signal modeling with spherical wave modeling. Furthermore, we analyze performance of the array shape estimation methods based on the nearfield signal modeling for various environments. The results of the numerical experiments indicate that the simplified subspace fitting method and the nearfield eigenvector method with single reference source shows almost similar performance. Furthermore, the simplified subspace fitting method with 2 reference sources consistently estimates the shape of the array regardless of the incident angle of the reference sources, whereas the nearfield eigenvector method cannot apply for the case of 2 reference sources.

• Journal of Advanced Navigation Technology
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• v.21 no.1
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• pp.12-20
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• 2017

A maritime DGPS in Korea offers pseudo-range correction information and monitors integrity of correction data by using multiple GNSS receivers. The maritime DGPS reference station and integrity monitor service sets alarm threshold value about integrity monitoring parameters for preventing service interruption status. However there is no way to avoid system interruption according to malfunction of backup systems and outside factors. Therefore, in this paper, warning threshold values were proposed for maritime DGPS operator can be counteract in advance. And Markov analysis method was carried out for selection of these warning threshold values.

• Korean Journal of Health Education and Promotion
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• v.31 no.4
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• pp.1-10
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• 2014

Objectives: The effectiveness of Blood ${\beta}$-ketone testing by using self-monitoring strip on diabetic patients. Methods: Clinical effectiveness of blood ${\beta}$-ketone testing was assessed through correlation with reference test that measured blood ${\beta}$-ketone value through gas chromatography or enzyme method, diagnostic accuracy, time taken for the test and time taken for confirmative diagnosis of diabetic ketosis by selecting literatures on researches that conducted this test on ketosis(suspected) patients or diabetic ketosis(suspected) patients. Each of the stages from literature search to application of selection standards and extraction of data were carried out independently by the Subcommittee along with 2 researchers. Results: 7 reports were selected. ${\beta}$-ketone testing displayed high level of correlation in the range of r=0.92~0.99 with test using enzyme method as the reference standard. Regarding the diagnostic accuracy, sensitivity of 0.82, specificity of 0.74. The time taken for the test was 30seconds for the index test, which is shorter than reference standard test. Conclusion: Blood ${\beta}$-ketone testing was assessed to be a safe and effective test to monitor ketosis and assess the level of risk of ketosis by measuring the blood ${\beta}$-ketone on ketosis patients and diabetic ketosis patients since it has high level of correlation with reference test and short period of testing.

• Korean Journal of Clinical Pharmacy
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• v.13 no.1
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• pp.13-17
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• 2003

This study was carried out to compare the bioavailability of $Ceclex^{(R)}$ SR TAB (test drug, cefaclor 375 mg/Tablet) with that of Ceclor $MR^{(R)}$ SR IAB (reference drug) and to estimate the pharmacokinetic parameters of cefaclor in healthy Korean volunteers. The bioavailability was examined on 24 healthy volunteers who received a single dose (375 mg) of each drug in the fasting state in a randomized balanced 2-way crossover design. After dosing, blood samples were collected for a period of 7 hours. Plasma concentrations of cefaclor were determined using HPLC with UV detection. The pharmacokinetic parameters $(AUC_{0-7h},\;C_{max},\;T_{max},\;AUC_{inf},\;K_e,\;t_{1/2},\;V_d/F,\;and\;CL/F)$ were calculated with non-compartmental pharmacokinetic analysis. The ANOVA test was utilized for the statistical analysis of the $T_{max}$, log-transformed $AUC_{0-7h$}$, log-transformed $C_{max},\;t_{1/2},\;V_d/F$, and $CL/F$. The ratios of geometric means of $AUC_{0-7h}\;and\;C_{max}$ between test drug End reference drug were $95.67\%\;(8.55\;vs\;8.18{\mu}g{\cdot}hr/ml)\;and\;103.86\%\;(2.85\;vs\;2.96{\mu}g/ml)$, respectively. The $T_{max}$ of test drug and reference drug was $2.56\pm0.15\;and\;2.23\pm0.13\;hrs,\;respectively.\;The\;90\%$ confidence intervals of mean difference of logarithmic transformed $AUC_{0-7h}\;and\;C_{max}$ were log0.90-log1.04 and log0.91-log1.13, respectively. It shows that the bioavailability of test drug is equivalent with that of reference drug.

• Journal of the Korean Society for information Management
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• v.31 no.4
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• pp.7-28
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• 2014

This study analyses the questions addressed to the collaborative digital reference service run by the National Library of Korea. The data consist of 661 question entries to the 'Ask a Librarian' service during first 6 months in 2014. Each entry includes average 1.17 questions, and 77.82% of the total questions are real reference in nature. Questions are analyzed by classification division, context of the questioner, desired end product, activities of librarians, and the resources used to respond them. Each category is subdivided and analyzed in detail. Results revealed interesting findings and problems, and suggestions for further endeavor are provided.

• Journal of Environmental Science International
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• v.27 no.12
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• pp.1271-1277
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• 2018

The National Environmental Specimen Bank (NESB) has been sampling and cryogenically preserving various wildlife specimens to monitor bio-accumulations of chemical pollutants since 2010. Recently, the NESB set up a plan to develop reference materials at their facility to assure the analytical quality of and validate the analytical methods for their monitoring samples. One of the crucial characteristics of reference materials is intra- and inter-bottle homogeneity. In this study, we used ANOVA for total mercury concentrations in some samples to validate their homogeneities after milling and homogenization. We examined the intra- and inter-bottle homogeneities of two cryogenically-milled samples (Korean mussel (Mytilus coruscus) and black-tailed gull's egg (Larus crassirostris). The variations in the total mercury concentrations were not significantly different intra- and inter-bottle (mussel: F=0.74, p=0.67; gull egg: F=1.96, p=0.10). Additionally, the relative standard deviations of the total mercury concentrations showed low values (mussel: 2.02%, gull egg: 1.78%). Therefore, the cryogenic-milling process statistically proves the homogeneity of the materials of mussels and sea gull eggs for chemical analysis for total mercury.

• Journal of Internet Computing and Services
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• v.23 no.6
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• pp.87-96
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• 2022

This paper is an empirical analysis as a reference model that can predict up to the maximum number of elementary school student care needs in local governments across the country. This study analyzed and predicted the characteristics of the region based on machine learning to predict the demand for elementary care in a new apartment complex. For this purpose, a total of 292 variables were used, including data related to apartment structure, such as number of parking spaces per household, and building-to-land ratio, environmental data around apartments such as distance to elementary schools, and population data of administrative districts. The use of various variables is of great significance, and it is meaningful in complex analysis. It is also an empirical case study that increased the reliability of the model through comparison with the actual value of the basic local government.

• BMB Reports
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• v.40 no.2
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• pp.226-231
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• 2007

Housekeeping genes are widely used as internal controls in a variety of study types, including real time RT-PCR, microarrays, Northern analysis and RNase protection assays. However, even commonly used housekeeping genes may vary in stability depending on the cell type or disease being studied. Thus, it is necessary to identify additional housekeeping-type genes that show sample-independent stability. Here, we used statistical analysis to examine a large human microarray database, seeking genes that were stably expressed in various tissues, disease states and cell lines. We further selected genes that were expressed at different levels, because reference and target genes should be present in similar copy numbers to achieve reliable quantitative results. Real time RT-PCR amplification of three newly identified reference genes, CGI-119, CTBP1 and GOLGAl, alongside three well-known housekeeping genes, B2M, GAPD, and TUBB, confirmed that the newly identified genes were more stably expressed in individual samples with similar ranges. These results collectively suggest that statistical analysis of microarray data can be used to identify new candidate housekeeping genes showing consistent expression across tissues and diseases. Our analysis identified three novel candidate housekeeping genes (CGI-119, GOLGA1, and CTBP1) that could prove useful for normalization across a variety of RNA-based techniques.