• Journal of the Institute of Electronics Engineers of Korea SC
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• v.41 no.6
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• pp.17-25
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• 2004

In this paper, we propose a new small swing domino logic for low-power consumption. To reduce the power consumption, both the precharge node and the output node swing the range from 0 to $V_{REF}$- $V_{THN}$, where $V_{REF}$=VDD-n $V_{THN}$ (n=1, 2, and 3). This can be done by adding the inverter structure on domino logic that allows a full swing or a small swing on its input terminal without leakage current. Compared to previous works, the proposed structure can save the power consumption of more than 30% for n=0, 1, 2, and 3 in the equation of $V_{REF}$=VDD-n $V_{THN}$. A multiplier applying the proposed domino logic has been designed and fabricated using a 0.35-${\mu}{\textrm}{m}$ n-well CMOS process under 3.3-V supply voltage. Compared with other previous works, it shows a 30% power reduction and a better feature in power-delay product.lay product.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.3
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• pp.139-144
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• 2010

In this study, we evaluated the role of apurinic/apyrimidinic endonuclease1/redox factor-1 (Ref-1) on the tumor necrosis factor-$\alpha$ (TNF-$\alpha$) induced cyclooxygenase-2 (COX-2) expression using A549 lung adenocarcinoma cells. TNF-$\alpha$ induced the expression of COX-2 in A549 cells, but did not induce BEAS-2B expression. The expression of COX-2 in A549 cells was TNF-$\alpha$ dose-dependent (5~100 ng/ml). TNF-$\alpha$-stimulated A549 cells evidenced increased Ref-1 expression in a dose-dependent manner. The adenoviral transfection of cells with AdRef-1 inhibited TNF-$\alpha$-induced COX-2 expression relative to that seen in the control cells ($Ad{\beta}gal$). Pretreatment with $10\;{\mu}M$ of SB203580 suppressed TNF-$\alpha$-induced COX-2 expression, thereby suggesting that p38 MAPK might be involved in COX-2 expression in A549 cells. The phosphorylation of p38 MAPK was increased significantly after 5 minutes of treatment with TNF-$\alpha$, reaching a maximum level at 10 min which persisted for up to 60 min. However, p38MAPK phosphorylation was markedly suppressed in the Ref-1-overexpressed A549 cells. Taken together, our results appear to indicate that Ref-1 negatively regulates COX-2 expression in response to cytokine stimulation via the inhibition of p38 MAPK phosphorylation. In the lung cancer cell lines, Ref-1 may be involved as an important negative regulator of inflammatory gene expression.

• Proceedings of the Optical Society of Korea Conference
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• 2001.02a
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• pp.124-125
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• 2001

The electro-magnetic vector equation(F=$qv{\times}B$ ; F：force, B：magnetic field, q：plus charge, v ：velocity of the charge) explains well about the rotations of electron and positron under the magnetic field[Ref.1], as in Fig.1(a). Because the electro-magnetic wave is also a motion of the alternating charge and magnetic field as in Fig.2, the force vector has all the time inwarding direction and then the wave has a rotating motion. The positron in the proton has constant charge and alternating one at the same time[Ref.2] and then the alternating charge makes the absorbing force with the alternating charge of the rotating wave ($\pi$-ray) around the nucleus[Ref.2]. (omitted)

• Proceedings of the Korean Society for Information Management Conference
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• 2012.08a
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• pp.115-119
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• 2012

본 연구의 목적은 이학분야 국내학술지 중 DOI를 기반으로 하여 인용정보를 제공하고 있는 학술지를 대상으로 피인용정보를 분석하고 WoS, Scopus와 비교를 통해 유사점과 차이점을 찾는 것이다. DOI를 등록하고 있고 WoS, Scopus에 공통으로 등재되어있는 5종의 이학분야 학술지의 CrossRef 피인용정보를 분석한 결과 논문수가 많은 2개 학술지의 인용률이 높았으며 모두 낮은 자기인용률을 보이고 있다. 전체적으로 CrossRef의 고유논문은 논문수와 인용수가 가장 큰 학술지 1종만이 11%이고 나머지 4종의 학술지는 5% 미만으로 대부분 WoS, Scopus 논문에 포함되었다. DB별 비교를 위해 3년간(2008~2010) 발행된 논문의 피인용도를 확인한 결과 모든 학술지에서 WoS의 인용률이 가장 높았고 CrossRef의 경우 레코드 수는 많지만, 전문색인DB가 아니고 참고문헌 등록이 모두 이뤄지지 않아 인용률이 가장 낮았다. 하지만 CrossRef 고유논문비율이 11%인 학술지의 경우 Scopus 보다 인용률이 높은 것으로 나타났다.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.04a
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• pp.1573-1575
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• 2011

KISTI는 CrossRef/DOI 기탁사업을 통해 학술정보생산자인 학회나 기관에게 해외유통망을 지원하는 사업을 해오고 있다. 그리고 DOI 기반의 학술논문간 인용정보 서비스인 Cited-by linking 결과를 과학 기술학회마을을 통해 논문의 인용횟수와 인용논문정보를 제공하고 있다. CrossRef에서 회원에게만 제공하는 Cited-by linking 결과를 분석해보면, KISTI에서 기탁하는 논문수가 증가함에 따라 인용논문수도 지속적으로 증가하고 있는 것을 볼 수 있다[1]. 이에 따라 Cited-by linking 결과를 학회나 기관이 쉽게 접근 할 수 있도록 KISTI 학술정보통합관리시스템에 적용하는 방안을 모색하고자 한다. 학회나 기관이 Cited-by linking결과에 쉽게 접근하여 각 학술지의 인용현황을 관리하고 그 결과 데이터를 활용하여 기존에 서비스되고 있는 정보 외에 필요한 정보를 획득할 수 있도록 지원하는 시스템이다.

• Computational Structural Engineering
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• v.17 no.2
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• pp.50-59
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• 2004

The Thunder Horse semi-submersible intended for production of hydrocarbons at Thunder Horse field in the Gulf of Mexico(GOM), Mississippi Canyon Block 778. The field is located in water depth of 1850m, 240km SE of New Orleans.(ref. Fig.1) These areas have estimated 1.5billion barrels reported. Also there are world class subsea hardwares with 15ksi Guideline less Trees, High pressure 8-12" Flow lines, Insulated Steel Catenary Risers with Flexible Connectors, 150km of Flow lines, and 100km Control & Injection Umbilicals(ref. Fig.2). (omitted)

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.241-244
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• 2008

The authors proposed a new rapid-screening method for more reasonably evaluating seismic capacities of medium and low-rise RC buildings controlled by both shear and flexure in Ref. [1]. The method proposed in Ref. [1] was based on relationships between required strengths of each failure system for ductility factors and damage degrees of overall system derived from the view-point of ductility factors. The proposed method was also verified using observed real damage data of low-rise RC buildings caused by past earthquakes. Results indicated that the methodology proposed in Ref. [1] compares well with real damages and is a useful strategy for rapidly identifying low-rise RC buildings having high potential seismic risk. In this study, in order to verify the applicability of the new methodology proposed in Ref. [1] to real RC building systems, seismic capacities of existing eleven low-rise RC buildings in Korea are evaluated based on the new method.

• Korean Journal of Food Science and Technology
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• v.25 no.2
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• pp.178-184
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• 1993

The procedure using equivalent time at reference temperature has been assessed for the estimation of kinetic parameters with experimental data. Kinetic studies of nonenzymatic browning reaction in model and food system were carried out with linearly increasing temperature method. These kinetic parameters, n, $k_{ref}$ and $E_a$ of the systems were evaluated from original data in one step by nonlinear least square regression. The one step procedure yielded efficiently accurate parameter estimation. Computer simulated data with the kinetic models were well consistent with experimental data (average correlation coefficient=0.96).

• 대한약리학회:학술대회논문집
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• 2006.10a
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• pp.112.2-112.2
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• 2006

• Korean Journal of Microbiology
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• v.54 no.2
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• pp.91-97
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• 2018

The evolutionally conserved TREX complex member, Yra1/ALY, belongs to the REF (RNA and export factor binding proteins) family of hnRNP-like proteins, which has been implicated in multiple processes including transcription, nuclear RNA stability, and mRNA export. Fission yeast, Schizosaccharomyces pombe, genome encodes two members of REF proteins. In addition to Mlo3 known previously as an mRNA export factor, there is the other REF protein, Tho4, which is predicted as a component of THO complex. Here we showed that deletion of tho4 (SPBC106.12c) gene does not inhibit both growth and nuclear mRNA export. However, overexpression of tho4 displays growth retardation and slight accumulation of $poly(A)^+$ RNA in the nucleus. Neither ${\Delta}tho4$ ${\Delta}mlo3$ nor ${\Delta}tho4$ ${\Delta}mex67$ double mutants exhibit additive growth defect. Moreover, yeast two-hybrid and co-immunoprecipitation analysis did not show that the Tho4 protein interacted with any members of TREX complex and mRNA export factor Rae1. Contrary to expectation, these observations support that the S. pombe Tho4 is not a component of TREX complex, and not directly involved in bulk mRNA export from the nucleus.