• Title/Summary/Keyword: Ref1

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Estimation on Trends of Reference Evapotranspiration of Weather Station Using Reference Evapotranspiration Calculator Software (Reference Evapotranspiration Calculator Software를 이용한 기상관측소 기준증발산 추정)

  • Choi, Wonho;Choi, Minha;Oh, Hyunje;Park, Jooyang
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.2B
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    • pp.219-231
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    • 2010
  • The Reference Evapotranspiration Calculator Software (REF-ET) supports computational guidelines for the reference evapotranspiration using seventeen FAO Penman-Monteith (PM) equations simultaneously such as the ASCE and FAO standardized forms. The REF-ET can conveniently consider missing data predictions and regional site characterizations, when reference ET is computed on monthly, daily, and hourly time steps. The applicability of the REF-ET was estimated to simulate the reference ET using hourly weather data from Seoul weather station for 29 years. The result found that the FAO24-Rd and 1957-Makk equations closely concerned with solar radiation parameter which were the most highly correlated to reference ET computed by pan coefficient. In addition, the 1957-Makk equation was identified as the most correct computational method for reference ET by analysis of bias and root mean square error. The 1957-Makk equation could predict the reference ET within the error of less than 1.06 mm/day, though all the other equations tended toward overestimation of predicting the reference ET in comparison with refecence ET of pan. The results of this study suggest that the REF-ET will be applicable to support reference ET estimation for a variety of field condition and time-scale.

Ref-1 protects against FeCl3-induced thrombosis and tissue factor expression via the GSK3β-NF-κB pathway

  • Lee, Ikjun;Nagar, Harsha;Kim, Seonhee;Choi, Su-jeong;Piao, Shuyu;Ahn, Moonsang;Jeon, Byeong Hwa;Oh, Sang-Ha;Kang, Shin Kwang;Kim, Cuk-Seong
    • The Korean Journal of Physiology and Pharmacology
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    • v.25 no.1
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    • pp.59-68
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    • 2021
  • Arterial thrombosis and its associated diseases are considered to constitute a major healthcare problem. Arterial thrombosis, defined as blood clot formation in an artery that interrupts blood circulation, is associated with many cardiovascular diseases. Oxidative stress is one of many important factors that aggravates the pathophysiological process of arterial thrombosis. Apurinic/apyrimidinic endonuclease 1/redox factor-1 (Ref-1) has a multifunctional role in cells that includes the regulation of oxidative stress and anti-inflammatory function. The aim of this study was to investigate the therapeutic effect of adenovirus-mediated Ref-1 overexpression on arterial thrombosis induced by 60% FeCl3 solution in rats. Blood flow was measured to detect the time to occlusion, thrombus formation was detected by hematoxylin and eosin staining, reactive oxygen species (ROS) levels were detected by high-performance liquid chromatography, and the expression of tissue factor and other proteins was detected by Western blot. FeCl3 aggravated thrombus formation in carotid arteries and reduced the time to artery occlusion. Ref-1 significantly delayed arterial obstruction via the inhibition of thrombus formation, especially by downregulating tissue factor expression through the Akt-GSK3β-NF-κB signaling pathway. Ref1 also reduced the expression of vascular inflammation markers ICAM-1 and VCAM-1, and reduced the level of ROS that contributed to thrombus formation. The results showed that adenovirus-mediated Ref-1 overexpression reduced thrombus formation in the rat carotid artery. In summary, Ref-1 overexpression had anti-thrombotic effects in a carotid artery thrombosis model and could be a target for the treatment of arterial thrombosis.

A Quartz Tube Based Ag/Ag+ Reference Electrode with a Tungsten Tip Junction for an Electrochemical Study in Molten Salts

  • Park, Y.J.;Jung, Y.J.;Min, S.K.;Cho, Y.H.;Im, H.J.;Yeon, J.W.;Song, K.
    • Bulletin of the Korean Chemical Society
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    • v.30 no.1
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    • pp.133-136
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    • 2009
  • A newly designed Ag/$Ag^+$ reference electrode in a quartz tube with a tungsten tip junction (W-tip-Quartz- REF) was fabricated and its electrochemical performance was compared with a conventional Pyrex tube-based Ag/$Ag^+$ reference electrode (Py-REF). The results of the electrochemical potential measurements with the W-tip-Quartz- REF and the Py-REF in the LiCl-KCl eutectic melts for a wide temperature range proved that the oxide layer on the surface of the tungsten metal tip provided a high ionic conduction. Stability of our newly designed W-tip- Quartz-REF was tested by measuring a junction potential for 12 hours at 700${^{\circ}C}$. The results of the cyclic voltammetric measurement indicated that the Ag/$Ag^+$ reference electrode in the quartz tube with a tungsten tip junction can provide a good performance for a wide temperature range.

Cytoprotective effect of rhamnetin on miconazole-induced H9c2 cell damage

  • Lee, Kang Pa;Kim, Jai-Eun;Park, Won-Hwan
    • Nutrition Research and Practice
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    • v.9 no.6
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    • pp.586-591
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    • 2015
  • BACKGROUND/OBJECTIVES: Reactive oxygen species (ROS) formation is closely related to miconazole-induced heart dysfunction. Although rhamnetin has antioxidant effects, it remained unknown whether it can protect against miconazole-induced cardiomyocyte apoptosis. Thus, we investigated the effects of rhamnetin on miconazole-stimulated H9c2 cell apoptosis. MATERIALS/METHODS: Cell morphology was observed by inverted microscope and cell viability was determined using a WelCount$^{TM}$ cell proliferation assay kit. Miconazole-induced ROS production was evaluated by fluorescence-activated cell sorting with 6-carboxy-2',7'-dichlorofluoroscein diacetate ($H_2DCF$-DA) stain. Immunoblot analysis was used to determine apurinic/apyrimidinic endonuclease 1 (APE/Ref-1) and cleaved cysteine-aspartic protease (caspase) 3 expression. NADPH oxidase levels were measured using real-time polymerase chain reaction. RESULTS: Miconazole (3 and $10{\mu}M$) induced abnormal morphological changes and cell death in H9c2 cells. Rhamnetin enhanced the viability of miconazole ($3{\mu}M$)-treated cells in a dose-dependent manner. Rhamnetin (1 and $3{\mu}M$) treatment downregulated cleaved caspase 3 and upregulated APE/Ref-1 expression in miconazole-stimulated cells. Additionally, rhamnetin significantly reduced ROS generation. CONCLUSIONS: Our data suggest that rhamnetin may have cytoprotective effects in miconazole-stimulated H9c2 cardiomyocytes via ROS inhibition. This effect most likely occurs through the upregulation of APE/Ref-1 and attenuation of hydrogen peroxide levels.

Analysis of changes in plant species and diversity after planting trees into the semi-arid desert of Hulunbuir, Inner Mongolia

  • Eui-Joo Kim;Seung-Hyuk Lee;Sung-Bae Joo;Young-Han You
    • Journal of Ecology and Environment
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    • v.47 no.4
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    • pp.177-186
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    • 2023
  • Background: Inner Mongolia, desertification is happening due to climate change and land use alterations. In order to evaluate desert restoration effectiveness, this study compares number of species and species diversity in restored (with planted trees), unrestored area, and the reference ecosystem (Ref-E, typical steppe and woody steppe). Results: The Ref-E had the most plant species (64 taxa), while the unrestored area had the fewest (5 taxa). Among restored areas (restored in 2012, 2008, 2005), older restoration sites had more species (18-42). Similarly, species richness (3.93-0.41) and diversity (1.99-0.40) were highest in the Ref-E and lowest in unrestored areas, with older restored sites having higher values. Conclusions: More plant species and diversity in older restoration areas suggest progress toward ecosystem stabilization, approaching the Ref-E. Therefore, tree planting in Inner Mongolia's Hulunbuir semi-arid desert is a successful restoration effort.

RINGS WITH REFLEXIVE IDEALS

  • Han, Juncheol;Park, Sangwon
    • East Asian mathematical journal
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    • v.34 no.3
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    • pp.305-316
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    • 2018
  • Let R be a ring with identity. A right ideal ideal I of a ring R is called ref lexive (resp. completely ref lexive) if $aRb{\subseteq}I$ implies that $bRa{\subseteq}I$ (resp. if $ab{\subseteq}I$ implies that $ba{\subseteq}I$) for any $a,\;b{\in}R$. R is called ref lexive (resp. completely ref lexive) if the zero ideal of R is a reflexive ideal (resp. a completely reflexive ideal). Let K(R) (called the ref lexive radical of R) be the intersection of all reflexive ideals of R. In this paper, the following are investigated: (1) Some equivalent conditions on an reflexive ideal of a ring are obtained; (2) reflexive (resp. completely reflexive) property is Morita invariant; (3) For any ring R, we have $K(M_n(R))=M_n(K(R))$ where $M_n(R)$ is the ring of all n by n matrices over R; (4) For a ring R, we have $K(R)[x]{\subseteq}K(R[x])$; in particular, if R is quasi-Armendaritz, then R is reflexive if and only if R[x] is reflexive.

INEQUALITIES FOR JACOBI POLYNOMIALS

  • Pyung, In Soo;Kim, Hae Gyu
    • Korean Journal of Mathematics
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    • v.12 no.1
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    • pp.67-75
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    • 2004
  • Paul Turan observed that the Legendre polynomials satisfy the inequality $P_n(x)^2-P_{n-1}(x)P_{n+1}(x)$ > 0, $-1{\leq}x{\leq}1$. And G. Gasper(ref. [6], ref. [7]) proved such an inequality for Jacobi polynomials and J. Bustoz and N. Savage (ref. [2]) proved $P^{\alpha}_n(x)P^{\beta}_{n+1}(x)-P^{\alpha}_{n+1}(x)P{\beta}_n(x)$ > 0, $\frac{1}{2}{\leq}{\alpha}$ < ${\beta}{\leq}{\alpha}+2.0$ < $x$ < 1, for the ultraspherical polynomials (respectively, Laguerre ploynomials). The Bustoz-Savage inequalities hold for Laguerre and ultraspherical polynomials which are symmetric. In this paper, we prove some similar inequalities for non-symmetric Jacobi polynomials.

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Influence of Muscle Architecture on Force Enhancement Following Muscle Lengthening (근육 구조특성과 선행 신장성 수축에 의한 항정상태 등척성 근력 증대와의 연관성에 대한 연구)

  • Lee, Hae-Dong;Lee, Jung-Hyun
    • Korean Journal of Applied Biomechanics
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    • v.17 no.3
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    • pp.61-68
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    • 2007
  • When an active muscle is stretched, its steady-state isometric force following stretch is greater than that of a purely isometric contraction as the corresponding muscle length, referred to as force enhancement (FE). The purpose of this study was to investigate possible effects of muscle architecture on the FE. While subject performed maximal isometric dorsiflexion (REF) and isometric-stretch-isometric dorsiflexion (ECC) contractions, ankle joint angle and dorsiflexion torque using a dynamometer and electromyography of the tibialis anterior and the medical gastrocnemius muscles were measure. Simultaneously, real-time ultrasound images of the tibialis anterior were acquired. Regardless of the speed of stretch of the ECC contractions. the torques produced during the isometric phase following stretch ($37.3{\pm}1.5\;Nm$ ($10{\pm}3%$ FE) and $38.3{\pm}1.5$ ($12{\pm}3%$ FE) for the ECC contractions with $15^{\circ}$/s and $45^{\circ}$/s stretch speeds, respectively) were greater than those of the REF contractions ($34.5{\pm}2.5\;Nm$). Moreover, the amount of FE was found to be stretch speed dependent. Angles of pennation ($\alpha$) during the isometric phase following stretch were the same for the REF ($15{\pm}1^{\circ}$) and the ECC ($14{\pm}1^{\circ}$(LS), $15{\pm}1^{\circ}$(LF)). During the same phase, muscle thicknesses were the same ($14.9{\pm}0.6$, and $14.9{\pm}0.5\;mm$ for the REF and the ECC contractions, respectively). For a large limb muscle, the tibialis anterior muscle, a similar amount of force enhancement was observed as did for other human skeletal muscles. Architectural variables, pennation angle and thickness, were not systematically different between the REF and ECC contractions when FE occurred. Therefore, the results of this study suggest that muscle architecture may have little influence on the production of FE.

Hydraulic Experiments of Stem Waves along a Vertical Wall due to Unidirectional Random Waves (직립벽을 따른 일방향 불규칙파의 연파실험)

  • Lee, Jong-In;Choi, Jun-Woo;Yoon, Sung-Bum
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.20 no.1
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    • pp.49-61
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    • 2008
  • This study investigates the characteristics of stem waves along a vertical wall generated by obliquely incident random waves through laboratory experiments conducted in a wave basin and numerical simulations using REF/DIF S model developed by Kirby and $\ddot{O}zkan$(1994). The investigation is focused on the effect of random waves on the propagation characteristics of stem waves and the difference or similarity between monochromatic and random waves. The results of REF/DIF S model are compared with laboratory measurements and good agreements are obtained. The relative significant wave height along a wall is almost same with monochromatic condition, but the wave pattern along normal to the wall shows a significant difference.

Patterns of Citing Korean DOI Journals According to CrossRef's Cited-by Linking and a Local Journal Citation Database

  • Seo, Tae-Sul;Jung, Eun-Gyeong;Kim, Hwanmin
    • Journal of Information Science Theory and Practice
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    • v.1 no.2
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    • pp.58-68
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    • 2013
  • Citing literature is a very important activity for scholars in writing articles. Many publishers and libraries build citation databases and provide citation reports on scholarly journals. Cited-by linking is a service representing what an article cites and how many times it cites a specific article within a journal database. Recently, information services based on DOIs (Digital Object Identifiers) have been increasing in number. CrossRef, a non-profit organization for the DOI registration agency, maintains the DOI system and provides the cited-by linking service. Recently, the number of Korean journals adopting DOI is also rapidly increasing. The Korea Institute of Science and Technology Information (KISTI) supports Korean learned societies in DOI related activities in collaboration with CrossRef. This study analyzes cited patterns of Korean DOI journal articles using CrossRef's cited-by linking data and a Korean journal citation database. This analysis has been performed in terms of publication country and the language of journals citing Korean journal articles. The results show that DOI, SCI(E) (Science Citation Index (Expanded)), and English journals are more likely to be cited internationally.