• 한국환경보건학회지
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• 제49권2호
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• pp.99-107
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• 2023

Background: Excessive alcohol consumption is at the root of serious social problems such as hangovers, liver dysfunction, and alcoholism. Objectives: This study was carried out to determine the hangover ameliorating effect of fermented rice extract and a combination of yeast-fermented powder and lysate containing aldehyde dehydrogenase (ALDH) (improved new ingredients) in an ethanol-induced rat study. Methods: The concentrations of alcohol, acetaldehyde, and malondialdehye in serum were evaluated to assess the anti-alcohol and anti-aldehyde hangover effect in two experiments, one with fermented rice extract) and a second with yeast-fermented powder and lysate, using animal studies. Results: Experiment 2 with yeast-fermented powder and lysate containing ALDH showed similar and higher activity, respectively, in reducing ethanol and acetaldehyde concentration compared with Experiment 1 with fermented rice extract. Experiment 2 also significantly reduced malondialdehyde, a type of lipid peroxide. The ALDH-related compound (ARC) lysate showed better hangover relief effect than ARC powder. Conclusions: These results indicate that ALDH-related compounds exhibit a hangover relief effect, and fermented lysate is considered to be a better candidate for hangover relief.

• Biomolecules & Therapeutics
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• 제22권3호
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• pp.260-266
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• 2014

This study evaluated the pharmacokinetic profile and therapeutic efficacy of piroxicam (PX), a long acting non-steroidal anti-inflammatory drug for the treatment of arthritis, following intra-articular (IA) injection in comparison to the pharmacokinetic profile and therapeutic efficacy of PX after intramuscular (IM) injection. In the pharmacokinetic study in rats, systemic exposure and pharmacokinetic parameters of PX after a single IA dose were compared with systemic exposure and pharmacokinetic parameters of PX after administration of the same dose IM (0.6 mg/kg). The anti-inflammatory and analgesic effects of IA PX were evaluated simultaneously in a monoiodoacetate-induced osteoarthritis rat model. The plasma PX concentration rapidly rose following IA injection, and it was comparable to the plasma PX concentration following IM injection, suggesting the rapid efflux of the drug molecule from the joint cavity. However, in the efficacy study, the IA PX administration significantly reduced the knee swelling by reducing the level of prostaglandin $E_2$ in the joint, compared to that following administration of IA vehicle and after administration of the IM PX dose. In addition, we found that the anti-inflammatory and anti-nociceptive efficacies of IA PX were synergistically increased upon co-treatment with hyaluronic acid (HA), a potent agent for the treatment of osteoarthritis, at the weight ratio of 1:1 or 1:2, and these effects were more pronounced than those following administration of HA or PX alone. In conclusion, this study demonstrated the efficacy of the IA use of PX alone and/or in combination with HA in osteoarthritis.

• 한국세라믹학회지
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• 제51권4호
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• pp.367-373
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• 2014

In this study, the reducing agent hydrazine and precipitator NaOH were used with $NiCl_2$ as a starting material in order to compound Ni-based material with spherical nano characteristics; resulting material was used as an anode for SOFC. Synthetic temperature, pH, and solvent amounts were experimentally optimized and the synthesis conditions were confirmed. Also, a 0 ~ 0.15 mole ratio of metal(Co, Fe) was alloyed in order to increase the catalyst activation performance of Ni and finally, spherical nano $Ni_{(1-x)}-M_{(x=0{\sim}0.15)}$(M = Co, Fe) alloy materials were compounded. In order to evaluate the catalyst activation for hydrocarbon fuel, fuel gas(10%/$CH_4$+10%/Air) was added and the responding gas was analyzed with GC(Gas Chromatography). Catalyst activation improvement was confirmed from the 3% hydrogen selectivity and 2.4% methane conversion rate in $Ni_{0.95}-Co_{0.05}$ alloy; those values were 4.4% and 19%, respectively, in $Ni_{0.95}-Fe_{0.05}$ alloy.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 하계학술대회 논문집 Vol.9
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• pp.54-54
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• 2008

$Eu^{2+}$, $Nd^{3+}$ co-doped $BaAl_2O_4$ are known as a long afterglow phosphor. We found that $Eu^{2+}$-doped $BaAl_2O_4$ showed ptotoconductivity in the range of UV and visual light. In this study, $BaAl_2O_4$:Eu thin film has been prepared by RF sputtering method and a sensing characteristics to UV and visual light was performed. Only $Eu^{2+}$ and $Nd^{3+}$ co-doped $BaAl_2O_4$ powders and targets for deposition were prepared by a convention solid state method, and the deposition was performed in a reducing $H_2$-Ar mixture gas on Si substrates. The observation of crystalline phase and morphology of the sputtered film were performed using XRD, EDX. The photoluminescence and photocurrent to UV and visual light were measured simultaneously using 300W-Xe solar simulator as a light source. It was confirmed that the photocurrent induced by irradiation of light showed a linear relationship to the light intensity.

• 한국해양환경ㆍ에너지학회지
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• 제9권3호
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• pp.148-153
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• 2006

본 연구는 선박에서 배출되는 배기가스의 농도 측정, 연소효율 평가와 국제해사기구에서 권장하는 인덱싱 방법의 검토를 통해 이산화탄소 규제관련 대응전략 수립을 위한 기초자료 확보에 목적을 둔다. 평가된 평균 연소효율은 새 엔진의 경우 98%, 신조선의 경우 96.5%로 조사되었다. 연소효율은 엔진 및 선박의 노후로 점점 감소할 것으로 예상되며, 연소효율이 높으면 배기가스 중에 이산화탄소의 농도가 증가하고 연소효율이 낮으면 불완전연소 생성물의 방출이 증가되기 때문에 문제가 된다. 유해 오염물질을 방출하지 않고 가장 효율적으로 이산화탄소를 제어하기 위해 연료 대체, 연료 저소모 엔진 개발 및 경제적 선속 유지를 위한 해운사간 협조가 필요할 것이다. 국제해사기구의 인덱싱 방법을 검토한 결과, 보다 실제에 가까운 이산화탄소 배출량을 산출하기 위해서는 사용 연료의 탄소 함량을 조사하고 국제해사기구의 권장 수치와 비교하여 지수화 작업을 진행하는 것이 바람직한 것으로 나타났다.

• 콘크리트학회논문집
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• 제21권1호
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• pp.85-92
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• 2009

콘크리트는 생산과정에서 다량의 이산화탄소를 배출하는 시멘트를 사용하기 때문에 반친환경적 재료로 인식되고 있다. 하지만 콘크리트는 사용기간 중 탄산화 과정을 통하여 대기중의 이산화탄소를 흡수한다. 이에 본 연구에서는 기존문헌 고찰을 통하여 1) 콘크리트 내 탄산화 가능한 물질의 농도, 2) 탄산화된 콘크리트의 체적, 3) 이산화탄소 분자량을 이용, 탄산화를 통한 콘크리트의 이산화탄소 흡수량의 정량적 산출 방법을 제시하였다. 또한 콘크리트 생산에 사용되는 재료들의 이산화탄소 배출량 자료를 이용하여 단위 콘크리트 생산에 따른 이산화탄소 배출량을 정량적으로 산출하였다. 이러한 콘크리트의 이산화탄소 흡수량 및 배출량의 정량적 산출방법을 이용하여 실제 사용중인 아파트 건축물 1동을 대상으로 하여 콘크리트의 생산에 따른 배출량과 사용기간에 따른 이산화탄소 흡수량을 정량적으로 산출하여 이산화탄소의 배출량-흡수량 평가를 실시하였다. 그 결과 건축물을 40, 60, 80년 사용시, 사용된 콘크리트의 이산화탄소 배출량 대 흡수량의 비율이 3.65, 4.47, 5.18%로 나타났다. 본 연구는 콘크리트 생산 및 사용에 따른 이산화탄소 배출량-흡수량의 정량적 산정방법에 연구의 목적을 두었으며 이산화탄소 배출량-흡수량 평가 결과 구조물을 80년 사용할 시 약 5.18%로 그 값이 미비하였으나 시멘트의 혼화재 치환율 증가를 통한 배출량 저감과 탄산화 체적 증가를 통한 이산화탄소 흡수량 증가를 통해 배출량-흡수량을 향상시킬 수 있으며, 향후 콘크리트의 이산화탄소 배출량-흡수량 평가에 본 연구의 방법이 유용하게 활용될 수 있을 것으로 판단된다.

• 한국식품저장유통학회지
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• 제19권3호
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• pp.420-427
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• 2012

본 연구는 옻나무 추출물(Rhus verniciflua Stokes extract, RVSE)의 침지가 가스조절포장(modified-atmosphere packaging, MAP)으로 저장한 한우고기 스테이크의 총환원력, 단백질산화 및 육색소산화에 미치는 영향을 구명하고자 실시하였다. 시료(Hanwoo longissimus muscle)는 옻나무 추출물의 침지 여부에 따라 처리한 후 high oxygen-MAP(HOMAP; 75% $O_2$+20% $CO_2$+5% $N_2$)와 low oxygen-MAP (LOMAP; 0% $O_2$+20% $CO_2$+80% $N_2$)으로 포장하여 $4^{\circ}C$에서 9일 동안 저장하였다. 총환원력은 RVSE의 침지에 의해 증가되었으며(p<0.05), LOMAP에 의해 저장기간 동안 높게 유지되었다. Carbonyl 함량은 RVSE의 침지와 LOMAP에 의해 억제되었다. Metmyoglobin의 축적은 RVSE의 침지에 의해 증가되었으나, HOMAP에 의해 낮게 유지되었다. 이와 반대로 oxymyoglobin에 의한 적색 강도의 지표인 R630-R580은 RVSE의 침지에 의해 감소되었던 반면, HOMAP에 의해 높게 유지되었다. 명도($L^*$), 적색도($a^*$) 및 chroma($C^*$)는 RVSE의 침지에 의해 감소되었으나, HOMAP에 의해 높게 유지되었다. 반면에 hue-angle($H^{\circ}$)은 RVSE의 침지에 의해 증가되었으나, HOMAP에 의해 낮게 유지되었다. 따라서 RVSE의 침지는 한우고기 스테이크의 총환원력과 단백질산화 안정성을 증가시켰으나, 육색소산화 안정성 감소시켰다. 또한 HOMAP는 총환원력과 단백질산화 안정성을 감소시켰으나, 육색소산화 안정성은 증가시켰다.

• 한국수소및신에너지학회논문집
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• 제21권1호
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• pp.26-34
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• 2010

The electrocatalystic prperties of Pt-Co and Pt-Ni with heteropolyacids (HPAs) entrapped in covalently cross-linked sulfonated poly(ether ether ketone) (CL-SPEEK)/HPA membranes were investigated for water electrolysis. The HP As, including molybdophosphoric acid (MoPA), and tungstophosphoric acid (TPA) were both used as membrane additives and electrocatalysts. The membrane electrode assembly (MEA) was prepared by a nonequilibrium impregnation-reduction (I-R) method. $Pt(NH_3)_4Cl_2$, $NiCl_2$ and $CoCl_2$ as electrocatalytic materials and $NaBH_4$ as reducing agent were used. I order to enhance electrocatalytic activity, the catalyst layer prepared above was electrodeposited (Dep) with HP A. Surface morphologies and physico-chemical properties of MEA were investigated by means of SEM, EDX and XRD. The electrocatalytic properties of composite membranes such as the cell voltage and coulombic charge in CV were in the order of magnitude: CL-SPEEK/MoPA40 (wt%) > CL-SPEEK/TPA30 > Nafion117. In the optimum cell applications for water electrolysis, the cell voltage of Pt/CL-SPEEK-MoPA40/Pt-Co (Dep-MoPA) and Pt/CL-SPEEK-TPA30/Pt-Co (Dep-TPA) was 1.75 Vat $80^{\circ}C$ and $1\;A/cm^2$ and voltage efficiency was 87.1%. Also, the observed activity of Pt-Co (84:16 atomic ratio by EDX) is a little higher than that of Pt-Ni (86: 14). The current density peak of electrodeposited electrodes were better a little than those of unactivated electrodes based on the same membranes.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2008년도 춘계학술대회 논문집
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• pp.202-205
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• 2008

Anaerobic digestion(AD) is the most promising method of treating and recycling of different organic wastes, such as OFMSW, household wastes, animal manure, agro-industrial wastes, industrial organic wastes and sewage sludge. During AD, i.e. degradation in the absence of oxygen, organic material is decomposed by anaerobes forming degestates such as an excellent fertilizer and biogas, a mixture of carbon dioxide and methane. AD has been one of the leading technologies that can make a large contribution to producing renewable energy and to reducing $CO_2$ and other GHG emission, it is becoming a key method for both waste treatment and recovery of a renewable fuel and other valuable co-products. A classification of the basic AD technologies for the production of biogas can be made according to the dry matter of biowaste and digestion temperature, which divide the AD process in wet and dry, mesophilic and thermophilic. The biogas produced from AD plant can be utilized as an alternative energy source, for lighting and cooking in case of small-scale, for CHP and vehicle fuel or fuel in industrials in case of large-scale. This paper provides an overview of the status of biogas production and utilization technologies.

• 한국지역사회생활과학회지
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• 제15권2호
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• pp.65-71
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• 2004

Many studies have shown that Letinus edodes has some effect on reducing blood pressure and lipid levels of animals with high pressure and hyperlipidemia. The cost of Letinus edodes varies depending on when it is harvested, and yet there has been no data collected on the bio-functional effects of Letinus edodes harvested at different times. This study was conducted to investigate the supplementary effects of Letinus edodes harvested at different times on blood pressure and blood lipid levels of hypertensive rats. Three kinds of experimental diets - control (CO), early harvested Lentinus deodes (EL), and late harvested Lentinus edodes (LL) - were supplied to spontaneously hypertensive rats (SHR) for eight weeks. The diet intake, body weight, organ weight, and serum lipid levels were subsequently measured. No significant difference was observed in diet intake and in the respective weights of the body, liver, and epididymal fat pad among experimental groups. The levels of systolic and disastolic blood pressure were significantly lower in the LE and LL groups than those in the CO group; and the concentration of serum total cholesterol was also lower in the LE and LL groups than in the CO group. These results confirm that Lentinus edodes reduces blood pressure levels and serum total cholesterol concentration in spontaneously hypertensive rats. But the effects of Lentinus edodes did not differ significantly based on whether the Lentinus edodes was harvested early or late.