• 한국광학회지
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• 제13권6호
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• pp.548-553
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• 2002

유도 브릴루앙 산란 위상공액 거울(SBS-PCM)을 이용한 Nd:YAG 레이저 발진기를 구성하고 특성을 조사하였다. SBS-PCM은 SBS-cell과 렌즈계의 조합으로 구성되어 있다. Q-switcher를 사용하지 않은 경우, SBS-cell이 SBS-PCM으로 작용하지 않은 것을 확인하였고, Cr:YAG(T=50%) Q-switcher가 사용된 경우는 SBS-cell이 SBS-PCM으로 작용하였다. 이 경우 에너지 출력특성은 SBS-PCM의 유무에 관계엾이 차이가 없으나, 출력의 빔프로파일은 크게 향상되었다. 이를 설명하기 위해 초평면에서의 세기에 따른 반사율차이를 이용한 간단한 공간주파수 여과모형을 제시하고 시뮬레이션 하였다.

• Elastomers and Composites
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• 제49권3호
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• pp.239-244
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• 2014

용매를 사용하지 않고 실리카와 실란커플링제의 반응을 투과 방식 휴리에 변환 적외선 분광법(FTIR)과 열중량 분석법(TGA)을 이용하여 조사하였다. 실란커플링제로 bis[3-(triethoxysilylpropyl) tetrasulfide] (TESPT)를 사용하였다. 미반응 TESPT를 제거한 후, FTIR로 화학 결합 형성을 분석하였고 TGA로 반응한 TESPT 함량을 결정하였다. 커플링제의 함량이 증가할수록 실리카에 결합한 커플링제의 양이 증가하였으나, 커플링제를 과량으로 첨가하면 커플링제 간의 축합반응에 의해 올리고머를 형성하였다. 실리카와 커플링제 그리고 고무의 결합을 확인하기 위하여 개질 실리카와 저분자량 액상 BR을 반응시켜 실리카-커플링제-BR 모델 복합체를 제조하여 화학 결합 형성을 조사하였다. 미반응 고무는 용매를 사용하여 제거하였고 FTIR과 TGA로 분석하였다. BR은 개질 실리카의 커플링제와 반응하여 화학 결합을 형성하였다. 실리카-커플링제-BR의 화학 결합 형성으로 인해 실리카 표면의 극성은 크게 낮아졌고 실리카 입자 크기는 커지는 효과를 보였다.

• 한국농공학회논문집
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• 제59권1호
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• pp.57-70
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• 2017

In this study, we evaluated daily root zone soil moisture dynamics and agricultural drought using a near-surface soil moisture data assimilation scheme with Soil Moisture Active & Passive (SMAP, $3km{\times}3km$) soil moisture footprints under different hydro-climate conditions. Satellite-based LANDSAT and MODIS image footprints were converted to spatially-distributed soil moisture estimates based on the regression model, and the converted soil moisture distributions were used for assessing uncertainties and applicability of SMAP data at fields. In order to overcome drawbacks of the discontinuity of SMAP data at the spatio-temporal scales, the data assimilation was applied to SMAP for estimating daily soil moisture dynamics at the spatial domain. Then, daily soil moisture values were used to estimate weekly agricultural drought based on the Soil Moisture Deficit Index (SMDI). The Yongdam-dam and Soyan river-dam watersheds were selected for validating our proposed approach. As a results, the MODIS/SMAP soil moisture values were relatively overestimated compared to those of the TDR-based measurements and LANDSAT data. When we applied the data assimilation scheme to SMAP, uncertainties were highly reduced compared to the TDR measurements. The estimated daily root zone soil moisture dynamics and agricultural drought from SMAP showed the variability at the sptio-temporal scales indicating that soil moisture values are influenced by not only the precipitation, but also the land surface characteristics. These findings can be useful for establishing efficient water management plans in hydrology and agricultural drought.

• The Korean Journal of Physiology and Pharmacology
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• 제19권5호
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• pp.467-472
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• 2015

Histone deacetylase (HDAC) has been recognized as a potentially useful therapeutic target for cardiovascular disorders. However, the effect of the HDAC inhibitor, trichostatin A (TSA), on vasoreactivity and hypertension remains unknown. We performed aortic coarctation at the inter-renal level in rats in order to create a hypertensive rat model. Hypertension induced by abdominal aortic coarctation was significantly suppressed by chronic treatment with TSA (0.5 mg/kg/day for 7 days). Nicotinamide adenine dinucleotide phosphate-driven reactive oxygen species production was also reduced in the aortas of TSA-treated aortic coarctation rats. The vasoconstriction induced by angiotensin II (Ang II, 100 nM) was inhibited by TSA in both endothelium-intact and endothelium-denuded rat aortas, suggesting that TSA has mainly acted in vascular smooth muscle cells (VSMCs). In cultured rat aortic VSMCs, Ang II increased p66shc phosphorylation, which was inhibited by the Ang II receptor type I ($AT_1R$) inhibitor, valsartan ($10{\mu}M$), but not by the $AT_2R$ inhibitor, PD123319. TSA ($1{\sim}10{\mu}M$) inhibited Ang II-induced p66shc phosphorylation in VSMCs and in HEK293T cells expressing $AT_1R$. Taken together, these results suggest that TSA treatment inhibited vasoconstriction and hypertension via inhibition of Ang II-induced phosphorylation of p66shc through $AT_1R$.

• Journal of Ginseng Research
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• 제34권3호
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• pp.198-204
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• 2010

Korean ginseng (Panax ginseng C.A. Meyer) preserved in syrup, known as ginseng Jung Kwa (GJK), is a popular traditional snack in Korea. We investigated the effects of heat processing time on total phenolic content and antioxidant capacity of GJK. Water extract was prepared from GJK with different heat processing times, 3 hours (GJK-3), 6 hours (GJK-6), or 12 hours (GJK-12), with sonication for 2 hours. The GJK extract contained total phenolic content in the following order: GJK-12 (2.28%)>GJK-6 (1.57%)>GJK-3 (1.29%). Both the peroxy and hydroxyl radical-scavenging activity and cellular antioxidant capacity of GJK extract was significantly enhanced with increasing heat processing time. The hydroxyl radical-scavenging activity of GJK-12 extract was greater than that of the GJK-3 and GJK-6 extracts, consistent with metal chelating capacity and reducing capacity. In a cellular model, the GJK extract effectively reduced 2,2'-azobis(2-amidinopropane) dihydrochloride, $Cu^{2+}$-, and $H_2O_2$-induced oxidative stress, with GJK-12 and GJK-6 extracts demonstrating greater cellular antioxidant capacity than the GJK-3 extract. These results suggest that heat processing time can contribute to the antioxidant capacity of GJK and that GJK extract may have the potential to be used as an effective dietary antioxidant to prevent oxidative stress-related diseases.

• 전력전자학회논문지
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• 제16권6호
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• pp.533-541
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• 2011

본 논문에서는 PSCAD/EMTDC 프로그램을 통해 제주 80kV Pilot HVDC 시스템을 구현하고 제어기를 모델링하였다. ac 계통 연계 시뮬레이션을 위해 제주 ac 계통을 축약하였으며, dc 계통 시뮬레이션을 위해 컨버터 변압기, 고조파 필터 및 dc 전송선로의 설계 파라미터를 적용하였다. HVDC 제어기는 컨버터의 운전모드에 따라 인버터 제어기와 정류기 제어기로 나뉘며, 인버터 제어기는 전류제어기, 전압제어기, 소호각 제어기로 구현하였고, 정류기의 제어기는 전류제어기 및 전압제어기로 구현하였다. 인버터와 컨버터의 V-I 특성곡선에 VDCOL을 적용하여 전압에 따른 전류의 의존 특성을 반영하였다. 제어기의 단위 응답, ac 계통 단상 지락 고장, 3상 지락 고장에 대해 시뮬레이션하여 설계한 제어기의 정상상태 및 과도상태시 동특성을 검증하였다.

• 한국전산구조공학회논문집
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• 제29권6호
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• pp.547-554
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• 2016

본 논문에서는 개구부가 있는 철근콘크리트 전단벽의 전단강도를 산정하기 위해 수정압축장 이론에 기반을 둔 비선형 유한요소해석을 수행하였다. 철근콘크리트 전단벽의 전단강도에서 개구부의 영향을 분석하기 위해 개구부 주변 정착길이 내 철근들에 대한 철근비를 해석 모델에서 감소시켰으며, 비선형 유한요소해석은 기존 문헌에 제시된 시험 결과와의 비교를 통해 검증되었다. 실험 결과와의 비교를 통해 개구부 주변 철근들의 정착길이를 고려한 비선형 유한요소해석의 경우 철근콘크리트 전단벽의 전단강도 예측에 있어 개구부의 영향을 잘 반영한 것으로 나타났다. 이에 반해, 현행 설계기준들은 전단강도를 합리적으로 예측하지 못하는 것으로 나타났다. 본 논문은 향후 기존 철근콘크리트 전단벽에 개구부를 설치하는 경우, 전단벽의 합리적인 전단강도 예측에 유용할 것으로 기대된다.

• Archives of Pharmacal Research
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• 제21권5호
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• pp.531-536
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• 1998

We had previously reported that the protective effect of taurine against indomethacin-induced gastric mucosal injury was due to its antioxidant effects, which inhibited lipid peroxidation and neutrophil activation. In this study, we examined the effect of taurine on reducing the inflammatory parameters of trintrobenzene sulfonic acid (TNBS)-induced inflammatory bowel disease (IBD) in rats. In order to induce IBD, ethanolic TNBS was given to rats intracolonically. Then they received 500 mg/kg.day of taurine orally and were sacrificed one week after IBD induction. While ulceration and inflammation of distal colon with formation of granuloma in the vehicle-treated IBD rats two days after administration of TNBS were observed, treatment with taurine ameliorated colonic damage and decreased the incidence of diarrhea and adhesion. also, colon weight as an index of tissue edema, which was mardedly increased in the IBD rats, became significantly lower after administration of TNBS were observed, treatment with taurine ameliorated colonic damage and decreased the incidence of diarrhea and adhesion. Also colon weitht as an index of tissue edema, which was markedly increased in the IBD rats, became significantly lower after taruine treatment. Myeloperoxidase (MPO) activity in the vehicle-treated IBD rats was substantially increased, compared with that of normal control. the taurine-treated animals significantly reduced MPO activity (35% lower) when compared with that of the vehicle-treated animals. Taurine treatment decreased both basal and formyl-methionyl leucyl phenylalanine-stimulated reactive oxygen generation from colonic tissue in the IBD rats. These results suggest that the administration of taurine reduce the inflammatory parameters in this IBD rat model by increasing defending capacity against oxidative damage.

• Archives of Pharmacal Research
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• 제29권5호
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• pp.348-353
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• 2006

In this study, a 40% ethanol extract of Chinese yam flour (Dioscoreae rhizoma), containing $177{\pm}58{\mu}g/mL$ of dioscin, was tested in order to evaluate its pharmacological effects on the gastrointestinal tracts of Sprague-Dawley rats. Via the ingestion of the Chinese yam extract, the secretion of gastric acid was suppressed in the rats, and gastrointestinal motility increased by as much as 10%. The fecal quantity of rats fed on the Chinese yam extract also increased, by more than 40% as compared with that of the controls. The Chinese yam extract was found not to affect the growth of normal intestinal bacteria. However, a great deal of lactose-fermenting bacteria was observed in the fecal samples of rats fed for 6 weeks on 2% Chinese yam extract. This finding would appear to suggest that Chinese yam extract not only induces an improvement in digestive capability, but also affects the conversion of some intestinal flora to helpful bacteria. Our serochemical analyses indicated that serum glucose, neutral lipid, and total cholesterol levels were reduced to some degree by long-term feeding on Chinese yam extract. This finding bolsters the notion that Chinese yam extract may prove helpful as a digestion-aiding agent for patients suffering from hyperglycemia or hyperlipidemia.

• 한국ITS학회 논문지
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• 제13권3호
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• pp.25-37
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• 2014

해외 주요 도시에서 운영되고 있는 트램은 도시부의 교통혼잡과 대중교통의 수송분담율 감소 문제, 환경문제를 해결할 수 있는 대중교통 수단으로 인식되어 우리나라의 각 지방자치 단체에서 시스템 도입을 진행 중에 있다. 본 연구에서는 기존 신호운영 체계에서 트램을 효율적으로 운영하기 위한 능동식 트램 우선신호 전략을 개발하였다. 트램 우선신호를 수행하기 위한 시스템을 구성하고, 트램 정류장의 정차시간을 제어를 통해 트램의 교차로 무정차 통과를 구현하는 알고리즘을 개발하였으며, 대향방향의 트램차량을 고려하여 트램의 신호교차로 연속통행을 구현하였다. 또한 트램의 교차로 도착시간에 따라 정류장의 정차시간을 최소화하기 위한 능동식 우선신호 전략을 선택함으로서 신호제어 효과를 극대화 하였다. 개발된 신호제어전략을 평가하기 위해서 VISSIM 모형의 API 기능을 이용하여 트램 우선신호 제어전략을 구현하여 신호제어 효과를 분석한 결과, 트램차량의 신호교차로 정지수와 통행시간이 감소했음을 확인하였고, 일반차량도 트램 우선신호에 따른 지체증가가 거의 나타나지 않음을 확인하였다.