• Archives of Pharmacal Research
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• v.27 no.5
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• pp.512-517
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• 2004

The structural relationship of 16 asiatic acid (AA) derivatives, including AA and asiaticoside (AS) to cytotoxicity and anti-hepatofibrotic activity in HSC-T6 cells, were investigated. Cytotoxicities of AA derivatives varied from 5.5 $\mu$M to over 2000 $\mu$M of $IC_{50}$/ depending on AA functional group modifications. Substituting the hydroxyl group at the C(2) to N≡C and substituting bulky groups for dihydroxyl groups at (3), (23) of the A-ring increased the cytotoxicity, but keto group at C(11) and benzoyl ester at C(2) were greatly reduced it. Modification of the carboxylic acid group at C28 also reduced the cytotoxicity. The collagen synthesis determined by hydroxyproline content in the cells was inhibited from a maximum of 48% (Zlx-i-85 and 87) to 15% (AS) by AA derivatives. The anti-hepatofibrotic effect of these compounds might be due to the reduced expression of prolyl 4-hydroxylase $\alpha$ and $\beta$ subunits and TIMP2. However, the inhibition of collagen by asiaticoside derivatives did not show any structural-activity relationship.

• Journal of the Korean Society for Marine Environment & Energy
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• v.20 no.2
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• pp.84-90
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• 2017

In this research, a three-dimensional Computational Fluid Dynamics(CFD), scour characteristics around monopile was grasped and the effect of circular ring type scour protection on reducing protection was assessed. When Torsethaugen(1975) found that the scour area and its depth were coincided quantitatively On the ground of previous findings, after scour was assessed in terms of sea current velocity, we also found that the tendency of maximum scour depth and its width were increased as the sea current velocity was increased. The experiments were performed by attaching ring-circular typed scour protection under the bottom in order to reducing scour around the constructs of monopile type and showed reduced scour approximately by 68.5%. In addition, there were reduction of downward flow and bottom velocities, suggesting that scour protection reduce the effect of downward flow on scour.

• Journal of the Korean Society of Propulsion Engineers
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• v.11 no.1
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• pp.11-17
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• 2007

Effects of combustion chamber design on combustion stability characteristics of a full-scale gas generator were studied experimentally. Thirty seven double-swirl injectors with recess number of 1.5 were distributed in the injector head, which significantly influences combustion performance. The characteristics of combustion stability were inspected by the parametric variations such as changing length and diameter of the combustion chamber and installing a turbulence ring. The experimental result shows that as the effective length of the combustion chamber decreased, an instability frequency took place in a high-frequency region, and the amplitude of the dynamic pressure generally diminished and could be reduced to the unharmful level. However, the dynamic pressure fluctuation in the region of longitudinal resonant frequency could not be suppressed perfectly.

• Journal of Power System Engineering
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• v.13 no.6
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• pp.95-101
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• 2009

The generator for gas turbine power generation consists of the rotor which generates magnetic field, the winding coil which is the path for the field current and the wedge and retaining ring which prevents the radial movement of the coil. Relatively severe deformation was observed at the coil end section during the inspection of the generator for peaking-load operation, and the thermal-electricity and the centrifugal force were evaluated by the simple modeling of the windings to find the cause. But the simulation stress was not sufficient to induce the coil plastic deformation. The analysis result seems to be applicable to the base-load generators which runs continuously without shut down up to a year, but there had been more deformation than simulated for the generator which is started up and shut down frequently. The cause of the coil deformation was the restriction of the expansion and shrinkage. The restriction occurs when the winding coil shrinks, and the stress overwhelms the yield stress and cause the plastic deformation. The deformation is accumulated during the start-ups and shut-downs and the thermal growth occurs. The factors which induce the coil restriction during the expansion and shrinkage should be reduced to prevent the unallowable deformation. The resolutions are cutting off the field current earlier during the generator shut-down, modifying the coil end section to remove the stress concentration and making the insulation plate inserted between the coil end section and the retaining ring have the constant thickness.

• Textile Coloration and Finishing
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• v.11 no.5
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• pp.44-54
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• 1999

Poly(ethylene 2,6-naphthalate), PEN, is a relatively well-known polymer used for engineering purposes. Naphthalene ring provides rigidity to the polymer backbone, thus, it elevated the glass transition temperature and enhanced mechanical properties. The structure and properties of PEN affect a processing conditions severely, and the high-thermal stability have been had a poor thermal processibility. Hence, the basic mechanism of solvent drawing, is very much the same as that of thermal drawing from glassy state since both involve the inducement of segmental mobility. The former achieves the goal by use of chemical energy, and the latter does so by use of thermal energy. Generally, the sorption of the solvent by the polymer has a plasticizing effect, and leads to a lowering of the glass transition temperature, $T_g$. In this paper, the dynamic viscoelasticity behavior in liquid-drawing process of an unoriented amorphous PEN films were investigated using Rheovibron. The results are as follows ： (1) For the drawing in silicone oil, the drawing below $T_g$. had $\alpha{2}$-dispersion due to an inhomogeneous taut structure. (2) For the drawing in water, the inhomogeneous taut structure reduced by the effect of plasticization even below $T_g$. (3) For the drawing in butanol, the only aliphatic segment in PEN have some molecular mobility but the mobility of the aromatic segment having naphthalene ring is nearly impossible. (4) For the drawing in dioxane/water mixing solvent, the solvent effect is complementary each other and accordingly the entire molecular conformation have stable state. (5) For the drawing in dioxane/butanol mixing solvent, the inhomogeneity of the taut structure and the aromatic segment increase with increasing the temperature and this tendencies correspond with that of the draw ratio.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.4
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• pp.72-78
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• 2009

This paper proposes a low phase noise ring voltage controlled oscillator(VCO) with a standard $0.13{\mu}m$ CMOS process for PLL circuit using the VCO-gain-controlled Delay cell. The proposed Delay cell architecture with a active resistor using a MOS transistor. This method can reduced a VCO gain so that improve phase noise. And, Delay cell consist of Wide-Swing Cascode current mirror, Positive Latch and Symmetric load for low phase noise. The measurement results demonstrate that the phase noise is -119dBc/Hz at 1MHz offset from 1.9GHz. The VCO gain and power dissipation are 440MHz/V and 9mW, respectively.

• Journal of the Korean Electrochemical Society
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• v.12 no.1
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• pp.54-60
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• 2009

The redox characteristics of 2-arylaldehydehydrazono-3-phenyl-5-substituted-2, 3-dihydro-1, 3, 4-thiadiazoles (1a-h) have been investigated in nonaqueous solvents such as 1, 2-dichloroethane (DCE), dichloromethane (DCM), acetonitrile (AN), Tetrahydrofuran (THF), and dimethylsulfoxide (DMSO) at platinum electrode. Through controlled potential electrolysis, the oxidation and reduction products of the investigated compounds had been separated and indentified. The redox mechanism had been suggested and proved. It had been found that all the investigated compounds were oxidized in two irreversible one-electron processes following the well-known pattern of The EC-mechanism; the first electron loss gives the corresponding cation-radical which is followed by proton removal from the ortho-position in the N-phenyl ring forming the radical. The obtained radical undergoes a second electron uptake from the nitrogen in the N = C group forming the unstable intermediate (di-radical cation) which undergoes ring closure forming the corresponding cation. The formed cation was stabilized in solution through its combination with a perchlorate anion from the medium. On the other hand, these compounds are reduced in a single two-electron process or in a successive two one-electron processes following the well known pattern of the EEC-mechanism according to the nature of the substituent; the first one gives the anion-radical followed by a second electron reduction to give the dianion which is basic enough to abstract protons from the media to saturate the (C = O) bond.

• Journal of IKEEE
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• v.13 no.3
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• pp.72-79
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• 2009

This paper describes a compact microstrip active antenna with dual polarization. The antenna, receiving both a left-hand circularly polarized wave and a right-hand circularly polarized wave, has a function of polarization diversity. A square-shaped empty room is located on the inside of the microstrip radiator so that the size has been reduced. And slots are added around feeding point to improve input matching. Also, amplifier and switching circuitry are placed at the empty room to increase antenna gain and to select one of the circular polarizations, respectively. The proposed antenna has been applied to GPS(global positioning system). The measurement results show that it has 10dB-impedance bandwidth, 3dB axial bandwidth of about 50MHz, 3dB beamwidth of 90degree, and gain of 13dBi, respectively, for RHCP. Also, it has 3dB axial bandwidth of about 50MHz, 3dB beamwidth of 84 degree, and gain of 12dBi, respectively, for LHCP.

• Journal of the Korean Mathematical Society
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• v.55 no.6
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• pp.1381-1388
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• 2018

Let ${\Delta}$ be a simplicial complex, $I_{\Delta}$ its Stanley-Reisner ideal and $K[{\Delta}]$ its Stanley-Reisner ring over a field K. Assume that ${\Gamma}(R)$ denotes the zero-divisor graph of a commutative ring R. Here, first we present a condition on two reduced Noetherian rings R and R', equivalent to ${\Gamma}(R){\cong}{\Gamma}(R{^{\prime}})$. In particular, we show that ${\Gamma}(K[{\Delta}]){\cong}{\Gamma}(K^{\prime}[{\Delta}^{\prime}])$ if and only if ${\mid}Ass(I_{\Delta}){\mid}={\mid}Ass(I_{{{\Delta}^{\prime}}}){\mid}$ and either ${\mid}K{\mid}$, ${\mid}K^{\prime}{\mid}{\leq}{\aleph}_0$ or ${\mid}K{\mid}={\mid}K^{\prime}{\mid}$. This shows that ${\Gamma}(K[{\Delta}])$ contains little information about $K[{\Delta}]$. Then, we define the squarefree zero-divisor graph of $K[{\Delta}]$, denoted by ${\Gamma}_{sf}(K[{\Delta}])$, and prove that ${\Gamma}_{sf}(K[{\Delta}){\cong}{\Gamma}_{sf}(K[{\Delta}^{\prime}])$ if and only if $K[{\Delta}]{\cong}K[{\Delta}^{\prime}]$. Moreover, we show how to find dim $K[{\Delta}]$ and ${\mid}Ass(K[{\Delta}]){\mid}$ from ${\Gamma}_{sf}(K[{\Delta}])$.

• Polymer(Korea)
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• v.37 no.5
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• pp.606-612
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• 2013

Glycidol-poly(lactide) (Gly-PLA) were synthesized via L-lactide ring opening polymerization with glycidol as an initiator and $Al(O-i-Pr)_3$ catalyst. The structure of Gly-PLA was analyzed and successfully confirmed by 1H NMR. The OH group of glycidol in Gly-PLA was absent according to the $^1H$ NMR analysis, indicating that the terminal OH group of glycidol successfully served as an initiator in the L-lactide polymerization. The solution and bulk polymerizations of L-lactide with glycidol were performed to examine the effect of L-lactide/glycidol molar ratio, polymerization temperature and time on the molecular characteristics of Gly-PLA. The conversion and molecular weight increased with an increase in L-lactide/glycidol molar ratio. Gly-PLA showed the bimodal type DSC curve. The low $T_m$ peak of low molecular weight reduced but the high $T_m$ peak of high molecular weight increased as L-lactide/glycidol molar ratio increased.