• Title/Summary/Keyword: Reduced ring

Search Result 395, Processing Time 0.028 seconds

Synthesis of (${\pm}$)-cis-8-amino-l-2,3,4,4a,5,10b-hexahydrothiazolo[4,5-f]indeno [1,2-b][1,4]oxazine ((${\pm}$)-cis-8-Amino-2,3,4,4a,5,10b-hexahydrothiazolo[4,5-f]indeno [1,2-b][1,4]oxazine의 합성)

  • Ma, Eun-Sook
    • YAKHAK HOEJI
    • /
    • v.52 no.6
    • /
    • pp.488-493
    • /
    • 2008
  • 2-Aminothiazole ring as a bioisoster of catechol in dopamine has provided with good oral availability and lipophilic property. 2-Aminoindan, is a rigid form of dopamine, was evaluated as a dopamine D3 agonist with low neurotoxicity. Dopamine D3 agonist was evaluated as selective for the treatment of Parkinson's disease. In order to develop a novel dopamine D3 agonist, we tried to synthesize the aminothiazoloindenoxazine derivative that is a hybrid structure of aminoindenoxazine and thiazole ring. cis-2-Amino-1-indanol (2) was synthesized from 1,2-indandione-2-oxime by catalytic hydrogenation and it was treated with chloroacetyl chloride and NaH in benzene solution to give (${\pm}$)-cis-4,4a,5,9b-tetrahydroindeno[1,2-b][1,4]oxazin-3(2H)-one (6). Nitration of 6 by the mixed acid gave 8-nitro compound (7) and the carbonyl group of 7 was reduced with $LiAlH_4$ to afford compound (8). 8 was reduced to form (${\pm}$)-cis-8-amino-2,3,4,4a,5,9b-hexahydroindeno[1,2-b][1,4]oxazine (9) and finally it was cyclized with KSCN in glacial acetic acid to yield (${\pm}$)-cis-8-amino-2,3,4,4a,5,10b-hexahydrothiazolo[4,5-f]indeno[1,2-b][1,4]oxazine (10).

Positional Uncertainty Reduction of Overlapped Ultrasonic Sensor Ring for Efficient Mobile Robot Obstacle Detection (효율적인 이동로봇의 장애물 탐지를 위한 중첩 초음파 센서 링의 위치 불확실성 감소)

  • Kim, Sung-Bok;Lee, Sang-Hyup
    • Journal of the Institute of Convergence Signal Processing
    • /
    • v.10 no.3
    • /
    • pp.198-206
    • /
    • 2009
  • This paper presents the reduction of the positional uncertainty of an ultrasonic sensor ring with overlapped beam pattern for the efficient obstacle detection of a mobile robot. Basically, it is assumed that a relatively small number of inexpensive low directivity ultrasonic sensors are installed at regular spacings along the side of a circular mobile robot with their beams overlapped. First, for both single and double obstacles, we show that the positional uncertainty inherent to an ultrasonic sensor can be reduced using the overlapped beam pattern, and also quantify the relative improvement in positional uncertainty. Second, given measured distance data from one or two ultrasonic sensors, we devise the geometric method to determine the position of an obstacle with respect to the center of a mobile robot. Third, we examine and compare existing ultrasonic sensor models, including Gaussian distribution, parabolic distribution, uniform distribution, and impulse, and then build the sensor model of overlapped ultrasonic sensors, adequate for obstacle detection in terms of positional uncertainty and computational requirement. Finally, through experiments using our prototype ultrasonic sensor ring, the validity of overlapped beam pattern for reduced positional uncertainty and efficient obstacle detection is demonstrated.

  • PDF

Crystal Structure of Fully Dehydrated Partially Ag$^+$-Exchanged Zeolite 4A, $Ag_{7.6}Na_{4.4}$-A. Ag$^+$ Ions Prefer 6-Ring Sites. One Ag$^+$ Ion is Reduced

  • Kim, Yang;Han, Young-Wook;Seff, Karl
    • Bulletin of the Korean Chemical Society
    • /
    • v.7 no.3
    • /
    • pp.190-193
    • /
    • 1986
  • The structure of partially $Ag^+$-exchanged zeolite 4A, $Ag_{7.6}Na_{4.4}-A$, vacuum dehydrated at $370^{\circ}C$, has been determined by single-crystal x-ray diffraction techniques in the cubic space group, Pm3m (a = 12.311(1)${\AA}$) at $24(1)^{\circ}}C$. The structure was refined to the final error indices $R_1$ = $R_2$ (weighted) = 0.064 using 266 independent reflections for which $I_0$>$3{\sigma}(I_0)$. Three $Na^+$ ions occupy the 3 8-ring sites, and the remaining ions, 1.4 $Na^+$ and 6.6 $Ag^+$, fill the 8 6-ring sites; each $Ag^+$ ion is nearly in the [111] plane of its 3 O(3) ligands, and each $Na^+$ ion is 0.9${\AA}$ from its corresponding plane, on the large-cavity side. One reduced silver atom per unit cell was found inside the sodalite unit. It was presumably formed from the reduction of a $Ag^+$ ion by an oxide ion of a residual water molecule or of the zeolite framework. It may be present as a hexasilver cluster in 1/6 of the sodalite units, or, most attractively among several alternatives, as an isolated Ag atom coordinated to 4 Ag ions in each sodalite unit to give $(Ag_5)^{4+}$, symmetry 4mm.

Low Phase Noise VCO using Microstrip Square Open Loop Multiple Split Ring Resonator (마이크로스트립 사각 개방 루프 다중 SRR(Split Ring Resonator)를 이용한 저위상 잡음 전압 제어 발진기)

  • Choi, Jae-Won;Seo, Chul-Hun
    • Journal of the Institute of Electronics Engineers of Korea TC
    • /
    • v.44 no.11
    • /
    • pp.60-66
    • /
    • 2007
  • In this paper, a novel voltage-controlled oscillator (VCO) using the microstrip square open loop multiple split ring resonator (OLMSRR) is presented for reducing the phase noise property. The square-shaped multiple split ring resonator (MSRR) having the form of the microstrip square open loop is investigated to realize this property. Compared with the microstrip square open loop resonator and the microstrip square open loop split ring resonator (OLSRR) as well as the conventional microstrip line resonator, the microstrip square OLMSRR has the larger coupling coefficient value, which makes a higher Q value, and has reduced the phase noise of VCO. The VCO with 1.7V power suppIy has the phase noise of $-124.5\;{\sim}\;-122.0\;dBc/Hz$ @ 100 kHz in the tuning range, $5.746\;{\sim}\;5.84\;GHz$. The figure of merit (FOM) of this VCO is $-203.96\;{\sim}\;-201.6\;dBc/Hz$ @ 100 kHz in the same tuning range. Compared with VCO using the conventional microstrip line resonator, VCO using the microstrip square open loop resonator and VCO using microstrip square OLSRR, the phase noise property of VCO using the proposed resonator has been improved in 25.66 dB, 8.34 dB, and 4.5 dB, respectively.

Properties and Prediction Model for Ultra High Performance Fiber Reinforced Concrete (UHPFRC): (II) Evaluation of Restrained Shrinkage Characteristics and Prediction of Degree of Restraint (초고성능 섬유보강 콘크리트(UHPFRC)의 재료 특성 및 예측모델: (II) 구속 수축 특성 평가 및 구속도 예측)

  • Yoo, Doo-Yeol;Park, Jung-Jun;Kim, Sung-Wook;Yoon, Young-Soo
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.32 no.5A
    • /
    • pp.317-325
    • /
    • 2012
  • In this study, to evaluate the shrinkage behavior of ultra high performance fiber reinforced concrete (UHPFRC) under restrained condition, restrained shrinkage test was performed according to ring-test mostly used at home and abroad. Ring-test was performed with the various thicknesses and radii of inner steel ring to give different degree of restraint. Free shrinkage and tensile tests were carried out simultaneously to estimate the degree of restraint, stress relaxation, and shrinkage cracking potential. Test results indicated that the average steel strain and residual tensile stress were reduced as the thicker inner steel ring was used, whereas degree of restraint was increased. The steel strain, residual tensile stress and degree of restraint were hardly affected by the size of radius of inner ring. In the case of all ring specimens, shrinkage crack did not occur because the residual tensile stress was lower than the tensile strength. About 39~65% of the elastic shrinkage stress was relaxed by the sustained interface pressure, and the maximum relaxed stress was increased as the thicker inner ring was applied. Finally, the degree of restraint with age was predicted by performing non-linear regression analysis, and it was in good agreement with the test results.

Effect of Board Thickness and Ring Angle on Press - drying for Heartwood and Sapwood of Quercus acutissima C. (상수리나무 심재(心材)와 변재판재(邊材板材)의 두께와 연륜각도(年輪角度)가 열판건조(熱板乾燥)에 미치는 영향(影響))

  • Lee, Nam-Ho;Jung, Hee-Suk
    • Journal of the Korean Wood Science and Technology
    • /
    • v.15 no.2
    • /
    • pp.67-78
    • /
    • 1987
  • This study was designed to investigate the effect of board thickness and ring angle on the characteristics including internal check. ring failure, surface check, end check, collapse, thickness shrinkage and width shrinkage of press-drying. The exprimental materials of 6mm-. 9mm- and 12mm-thick board were taken from heartwood and sapwood of oak (Quercus acutissima Carr.) respectively. And boards were numbered according to position in the log(No. 1 to No. 4 for heartwood :md No. 9 for sapwood). Press-drying was at $145^{\circ}C$ platen temperature and 3.5kg/$Cm^2$ platen pressure. The results of this study were summarized as follows. 1. Drying rates for sapwood materials were greater than those for heartwood materials. And drying rates for thinner materials were greater than those for thicker materials. 2. The thinner boards were. the severer surface checking developed in the heartwood materials, and surface checking for heartwood materials had no tendency in board position for the same thickness. Sapwood materials were completely free from surface checking. 3. End checking for heartwood materials had no tendency in board position. The greater deviation of ring angle from perfectly edge-grained was, the severer and checking developed in the sapwood materials. But end checking did not occur in 6mm-thick sapwood materials. 4. The greater deviation of ring angle from perfectly edge-grained was, the severer end checking developed for heartwood and sapwood materials. As board thickness increased, maternal checking developed more severely for heartwood and sapweed materials. 5. For heartwood materials, ring failure, reduced with increasing deviation of ring angle from perfectly edge-grained except 12mm-thick material and showed no significant difference attributable to board thickness. Sapwood materials were completely free from ring failure. 6. For heartwood and sapwood materials, collapse was slight and showed no significant differences attributable to both board thickness and board position. 7. As deviation of ring angle from perfectly edge-grained increased, shrinkage of board thickness decreased for heartwood and sapwood materials. 8. Shrinkage of board width showed no significant differences attributable to both board thickness and board position for heartwood and sapweed materials.

  • PDF

Endothelium-Dependent Vasorelaxation Effects of Rubus Coreanus extract on Rabbit Carotid Artery (복분자(覆盆子)의 내피세포의존성 혈관이완효과)

  • Chin, Jun Ho;Park, Sun Young
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.27 no.4
    • /
    • pp.437-445
    • /
    • 2013
  • This study was investigated to evaluate the vasorelaxant effect of Rubus coreanus(RC) extract on contracted rabbit carotid artery and its mechanism. To study the effect of RC extract on contracted rabbit carotid arterial strips, arterial strips with intact or damaged endothelium were used for experiment using organ bath. The pre-contracted arterial strips with norepinephrine(NE) or potassium chloride(KCl) was treated with various concentrations of an extract of RC(0.01, 0.03, 0.1, 0.3 and 1.0 $mg/m{\ell}$). To determine the mechanisms of RC-induced vasorelaxant, RC extract was infused into contracted arterial rings which had been pretreated by indomethacin(IM), tetraethylammonium chloride(TEA), $N{\omega}$-nitro-L-arginine (L-NNA), methylene blue(MB). And calcium chloride(Ca) 1 mM was infused into precontracted arterial ring induced by NE or KCl after treatment of RC extract in $Ca^{2+}$-free krebs solution. Cytotoxic activity of RC extract on human umbilical vein endothelial cell(HUVEC) was measured by MTT assay, and nitric oxide(NO) prodution was measured by Griess reagent. RC extract revealed significant relaxation on NE-induced arterial contraction, but didn't relax on KCl-induced arterial contraction. RC extract also had an effective relaxation to the intact endothelium arterial ring, but not the damaged endothelium arterial ring. Treatment of IM, TEA, L-NNA, MB reduced the relaxation of RC extract. Pretreatment of RC extract inhibited the contraction by influx of extracellular $Ca^{2+}$ in contracted arterial ring induced by NE, but it didn't work the contraction by influx of extracellular $Ca^{2+}$ in contracted arterial ring induced by KCl in $Ca^{2+}$-free krebs solution. RC extract increased nitric oxide production on HUVEC. This study indicated that the relaxation effect of RC extract on contracted rabbit carotid artery is related with NO-cGMP pathway, EDHF, prostacyclin.

Ring Hybrid Coupler with Compact Size and Wide Bandwidth (넓은 대역폭을 가지는 소형 링 하이브리드)

  • Kim, Ui-Jung;Kim, Seung-Hwan;Kim, Ell-Kou;Lee, Young-Soon;Kim, Young;Yoon, Young-Chul
    • Journal of Advanced Navigation Technology
    • /
    • v.13 no.2
    • /
    • pp.194-200
    • /
    • 2009
  • This paper introduces a ring hybrid coupler using shunt capacitors, high impedance lines and CRLH-TLs (Composite Right/Left-Handed Transmission Lines) with size reduction and bandwidth enhancement. The reduced method of line length uses to combine a short length high impedance line and shunt capacitors. Also, there is combined CRLH meta-material so as to obtain wide bandwidth of transmission line using nonlinear phase characteristic of CRLH-TL that consists of series capacitors and shunt inductors. The implemented ring hybrid coupler shows a novel design with compact size that is smaller than 10% and bandwidth is larger than 60% of conventional ring hybrid coupler.

  • PDF

Gesture Recognition Using Zernike Moments Masked By Duel Ring (이중 링 마스크 저니키 모멘트를 이용한 손동작 인식)

  • Park, Jung-Su;Kim, Tae-Yong
    • Journal of the Institute of Electronics and Information Engineers
    • /
    • v.50 no.10
    • /
    • pp.171-180
    • /
    • 2013
  • Generally, when we apply zernike moments value for matching, we can use those moments value obtained from projecting image information under circumscribed circle to zernike basis function. However, the problem is that the power of discrimination can be reduced because hand images include lots of overlapped information due to its special characteristic. On the other hand, when distinguishing hand poses, information in specific area of image information except for overlapped information can increase the power of discrimination. In this paper, in order to solve problems like those, we design R3 ring mask by combining image obtained from R2 ring mask, which can weight information of the power of discrimination and image obtained from R1 ring mask, which eliminate the overlapped information. The moments which are obtained by R3 ring mask decrease operational time by reducing dimension through principle component analysis. In order to confirm the superiority of the suggested method, we conducted some experiments by comparing our method to other method using seven different hand poses.