• Title/Summary/Keyword: Reduced mechanism

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Anti-adipogenic Effect of Kaempferol, a Component of Polygonati Rhizoma (황정(黃精)과 Kaempferol의 지방세포 분화 억제 효과)

  • Jang, Jae-Sik;Jeong, Ji-Cheon
    • The Journal of Korean Medicine
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    • v.31 no.2
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    • pp.158-166
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    • 2010
  • Objective: It has been reported that Polygonati rhizoma (Pr) has anti-hyperglycemia, anti-triglycemia, anti-diabetic, and anti-tumor activity. Total extract of Pr was tested to identify anti-adipogenic activity in 3T3-L1 differentiation and molecular mechanism of Pr in 3T3-L1 differentiation. Methods: Differentiation of 3T3-L1 pre-adipocyte was induced in the presence of Pr extract and kaempferol. The level of lipid accumulation was measured by Oil Red O staining. The expression of genes associated with adipocyte differentiation was measured by RT-PCR. Results: Extract of Pr and its component kaempferol reduced lipid accumulation in 3T3-L1 during adipogenesis and also reduced mRNA levels of genes associated with adipogenesis, such as adipsin, aP2, LPL, SERBP-1c and $PPAR{\gamma}$. Conclusions: In this study, we showed that the molecular mechanism of Pr and kaempferol activity is related to regulation of $PPAR{\gamma}$ expression and activation.

Adaptive Conversion of Web Content for Mobile Terminals (이동단말을 위한 적응적 웹 문서 변환)

  • Kang, Sueng-Chun;Chung, Kwang-Sue
    • Journal of KIISE:Computing Practices and Letters
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    • v.6 no.6
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    • pp.635-642
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    • 2000
  • In this paper, we proposed an efficient document conversion mechanism to provide a adaptive web document to mobile terminals. We also proposed a RHTML(Reduced HTML) to archive the adaptive tag reduction. Markup error correction process in the proposed adaptive document conversion mechanism converts a HTML(HyperText Markup Language) document into a XML(Extensible Markup Language) application document. This. process makes web document easy to handle with a DOM (Document Object Mode)) as the tree model and removes the hardware overhead in mobile terminals. Also, tag reduction process provides the adaptive web document with three DTD(Document Type Definition)s in the RHTML.

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Lattice Oxygen Activation in NiFe (Oxy)hydroxide using Se (셀레늄을 활용한 니켈철 (옥시)수산화물의 격자 산소 활성화)

  • Jo, Seunghwan;Sohn, Jung Inn
    • Korean Journal of Materials Research
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    • v.32 no.8
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    • pp.339-344
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    • 2022
  • The lattice oxygen mechanism (LOM) is considered one of the promising approaches to overcome the sluggish oxygen evolution reaction (OER), bypassing -OOH* coordination with a high energetic barrier. Activated lattice oxygen can participate in the OER as a reactant and enables O*-O* coupling for direct O2 formation. However, such reaction kinetics inevitably include the generation of oxygen vacancies, which leads to structural degradation, and eventually shortens the lifetime of catalysts. Here, we demonstrate that Se incorporation significantly enhances OER performance and the stability of NiFe (oxy)hydroxide (NiFe) which follows the LOM pathway. In Se introduced NiFe (NiFeSe), Se forms not only metal-Se bonding but also Se-oxygen bonding by replacing oxygen sites and metal sites, respectively. As a result, transition metals show reduced valence states while oxygen shows less reduced valence states (O-/O22-) which is a clear evidence of lattice oxygen activation. By virtue of its electronic structure modulation, NiFeSe shows enhanced OER activity and long-term stability with robust active lattice oxygen compared to NiFe.

Development and Performance Study of a Zero-Copy File Transfer Mechanism for Ink-based PC Cluster Systems (VIA 기반 PC 클러스터 시스템을 위한 무복사 파일 전송 메커니즘의 개발 및 성능분석)

  • Park Sejin;Chung Sang-Hwa;Choi Bong-Sik;Kim Sang-Moon
    • Journal of KIISE:Computer Systems and Theory
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    • v.32 no.11_12
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    • pp.557-565
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    • 2005
  • This paper presents the development and implementation of a zero-copy file transfer mechanism that improves the efficiency of file transfers for PC cluster systems using hardware-based VIA(Virtual Interface Architecture) network adapters. VIA is one of the representative user-level communication interfaces, but because there is no library for file transfer, one copy occurs between kernel buffer and user boilers. Our mechanism presents a file transfer primitive that does not require the file system to be modified and allows the NIC to transfer data from the kernel buffer to the remote node directly without copying. To do this, we have developed a hardware-based VIA network adapter, which supports the PCI 64bit/66MHz bus and Gigabit Ethernet, as a NIC, and implemented a zero-copy file transfer mechanism. The experimental results show that the overhead of data coy and context switching in the sender is greatly reduced and the CPU utilization of the sender is reduced to $30\%\~40\%$ of the VIA send/receive mechanism. We demonstrate the performance of the zero-copy file transfer mechanism experimentally. and compare the results with those from existing file transfer mechanisms.

Effective IPv6 Address Allocation Mechanism in All IP Wireless Networks (차세대 이동통신망에서 효율전인 IPv6 주소할당 방안)

  • 정현철;민상원
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.2B
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    • pp.240-249
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    • 2004
  • For the effective IP-based service implementation in the wireless network environment, involvement of IP-related technologies in wireless networks is inevitable and globally unique IPv6 address allocation to the mobile node has become an important issue. In the 3GPP's address allocation mechanism, IPv6 address allocation procedure is performed by the GGSN, which is normally located far from the mobile nodes. This causes IPv6 address allocation time delay and traffics to be longer and increased in the core network, respectively. In this paper, we propose a new IPv6 address allocation mechanism that is performed by Node B located in RAN. The proposed IPv6 address allocation mechanism can provide IPv6 addresses to mobile nodes within a more reduced time than existing 3GPP's IPv6 address allocation mechanism, and co-operates with existing mechanism as an overlay model to improve reliability of wireless networks. And, for implementation of the proposed address allocation mechanism, it needs not to change the structure of current wireless networks except for the some functional addendum of Node B.

A New Dynamic Paging Mechanism for HMIPv6 Networks (HMIPv6환경에서 새로운 동적 페이징 기법)

  • Jeong, Yu-Jin;Choe, Jong-Won
    • Journal of KIISE:Information Networking
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    • v.32 no.6
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    • pp.687-695
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    • 2005
  • With increasing demand of using mobile Internet, HMIPv6 is proposed by IETF to reduce location management traffics due to micro mobility and to provide IP-based movement. A paging mechanism combined with HMIPv6 can reduce the signaling traffics of a mobile node. We propose a dynamic paging mechanism in HMIPv6 which decides an optimal paging area for each mobile node by considering its characteristics. Total costs of a static paging mechanism and a dynamic paging mechanism are analyzed by mathematical formulas. As a result, we proved that the dynamic paging mechanism reduced total signal traffic costs more than a static paging mechanism.

Study on Peripheral Mechanism and Opioid Receptors Implicated in Electroacupunture-induced Inbibition of Chronic Pain (만성통증을 억제하는 전침효과의 말초성 기전과 아편양물질수용기에 관한 연구)

  • 신홍기;이서은;박동석
    • The Journal of Korean Medicine
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    • v.24 no.3
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    • pp.108-117
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    • 2003
  • Objective : The central opioid mechanism of acupuncture analgesia has been fairly well documented in acute behavioral experiments, but little electrophysiological study has been performed on the peripheral mechanism and subtypes of opioid receptors responsible for acupuncture-induced antinociception in chronic animal models. In the present electrophysiological experiment, we studied the peripheral mechanism and opioid receptor subtypes which Were implicated in electroacupuncture-induced antinociception in the rat with chronic inflammatory and neurogenic pain. Methods : In the rat with complete Freund's adjuvant-induced inflammation and spinal nerve injury, dorsal horn cell responses to afferent C fiber stimulation were recorded before and after electroacupuncture (EA) stimulation applied to the contralateral Zusanli point for 30 minutes. Also studied Were the effects of specific opioid receptor antagonists and naloxone methiodide, which can not cross the blood-brain barrier, on EA-induced inhibitory action. Results : EA-induced inhibitory action was significantly attenuated by naloxone methiodide, suggesting that EA-induced inhibition was mediated through peripheral mechanism. Pretreatment, but not posttreatment of naltrexone and spinal application significantly blocked EA-induced inhibitory actions. In inflammatory and neurogenic pain models, ${\mu}-$ and ${\delta}-opioid$ receptor antagonists (${\beta}-funaltrexamine$ & naltrindole) significantly reduced EA-induced inhibitory action, but ${\kappa}-opioid$ receptor antagonist had weak inhibitory effect on EA-induced antinociception. Conclusion : These results suggest that 2Hz EA-stimulation induced antinoeiceptive action is mediated through peripheral as well as central mechanism, and mainly through ${\mu}-$ and ${\delta}-opioid$ receptors.

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Packet Scheduling Mechanism to Improve TCP Throughput Using Link State Information in Wireless Networks (무선 네트워크에서 링크 상태 정보를 이용하는 TCP 효율 향상을 위한 패킷 스케줄링 매커니즘)

  • Kim Seong-Cheol;Lee Jin-Young
    • Journal of Korea Multimedia Society
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    • v.7 no.10
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    • pp.1443-1451
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    • 2004
  • In this paper we propose a new packet scheduling mechanism to improve TCP throughput and fairness with estimated link state information in wireless networks, in which mobile hosts are receivers. Since a priori estimated link state information is used in this proposed mechanism, the entire packet transmission time can be reduced. In other words, packets scheduling procedure is performed before packets are transmitted using estimated link state. The proposed mechanism also has an temporary FIFO queue to store packets which are on the head of queue and can not be transmitted due to bad link state. Using this temporary FIFO queue, HOL(Head of Line) problem of FIFO queue can be resolved.

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Virtual Arrival Mechanism for IEEE 802.15.4 beacon enabled networks (비콘을 사용하는 IEEE 802.15.4 네트워크를 위한 가상 도착 메커니즘)

  • Ha, Jae-Yeol;Lee, Jong-Wook;Kwon, Wook-Hyun;Kim, Jung-Joon;Kim, Yong-Ho;Shin, Young-Hee
    • Journal of The Institute of Information and Telecommunication Facilities Engineering
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    • v.4 no.2
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    • pp.45-51
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    • 2005
  • For power constrained applications, IEEE 802.15.4 networks may be operated in beacon enabled mode with inactive period. h this paper, we propose the Virtual Arrival Mechanism (VAM) to avoid the congestion at the beginning of each contention access period (CAP). Virtual Arrival Mechanism (VAM) is a kind of traffic shaping that spread the traffics congested at the beginning of CAP into the whole CAP. By using VAM, collisions and energy consumption can be reduced. Finally, we evaluate the performance enhancement of VAM using NS-2 simulator.

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The Effect of Residence Time and Heat Loss on NOx Formation Characteristics in the Downstream Region of CH4/Air Premixed Flame (CH4/Air 예혼합화염의 하류영역에서 체류시간 및 열손실에 의한 NOx의 생성특성)

  • Hwang, Cheol-Hong;Hyun, Sung-Ho;Tak, Young-Jo;Lee, Chang-Eon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.31 no.1 s.256
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    • pp.99-108
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    • 2007
  • In this study, the NOx formation characteristics of one-dimensional $CH_4$/Air premixed flame using detailed-kinetic chemistry are examined numerically. The combustor length and the amount of heat loss are varied to investigate the effect of residence time and heat loss on the NOx formation in a post-flame region. In the flame region, NO is mainly produced by the Prompt NO mechanism including $N_2$O-intermediate NO mechanism over all equivalence ratios. However, thermal NO mechanism is more important than Prompt NO mechanism in the post-flame region. In the case of adiabatic condition, the increase of combustor length causes the remarkable increase of NO emission at the exit due to the increase of residence time. On the other hand, NO reaches the equilibrium state in the vicinity of flame region, considering radiation and conduction heat losses. Furthermore the NO, in the case of $\phi$=1.2, is gradually reduced in the downstream region as the heat loss is increased. From these results, it can be concluded that the controls of residence time and heat loss in a combustor should be recognized as an important NOx reduction technology.