• Title/Summary/Keyword: Rectal volume

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Study of Efficient Cooling Part for Cooling Clothes Development (냉각복 개발을 위한 효율적 냉각부위 규명에 관한 연구)

  • 최정화;황경숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.26 no.6
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    • pp.771-778
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    • 2002
  • Cooling clothes especially cooling vest are being considered for as an efficient way to reduce heat strain under hot environment. But wearing ice gel or ice-based cooling vest caused discomfort to subjects due to the weight of vest. Therefore, this study was executed to find efficient cooling parts and to reduce vest weight by cooling only these parts. Two male subjects were exposed to heat(40$^{\circ}C$, 30%RH) with A type(breast+back+abdomen+waist), B type(breast+back+waist), C type(breast+back+abdomen) and D type(breast+back) cooling vest that distinguished with cooling part. The results were as follows; When subjects were C type and D type vest, sweat volume was less and skin temperature was low. Heart rate and rectal temperature were low in B type and D type. These results suggest that excessive cooling of breast and abdomen may exert a bad influence to health and cooling of back is desirable.

Effectiveness of Cooling Vest in Hot Environment (더운환경에서의 냉각조끼의 착용효과에 관한 연구)

  • 최정화;황경숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.25 no.1
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    • pp.83-90
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    • 2001
  • Cooling garments are being considered for reducing heat strain in hot environment. We evaluated the effectiveness of ice gel-based cooling vest in hot environment both resting and exercising. Four male subjects were exposed to heat(4$0^{\circ}C$, 50%RH) with vest or without it. The results were as follows; In case of the trial wearing ice gel-based cooling vest, total body weight loss, and local sweat volume were less than those without it. Mean skin temperature, rectal temperature, pulse, energy expenditure, temperature of inside clothes, and humidity of inside also were lower than those without cooling vest. By subjective thermal sensation, subjective humidity sensation, and thermal comfort sensation, it was proved that non-wearing vest decreased comfort than wearing that. These results suggested that wearing ice gel-based cooling vest reduced human heat strain in hot environment both resting and exercising.

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Bladder And Rectum Dose Define 3D Treatment Planning for Cervix Cancer Brachtherapy Comparison of Dose-Volume Histograms for Organ Contour and Organ Wall Contour (자궁경부암의 고선량률 근접치료시 장기묘사 방법에 따른 직장과 방광의 선량비교 분석)

  • Kim, Jong-Won;Kim, Dae-Hyun;Choi, Joon-Yong;Won, Yeong-Jin
    • Journal of radiological science and technology
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    • v.35 no.4
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    • pp.327-333
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    • 2012
  • Purpose: To analyze the correlation between dose volume histograms(DVH) based on organ outer wall contour and organ wall delineation for bladder and rectum, and to compare the doses to these organs with the absorbed doses at the bladder and rectum. Material and methods: Individual CT based brachytherapy treatment planning was performed in 13 patients with cervical cancer as part of a prospective comparative trial. The external contours and the organ walls were delineated for the bladder and rectum in order to compute the corresponding dose volume histograms. The minimum dose in 0.1 $cm^3$, 1 $cm^3$, 2 $cm^3$, 5 $cm^3$, 10 $cm^3$ volumes receiving the highest dose were compared with the absorbed dose at the rectum and bladder reference point. Results: The bladder and rectal doses derived from organ outer wall contour and computed for volumes of 2 $cm^3$, provided a good estimate for the doses computed for the organ wall contour only. This correspondence was no longer true when large volumes were considered. Conclusion: For clinical applications, when volumes smaller than 5 $cm^2$ are considered, the dose-volume histograms computed from external organ contours for the bladder and rectum can be used instead of dose -volume histograms computed for the organ walls only. External organ contours are indeed easier to obtain. The dose at the ICRU rectum reference point provides a good estimate of the rectal dose computed for volumes smaller than 2 $cm^2$ only for a midline position of the rectum. The ICRU bladder reference point provides a good estimate of the dose computed for the bladder wall only in cases of appropriate balloon position.

Comparison of CT based-CTV plan and CT based-ICRU38 plan in brachytherapy planning of uterine cervix cancer (자궁경부암 강내조사 시 CT를 이용한 CTV에 근거한 치료계획과 ICRU 38에 근거할 치료계획의 비교)

  • Shim JinSup;Jo JungKun;Si ChangKeun;Lee KiHo;Lee DuHyun;Choi KyeSuk
    • The Journal of Korean Society for Radiation Therapy
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    • v.16 no.2
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    • pp.9-17
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    • 2004
  • Purpose : Although Improve of CT, MRI Radio-diagnosis and Radiation Therapy Planing, but we still use ICRU38 Planning system(2D film-based) broadly. 3-Dimensional ICR plan(CT image based) is not only offer tumor and normal tissue dose but also support DVH information. On this study, we plan irradiation-goal dose on CTV(CTV plan) and irradiation-goal dose on ICRU 38 point(ICRU38 plan) by use CT image. And compare with tumor-dose, rectal-dose, bladder-dose on both planning, and analysis DVH Method and Material : Sample 11 patients who treated by Ir-192 HDR. After 40Gy external radiation therapy, ICR plan established. All the patients carry out CT-image scanned by CT-simulator. And we use PLATO(Nucletron) v.14.2 planing system. We draw CTV, rectum, bladder on the CT image. And establish plan irradiation-$100\%$ dose on CTV(CTV plan) and irradiation-$100\%$ dose on A-point(ICRU38 plan) Result : CTV volume($average{\pm}SD$) is $21.8{\pm}26.6cm^3$, rectum volume($average{\pm}SD$) is $60.9{\pm}25.0cm^3$, bladder volume($average{\pm}SD$) is $116.1{\pm}40.1cm^3$ sampled 11 patients. The volume including $100\%$ dose is $126.7{\pm}18.9cm^3$ on ICRU plan and $98.2{\pm}74.5cm^3$ on CTV plan. On ICRU planning, the other one's $22.0cm^3$ CTV volume who residual tumor size excess 4cm is not including $100\%$ isodose. 8 patient's $12.9{\pm}5.9cm^3$ tumor volume who residual tumor size belows 4cm irradiated $100\%$ dose. Bladder dose(recommended by ICRU 38) is $90.1{\pm}21.3\%$ on ICRU plan, $68.7{\pm}26.6\%$ on CTV plan, and rectal dose is $86.4{\pm}18.3\%,\;76.9{\pm}15.6\%$. Bladder and Rectum maximum dose is $137.2{\pm}50.1\%,\;101.1{\pm}41.8\%$ on ICRU plan, $107.6{\pm}47.9\%,\;86.9{\pm}30.8\%$ on CTV plan. Therefore CTV plan more less normal issue-irradiated dose than ICRU plan. But one patient case who residual tumor size excess 4cm, Normal tissue dose more higher than critical dose remarkably on CTV plan. $80\%$over-Irradiated rectal dose(V80rec) is $1.8{\pm}2.4cm^3$ on ICRU plan, $0.7{\pm}1.0cm^3$ on CTV plan. $80\%$over-Irradiated bladder dose(V80bla) is $12.2{\pm}8.9cm^3$ on ICRU plan, $3.5{\pm}4.1cm^3$ on CTV plan. Likewise, CTV plan more less irradiated normal tissue than ICRU38 plan. Conclusion : Although, prove effect and stability about previous ICRU plan, if we use CTV plan by CT image, we will reduce normal tissue dose and irradiated goal-dose at residual tumor on small residual tumor case. But bigger residual tumor case, we need more research about effective 3D-planning.

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Comparison of Doses According to Change of Bladder Volume in Treatment of Prostate Cancer (전립선암 치료 시 방광의 용적 변화에 따른 선량의 비교 평가)

  • Kwon, Kyung-Tae;Min, Jung-Whan
    • Journal of radiological science and technology
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    • v.40 no.3
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    • pp.415-421
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    • 2017
  • In the case of radiation therapy for prostate cancer, a balloon infused with a certain amount of air through the anus is used to reduce rectal dose. Because of the reason, radiation therapy for prostate cancer has acquired CBCT for daily image induction. In order to maintain the anatomical structure most similar to the first CT taken before treatment, it is pretreated, but it can not be said to be perfectly consistent. In two actual treatment regimens, the volume of the bladder was measured as 45.82 cc and 63.43 cc, and the equivalent diameter was 4.4 cm and 4.9 cm. As a result of this study, the mean volume of the bladder was estimated to be 56.2 cc, 105.6 cc by 20 CBCT. The mean dose of CBCT was 1.74% and the mean Bladder mean dose was 96.67%. In case B, PTV mean dose was 4.31%, Bladder mean Dose was estimated to be 97.35%. The changes in the volume of the bladder resulted in changes in the dose of PTV and bladder. The correlation coefficient of bladder dose according to the change of bladder volume showed linearity of mean dose $R^2=-0.94$. The correlation coefficient of the PTV dose according to the volume change of the bladder showed linearity of mean dose $R^2=0.04$. It was found that the dose change of PTV was larger than that of bladder according to the change of bladder volume.

Comparative Evaluation of Two-dimensional Radiography and Three Dimensional Computed Tomography Based Dose-volume Parameters for High-dose-rate Intracavitary Brachytherapy of Cervical Cancer: A Prospective Study

  • Madan, Renu;Pathy, Sushmita;Subramani, Vellaiyan;Sharma, Seema;Mohanti, Bidhu Kalyan;Chander, Subhash;Thulkar, Sanjay;Kumar, Lalit;Dadhwal, Vatsla
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4717-4721
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    • 2014
  • Background: Dosimetric comparison of two dimensional (2D) radiography and three-dimensional computed tomography (3D-CT) based dose distributions with high-dose-rate (HDR) intracavitry radiotherapy (ICRT) for carcinoma cervix, in terms of target coverage and doses to bladder and rectum. Materials and Methods: Sixty four sessions of HDR ICRT were performed in 22 patients. External beam radiotherapy to pelvis at a dose of 50 Gray in 27 fractions followed by HDR ICRT, 21 Grays to point A in 3 sessions, one week apart was planned. All patients underwent 2D-orthogonal and 3D-CT simulation for each session. Treatment plans were generated using 2D-orthogonal images and dose prescription was made at point A. 3D plans were generated using 3D-CT images after delineating target volume and organs at risk. Comparative evaluation of 2D and 3D treatment planning was made for each session in terms of target coverage (dose received by 90%, 95% and 100% of the target volume: D90, D95 and D100 respectively) and doses to bladder and rectum: ICRU-38 bladder and rectum point dose in 2D planning and dose to 0.1cc, 1cc, 2cc, 5cc, and 10cc of bladder and rectum in 3D planning. Results: Mean doses received by 100% and 90% of the target volume were $4.24{\pm}0.63$ and $4.9{\pm}0.56$ Gy respectively. Doses received by 0.1cc, 1cc and 2cc volume of bladder were $2.88{\pm}0.72$, $2.5{\pm}0.65$ and $2.2{\pm}0.57$ times more than the ICRU bladder reference point. Similarly, doses received by 0.1cc, 1cc and 2cc of rectum were $1.80{\pm}0.5$, $1.48{\pm}0.41$ and $1.35{\pm}0.37$ times higher than ICRU rectal reference point. Conclusions: Dosimetric comparative evaluation of 2D and 3D CT based treatment planning for the same brachytherapy session demonstrates underestimation of OAR doses and overestimation of target coverage in 2D treatment planning.

The Study for standardized Method of the Retention-Enema; For a Method of Experimental Study (보류관장의 표준화된 방법을 위한 고찰을 통한 제언; 실험연구방법에 대하여)

  • Song, Eun-Young;Lee, Eui-Ju;Yoo, Jung-Hee;Lee, Jun-Hee;Koh, Byung-Hee;Bu, Yong-Min;Park, Jae-Woo;Kim, Hyo-Jin;Chai, Kwang-Min
    • The Journal of Korean Medicine
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    • v.35 no.1
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    • pp.1-9
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    • 2014
  • Objectives: This study was to propose a standardized method of retention enema by extracting elements associated with published experimental methods of retention enema. Methods: 1) Literature search (1) Data sources: Retrieval was made, using 'Enema' or 'Retention Enema' as search words in Medline, Cochrane library, KISS, RISS, and KDSL DB. (2) Study selection: Two authors excluded irrelevant papers and chose qualified abstracts from the rest of the papers. The chosen studies were reviewed fully by the authors so that they could screen the significant papers based on the exclusion criteria. (3) Data extraction: Data on the total number of subjects, the target disease, the animal species, the type, quality, length, and diameter of catheter, the insertion length of catheter, the sample, the sample volume, the process of retention enema and the number of retention enemas performed were extracted from the selected studies. 2) Performing preliminary experiments about the elements associated with experimental methods of retention enema. Results & Conclusions: The standardized experimental method is as follows: animal: 280-320g SD rat 1) inserting a rectal tube of 8 Fr that measures 8 cm into the animal's anus, 2) injecting herbal medicines at the volume of 6ml and 3) holding them for 10 minutes.

Intensity-modulated Radiotherapy Combined with Endocrine Therapy for Intermediate and Advanced Prostate Cancer: Long-term Outcome of Chinese Patients

  • Luo, Hua-Chun;Cheng, Hui-Hua;Lin, Gui-Shan;Fu, Zhi-Chao;Li, Dong-Shi
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4711-4715
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    • 2013
  • Aim: The aim of this study was to evaluate acute adverse events and efficacy of three-dimensional intensitymodulated radiotherapy (IMRT) combined with endocrine therapy for intermediate and advanced prostate cancer. Methods: Sixty-seven patients were treated with three-dimensional IMRT combined with maximum androgen blockade. The correlation between radiation-induced rectal injury and clinical factors was further analyzed. Results: After treatment, 21 patients had complete remission (CR), 37 had partial remission (PR), and nine had stable disease (SD), with an overall response rate of 86.5%. The follow-up period ranged from 12.5 to 99.6 months. Thirty-nine patients had a follow-up time of ${\geq}$ five years. In this group, three-year and five-year overall survival rates were 89% and 89.5%, respectively; three-year and five-year progression-free survival rates were 72% and 63%. In univariate analyses, gross tumor volume was found to be prognostic for survival ($X^2$ = 5.70, P = 0.037). Rates of leucopenia and anemia were 91.1% and 89.5%, respectively. Two patients developed acute liver injury, and a majority of patients developed acute radiation proctitis and cystitis, mainly grade 1/2. Tumor volume before treatment was the only prognostic factor influencing the severity of acute radiation proctitis (P < 0.05). Conclusions: IMRT combined with endocrine therapy demonstrated promising efficacy and was well tolerated in patients with intermediate and advanced prostate cancer.

A Comparison between Three Dimensional Radiation Therapy and Intensity Modulated Radiation Therapy on Prostate Cancer (전립샘암의 방사선 치료 시 입체조형치료법와 세기조절방사선 치료법의 비교)

  • Kim, YoungJae;Lee, JaeSub;Hong, Seongill;Ko, HyeJin
    • Journal of the Korean Society of Radiology
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    • v.7 no.6
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    • pp.409-414
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    • 2013
  • In this study, we evaluated to the superiority of treatment techniques on prostate cancer, apply to each other treatment techniques-3D conformal therapy versus IMRT-using dose distribution and dose coverages. Obtained 10 patients CT simulation, divided tumor volume and critical organs. Prescription dose was 80 Gy on tumor volume and Each of plans was set by two different plans. As a result, Dose coverage was superior to IMRT. The IMRT's tumor absorbed dose(100.2%) was close to prescription doses. Normal tissue(bladder, rectal, bowel Lt Rt fumoral head) absorbed dose rate was superior. In other words, the radiation therapy of prostate cancer with intensity modulated radiation therapy was better than conformal radiation therapy on dose.

EFFECTS OF HEAT EXPOSURE ON WATER METABOLISM AND PASSAGE IN SHEEP

  • Katoh, K.;Buranakarl, C.;Matsunaga, N.;Lee, S.R.;Sugawara, T.;Sasaki, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.2 no.2
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    • pp.91-97
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    • 1989
  • The present experiment was carried out to investigate the effects of heat exposure on water metabolism and the passage of indigestible particles in sheep. Water intake, respiratory rate, rectal temperature and pH of ruminal fluid and urine were significantly higher (P<0.05) in the hot environment ($32\;^{\circ}C$) than in the control environment ($20\;^{\circ}C$). Urine osmolality and blood volume were increased, while glomerular filtration rate was decreased, in the hot environment. The liquid flow rate from reticulo-rumen and the excretion of indigestible particles of specific gravity 0.99 (but not 1.27 or 1.38) were increased in the hot environment. From these findings, it is suggested that an increased water intake evoked by heat exposure might affect the flow rate of digesta in sheep.