• Journal of Ecology and Environment
• /
• v.34 no.3
• /
• pp.251-257
• /
• 2011

The purpose of this study was to investigate the acclimation responses of Tamarix chinensis to cold stress. We evaluated the acclimation responses by measuring biomass, daily elongation rate, chlorophyll content, and total soluble carbohydrate content. The plant samples comprised leaves from seedlings of 2 different ages (8 and 12 weeks); the leaves were collected 0, 2, and 4 weeks after cold treatment. We found that the cold-treated samples showed reduced daily elongation rates and chlorophyll content. Further, these samples showed more than 8-fold increase in the total soluble carbohydrate content. However, the seedling ages did not have a significant influence on the growth of cold-treated seedlings. On the basis of these findings, we can conclude that T. chinensis seedlings aged less than 1 year old show acclimation to cold stress by accumulating soluble carbohydrates. This study may help us understand how T. chinensis seedlings acclimatize to their first cold season.

• BMB Reports
• /
• v.51 no.6
• /
• pp.263-264
• /
• 2018

We identified osteoclast-derived SLIT3 as a new coupling factor using fractionated secretomics. Coupling links bone resorption to bone formation. SLIT3 stimulated the recruitment and proliferation of osteoblasts into bone remodeling sites via activation of ${\beta}-catenin$. Autocrine signaling by SLIT3 also inhibited bone resorption by suppressing the fusion and differentiation of pre-osteoclasts. All mice lacking Slit3 or its receptor Robo1 showed an osteopenic phenotype with low bone formation and high bone resorption. A small truncated recombinant SLIT3 protein increased bone mass in an osteopenic mouse model. These results suggest that SLIT3 is a novel therapeutic target in metabolic bone diseases.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2006.05a
• /
• pp.1252-1255
• /
• 2006

The government has enforced Housing Performance Grade Indication System (Article 21, Paragraph 2 of Housing Act) starting January 2006 for the purpose of giving users in hope of toying an apartment opportunities to select housing based on personal preferences by providing information on housing performance at the time of tenant recruitment announcement as well as securing desirable environment (comfort) by encouraging construction companies to build housing of the indicated performance level. The acoustic performance indication items include three items such as floor impact isolation performance(light weight impact sound, heavy weight impact sound), bathroom noise and insulation performance of boundary walls between households. This paper explains the background, the basis of creation and evaluation method focused on the acoustic environment performance helping for the developer of technique and a staff in charge of construction business who cope with this system.

• Journal of Fisheries and Marine Sciences Education
• /
• v.23 no.3
• /
• pp.503-514
• /
• 2011

Port Authority in Korea does not have financial independence nor fair recruitment practices, thus the prospects of the establishment of the Port Authority is not adequate. Therefore independent and effective port administration cannot be achieved. To overcome this situation, this paper examines the port administration system in Korea and identifies its problems. This paper then provides an 'modeling of Analytical Hierarchy structure' for evaluation. An alternative solution is provided by carrying out a public survey, analysing the significance of the evaluation factor using the techniques of the Analytical Hierarchy Process. The significance of profitability was identified. The role of central government is significant when assessing the public service function of port administration; and the role of the private company is significant when assessing the independence. In addition, the private company is significant when assessing profitability. The private company is the alternative for port administration in Korea, based on the evaluation of various alternatives.

• Journal of Yeungnam Medical Science
• /
• v.35 no.1
• /
• pp.36-39
• /
• 2018

In the personalized medicine era, utilizing paraffin blocks in pathology archives for investigating human diseases has come into the limelight. This archived material with clinical data will reduce the research time and could prevent new patient recruitment to obtain tissue for research. However, the clause indicating the necessity of consent from human material providers in the Korean Bioethics and Safety Act has made the Institutional Review Board (IRB) deny permission to use paraffin blocks for research without consent, and alternatively to get the same before starting an experiment. Written consent may be waived off in studies using paraffin blocks with anonymous status or conditions not linked to personal information by applying the paragraph 3, article 16 of the current Bioethics and Safety Act. Also, the IRB should recommend researchers to preserve the blocks as medical records of patients in long-term archives.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2019.05a
• /
• pp.492-495
• /
• 2019

This study identifies the needs for child care according to population change and movement by region, and analyzes the association with the recruitment rate by type of daycare center to find out the preference of child care facilities by type.

• Journal of the Korean Society of Physical Medicine
• /
• v.5 no.4
• /
• pp.605-613
• /
• 2010

Purpose : The purpose of this study was to investigate the VMO/VL ratio and onset timing using EMG biofeedback training over a 5-day period. Methods : Twenty-one healthy female college students with no known right knee musculoskeletal dysfunction were recruited this study. Muscle activity was measured by surface electromyography(Myosystem 1400A, Noraxon Inc., U.S.A). Statistical analysis was used two-way repeated ANOVA to know difference between the vastus lateralis and vastus medialis oblique onset timing differences, VMO/VL ratio. Results : Biofeedback training group significantly improved VMO/VL ratio and EMG activity of the vastus medialis oblique after intervention. Conclusion : These result indicate that biofeedback training on the vastus medialis oblique has effect on the VMO/VL ratio. EMG biofeedback can be recommended for the facilitation of VMO muscular recruitment.

• Journal of National Security and Military Science
• /
• s.9
• /
• pp.283-311
• /
• 2011

The Republic of Korea, ranked as the 5th military power according to the size of its ground troops, discharges more than 200,000 manpower to the society annually; more than 13,000 of them are officers. The re-employment rate of discharged military personnels, who experience early retirement of 5 to 15 years compared to general public officers, is very low, only amounting to 53.2%. On the other hand, major developed countries exhibit great national scale of effort to take responsibility in helping the settlement of the soldiers who have dedicated their career for their countries. The re-employment rate amounts to 94%. Fully acknowledging such disparity, this paper examines various policies on discharged members support of developed countries, and aims to suggest developmental model on employment support designed for discharged members in the Republic of Korea.

• BMB Reports
• /
• v.50 no.9
• /
• pp.445-453
• /
• 2017

CTCF, Zinc-finger protein, has been identified as a multifunctional transcription factor that regulates gene expression through various mechanisms, including recruitment of other co-activators and binding to promoter regions of target genes. Furthermore, it has been proposed to be an insulator protein that contributes to the establishment of functional three-dimensional chromatin structures. It can disrupt transcription through blocking the connection between an enhancer and a promoter. Previous studies revealed that the onset of various diseases, including breast cancer, could be attributed to the aberrant expression of CTCF itself or one or more of its target genes. In this review, we will describe molecular dysfunction involving CTCF that induces tumorigenesis and summarize the functional roles of CTCF in breast cancer.

• Biomolecules & Therapeutics
• /
• v.22 no.4
• /
• pp.308-313
• /
• 2014

Activator protein-1 (AP-1) is an inducible transcription factor that contributes to the generation of chronic inflammation in response to oxidative and electrophilic stress. Previous studies have demonstrated that the PI3K/Akt1 pathway plays an important role in the transcriptional regulation of AP-1 expression. Although the histone post-translational modifications (PTMs) are assumed to affect the AP-1 transcriptional regulation by the PI3K/Akt pathway, the detailed mechanisms are completely unknown. In the present study, we show that heterochromatin 1 gamma ($HP1{\gamma}$) plays a negative role in TPA-induced c-Jun and c-Fos expression. We show that TPA-induced Akt1 directly phosphorylates $HP1{\gamma}$, abrogates its suppressive function and increases the interaction between histone H3 and 14-3-$3{\varepsilon}$. Collectively, these our data illustrate that the activation of PI3K/Akt pathway may play a permissive role in the recruitment of histone readers or other coactivators on the chromatin, thereby affecting the degree of AP-1 transcription.