• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1333-1337
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• 2014

Background: Astrocytic tumors, the most common primary glial tumors of the central nervous system, are classified from low to high grade according to the degree of anaplasia and presence of necrosis. Despite advances in therapeutic management of high grade astrocytic tumors, prognosis remains poor. In the present study, the frequency and prognostic significance of c-erb-B2 in astrocytic tumors was investigated. Materials and Methods: Records of 72 patients with low- and high-grade astrocytic tumors were evaluated. The expression of C-erbB-2 was determined immunohistochemically and intensity was recorded as 0 to 3+. Tumors with weak staining (1+) or no staining (0) were considered Her-2 negative, while tumors with moderate (2+) and strong (3+) staining were considered Her-2 positive. Results: Of the 72 patients, 41 (56.9%) had glioblastoma (GBM), 10 (13.9%) had diffuse astrocytoma, 15 (20.8%) had anaplastic astrocytoma, 6 (8.3%) had pilocytic astrocytoma. C-erbB-2 overexpression was detected in the tumor specimens of 17 patients (23.6%). Six (8.3%) tumors, all GBMs, exhibited strong staining, 2 (2.7%) specimens, both GBMs, exhibited moderate staining, and 9 specimens, 5 of them GBMs (12.5%), exhibited weak staining. No staining was observed in diffuse astrocytoma and pilocytic astrocytoma specimens. Median overall survival of patients with C-erbB-2 negative and C-erbB-2 positive tumors were 30 months (95%CI: 22.5-37.4 months) and 16.9 months (95%CI: 4.3-29.5 months), respectively (p=0.244). Conclusions: Although there was no difference in survival, C-erbB-2 overexpression was observed only in the GBM subtype.

• Clinical and Experimental Pediatrics
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• v.48 no.10
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• pp.1050-1054
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• 2005

Purpose : Relactation refers to the re-establishment of a milk supply and nursing after the cessation of nursing for a variable period. We aimed to analyze the practical issues related to successful relactation in the lactation clinic. Methods : The medical records of 51 mothers who had visited the lactation clinic for relactation were retrospectively analyzed. Breastfeeding greater than 90% was considered to as relactation success. Perinatal characteristics, the number of visits to the clinic, need for medication and the breastfeeding supplementer, and the reason for failure were analyzed. Results : Relactation appears to be easier for women who had lactated previously. With optimal care, support and motivation, some who had never lactated were able to start lactation. Conclusion : Relactation is a practical method to ensure breastfeeding in motivated women. Supplemental use of drugs and the breastfeeding supplementer system contribute to the success of relactation.

• Quality Improvement in Health Care
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• v.9 no.1
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• pp.74-89
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• 2002

Background : The purpose of this study was to investigate the incidence of unplanned endotracheal extubation and to identify the influencing factor of unplanned extubation in ICUs for providing baseline data in developing prevention strategies and administrative standards. the medical records and hospital information system. In order to analyze factors related to unplanned extubation, the subjects of this study were divided by unplanned extubation group and planned extubation group and were matched by its sex, age, and disease groups in a ratio of one to two. The data were analyzed by descriptive statistics, ${\chi}^2$- test, t-test, Fisher's exact test, and logistic regression analysis with SPSSWIN 10.0 program. Result : 1) Forty-seven(4.99%) of 942 intubated patients experienced unplanned extubation 65 times during the twelve-month period. Thirtyfour( 72.34%) of 47 unplanned extubated patients required reintubation, whereas thirteen patients(27.66%) did not. 2) About half of unplanned extubation(46.8%) occurred during the night shift. 3) As for the nursing activity, respiratory nursing activity score(P=.0.06) and total nursing activity score(P=.011) showed statistically significant differences between unplanned extubation group and planned extubation group. 4) As for the patient status, unplanned extubation group showed more lower consciousness level(P=.000), more irritable or agitated behavior(P=.000), and had more applied physical restraints(P=.000) than planned extubation group. 5) As for the intubation related variables, unplanned extubation group revealed more intubated with respiratory failure(P=.000), more dependent on mechanical ventilation(P=.015) than planned extubation group. 6) Factors affecting unplanned extubations in intensive care unit patients were irritable or agitated behavior(odds ratio=13.757), night shift(odds ratio=7.166), and mechanical ventilation(odds ratio=6.257) from conditional logistic regression analysis. Conclusion : The most affecting factor of unplanned extubation was agitated or irritable behavior. Therefore the results of this study could be helpful to ICU nurses for meticulous care, decision making, timely intervention, and development of intervention strategies for preventing unplanned extubation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.6
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• pp.1245-1255
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• 2009

Recently, to analyze the cause of the railway accident objectively and quickly and prevent the accident, many countries are legislating for the installation of the black box what we call an event recorder, which records information about the operation of railway vehicle. Thus, the study of the event recorder has been in progress. Moreover, the analysis software that can analyze and express the stored data in the event recorder is required for the correct decision on the accident. Therefore, in this paper, we presented a design of analysis software which analyzes the data, plays the audio and video in the event recorder system. This software can quickly and accurately identify the cause of the accident and recognize the driving patterns and habits of the driver according to the operating section. In addition, by analyzing the audio and video data simultaneously in the previous accident, we expect that it is possible to prevent accidents in advance.

• Journal of Korean Neurosurgical Society
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• v.60 no.6
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• pp.755-762
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• 2017

Objective : The purpose of this study is to describe the detailed surgical technique and short-term clinical and radiological outcomes of lateral lumbar interbody fusion (LLIF) and in situ lateral screw fixation using a conventional minimally invasive screw fixation system (MISF) for revision surgery to treat rostral lumbar adjacent segment disease. Methods : The medical and radiological records were retrospectively reviewed. The surgery was indicated in 10 consecutive patients with rostral adjacent segment stenosis and instability. After the insertion of the interbody cage, lateral screws were inserted into the cranial and caudal vertebra using the MISF through the same LLIF trajectory. The radiological and clinical outcomes were assessed preoperatively and at 1, 3, 6, and 12 months postoperatively. Results : The median follow-up period was 13 months (range, 3-48 months). Transient sensory changes in the left anterior thigh occurred in 3 patients, and 1 patient experienced subjective weakness; however, these symptoms normalized within 1 week. Back and leg pain were significantly improved (p<0.05). In the radiological analysis, both the segmental angle at the operated segment and anterior disc height were significantly increased. At 6 months postoperatively, solid bony fusion was confirmed in 7 patients. Subsidence and mechanical failure did not occur in any patients. Conclusion : This study demonstrates that LLIF and in situ lateral screw fixation may be an alternative surgical option for rostral lumbar adjacent segment disease.

• Korean Journal of Oriental Medicine
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• v.18 no.3
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• pp.49-61
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• 2012

This article set out to develop an old Chinese - modern Korean collated terminology by analyzing and paralleling Chinese-Korean translational terms relevant to Korean medicine at a minimum meaning unit from "Eonhaegugeupbang", "Eonhaetaesanjipyo" and "Eonhaetaesanjipyo". Those are composed of original Chinese texts and their subsequent corresponding Korean translations. It tries to make a list of translational standards of Korean medicine terms by classifying the cases of translational ambiguity in terms of disease, body position, thumbnail-pressing acupuncture method, and disease-curing method. The above-mentioned ancient books are medical classics written by Huh Jun, the representative medical physician, and published by the Joseon government. Thus, they are appropriate enough as historically legitimate medical documents, from which are drawn out words and terms to form an old Chinese - modern Korean collation dictionary. This collation glossary will contribute to the increased relevance of data ming, or information retrieval. in a database system and information search engine of massive Korean medical records, by means of providing a novel way to obtaining synchronized results between the original writings of old Chinese and the secondary translated ones of modern Korean. The glossary will promote the collective but consistent translation of numerous old archives of Korean medicine and in other related fields as well.

• Journal of Internet of Things and Convergence
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• v.5 no.2
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• pp.33-39
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• 2019

Entering the 4^th industrial revolution, many technologies are developing and various threats are emerging. In order to cope with such threats, research is being conducted in many fields. Even in the development of various fields, the threats caused by the development of medical technology and intelligent vehicles are the threats to life due to misinformation about medical care and the threats to life by preventing the safe operation of people through intelligent vehicles. In this paper, as the patient's information is important, the private blockchain is used to increase the safety, efficiency, and scalability of the patient's medical records. We propose an information protection technique using blockchain technology to hack the car system and threaten the driver's life, solve privacy problems by identifying personal information and differences, and prevent forgery in the Internet of Things.

• Journal of Korean Library and Information Science Society
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• v.36 no.2
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• pp.327-348
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• 2005

The purpose of this study is to emphasize the importance of index definition and to prepare the basis of optimal index in bibliographic retrieval system. For the purpose, this research studied a index extraction theory on index tag definition and index normalization from the bibliographic marc database and analyzed a retrieval utilization rate of extracted index. In this experiment, we divided index between text-type and code-type about the generated 29,219,853 indexes from 2,200,488 bibliographic records and analyzed utilization rate by the comparison of index-type and index term of web logs. According to the result, the text-type indexes such as title, author, publication, subject are showed high utilization rate while the code-type indexes were showed low utilization rate. So this study suggests that the unused index is removed from index definition to optimize index.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.32-32
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• 2018

Flora investigations in Korea have been conducted by many researchers for diverse purposes. Accumulated flora investigation data has not been utilized efficiently because there is no accessible database for comparison. To overcome this shortcoming, we constructed web-based database of flora investigation, named as the Integrated Korean Flora Database (IKFD; http://www.floradb.net/intro.php). Until now, 284 flora references (263 papers, 14 reports and books, and 7 unpublished papers written in between 1962 and 2017) were digitalized into the database. From 134,711 records, 4,301 species belonging to 228 families and 1,079 genera were identified via mapping with two major Korean plant species lists. Polygon areas originated from references were used for distribution of plant species, identifying precise distribution area. It will be a better index to show plant ecological characteristics. Collected micro-climate data provided by Korea Meteorology Administration were also integrated in IFKD for understanding correlation between distribution of plants and micro-climate. Cold hardiness zone which has been utilized for classifying climate zones. 12 out of 26 zones identified based on micro-climate data in Korea were mapped with distribution of plants. More than half species were appeared in zone 6a, 6b, 7a, and 7b. Taken together with these results, IKFD will be a fundamental platform for understanding plants in Korea flora investigation as well as a new standard for classifying distribution of plants. Moreover, Biodiversity Observation Database (BODB; http://www.biodiversitydb.info/intro.php) which integrates plant distribution data was also integrated for further studies.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8321-8325
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• 2016

Background: The incidence of hydatidiform mole (HM) differs among regions but has declined significantly over time. In Thailand, the initiation of universal health coverage in 2002 has resulted in a change of medical services countrywide. However, impacts of these policies on gestational trophoblastic disease (GTD) cases in Thailand have not been reported. This study aimed to find the incidence of hydatidiform mole (HM) in King Chulalongkorn Memorial Hospital (KCMH) from 1994-2013, comparing before and after the implementation of the universal coverage health policy. Materials and Methods: All cases of GTD in KCMH from 1994-2013 were reviewed from medical records. The incidence of HM, patient characteristics, treatment and remission rates were compared over two study decades between 1994-2003 and 2004-2013. Results: Hydatidiform mole cases decreased from 204 cases in the first decade to 111 cases in the seond decade. Overall incidence of HM was 1.70 per 1,000 deliveries. The incidence of HM in the first and second decades were 1.70 and 1.71 per 1,000 deliveries, respectively (p=0.65, 95%CI 1.54-1.88). Referred cases of nonmolar gestational trophoblastic neoplasia (GTN) increased from 12 (4.4%) to 23 (14.4%, p<0.01). Vaginal bleeding was the most common presenting symptom which decreased from 89.4% to 79.6% (p=0.02). Asymptomatic HM patients increased from 4.8% to 10.2% (p=0.07). Rate of postmolar GTN was 26%. Conclusions: The number of HM cases in this study decreased over 2 decades but incidence was unchanged. Referral rates of malignant cases were more common after universal health coverage policy initiation. Classic clinical presentation was decreased significantly in the last decade.