• Journal of Korea Multimedia Society
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• v.24 no.8
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• pp.1138-1148
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• 2021

In this study, we developed a 'shared-use mobility'-mounted local particulate matter monitoring terminal technology to measure the actual particulate matter concentration around me. As a mobile terminal device in the form of an IoT sensor platform, it is designed to be separated into a control module and a sensor module to minimize interference between sensors and to consider the optimal observation position of each sensor. As a result of the field test, it was confirmed that particulate matter was locally different depending on time and space even within the same area. In addition, it was confirmed that the concentration of particulate matter in the relevant section differed by up to 100 times compared to the surrounding area due to specific sources of particulate matter such as unpaved roads. In addition, we positively reviewed the applicability of the service in the real-time metaverse environment using this result. Through technological advancement and application of multiple shared-use mobilities, we expect to be able to provide new services for practical smart city air environment monitoring, such as localized particulate matter information, air pollution event information, and identification of causes of particulate matter.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.23 no.2
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• pp.121-131
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• 2020

Purpose: To determine the long-term efficacy of the anti-tumor necrosis factor (TNF) agents, infliximab (IFX) and adalimumab (ADA), in pediatric luminal Crohn's disease (CD) by performing a systematic literature review. Methods: An electronic search was performed in Medline, Embase, and the Cochrane Library from inception to September 26, 2019. Eligible studies were cohort studies with observation periods that exceeded 1 year. Studies that reported time-to-event analyses were included. Events were defined as discontinuation of anti-TNF therapy for secondary loss of response. We extracted the probabilities of continuing anti-TNF therapy 1, 2, and 3 years after initiation. Results: In total, 2,464 papers were screened, 94 were selected for full text review, and 13 studies (11 on IFX, 2 on ADA) met our eligibility criteria for inclusion. After 1 year, 83-97% of patients were still receiving IFX therapy. After 2 and 3 years the probability of continuing IFX therapy decreased to 67-91% and 61-85%, respectively. In total, 5 of the 11 studies subgrouped by concomitant medication consistently showed that the probabilities of continuing IFX therapy in patients with prolonged immunomodulator use were higher than those in patients on IFX monotherapy. Conclusion: This review of real-world evidence studies confirms the long-term therapeutic benefit of IFX therapy in diverse cohorts of children with luminal CD. Moreover, it supports the view that combination therapy with an immunomodulator prolongs the durability of IFX therapy in patients who previously failed to recover following first-line therapy. The limited number of time-to-event studies in patients on ADA prevented us from drawing definite conclusions about its long-term efficacy.

• Ocean and Polar Research
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• v.35 no.1
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• pp.15-26
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• 2013

The toxic, Harmful Algal Blooms (HABs) caused by the Cochlodinium polykrikoides have a serious impact on the coastal waters of Korea. In this study, the acoustic detection system was developed for rapid HABs detection, based on the acoustic backscattering properties of the C. polykrikoides. The developed system was mainly composed of a pulser-receiver board, a signal processor board, a control board, a network board, a power board, ultrasonic sensors (3.5 and 5.0 MHz), an environmental sensor, GPS, and a land-based control unit. To evaluate the performance of the system, a trail was done at a laboratory, and two in situ trials were conducted: (1) when there was no red tide, and (2) when there was red tide. In the laboratory evaluation, the system performed well in accordance with the number of C. polykrikoides in the received level. Second, under the condition when there was no red tide in the field, there was a good correlation between the acoustic data and sampling data. Finally, under the condition when there was red tide in the field, the system successfully worked at various densities in accordance with the number of C. polykrikoides, and the results corresponded with the sampling data and monitoring result of NFRDI (National Fisheries Research & Development Institute). From the laboratory and field evaluations, the developed acoustic detection system for early detecting HABs has demonstrated that it could be a significant system to monitor the occurrence of HABs in coastal regions.

• Journal of Astronomy and Space Sciences
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• v.25 no.4
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• pp.471-480
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• 2008

COMS Image Data Acquisition and Control System (IDACS) plays a key role in real time ground processing of Meteorological and Ocean observation data. Beyond processing, it serves processed image data and additional data to end users through the spacecraft in the internationally recommended format. The IDACS will be installed at three location (MSC, KOSC, and SOC) and automatically operated 24h/365days. After the IDACS subsystem tests and inter -subsystem interface tests had been completed in the first half of 2008, the acceptance test which was a comprehensive test performed as an integrated form to verify function performance and operational requirements. This paper introduces test objective, preparation, and major result of the COMS IDACS acceptance test.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.4
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• pp.663-668
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• 2011

Galgeun-tang (GGT) has been a great source for treating cold diseases in the folk medicine recipe. Carbon tetrachloride ($CCl_4$) is one type of hepatotoxin that can eventually cause liver injury. During the experiment, we first studied the protective effects of GGT against $CC_4$-induced hepatotoxicity. GGT was pretreated for 3 h, and 1% $CCl_4$ was added to mouse primary liver cells. After 4 h, ROS generation and expression of antioxidant enzymes (catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx)) were analyzed by FACS and real time PCR. Also, the activities of ALT and LDH were measured using cultured medium. The hepatic levels of TNF-alpha and iNOS, which are related to inflammation and stress response gene, HSP72 and HO-1 were analyzed by PCR or real time PCR. Liver tissues were analyzed by HE stain. From the observation, we discovered that GGT treatment protects $CCl_4$-induced hepatotoxicity, and that GGT pretreatment decreases ROS generation, TNF-alpha and iNOS expression. However, gene expression of CAT, SOD, GPx, HSP72 and HO-1 were increased by GGT. These results lead to the conclusion that GGT has protective effects against $CCl_4$-induced hepatotoxicity.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.39 no.5
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• pp.45-55
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• 2002

In this paper, we describe an outdoor augmented reality system using GPS tracking for position and attitude information. The system consist of a remote mobile operation unit and a ground operation unit. The remote mobile operation unit includes a real-time image acquiring device, a GPS tracking device, and a wireless data transceiver; the ground operation unit includes a wireless transceiver, a virtual image generating device, and an image superimposing device. The GPS tracking device for measurement of position and attitude of the remote mobile operation unit was designed by TANS Vector and RT-20 for DGPS. The wireless data transceiver was for data transmission between the remote mobile operation unit and the ground operation unit. After the remote mobile operation unit was installed on a vehicle and a helicopter, the system was evaluated to verify its validity in actual applications. It was found that the implemented system could be used for obtaining real-time remote information such as construction simulation, tour guide, broadcasting, disaster observation, or military purpose.

• Journal of The Korean Astronomical Society
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• v.47 no.2
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• pp.43-47
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• 2014

Many advanced ground-based solar telescopes improve the spatial resolution of observation images using an adaptive optics (AO) system. As any AO correction remains only partial, it is necessary to use post-processing image reconstruction techniques such as speckle masking or shift-and-add (SAA) to reconstruct a high-spatial-resolution image from atmospherically degraded solar images. In the New Vacuum Solar Telescope (NVST), the spatial resolution in solar images is improved by frame selection and SAA. In order to overcome the burden of massive speckle data processing, we investigate the possibility of using the speckle reconstruction program in a real-time application at the telescope site. The code has been written in the C programming language and optimized for parallel processing in a multi-processor environment. We analyze the scalability of the code to identify possible bottlenecks, and we conclude that the presented code is capable of being run in real-time reconstruction applications at NVST and future large aperture solar telescopes if care is taken that the multi-processor environment has low latencies between the computation nodes.

• Bulletin of the Korean Chemical Society
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• v.31 no.6
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• pp.1561-1567
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• 2010

In this study, we have developed a new detection method using Si field effect transistor (FET)-type biosensors, which enables the direct monitoring of antigen-antibody binding within very high-ionic-strength solutions such as 1$\times$PBS and human serum. In the new method, as no additional dilution or desalting processes are required, the FET-type biosensors can be more suitable for ultrasensitive and real-time analysis of raw sample solutions. The new detection scheme is based on the observation that the strength of antigen-antibody-specific binding is significantly influenced by the ionic strength of the reaction solutions. For a prostate specific antigen (PSA), in some conditions, the binding reaction between PSA and anti-PSA in a low-ionic strength reaction solution such as 10 ${\mu}M$ phosphate buffer is weak (reversible), while that in high-ionic strength reaction solutions such as 1$\times$PBS or human serum is strong.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.17 no.3
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• pp.301-309
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• 1999

Real-time kinematic (RTK) GPS surveying which allows centimeter level accuracy of three-dimensional coordinates without post-processing has become recognized as a major advance in GPS technology. Employing On-The-Fly initialization technique, the RTK system can escape from cycle slip problems that have affected as a main obstacle factor in traditional kinematic and static approaches. The objective of this research was to evaluate accuracy and effectiveness of the RTK-GPS surveying. First, the continuous RTK observation of a base line was conducted for the purpose of finding out the repeatability of the RTK surveying and the results which were then compared against results from static surveying showed RMS errors of $\pm{3mm}\;and\;\pm{13mm}$ for their respective horizontal and vertical components. On a test network of 30 stations covering the small area, the results of RTK testing were compared against those from not only post-processing kinematic and rapid-static surveyings but conventional surveyings and also the efficiency of RTK were analyzed. In addition, geoid heights which were derived by combination of GPS and spirit leveling about all of the points within the network were compared against those derived by the PNU95 and EGM96 models respectively.

• Journal of Korea Water Resources Association
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• v.54 no.6
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• pp.381-393
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• 2021

As part of the National Disaster Management Research Institute's Official Development Assistance (ODA) projects for transferring new technologies in the field of disaster-safety management, a flood forecasting and warning system was established in 2019 targeting the Borikhan in the Namxan River Basin in Bolikhamxai Province, Laos. In the target area, which is an ungauged small and medium river basin, observation stations for real-time monitoring of rainfall and runoff and alarm stations were installed, and a software that performs real-time data management and flood forecasting and warning functions was also developed. In order to establish a flood warning standard and develop a nomograph for flood prediction, hydraulic and hydrological analysis was performed based on the 30-year annual maximum daily rainfall data and river morphology survey results in the target area. This paper introduces the process and methodology used in this study, and presents the results of the system's applicability review based on the data observed and collected in 2020 after system installation.