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Development and Validation of Analytical Method for Pectolinarin and Pectolinarigenin in Fermented Cirsium setidens Nakai by Bioconversion (생물전환에 의한 발효 고려엉겅퀴 Pectolinarin 및 Pectolinarigenin의 분석법 개발 및 검증)

  • Oh, Ji-Won;Lee, Jin-Ha;Cho, Myoung-Lae;Shin, Gi-Hae;Kim, Jae-Min;Choi, Sun-Il;Jung, Tae-Dong;Kim, Young-Hyun;Lee, Sang-Jong;Lee, Bong Jin;Park, Seon Ju;Lee, Ok-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.10
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    • pp.1504-1509
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    • 2015
  • The aim of this study was to investigate a validation method for determination of pectolinarin and pectolinarigenin in fermented Cirsium setidens Nakai. For validation, the specificity, linearity, precision, accuracy, detection limits, and quantification limits of pectolinarin and pectolinarigenin were measured by HPLC. The results show that the detection limits of pectolinarin and pectolinarigenin were $4.25{\mu}g/mL$ and $2.46{\mu}g/mL$, respectively. The recovery rates of pectolinarin and pectolinarigenin were high in the ranges of 99.7~104.0% and 99.7~102.4%, respectively. Inter-day and intra-day precisions of pectolinarin and pectolinarigenin in fermented Cirsium setidens Nakai were 0.9%, 0.5% and 0.5%, 0.2%, respectively. Therefore, application of pectolinarin and pectolinarigenin was validated by an analytical method as a marker compound in Cirsium setidens Nakai.

DIRECT PULP CAPPING WITH BONDING RESIN (접착용 레진을 이용한 유치의 직접 치수복조술에 관한 연구)

  • Cho, Hae-Sung;Choi, Yeong-Chul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.33 no.2
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    • pp.165-172
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    • 2006
  • A direct pulp capping with different medicaments has been attempted for a long time. The most commonly used among those is the calcium hydroxide. In primary teeth, however, a success rate of direct pulp capping with calcium hydroxide has been reported to be lower than that of pulpotomy. The disappointing results of calcium hydroxide have prompted the search for other capping materials. Lately, several researchers suggested an application of adhesive resin-based composite systems as a capping material. They claimed that when an exposed vital pulp is capped directly with bonding resin, the pulp tissue is free of inflammation or necrosis without clinical symptoms. The aim of this study was to compare short-term effects of the bonding resin which was applied on the mechanically exposed vital pulp tissue and those of direct pulp capping with calcium hydroxide. The second objective was to compare success rates of the primary teeth which already underwent physiologic root resorption and those of the teeth which had not undergone physiologic root resorption yet, in each capping material groups. The vital, healthy pulp of forty-one primary teeth were exposed mechanically during a cavity preparation. They were divided into two groups: Group 1(n=21) underwent capping with bonding resin, and group 2(n=20) underwent capping with calcium hydroxide. Then these two groups were subdivided into two groups in each : the teeth which show physiologic root resorption and the teeth without root resorption. All of the sample teeth were restored with composite resin. Clinical evaluations such as percussion test, ice test, EPT, were recorded and also before- and after- standard x-ray films were compared and evaluated to decide whether the case was successful or not. Evaluation was performed at least 3 months after the capping materials. The results were as follows 1. There was no difference in success rate between group 1 and group 2. 2. Success rate of the teeth with physiologic root resorption was higher than that of the teeth without physiologic root resorption in group 1 and group 2. 3. There was no difference in success rate between anterior teeth and posterior teeth.

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Effects of Different Levels of Hilly Inclination and Nitrogen, Phosphorus and Potassium Application Rate on the Mutual Balances of Mineral Nutrients in Pasture Soils and Mixed Forages, and the Grass Tetany Hazard in a Mixed Grass-Clover Sward (산지경사도(山地傾斜度) 및 3요소(要素) 시용수준(施用水準)이 초지토양(草地土壤) 및 목초중(牧草中) 무기양분(無機養分)의 상호균형(相互均衡)과 Grass Tetany 위험성(危險性)에 미치는 영향(影響))

  • Jung, Yeun-Kyu;Lee, Jong-Yeol
    • Korean Journal of Soil Science and Fertilizer
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    • v.19 no.3
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    • pp.231-238
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    • 1986
  • This field experiment was undertaken to assess the effects of three levels of inclination ($10^{\circ}$, $20^{\circ}$ and $30^{\circ}$) and four rates of $N-P_2O_5-K_2O$ (0-0-0, 14-10-10, 28-25-25, and 42-40-40 kg/10a) on the hilly pasture concerning to establishment, forage yield and quality, and botanical composition in the mixed grass-clover sward set up on a new reclaimed woodland by an oversowing method. This part was concerned with the concentration and mutual balance of mineral nutrients in relation to grass tetany hazard. The results obtained were summarized as follows: 1. Concentration of exchangeable Mg, relative proportions of Mg to CEC, K, and Ca in soil were considerably below the critical level for good forage growth and prevention of grass tetany. These properties were rather worsened by increasing the inclination grade and the NPK rate. 2. Compared with the critical level for the likelihood of tetany (Mg < 0.2%, K > 2.5%, and K/(Ca+Mg) equivalent ratio > 2.2 in forages in DM basis), mean concentration of Mg in mixed forages turned out to range from 0.09 to 0.14%. 2.6% of K concentration and 2.5 of K/(Ca+Mg) equivalent ratio were shown to be at a normal NPK rate. The likelihood of grass tetany was generally enhanced by increasing the inclination grade and the NPK rate. 3. The increasing of the inclination grade and NPK rate rather aggravated the low Mg concentration and unbalanced mutual ratios of mineral nutrients, from which resulted the grass tetany hazard and the depression of forage growth. To prevent these two resulted factors, Mg fertilization on grassland and/or extra Mg supplement to dairy cattle needed to be carried out. 4. The Ca/P ratios in the mixed forages ranging from 1.0 to 2.0 were reduced by the increased rate of NPK, whereas the difference due to inclination grade was yet to be recognized.

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Characteristics and Implications of 4th Industrial Revolution Technology Innovation in the Service Industry (서비스 산업의 4차 산업혁명 기술 혁신 특성과 시사점)

  • Pyoung Yol Jang
    • Journal of Service Research and Studies
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    • v.13 no.2
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    • pp.114-129
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    • 2023
  • In the era of the 4th industrial revolution, the importance of the 4th industrial revolution technology is increasing in the service industry. The purpose of this study is to identify the development and utilization status of the 4th industrial revolution technology in the service industry and to derive the characteristics and implications of the 4th industrial revolution technology innovation in the service industry. In this study, research and analysis were conducted based on the business activity survey data in order to identify the technological innovation characteristics of the 4th industrial revolution in the service industry. The 4th industrial revolution technology in the service industry was analyzed in terms of company ratio, technology development and utilization rate, development/utilization technology, technology application field, and technology development method. In addition, the trend of the 4th industrial revolution technology change in the service industry was also analyzed. The 4th industrial revolution technology utilization and development status of other industries was compared and analyzed. In particular, the service industry 4th industrial revolution technology innovation type was divided into 4 types from the perspective of the 4th industrial revolution company ratio and the 4th industrial revolution company ratio growth rate, and types for each service industry were derived. The characteristics and implications of the 4th industrial revolution technology innovation in the service industry were presented from nine perspectives. As a result of the study, it was found that companies in the service industry were developing or using 4th industrial revolution technologies more actively than companies in other industries, and it was analyzed that the gap was further widening. By service industry, information and communication, finance and insurance, and educational service showed relatively high rates of developing or utilizing 4th industrial revolution technologies. The service industries in which the share of 4th industrial revolution companies increased the most were real estate, education service, health and social welfare service. In particular, cloud, big data, and artificial intelligence were analyzed as the three core technologies of the fourth industrial revolution. The service industry can be classified into 4 types in terms of the 4th industrial revolution company ratio and growth rate, and service industry innovation measures that reflect the differentiated innovation characteristics of each type are needed.

Literature Review on Applying Digital Therapeutic Art Therapy for Adolescent Substance Addiction Treatment (청소년 마약류 중독 치료를 위한 디지털치료제 예술치료 적용을 위한 문헌연구)

  • Jiwon Kim;Daniel H. Byun
    • Trans-
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    • v.16
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    • pp.1-31
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    • 2024
  • The advent of digital media has facilitated easy access for adolescents to environments conducive to the purchase of narcotics. In particular, there's an increasing trend in the purchase and consumption of narcotics mediated through Social Network Services (SNS) and messenger services. Adolescents, sensitive to such environments, are at risk of experiencing neurological and mental health issues due to narcotic addiction, increasing their exposure to criminal activities, hence necessitating national-level management and support. Consequently, the quest for sustainable treatment methods for adolescents exposed to narcotics emerges as a critical challenge. In the context of high relapse rates in narcotic addiction, the necessity for cost-effective and user-friendly treatment programs is emphasized. This study conducts a literature review aimed at utilizing digital platforms to create an environment where adolescents can voluntarily participate, focusing on the development of therapeutic content through art. Specifically, it reviews societal perceptions and treatment statuses of adolescent drug addiction, analyzes the impact of narcotic addiction on adolescent brain activity and cognitive function degradation, and explores approaches for developing digital therapeutics to promote the rehabilitation of the addicted brain through analysis of precedential case studies. Moreover, the study investigates the benefits that the integration of digital therapeutic approaches and art therapy can provide in the treatment process and proposes the possibility of enhancing therapeutic effects through various treatment programs such as drama therapy, music therapy, and art therapy. The application of art therapy methods is anticipated to offer positive effects in terms of tool expansion, diversification of expression, data acquisition, and motivation. Through such approaches, an enhancement in the effectiveness of treatments for adolescent narcotic addiction is anticipated. Overall, this study undertakes foundational research for the development of digital therapeutics and related applications, offering economically viable and sustainable treatment options in consideration of the societal context of adolescent narcotic addiction.

Difference of Absorption and Anatomical Responses to Protoporphyrinogen Oxidase-Inhibiting Herbicides in Wheat and Barley (Protoporphyrinogen Oxidase 저해형 제초제에 대한 밀과 보리의 흡수 및 해부하적 차이)

  • 구자옥;국용인
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.42 no.1
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    • pp.68-78
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    • 1997
  • Laboratory and greenhouse studies were conducted to determine differential sensitivities on absorption of $^{14}$ C-oxyfluorfen and the anatomical responses in wheat and barley to protoporphyrinogen oxidase-inhibiting herbicides [oxyfluorfen (2-chloro-1- (3-ethoxy -nitrophen-oxy)-4-(trifluoromethyl) benzene, acifluorfen(5-[2-chloro-4-(trifluoromethyl) phenoxy]-2-nitro-benzoic acid), bifenox(methyl-5-(2, 4-dichlorophenoxy)-2-nitrobenzoate) and oxadiazon(5-tert-butyl-3-(2, 4-dichloro-5-isopropoxyphenyl)-1, 3, 4-oxadiazol-2-one)]. I$_{50}$ value of the tolerant wheat cultivars to oxyfluorfen was about 10$^{-4}$ , whereas that of the susceptible barley cultivars was about 10$^{-6}$ M, showing significant difference between the two groups. When foliage were applied with acifluorfen, bifenox or oxadiazon, the oxyfluorfen-tolerant wheat showed less decreased in shoot fresh weight and chlorophyll content than the susceptible barley. Also, when soil-applied with these herbicides test plants showed similar tendency in foliar application. Electrolyte leakage from the tissue treated with these compounds was the more influenced in the barley than the wheat. Malondialdehyde(MDA) production as index of lipid peroxidation was greater in the barley than the wheat by treatment of these compounds. Therefore, the differential sensitivities of wheat and barley to protoporphyrinogen oxidaseinhibiting herbicides was showed by our greenhouse and in vitro experiment. The absorption rates of $^{14}$ C-oxyfluorfen were higher in the barley than the wheat. And this tendency was showed appararitly difference by increase of treatment durations. After the oxfluorfen and oxadiazon treatment, the tolerant wheat did not show the structural damage in leaf surface, but the susceptible barley was damaged in the leaf waxy layer. However, the acifluorfen and bifenox treatment showed no difference between wheat and barley. The anatomical changes by these compounds treatment were not observed in the tolerant wheat but epidermal cell and mesophyll cell were highly broken in the susceptible barley.

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Studies on Tip-burn of Chinese Cabbage by Ammonium Toxicity (암모니움 Toxicity에 의(依)한 배추의 Tip-burn에 관(關)한 연구(硏究))

  • Lee, Sang-Eun;Lim, Sookil H.
    • Korean Journal of Soil Science and Fertilizer
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    • v.17 no.4
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    • pp.389-398
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    • 1984
  • The effect of N forms ($NO_3{^-}-N$, $NH_4{^+}-N$) and concentrations (4, 8, $16meq/{\ell}$) which were changed at head formation stage on the tip-burn incidence of chinese cabbage was studied under the three levels (0, 8, 16 meq/l) of Ca. All of the plants grown on $NH_4{^+}-N$ showed the symptoms of tip-burn and low yields regardless of Ca levels. Roots of plants grown on $NH_4{^+}-N$ were severely damaged. The pH of the leachate from $NH_4{^+}-N$ pot was decreased to below pH 5. Plants which had been grown on $NH_4{^+}-N$ before the head formation stage, but changed to $NO_3{^-}-N$ were recovered from abnormal growth. But, the reverse showed the tip-burn symptoms. $NH_4{^+}-N$ treatments increased the T-N contents, but lowered K and Ca contents of inner leafblades. Icreased applications of Ca did not affect the T-N and K contents of the inner leafblades. $NH_4{^+}-N$ suppressed Ca translocation into the inner leaves from outer leaves after the head formation stage, but $NO_3{^-}-N$ accelarated it. Ca contents were much lower in leaves showing tip-burn symptoms than in healthy leaves. Internal rot which is a tip-burn symptom occuring after head formation were noted in plants applied with high concentration of $NO_3{^-}-N$ both before and after the head formation stage. Ca contents correlated well with the rates of Ca application, but there was no correlation between ca conents and internal rot incidence. Chinese cabbage tip-burn is not caused by Ca deficiency, as is commonly believed, but rather by the water stress (95% water contents in $NO_3{^-}$-fed plants, 91% in $NH_4{^+}$-fed plants) resulting from root damage caused by ammonium toxicity. Internal rot is also caused by excess applications of nitrogen, and is unaffected by calcium levels.

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Effect of Potassium on Corn(Zea mays L.) Seedling Growth under Nutrient Solution Culture (양액재배시(養液栽培時) 칼륨 농도(濃度)가 옥수수(Zea mays L.) 생육(生育)에 미치는 영향(影響))

  • Oh, Jong-Seo;Kim, Moo-Sung;Kim, Se-Young
    • Korean Journal of Soil Science and Fertilizer
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    • v.29 no.1
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    • pp.26-33
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    • 1996
  • A nutrient solution culture experiment was conducted in the greenhouse at Suwon Campus. Kyung-Hee University from May 23 to July 11. 1995, to determine the effects of potassium application on seedling growth of Kwanganok and Hwengsungok cultivars of corn. Potassium was treated with four different levels, which are 0.248.496 and 744ppm for treatments without potassium (-k), standard potassium concentration (K), double(2k) and triple (3k) of standard potassium concentration, respectively. Plants were harvested at weekly interval for seven weeks. at which time plant height, leaf area and dry matter yield of corn seedling were measured, only chlorophyll content was taken for five weeks from three week after planting. Seedlings growth of Kwanganok and Hwengsungok cultivars was greatly retarded from planting to harvesting time in 3k treatment. The plant height, leaf area and dry matter yield of both cultivars during the whole period were decreased in order of K>2F>-K>3K, but dry matter yield of Kwanganok cultivar was decreased in order of 2K>K>-K>3K. Chlorophyll content of Kwanganok and Hwengsungok cultivars was irregularly fluctuated during growing period. but generally highest in K treatment and lowest in 3k treatment. The crop growth rates of seedlings of both cultivars were slow until the 3rd week after planting. but very fast thereafter. In general, CGR of both cultivars was higher in K and 2k treatments than -k and 3k treatments.

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Method of Elastic Constant Measurement for Transversely Isotropic Rocks: Application to Banded Gneiss of the Onyang Region (온양지역에 분포하는 호상편마암을 이용한 평면 이방성 암석의 탄성상수 측정방법)

  • Jang, Hyun-Sic;Lee, Ok-Top;Jang, Bo-An
    • The Journal of Engineering Geology
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    • v.22 no.3
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    • pp.309-321
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    • 2012
  • Elastic constants were measured for 70 samples of transversely isotropic banded gneiss from the Onyang region. Anisotropic angles of samples are $0^{\circ}$, $15^{\circ}$, $30^{\circ}$, $45^{\circ}$, $60^{\circ}$, $75^{\circ}$ and $90^{\circ}$. Exact values of $E_2$ and ${\nu}_{21}$ can be measured from samples with anisotropic angles of $0^{\circ}$ and those of $E_1$ and ${\nu}_{12}$ from samples with anisotropic angles of $90^{\circ}$. These values are set as reference values. Elastic constants measured from samples with anisotropic angles of $15^{\circ}$, $30^{\circ}$, $45^{\circ}$, $60^{\circ}$, and $75^{\circ}$, using the methods proposed by Jang et al. (2001) and Park et al. (2008), are compared with the reference values to examine the effectiveness of the two methods. $E_1$ were measured correctly from samples with anisotropic angles of $60^{\circ}$ and $75^{\circ}$, and $E_2$ from samples with anisotropic angles of $15^{\circ}$ and $30^{\circ}$, when using the method suggested by Jang et al. (2001). $E_1$ were measured correctly from samples with anisotropic angles of $45^{\circ}$ and $60^{\circ}$, and $E_2$ from samples with anisotropic angles of $15^{\circ}$, $30^{\circ}$, and $60^{\circ}$, when using the method proposed by Park et al. (2008). The effectiveness of the two methods was determined by error rates between exact values and measured values. The effectiveness of the two methods was similar. However, the method suggested by Jang et al. (2001) may be more effective in measuring $E_1$, while the method suggested by Park et al. (2008) may be more effective in measuring $E_2$.

The progress in NF3 destruction efficiencies of electrically heated scrubbers (전기가열방식 스크러버의 NF3 제거 효율)

  • Moon, Dong Min;Lee, Jin Bok;Lee, Jee-Yon;Kim, Dong Hyun;Lee, Suk Hyun;Lee, Myung Gyu;Kim, Jin Seog
    • Analytical Science and Technology
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    • v.19 no.6
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    • pp.535-543
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    • 2006
  • Being used widely in semiconductor and display manufacturing, $NF_3$ is internationally considered as one of the regulated compounds in emission. Numerous companies have been continuously trying to reduce the emissions of $NF_3$ to comply with the global environmental regulation. This work is made to report the destruction and removal efficiency (DRE) of electrically heated scrubbers and the use rate in process chambers installed in three main LCD manufacturing companies in Korea. As the measurement techniques for $NF_3$ emission, mass flow controlled helium gas was continuously supplied into the equipment by which scrubber efficiency is being measured. The partial pressures of $NF_3$ and helium were accurately measured for each sample using a mass spectrometer, as it is emitted from inlet and outlet of the scrubber system. The results show that the DRE value for electrically heated scrubbers installed before 2004 is less than 52 %, while that for the new scrubbers modified based on measurement by scrubber manufacturer has been sigificentely improved upto more than 95 %. In additon, we have confirmed the efficiency depends on such variables as the inlet gas flow rate, water content, heater temperature, and preventative management period. The use rates of $NF_3$ in process chambers were also affected by the process type. The use rate of radio frequency source chambers, built in the $1^{st}$ and $2^{nd}$ generation process lines, was determined to be less than 75 %. In addition, that of remote plasma source chambers for the $3^{rd}$ generation was measured to be aboove 95 %. Therefore, the combined application of improved scrubber and the RPSC process chamber to the semiconductor and display process can reduce $NF_3$ emmision by 99.95 %. It is optimistic that the mission for the reduction of greenhouse gas emission can be realized in these LCD manufacturing companies in Korea.