• Title/Summary/Keyword: Rate of volume increase

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Blood Gas Analysis of Respiratory Depression during Sevoflurane Inhalation Induction for General Anesthesia in the Disabled Patients (장애 환자의 전신 마취를 위한 세보플루란 흡입 유도 시 발생한 호흡 저하의 혈액 가스 분석)

  • Yoon, Taewan;Kim, Seungoh
    • Journal of the korean academy of Pediatric Dentistry
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    • v.45 no.4
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    • pp.508-513
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    • 2018
  • Tidal volume by sevoflurane in small amounts is stable due to the increase in the breathing rate. But alveolus ventilation decreases due to sevoflurane as the degree of sedation increases; this ultimately causes $PaCO_2$ to rise. The occurrence of suppression of breath increases the risk of severe hypoxia and hypercapnia in deeply sedated patients with disabilities. Sevoflurane inhalation anesthesia has a number of risks and may have unexpected problems with hemodynamic changes depending on the underlying state of the body. This study was conducted to examine the stability of internal acid-base system caused by respiratory depression occurring when patients with disabilities are induced by sevoflurane. Anesthetic induction was carried out by placing a mask on top of the patient's face and through voluntary breathing with 4 vol% of sevoflurane, 4 L/min of nitrous oxide, and 4 L/min of oxygen. After the patient's loss of consciousness and muscle relaxation, IV line was inserted by an expert and intravenous blood gas was analyzed by extracting blood from vein. In a deeply sedated state, the average amount of pH of the entire patients was measured as $7.36{\pm}0.06$. The average amount of $PvCO_2$ of the entire patients was measured as $48.8{\pm}8.50mmHg$. The average amount of $HCO_3{^-}$ of the entire patients was measured as $27.2{\pm}3.0mmol/L$. In conclusion, in dental treatment of patients with disabilities, the internal acid base response to inhalation sedation using sevoflurane is relatively stable.

Evaluation of Respiration Reproducibility of Chest General X-ray Examination using Self-made Respiratory Synchronization Device (자체 제작한 호흡 동기화 장치를 통한 흉부 일반촬영 검사의 호흡 재현성 평가)

  • Kwon, Oh-Young;Lee, Chang-Hun;Yong, Keum-Ju;Jin, Seon-Hui;Jung, Da-Bin;Heo, Yeong-Cheol
    • Journal of the Korean Society of Radiology
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    • v.15 no.7
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    • pp.1049-1056
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    • 2021
  • The purpose of this study was to develop a respiratory synchronization device for X-ray (X-RSD) to increase the reproducibility of inspiration when examining the Chest X-ray of a patient who difficulty in breathing coordination. The X-RSD was self-made using an air pressure sensor and air was injected by connecting a ventilator to the mannequin for CPR. At this time, the amount of injected air was quantified using the SkillReporting device. After placing the X-RSD on the chest of the mannequin, the amount of air was tested in 6 steps from 200 to 700 cc by 100 cc increased. For the accuracy evaluation, the sensitivity of X-RSD was measured by repeating a total of 80 measurements, and the sensitivity was 100%, and very precise results were obtained. After that, the images examined while viewing the X-RSD of the chest lateral examination and the images obtained by the blind examination were compared and evaluated. The lung volume of X-RSD was larger than that of the blind test, and the deviation was smaller. Overall, the use of X-RSD can help with chest X-ray examination of patients who have difficulty in cooperating, and it is thought that it will be possible to contribute to the reduction of exposure dose by reducing the repeat rate of general X-ray examinations.

The Productivity and Cost of Yarding Operations Using a Tractor-attached Winch in Pinus densiflora Stands (소나무 임분에서의 트랙터윈치를 이용한 집재작업 생산성 및 비용분석)

  • Jeong, Eung-Jin;Cho, Min-Jae;Park, Jeong-Mook;Cho, Koo-Hyun;Yoo, Young-Min;Cha, Du-Song
    • Journal of Korean Society of Forest Science
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    • v.108 no.4
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    • pp.574-581
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    • 2019
  • The present study analyzed the productivity and cost of winching operations for evaluating the efficiency of a tractor-attached winch in a Pinus densiflora thinning site located in the Yangyang County of Gangwon-do. The mean yarding distance and mean timber volume were 29 m and 0.15 ㎥, respectively. In the 95 cycles of yarding operations, the uphill and downhill yarding operations constituted 51% and 49%, respectively, of the total yarding operations. The productivity of the uphill yarding operation was 2.28 ㎥/h, and the productivity of the downhill yarding operation was 1.89 ㎥/h. The findings of this study revealedthat productivity would increase by 0.5 ㎥/h when the rate of utilization of the machine is increased to 80% by reducing the operational delay time. The cost of the downhill yarding operation was 44,116 KRW/㎥, whereas that of the uphill yarding operation was 53,369 KRW/㎥. The difference in cost resulted from the difference in the number of yarding stems (stems/cycle). Furthermore, the results of the multiple linear regression equation developed for predicting the yarding operation times showed that productivity was significantly affected by working conditions such as yarding distance (m), the number of stems per cycle (stems/cycle), and the terrain slope (%) in the uphill and downhill yarding operations. Further research is required for developing an accurate prediction model equation according to a yarding direction.

Preparation and Characterization of Iron Phthalocyanine Thin Films by Vacuum Sublimation (진공증착법을 이용한 철프탈로시아닌 박막의 합성과 그 특성)

  • Jee, Jong-Gi;Lee, Jae-Gu;Hwang, Dong-Uk;Lim, Yoon-Mook;Yang, Hyun-Soo;Ryu, Haiil;Park, Ha-Sun
    • Applied Chemistry for Engineering
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    • v.10 no.5
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    • pp.644-651
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    • 1999
  • In this experiment the Iron phthalocyanine (FePc) films on Si-wafer and alumina pallet were prepared using vacuum sublimation with conditions of changing reaction time, temperature, and deposition rate. Then, some samples were annealed following annealing. Techniques such as XRD, SEM, and resistance measurement method, were dedicated to characterize the changes of surface structure, phase transformation and electric resistance sensitivity in accordance with change of film thickness. In proportion to the decrease of deposition temperature from $370^{\circ}C$ to $350^{\circ}C$, intensities of (200), (011), (211) and (114) planes of $\alpha$-phase were decreased and (100) plane of $\beta$-phase were appeared. The film thickness were controlled by regulating the volume of precursor material during rapid deposition. As a result, it was observed that crystalline particle size had been increased according to the increase of film thickness and $\alpha$-phase transformed to $\beta$-phase. In consequence of measuring the crystallinity of films annealed between $150^{\circ}C$ and $350^{\circ}C$, $\alpha$- to $\beta$-phase transformation was appeared to begin at $150^{\circ}C$ and completely transformed to $\beta$-phase at $350^{\circ}C$. Electric resistance sensitivity of FePc film to $NO_x$ gas along temperature change of FePc films was observed to be more stable with the decrease of the film thickness.

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ITZ Analysis of Cement Matrix According to the Type of Lightweight Aggregate Using EIS (EIS를 활용한 경량골재 종류별 시멘트 경화체의 계면특성 분석)

  • Kim, Ho-Jin;Jung, Yoong-Hoon;Bae, Je-Hyun;Park, Sun-Gyu
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.4
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    • pp.498-505
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    • 2020
  • Aggregate occupies about 70-85% of the concrete volume and is an important factor in reducing the drying shrinkage of concrete. However, when constructing high-rise buildings, it acts as a problem due to the high load of natural aggregates. If the load becomes large during the construction of a high-rise building, creep may occur and the ground may be eroded. Material costs increase and there are financial problems. In order to reduce the load on concrete, we are working to reduce the weight of aggregates. However, artificial lightweight aggregates affect the interface between the aggregate and the paste due to its higher absorption rate and lower adhesion strength than natural aggregates, affecting the overall strength of concrete. Therefore, in this study, in order to grasp the interface between natural aggregate and lightweight aggregate by type, we adopted a method of measuring electrical resistance using an EIS measuring device, which is a non-destructive test, and lightweight bone. The change in the state of the interface was tested on the outside of the material through a blast furnace slag coating. As a result of the experiment, it was confirmed that the electric resistance was about 90% lower than that in the air-dried state through the electrolyte immersion, and the electric resistance differs depending on the type of aggregate and the presence or absence of coating. As a result of the experiment, the difference in compressive strength depending on the type of aggregate and the presence or absence of coating was shown, and the difference in impedance value and phase angle for each type of lightweight aggregate was shown.

Quality Characteristics of Pound Cakes Prepared with Flowering Cherry (Prunus serrulata L. var. spontanea Max. wils.) Fruit Powder during Storage (버찌(Fruit of Prunus serrulata L. var. spontanea Max. wils.) 분말을 첨가한 파운드케이크의 저장 중 품질 특성)

  • Kim, Kyoung-Hee;Hwang, Hye-Rim;Yun, Mi-Hyang;Jo, Ji-Eun;Kim, Mi-Seon;Yook, Hong-Sun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.7
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    • pp.926-934
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    • 2009
  • The study investigated the quality of pound cake prepared with various concentrations of cherry powder (obtained from ground fruit of Prunus serrulata L. var. spontanea Max. wils.). Pound cake was evaluated for their sensory property and physical quality stored for 10 days at $25^{\circ}C$. The pH of the batter decreased with rising cherry powder concentration. The specific loaf volume and height decreased (from 2.95 to $2.60\;cm^3/g$) with increasing in cherry powder. The baking loss rate of the pound cake tended to increased by $11.47{\sim}12.67%$, but with no significant differences. The lightness, redness, and yellowness values were significantly decreased with increases in cherry powder except for redness of pound cake crumb. As the concentration of cherry powder increased, the mechanical characteristics of the pound cake did not differ significantly. The hardness tended to increase, while adhesiveness and springiness decreased with increases in powder. The retrogradation degree of pound cake prepared with cherry powder was higher than the control but there were no significant differences. For the antioxidative activity measured by DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity, pound cake prepared with 10% and 15% added cherry powder showed high antioxidant activities. The pound cakes containing 10 and 15% cherry powder had acceptable sensory properties, such as flavor, taste, softness, moisture, and overall acceptability. The results exhibited that adding the cherry powder into the pound cake increased antioxidant activity with the highest quality improvement obtained by incorporating 10% (w/w) of cherry powder into the pound cake formula.

Immunological Aspects of Contemporary Exercise (운동과 면역반응에 대한 고찰)

  • Kwak, Yi-Sub;Kim, Chul-Woo;Paik, Young-Ho
    • Journal of Life Science
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    • v.17 no.8 s.88
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    • pp.1166-1171
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    • 2007
  • Exercise is the strongest stress to which the body is ever exposed. The body responds to this stress through a set of physiological changes in its metabolic, hormonal, and immunological systems. In this study, responses of the immune system to the long-term aerobic and anaerobic exercises have been investigated. Regular moderate exercise is associated with a reduced incidence of infection compared with a sedentary groups. Aerobic training increases the heart rate and enhances the body's intake of oxygen long enough to benefit the condition of the body. In recent years, the importance of exercise in everyday life has been rapidly increasing. Moderate exercise appears to stimulate the immune system. And also, Exercise elicits an increase in the numbers of circulating lymphocytes and lymphocyte subsets (including NK cells) which is followed by a decrease in the numbers of cells during recovery from exercise. However, prolonged bouts of strenuous exercise cause a temporary depression of various aspects of immune functions (e.g. lymphocyte proliferation, monocyte antigen presentation, open window periods, exercise induced asthma, exercise induced anaphylaxis) that usually lasts 2-24 hr after exercise depending on the intensity and duration of the exercise bout. Exercise-induced bronchoconstriction (EIB) was defined as a decrease of at least 15% in pre exercise forced expiratory volume in one second at any time point after exercise. This includes elevation of cortisol and cathecholamines in plasma. On the other hand, highly trained athletes exhibit a chronic mild hypercortisolism at baseline that maybe an adaptive change to chronic exercise. And, Consuming carbohydrate during prolonged strenuous exercise attenuates rises in stress hormones and appears to limit the degree of exercise-induced immune depression. Recent evidence suggests that antioxidant vitamin supplementation may also reduce exercise stress and impairment of leukocyte functions.

Pharmacokinetic Preformulation Study of rH IL-2 (인터루킨-2의 제제설계를 위한 체내 동태학적 연구)

  • Seo, Min-Seok;Shim, Chang-Koo;Kwon, Jong-Bum;Na, Do-Sun;Lee, Sun-Bok;Hahm, Kyung-Soo;Han, Moon-Hi
    • YAKHAK HOEJI
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    • v.34 no.4
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    • pp.238-243
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    • 1990
  • Pharmacokinetic characteristics of recombinant human interleukin-2 (rH IL-2) wre studied in the rat. First, different doses of rH IL-2 ranging from 6,400 to 1,600,000 U/kg were injected intravenously and the effect of dose size on the pharmacokinetics was examined. There was no dose dependency in the pharmacokinetics of rHIL-2 in the dose range of 6,400-40,000 U/kg. But at the dose of 1,600,000 U/kg, there was a severe hemolysis throughout the experiment and the pharmacokinetic parameters such as Vdss and CLt were significantly increased compared to those obtained from lower doses. It also showed that this drug is hardly distributed to the peripheral tissues and hardly eliminated from the body, since the valume of distribution (Vdss) and total body clearance (CLt) were 45-75 ml/kg and 1-2 ml/min/kg, respectively. The Vdss is close to the actual plasma volume and the CLt is less than glomerular filtration rate (GFR). Therefore it seemed that rH IL-2 is distributed only in the plasma pool and hardly filtered in the kidney due to its very large molecular weight. Second, rH IL-2 was administered to the rat via several routes such as hepatic portal vein (PV), intraperitoneal (IP), peroral (PO) and intranasal (IN) routes. The bioavailabilities (BA) of PV, IP, PO and IN routes were 96.8, 4.9, 0 and 0.1%, respectively. The addition of some nasal absorption enhancers such as taurocholate, taurodeoxycholate, glycocholate and glycodeoxycholate did not increase the BA of intranasaly administered rH IL-2. The result is contrast to the effect of these bile salts on the nasal absorption of ${\alpha}-inteferon$. Considering it together with the pharmacokinetic parameters, very large molecular weight of rH IL-2 seemed again to be the cause to very poor membrane permeability.

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Earthquake-Resistant Design of Cantilever Retaining-Walls with Sloped Base (기초슬래브의 밑면이 경사진 캔티레바식 옹벽의 내진설계)

  • Kim, Hong Taek
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.10 no.3
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    • pp.87-98
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    • 1990
  • The present Study dealt with the earthquake-resistant design of cantilever retaining walls supporting cohesionless soils. With design examples of three different types of cantilever retaining walls, the factors of safety against sliding were computed at various values of horizontal acceleration coefficient and compared with each other. The horizontal inertia effect due to the weights of concrete wall itself and a portion of backfill was taken into account in the analyses, and also Mononobe-Okabe pseudo-static solution method was modified to deal with various states different from limiting equilibrium state. From the analyses of safety against sliding, it was found that a cantilever retaining wall with sloped base was the most efficient type in earthquake resistant design. It was also found that by sloping the base, the width of the base slab could be reduced, resulting in the least volume of concrete, excavation and backfill as compared to the other types of walls. In the case of a cantilever retaining wall with sloped feel, the efficiency similar to that of a wall with sloped base could be expected under static loading as well as at relatively low level of earthquake loading. However, this efficiency became vanished with the increase of horizontal acceleration coefficient, since the rate of reduction in developed earth pressures on the heel became smaller. In addition, the design charts with different soil friction angles as well as with different earthquake resistant design criteria of safety factor against sliding were presented for the design of cantilever retaining walls sith sloped base.

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Quality Characteristics of Bread Added with Black Sesame Powder (흑임자를 첨가한 식빵의 품질특성)

  • Choi, Soon-Nam;Chung, Nam-Yong
    • Korean journal of food and cookery science
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    • v.21 no.5
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    • pp.655-661
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    • 2005
  • This study was carried out to evaluate the effects of black sesame powder on bread quality. Breads were prepared by the addition of 0, 2.5, 5.0 and 7.5% of black sesame powder to the basic formulation. The weight of bread with black sesame powder ranged from 522.0 to 532.0 g and that of the control was 516.0 g. The volume of the bread prepared by adding 2.5, 5.0 and 7.5% black sesame powder was 2250.0, 2290.0, and 1800.0 mL, respectively. The water absorptive rate of bread with added black sesame powder decreased 3.83 to 2.48 and that of the control was 5.28. The lightness, redness and yellowness values of the bread decreased with the increase of black sesame powder. The hardness increased with the addition of black sesame powder, and was the highest for the bread with added 7.5 % black sesame powder. The sensory quality of the black sesame powder-bread as estimated by taste, and overall acceptability was better than that of the control product, and especially the quality of the bread with the addition of 2.5% black sesame powder was the best.