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A Comparison of Acute Effect of Air Stacking Using Resuscitator Bag versus Balloon on Pulmonary Functions (도수 소생기와 풍선을 이용한 공기 누적이 폐 기능에 미치는 즉각적인 효과 비교)

  • Ryu, Ji-Yun;Lee, Dong-Yeop;Hong, Ji-Heon;Kim, Jin-Seop;Kim, Seong-Gil
    • Journal of The Korean Society of Integrative Medicine
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    • v.9 no.1
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    • pp.23-31
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    • 2021
  • Purpose : To compare the immediate effects of air stacking maneuver using resuscitator bags and balloons. Methods : Twenty healthy young adults participated in this study. Forced vital capacity (FVC) and peak cough flow (PCF) tests were performed at pre-intervention, and then, the maximum insufflation capacity (MIC), forced expiratory volume in 1 s (FEV1), FEV1/FVC, peak expiratory flow (PEF), and peak cough flow (PCF) were measured using the air stacking maneuver via resuscitator bags and balloons. Interventions were randomly performed, and a 40-min break was provided between interventions. The evaluation process in this study was conducted in accordance with the guidelines of the American Thoracic Society (ATS) 2019. To compare the three outcomes measured at pre-and post-interventions, repeated measures analysis of variance was performed. Results : A significant difference was found in the MIC, FEV1, PEF, and PCF after the air stacking maneuver using resuscitator bags and balloons, whereas no significant difference was observed between resuscitator bags and balloons. Conclusion : No significant difference was found in the immediate effect of the air stacking maneuver using resuscitator bags and balloons in this study. Air stacking maneuver using balloons can increase the success rate of the techniques by providing visual feedback on the amount of air insufflation when performed with balloon blowing exercise. Balloons are cheaper and easier to buy compared to manual resuscitator bags; therefore, education on the air stacking maneuver using balloons will have a positive effect on pulmonary rehabilitation.

Study on Kidney Toxicities of WK-38 for Treatment Vascular Diseases in Rats (혈관질환 억제 효능이 있는 WK-38의 백서 신장 독성연구)

  • Kim, Eun-Ju;Lee, An-Sook;Shin, Sun;Kim, Sung-Yeon;Chang, Bo-Yoon;Lee, Ho-Sub;Kang, Dae-Gill
    • Herbal Formula Science
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    • v.17 no.2
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    • pp.187-194
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    • 2009
  • The kidney toxicities of WK-38 used for improvement of the vascular diseases, was examined using male and female Sprague-Dawley rats. The male and female rats were divided into 4 groups for intragastrical treatment with doses of 0, 5, 50, and 500 mg/kg/day for 13 weeks, respectively. In all male and female rats treated with WK-38, no mortality and gross pathological findings were shown for 13 weeks. There was substantially no change in body weight in all rats with treatment of WK-38. Urine osmolality as renal functional parameters were not exchanged in all rats treated with WK-38. The renal functional parameters including electrolytes excretory rate, creatinine clearance, and solute-free water reabsorption were significantly augmented on account of increase in urinary volume in female rats treated with WK-38, but not male. In summary, this study demonstrates that WK-38 exhibits no toxicity on kidney in all male and female rats.

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Anatase TiO2-doped activated carbon fibers prepared by ultrasonication and their capacitive deionization characteristics

  • Kang, Da Hee;Jo, Hanjoo;Jung, Min-Jung;Kim, Kyoung Hoon;Lee, Young-Seak
    • Carbon letters
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    • v.27
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    • pp.64-71
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    • 2018
  • $TiO_2$-doped activated carbon fibers (ACFs) were successfully prepared as capacitive deionization (CDI) electrode materials by facile ultrasonication-assisted process. ACFs were treated with titanium isopropoxide (TTIP) and isopropyl alcohol solutions of different concentrations and then calcinated by ultrasonication without heat-treatment. The results show that a certain amount of anatase $TiO_2$ was present on the ACF surface. The specific capacitance of the $TiO_2$-doped ACF electrode was remarkably improved (by 93.8% at scan rate of $50mV\;s^{-1}$) over that of the untreated ACF electrode, despite decreases in the specific surface area and total pore volume upon $TiO_2$ doping. From the CDI experiments, the salt adsorption capacity and charge efficiency of the sample with TTIP percent concentration of 15% were found to considerably increase by 71.9 and 57.1%, respectively. These increases are attributed to the improved wettability of the electrode, which increases the number of surface active sites and facilitates salt ion diffusion in the ACF pores. Additionally, the Ti-OH groups of $TiO_2$ act as electrosorption sites, which increases the electrosorption capacity.

Effects of Vitamin E Derivative TMG on the Radiation Protector and Tumor Growth during Radiotherapy

  • Yeun-Hwa Gu;Ryo Matsumoto;Takenori Yamashita
    • Journal of Radiation Protection and Research
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    • v.48 no.1
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    • pp.1-8
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    • 2023
  • Background: The purpose of this study is to evaluate the immunosuppressive and antioxidant effects of a novel radioprotective agent using the vitamin E derivative 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol (TMG) and its effect on tumors, and to study its usefulness. Materials and Methods: In this study, C57BL/6NCrSlc mice were divided into four groups (control, TMG, radiation therapy [RT], and RT+TMG), using 10 mice in each group. In the TMG and 2 Gy+TMG groups, 500 mg/kg TMG was administered. Two groups (2 Gy and 2 Gy+TMG) among RT and RT+TMG groups were irradiated with 2 Gy in a single fraction, while the other two groups (6 Gy and 6 Gy+TMG) were irradiated locally with 6 Gy in three fractions. Results and Discussion: TMG positively affected CD4+ and CD8+ T lymphocytes. Tumor volumes and growth inhibition rates were compared. In order to evaluate how TMG administration affected tumor growth, Ehrlich cancer cells were injected into the thigh of mice, and the tumor volume and growth suppression rate were compared. Not only RT but also TMG alone inhibited tumor growth. If RT conducted to the mice with TMG, TMG could increase the number of leukocytes, primarily that of lymphocytes. TMG also inhibited tumor growth in addition to RT. Tumor growth was significantly inhibited in the 6 Gy+TMG group. Conclusion: In conclusion, TMG exerted an immunopotentiating effect mainly by increasing the white blood cell numbers including that of lymphocytes. In addition to RT, TMG also inhibited tumor growth. Therefore, TMG is considered to be a useful radioprotective agent in radiotherapy without tumor growth induction.

Economics Approach on Validity of CNG Bus Promotion Policy (천연가스(CNG)버스 보급정책의 타당성 제고를 위한 연구)

  • Shin, Won Shik
    • Journal of the Korean Institute of Gas
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    • v.22 no.5
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    • pp.114-123
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    • 2018
  • As recognizing the necessity of eco-friendly vehicles in order to reduce air pollution from road sector, Korean government has established and implemented a promotion policy which is encouraging the public transportation companies to purchase CNG buses in replacing diesel buses since 2000s. With CNG bus promotion policy, the number of CNG buses had been increased on the road of metropolitan area and big cities. However, increasing rate of CNG buses had been fluctuated between the decrease and the increase since year 2014. In this study, the impact of fuel cost competitiveness between diesel and CNG on CNG bus increasing volume was testified by simple regression, which was only assumed by precedent research on the CNG promotion policy. And this study suggested the necessity of harmonization among the related policies conducted by related Ministries. Eventually this study should contribute to enhance the validity of CNG bus promotion policy. And it is expected that Korean government should apply the new policy suggestion of this study in the establishment of government's promotion policy on LNG cargo trucks and Zero Emission Vehicles in the future.

General Pharmacological Properties of the New +/K+ ATPase Inhibitor DBM-819

  • Park, Woo-Kyu;Kong, Jae-Yang;Kim, Hyun-Jung;Lee, Dong-Ha;Lim, Hong;Cheon, Hyae-Gyeong
    • Biomolecules & Therapeutics
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    • v.10 no.1
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    • pp.19-24
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    • 2002
  • The effects of a newly synthesized $H^+/K^+$ ATPase inhibitor,1-(2-methyl-4-methoxypheny)-4-[(3-hy-droxypropyl)amino] -6-methyl-2,3-dihydropyrrolo (3,2-c) quinoline (DBM-819) , on the central nervous system, isolated smooth muscle, cardiovascular and digestive systems and renal function were investigated in various experimental animals. Oral administration of DBM-819 had no effect on the central nervous system except body temperature of mice slightly decreased at doses of 15 and 50 mg/kg. DBM-819 produced a moderate analgesic effect in acetic acid-induced writhing test in mice at 50 mg/kg (p.o.). In conscious rats, DBM-819 (15 and 50 mg/kg, p.o.) showed a slight increase in blood pressure and a small decrease in heart rate. DBM-819 had an significant effect on agonist-induced contraction of guinea pig ileum at $1.5{\times}10^{-5}g/ml.$ No significant effect of DBM-819 (5 and 15 mg/kg, i.p) on urinary volume or urinary excretion of $Na^+,\;K^+$ and Cl- was observed in rats. DBM-819 had no significant effect on intestinal transport of a semisolid meal in mice at 15 and 50 mg/kg (p.o.). These findings suggest that DBM-819 exerts no significant pharmacological effects on the central nervous system and renal function at 15 mg/kg (p.o.), but produces some effects on the smooth muscle and circulatory system.

Advanced Treatment of Sewage Using Waste Plastic Vessel Media (폐플라스틱용기 미디어를 활용한 오수고도처리)

  • Kim, Jae-Yong;Um, Myeong-Heon;An, Dae-Hyun;Shim, Myeong-Jin
    • Applied Chemistry for Engineering
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    • v.17 no.1
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    • pp.58-61
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    • 2006
  • The object of this study was to develop an advanced method for fluid flow and oxygen transmission and increase adhesive property of microorganism to waste plastic vessel that was made of microorganism media. Through lab scale experiments, we found the optimum packed media volume rate and method, and when the optimum condition was applied to pilot plant, we confirmed possibility of advanced treatment. The sewage that was used in the test was the sewage disposal facility established in C and K elementary schools, which utilized waste plastic media oxidation engineering method. Analysis showed that removal efficiency of organic matter, SS, T-N and T-P was very high, that the sewage disposal facility maintained stability of treatment when changeable load of raw sewage flowed in.

The effect of soil heterogeneity and container length on the growth of Populus euramericana in a greenhouse study

  • Rahman, Afroja;Meng, Loth;Han, Si Ho;Seo, Gi Chun;Jung, Mun Ho;Park, Byung Bae
    • Korean Journal of Agricultural Science
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    • v.45 no.2
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    • pp.143-153
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    • 2018
  • Soil characteristics along with various container lengths have an important role in the early survival rate and growth of seedlings by influencing the seedling quality. This experiment was conducted to investigate the effect of container length and different soil mixtures on the growth of poplar in a greenhouse. Two types of soil, homogeneous vs. heterogeneous, were used along with two container lengths (30 vs. 60 cm). The heterogeneous soil was made by dividing 50% vermiculite from a mixture of 25% vermicompost and 25% nursery soil in volume. For the homogeneous soil, the above three soil types were mixed together. Populus euramericana clone cuttings were planted in late April, and then, the growth height, root collar diameter (RCD) and biomass were measured in August. The height of the poplar was not significantly affected by container length and soil type, but the RCD was significantly affected by soil type. Leaf and root biomass was higher at the long container than at the short container for both soil treatments, but stem biomass was lower at the heterogeneous soil than at the homogeneous soil treatment. Root to shoot biomass ratio was higher at the heterogeneous soil treatment than at the homogeneous soil treatment by 12%. In conclusion, heterogeneous soil along with a long container is suitable to increase the carbon allocation into the root.

Characteristics of Yellow Layer Cake Made with Mandarin Powder (밀감 분말을 첨가한 옐로우 레이어 케이크의 품질특성)

  • Park, Yeong-Sun;Shin, Sol;Shin, Gil-Man
    • Food Science and Preservation
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    • v.15 no.5
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    • pp.656-661
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    • 2008
  • basic formulation. Moisture content of 13.72%, crude protein 5.22%, crude lipid 1.31%, crud ash 1.94%, respectively. The pH of yellow layer cake decreased with increasing mandarin powder concentrations. In color values, with increase of mandarin powder concentration. The volume decreased with increasing mandarin powder concentration. The weights of yellow layer cake increased with increasing mandarin powder concentration. L value and a value decreased with increasing mandarin powder concentration in the crumb. b value increased with increasing mandarin powder concentration. The baking loss rate decreased with increasing mandarin powder. In the texture hardness, gumminess, chewiness and adhesiveness of yellow layer cakes significantly increased with increasing mandarin powder concentration. springiness and cohesiveness of yellow layer cakes significantly decreased. In the results of sensory evaluation, when compared to the control, the bread added to 9% of mandarin powder was superior to in color and flavor, while was similar to texture and taste.

Numerical Simulations of Diurnal Variations of Air Temperature and Relative Humidity in the Urban Canopy Layer (도시 캐노피 층 기온과 상대습도의 일변화에 관한 수치 모의)

  • Park, Kyeongjoo;Han, Beom-Soon;Jin, Han-Gyul
    • Atmosphere
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    • v.31 no.3
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    • pp.295-309
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    • 2021
  • Diurnal variations of air temperature and relative humidity in the Urban Canopy Layer (UCL) of the Seoul metropolitan area are examined using the Weather Research and Forecasting model coupled with the Seoul National University Urban Canopy Model. The canopy layer air temperature is higher than 2-m air temperature and exhibits a more rapid rise and an earlier peak in the daytime. These result from the multiple reflections of shortwave radiation and longwave radiation trapping due to the urban geometry. Because of the absence of vegetation in the UCL and the higher canopy layer air temperature, the canopy layer relative humidity is lower than 2-m relative humidity. Additional simulations with building height changes are conducted to examine the sensitivities of the canopy layer meteorological variables to the urban canyon aspect ratio. As the aspect ratio increases, net sensible heat flux entering the UCL increases (decreases) in the daytime (nighttime). However, the increase in the volume of the UCL reduces the magnitude of change rate of the canopy layer air temperature. As a result, the canopy layer air temperature generally decreases in the daytime and increases in the nighttime as the aspect ratio increases. The changes in the canopy layer relative humidity due to the aspect ratio change are largely determined by the canopy layer air temperature. As the aspect ratio increases, the canopy layer relative humidity is generally increased in the daytime and decreased in the nighttime, contrary to the canopy layer air temperature.