• Journal of Chest Surgery
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• 제29권1호
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• pp.1-6
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• 1996

5마리의 잡견(18~22kg)을 이용하여, 경막외강에 생리식염수를 연속 점적하여 뇌사를 유발시킨다. 뇌사발생시 점의 뇌압은 122.0$\pm$6.25mmHg이며 뇌사후 30분 최고치에 도달하였다. 뇌사를 유발시키는데 필요한 생리식염수의 양은 4.8$\pm$1.0ml이었고, 143.0$\pm$30.9분이 필요하였다. 뇌사가 올때까지 동맥압은 변하지 않지만 그후 점차 떨어지고, 맥박수는 뇌사 30분 후 안정시 보다 50% 정도 증가한 최고치에 달한다. 체온, 심박출량, 폐동맥압, 좌심실 이완말기압등의 혈역학적 지표는 뇌사진행 중에는큰 변화가 없었고, 심실 기외수축이 일시적으로 나타난 이외에는 부정맥도 관찰되지 않았다. 급작스러운 뇌압 상승 모델에서 보였던 혈역학적 변화는 관찰되지 않았다.

• 대한약리학회지
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• 제2권1호
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• pp.49-69
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• 1966

For the purpose of stydying the pharmacodynamic action of methemoglobin, the author made the following experiments: 1. Preparation of hemoglobin and methemoglobin solutions: Red cell suspension from rabbit blood was hemolysed with distilled water and then divided into two portions. One portion was dialysed through cellophane paper and made isotonic with the proper amount of sodium chloride. The second portion was treated with sodium nitrite to convert hemoglobin to methemoglobin, dialysed through cellophane paper and made isotonic. 2. The concentration of methemoglobin in solution, plasma and urine was determined by Horecker and Brackette's method, and that of hemoglobin by the cyanmethemoglobin method. 3. The concentration of methemoglobin and hemoglobin in the plasma and urine of rabbits was measured at several intervals of time after infusion of the above samples. 4. The blood pressure and respiration of rabbits were recorded on a kymograph, and the effects of the samples on them were observed. 5. The effects of the samples on the movements of the in-situ heart and the isolated intestine of rabbits were studied. 6. The kidneys of rabbits were excised 4 to 5 hours after injection of the samples, and histopathological examinations were made. These experiments revealed the following results: 1. When methemoglobin solution was allowed to stand in room air, there was no decrease in the concentration of methemoglobin. 2. When methemoglobin solution was mixed with whole blood and incubated at $37^{\circ}C$, the concentration of methemoglobin decteased gradually. 3. After the infusion of methemoglobin and hemoglobin solutions, the rate of disappearance of methemoglobin in the plasma was more rapid than that of hemoglobin in the plasma. The higher the initial concentration in the plasma, the larger was the rate of disappearance of methemoglobin. 4. The rate of disappearance of methemoglobin was exceedingly rapid for 30 minutes after the infusion. 5. The urinary excretion of methemoglobin was more rapid than that of hemoglobin. 6. It would seem that the circulating blood contains substances which are promptly mobilized in the plasma to reduce methemoglobin to hemoglobin. 7. Moderate amounts of methemoglobin solution caused some rise in the blood pressure and a transient acceleration of the respiration of the rabbits. These effects of methemoglobin were milder than those of hemoglobin. 8. The movements of the in-situ heart and the isolated intestine of rabbits were accelerated by methemoglobin. These accelerating effects were milder than those of hemoglobin. 9. In the kidneys of rabbits treated with methemoglobin solution, hyperemia of the glomeruli, cloudy swelling and hemoglobin deposit in the tubular epithelium, hemoglobin casts in the tubular lumina of the proximal tubules, and interstitial congestion were constantly observed. There was no definite difference between the histological findings in the rabbit kidneys injected with methemoglobin, and those injected with hemoglobin solutions.

• International Journal of Aeronautical and Space Sciences
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• 제16권3호
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• pp.418-424
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• 2015

The chemical response of energetic materials is analyzed in terms of 1) the thermal decomposition under the thermal stimulus and 2) the reactive flow upon the mechanical impact, both of which give rise to an exothermic thermal runaway or an explosion. The present study aims at building a set of chemical kinetics that can precisely model both thermal and impact initiation of a heavily aluminized cyclotrimethylene-trinitramine (RDX) which contains 35% of aluminum. For a thermal decomposition model, the differential scanning calorimetry (DSC) measurement is used together with the Friedman isoconversional method for defining the frequency factor and activation energy in the form of Arrhenius rate law that are extracted from the evolution of product mass fraction. As for modelling the impact response, a series of unconfined rate stick data are used to construct the size effect curve which represents the relationship between detonation velocity and inverse radius of the sample. For validation of the modeled results, a cook-off test and a pressure chamber test are used to compare the predicted chemical response of the aluminized RDX that is either thermally or mechanically loaded.

• 한국수소및신에너지학회논문집
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• 제23권3호
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• pp.227-235
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• 2012

Finding an alternative fuel and reducing environmental pollution are the main goals for future internal combustion engines. The purpose of this study is to obtain low-emission and high-efficiency by hydrogen enriched LPG fuel in constant volume chamber. An experimental study was carried out to obtain fundamental data for the combustion and emission characteristics of pre-mixed hydrogen and LPG in a constant volume chamber (CVC) with various fractions of hydrogen-LPG blends. To maintain equal heating value of fuel blend, the amount of LPG was decreased as hydrogen was gradually added. Exhaust emissions were measured using a HORIBA exhaust gas analyzer for various fractions of hydrogen-LPG blends. The results showed that the rapid combustion duration was shortened, and the rate of heat release elevated as the hydrogen fraction in the fuel blend was increased. Moreover, the maximum rate of pressure rise also increased. These phenomena were attributed to the burning velocity which increased exponentially with the increased hydrogen fraction in the $H_2$-LPG fuel blend. Exhaust HC and $CO_2$ concentrations decreased, while NOX emission increased with an increase in the hydrogen fraction in the fuel blend. Our results could facilitate the application of hydrogen and LPG as a fuel in the current fossil hydrocarbon-based economy and the strict emission regulations in internal combustion engines.

• 한국산학기술학회논문지
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• 제22권6호
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• pp.75-82
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• 2021

디젤엔진의 열효율을 높이면서 NOx와 PM을 효과적으로 저감시키기 위해 HCCI(Homogeneous Charge Compression Ignition), PCCI(Premixed Charge Compression Ignition), RCCI(Reactivity Controlled Compression Ignition) 등의 저온연소(LTC: Low Temperature Combustion)전략이 개발되어 왔다. 본 연구에서는 저반응성 연료로는 가솔린을 사용하고 고반응성 연료로는 디젤을 사용하는 RCCI 엔진에서 고반응성 연료인 디젤연료의 분사 시기와 이단 분사비율이 성능 및 배출가스에 미치는 영향을 수치해석을 통하여 파악하고자 하였다. 이단 분사 시 첫 번째 분사시기가 너무 진각되면 연소가 느려지면서 연소온도가 낮아져 연소성능이 저하되고 HC, CO가 증가한다. 대략 -60°ATDC 의 분사시기가 연소성능, 배출가스 및 최대압력상승률을 고려하였을 때 가장 최적의 분사시기라고 판단된다. 이단 분사 시 두 번째 분사시기를 변경하였을 때 연소성능 및 배출가스, 최대압력상승률 등을 고려하면 대략 -30°ATDC 부근에서 최적인 것으로 판단된다. 이단 분사 시 분사량 비율은 첫 번째 분사량을 60% 정도로 하였을 때 최적의 결과를 얻었다. 마지막으로 단일 분사보다는 이단 분사한 경우 연소성능 및 배출가스 부분에서 더 효과적인 것으로 판단된다.

• Journal of Nutrition and Health
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• 제16권3호
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• pp.209-215
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• 1983

본 연구는 성장기 아동의 뇨 중 sodium, potassium 및 creatinine 배설량과 혈압과 관련되는 제 요인간의 상관성을 조사하기 위하여 실시되었다. 12세부터 16세 사이의 성장기 아동 64명(남학생 41명, 여학생 23명)을 대상으로 하여 24시간 분의 뇨를 3회에 걸쳐 수집하였고 혈압과 맥박수를 측정하였으며 고혈압에 대한 가족력을 조사하였다. 그 결과를 요약하면 다음과 같다. 1) 체중 및 신장은 남학생이 $40.8{\pm}6.9kg$, $152.0{\pm}8.2cm$, 여학생이 $40.3{\pm}4.7kg$, $152.3{\pm}4.8cm$ 이었으며 한국소아발육표준치와 근사한 경향이었다. 상완위는 남학생이 $21.6{\pm}1.9cm$, 여학생이 $23.1{\pm}1.8cm$로 여학생이 남학생보다 유의하게$(p{\leqq}0.05)$높았다. 2) 수축기혈압은 남학생이 $102.3{\pm}12.8mmEg$, 여학생이 $95.5{\pm}10.7mmEg$이었고 확장기혈압은 남학생이 $49.7{\pm}9.6mmEg$, 여학생이 $58.2{\pm}10.1mmHg$로서 확장기혈압은 남학생이 유의있게 $(p{\leqq}0.05)$높았다. 3) 뇨 중 sodium 및 potassium 배설량은 남학생이 $132.8{\pm}45.4mEg/day$, $42.1{\pm}15.0mEg/day$이었고, 여학생이 $126.4{\pm}41.9mEg/day$, $41.3{\pm}13.9mEg/day$이었다. sodium 배설량으로부터 추정한 식염섭취량은 남녀 각각 9.1gm, 8.7gm 이었다. 뇨 중 creatinine 배설랑은 남학생이 $795.7{\pm}292.5mg/day$이었고 여학생이 $744.3{\pm}206.6mg/day$이었다. 4) 수축기혈압은 체중 $(p{\leqq}0.001,\;r=0.4735)$, 신장$(p{\leqq}0.001,\;r=0.4653)$ 및 creatinine 배설량$(p{\leqq}0.01,\;r=0.2726)$과 상관을 나타내었으며 sodium 배설량과는 상관을 보이지 않았다. 확장기혈압은 상완위$(p{\leqq}0.01,\;r=0.3135)$와 상관을 나타내었고 potassium 배설량 $(p{\leqq}0.05,\;r=-0.2594)$과는 부적 상관을 나타내었다. 5) 고혈압 가족력의 보유력은 28.1%이었으며 가족력 유 무집단 수축기혈압은 유의차를 보이지 않았으나 확장기 혈압이 유의있게$(p{\leqq}0.005)$높았다.

• Geomechanics and Engineering
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• 제21권5호
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• pp.433-445
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• 2020

The weakening and softening behavior of soft clay subjected to cyclic loading due to the build-up of excess pore water pressure is well-known. During the design stage of the foundation of highways and coastal high-rise buildings, it is important to study the mechanical behavior of marine soils under cyclic loading as they undergo greater settlement during cyclic loading than under static loading. Therefore, this research evaluates the cyclic stress-strain and shear strength of untreated and treated marine clay under the effects of wind, earthquake, and traffic loadings. A series of laboratory stress-controlled cyclic triaxial tests have been conducted on both untreated and treated marine clay using different effective confining pressures and a frequency of 0.5 and 1.0 Hz. In addition, treated samples were cured for 28 and 90 days and tested under a frequency of 2.0 Hz. The results revealed significant differences in the performance of treated marine clay samples than that of untreated samples under cyclic loading. The treated marine clay samples were able to stand up to 2000 loading cycles before failure, while untreated marine clay samples could not stand few loading cycles. The untreated marine clay displayed a higher permanent axial strain rate under cyclic loading than the treated clay due to the existence of new cementing compounds after the treatment with recycled tiles and low amount (2%) of cement. The effect of the effective confining pressure was found to be significant on untreated marine clay while its effect was not crucial for the treated samples cured for 90 days. Treated samples cured for 90 days performed better under cyclic loading than the ones cured for 28 days and this is due to the higher amount of cementitious compounds formed with time. The highest deformation was found at 0.5 Hz, which cannot be considered as a critical frequency since smaller frequencies were not used. Therefore, it is recommended to consider testing the treated marine clay using smaller frequencies than 0.5 Hz.

• 한국추진공학회지
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• 제19권1호
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• pp.61-67
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• 2015

연소기 시험 장치의 구축 시 고온의 연소 가스의 냉각은 중요한 설계요구조건이다. 물 분무(Water spray) 냉각 방식은 증발 과정에서 물의 잠열을 이용하므로, 효과적인 연소 가스 냉각이 가능하다. 본 연구에서는 연소기 시험 설비 구축 과정의 일환으로, 물 분무를 이용한 연소 가스의 냉각을 이해하기 위하여 연속방정식, 에너지 보존식과 포화 증기의 압력-온도 관계식을 이용한 1차원 해석을 수행하였다. 연소기 시험 장치에서 배출되는 고온, 고압의 연소 가스는 냉각수와의 혼합과정에서 배출가스의 온도가 낮아지며, 분무된 물의 일부는 기화하여 연소가스와 함께 배출되고, 일부는 다시 응축 되어 집수조로 모인다. 냉각수는 연소 가스의 온도를 낮춰주는 동시에, 증발된 증기는 연소기 내부의 압력을 증가시키므로 1차원 해석에서 증기의 압력-온도 관계식을 고려하여 해석을 수행하였다. 1차원 해석으로부터 연소가스의 적절한 냉각과 배기 덕트 내부의 압력의 지나친 상승을 피하기 위한 최적의 물 분무량을 확인하였으며, 물 분무 냉각 방식에 대한 물리적 이해를 얻을 수 있었다.

• 한국지반공학회논문집
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• 제18권6호
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• pp.5-16
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• 2002

사면 내의 지하수 유동과 사면의 안정성에 대한 강수의 영향을 평가하기 위하여 수리지질역학적 수치 모델이 제시되었다. 이 수치 모델은 변형성 지질매체 내에서의 포화-불포화 지하수 유동을 설명하는 완전 연동된 간극탄성론적 지배 방정식들과 Galerkin 유한요소법에 근거하여 개발되었다. 이렇게 개발된 완전 연동된 수리지질역학적 수치 모델은 다양한 강수량 조건 하에 있는 불포화 사면에 대한 일련의 수치모의실험에 적용되었다. 이러한 수치모의실험 결과들은 강수량이 증가할수록 사면의 전반적인 수리역학적 안정성이 저하되며 잠재적인 파괴가 사면 전단부에서부터 시작되어 사면 정상부 쪽으로 팽창됨을 보여주고 있다. 강수량이 증가함에 따라 수리지질학적으로는 압력수두와 전체 수리수두가 증가한다. 그 결과 지하수면이 상승하고 불포화대가 감소하며 삼출면이 사면 전단부로부터 사면 정상부쪽으로 팽창하고 이러한 삼출면에서의 지하수 유동 속도도 증가하게 된다. 한편 강수량이 증가함에 따라 지질역학적으로는 사면 전단부를 향해 수평 변위는 증가하지만 수직 변위는 감소하게 된다. 이는 강수량 증가에 따른 지하수면의 상승에 수반하는 부력에 기인하는 것으로 해석된다. 그 결과 사면의 전반적인 변형이 사면 전단부를 향해 심화되고 전단파괴 안전율이 1 이하인 불안전한 지역이 사면 전단부에서 두꺼워지면서 사면 전단부에서부터 사면 정상부 쪽으로 팽창하게 된다. 또한 수치모의실험 결과들은 이러한 잠재적인 전단파괴면과 지표면 사이의 지반에서는 잠재적인 인장파괴가 발생할 수 있음을 보여주고 있다.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2005년도 춘계 학술대회논문집
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• pp.25-29
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• 2005

Axial fan is used for the supplement of large amount of flows. Axial blowers show relatively high efficiency of the system. The present model of axial fan is for cooling a condenser in an air-conditioning unit that exhibits tendency toward compact size. In order to realize the compact model, the width of an axial blade should be cut down in axial distance. Main interest lies on the performance of the axial blowing system with blades having shorter chord length. One of the important design parameters for axial fan is the shape of the blades of it. Design of blades includes the cross-sectional shape and its dimension, including the chord length. We consider two types of blades; one is NACA airfoil with normal chord length and the other is with shortening chord length by $10\%$ of normal airfoil. Axial blower with the modified blades is essential for the compact model of an air-conditioner. The other design parameters are same in the two cases. Using a wind tunnel follows ASHRAE standards carries out evaluation of performance of the system. Detail of flows around the blades is prepared by velocity measurements using PIV. According to performance estimation, the axial blower with short chord blade show quite close to the performance results, including flow rate and pressure rise, of the standard one. The reason of the two similar results is that the flowpatterns depend on Reynolds number based on the chord length of a blade. In this investigation, the critical chord length is found, in which the flows near the airfoil are so unstable and the performance of the system is decreased. A series of figures is for the detail information on the flow.