• Title/Summary/Keyword: Rate Effect

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Dissolution Rates of Indomethacin Preparations (Indomethacin 제제(製劑)의 용출(溶出)에 관한 연구(硏究))

  • Paik, W.S.;Kim, H.J.;Kim, K.S.;Lee, H.B.
    • Journal of Pharmaceutical Investigation
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    • v.13 no.3
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    • pp.104-109
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    • 1983
  • The effect of diluents on the dissolution rate of indomethacin was studied and the dissolution rate for the marketed products was compared to establish the quality standard for indomethacin preparation. The results are as fellows 1. The effect of test methods was not significant in the case of paddle method but was greatly effected in the case of basket method. 2. The effect of diluents was not significant generally, but in the case of starch dissolution rate was greatly effected. 3. The dissolution rate was remarkably decreased in proprotion to increase of capsule size. 4. The marketed products met the KP dissolution requirement but showed a little difference due to manufacturers.

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The Noise Effect on Stuttering and Overall Speech Rate: Multi-talker Babble Noise (다화자잡음이 말더듬의 비율과 말속도에 미치는 영향)

  • Park, Jin;Chung, In-Kie
    • Phonetics and Speech Sciences
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    • v.4 no.2
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    • pp.121-126
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    • 2012
  • This study deals with how stuttering changes in its frequency in a situation where adult participants who stutter are exposed to one type of background noise, that is, multi-talker babble noise. Eight American English-speaking adults who stutter participated in this study. Each of the subjects read aloud sentences under each of three speaking conditions (i.e., typical solo reading (TSR), typical choral reading (TCR), and multi-talker babble noise reading (BNR)). Speech fluency was computed based on a percentage of syllables stuttered (%SS) and speaking rate was also assessed to examine if there was significant change in rates as a measure of vocal change under each of the speaking conditions. The study found that participants read more fluently both during BNR and during TCR than during TSR. The study also found that participants did not show significant changes in speaking rate across the three speaking conditions. Some discussion was provided in relation to the effect of multi-talker babble noise on the frequency of stuttering and its further speculation.

The Effect of DSC Analysis Condition on the Glass Transition Temperature of curred Epoxy This paper studies on the effect of DSC(Differential Scanning Calorimeter) analysis condition on the glass transition temperature of silica filled epoxy network polymer used for ultra-high voltage apparatus. The effects of temperature scanning rate specimen size and gas flow rate on measured glass transition temperature have been studied in order to select optimum thermal analysis condition. (에폭시 경화물 DSC에 의한 유리전이 온도 측정의 분석조건 의존성)

  • 오무원;권혁삼
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1994.05a
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    • pp.30-33
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    • 1994
  • This paper studies on the effect of DSC(Differential Scanning Calorimeter) analysis condition on the glass transition temperature of silica filled epoxy network polymer used for ultra-high voltage apparatus. The effects of temperature scanning rate specimen size and gas flow rate on measured glass transition temperature have been studied in order to select optimum thermal analysis condition.

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Coolant Effect on Gas Generator Propellant (가스발생기용 추진제에 대한 냉각제 효과)

  • Baek Gookhyun;Yim Yoo-Jin
    • Journal of the Korean Society of Propulsion Engineers
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    • v.9 no.2
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    • pp.1-8
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    • 2005
  • The effect of coolants has been studied on the burning properties of low burning rate HTPB/AP composite propellant containing Oxamide or Melamine as coolant for the gas generator. With increasing the content of coolant, the burning rate and the flame temperature could be lowered and the effect on flame temperature was about the same for two coolants. However due to the different thermal decomposition properties of coolant, the burning rate of Melamine propellant was found to abnormally decrease if $200{\mu}m$ AP was partially replaced with $6{\mu}m$ AP.

An inverse determination method for strain rate and temperature dependent constitutive model of elastoplastic materials

  • Li, Xin;Zhang, Chao;Wu, Zhangming
    • Structural Engineering and Mechanics
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    • v.80 no.5
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    • pp.539-551
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    • 2021
  • With the continuous increase of computational capacity, more and more complex nonlinear elastoplastic constitutive models were developed to study the mechanical behavior of elastoplastic materials. These constitutive models generally contain a large amount of physical and phenomenological parameters, which often require a large amount of computational costs to determine. In this paper, an inverse parameter determination method is proposed to identify the constitutive parameters of elastoplastic materials, with the consideration of both strain rate effect and temperature effect. To carry out an efficient design, a hybrid optimization algorithm that combines the genetic algorithm and the Nelder-Mead simplex algorithm is proposed and developed. The proposed inverse method was employed to determine the parameters for an elasto-viscoplastic constitutive model and Johnson-cook model, which demonstrates the capability of this method in considering strain rate and temperature effect, simultaneously. This hybrid optimization algorithm shows a better accuracy and efficiency than using a single algorithm. Finally, the predictability analysis using partial experimental data is completed to further demonstrate the feasibility of the proposed method.

Effect of W Addition on the Hardenability of Low-Carbon Boron Steels (저탄소 보론강의 경화능에 미치는 W 첨가의 영향)

  • Hwang, Byoungchul
    • Korean Journal of Materials Research
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    • v.24 no.9
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    • pp.488-494
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    • 2014
  • The effect of tungsten (W) addition on the hardenability of low-carbon boron steels was investigated using dilatometry, microstructural observations and secondary ion mass spectroscopy. The hardenability was discussed with respect to transformation behaviour aspects depending on the segregation and precipitation of boron at austenite grain boundaries. A critical cooling rate producing a hardness corresponding to 90 % martensite structure was measured from a hardness distribution plot, and was used as a criterion to estimate hardenability at faster cooling rates. In the low-carbon boron steel, the addition of 0.50 wt.% W was comparable to that of 0.20 wt.% molybdenum in terms of critical cooling rate, indicating hardenability at faster cooling rates. However, the addition of 0.50 wt.% W was not more effective than the addition of .0.20 wt.% molybdenum at slower cooling rates. The addition of 0.20 wt.% molybdenum completely suppressed the formation of eutectoid ferrite even at the slow cooling rate of $0.2^{\circ}C/s$, while the addition of 0.50 wt.% W did not, even at the cooling rate of $1.0^{\circ}C/s$. Therefore, it was found that the effect of alloying elements on the hardenability of low-carbon boron steels can be differently evaluated according to cooling rate.

Effects of Finite-Rate Chemistry and Film Cooling on Linear Combustion-Stability Limit in Liquid Rocket Engine (액체 로켓엔진에서 선형 연소 안정한계에 미치는 유한화학반응 및 막냉각 효과)

  • Sohn Chae Hoon;Park I-Sun;Moon Yoon Wan;Kim Hong-Jip;Oh Hwa Young;Huh Hwanil
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • v.y2005m4
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    • pp.189-193
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    • 2005
  • Thermal effect of finite-rate chemistry on linear combustion stability and film cooling effect are investigated in sample rocket engine. The flow variables required to evaluate stability limits are obtained from CFD data with finite-rate chemistry adopted in three dimensional chamber. Major flow variables are affected appreciably by finite-rate chemistry and thereby, the calculated stability limits are modified. It is found that finite-rate chemistry contributes to stability enhancement in thermal point of view. And film cooling also has the effect of combustion stabilization.

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Anthelminthic Effect of Oxantel Pamoate against Trichocephalus trichiurus Infection (Oxantel pamoate의 편충(鞭虫)에 대한 구충효과(驅虫效果))

  • Lim, J.K.
    • The Korean Journal of Pharmacology
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    • v.10 no.2
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    • pp.25-29
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    • 1974
  • The present clinical trial was performed to evaluate the anthelminthic effect and tolerance of Oxantel pamoate, a new antiwhipworm agent, in the treatment of T. trichiurus infection. Oxantel pamoate oral suspension was administered as a sing1e dose of 10 mg per kg. body weight to a total of 46 T. trichiurus infected cases selected out of 64 positives, by examining 89 fecal specimens collected from the soldiers and in-patients of xx Armed Forces General Hospital. For the evaluation, the negative conversion rate (cure rate) and the egg reduction rate were assessed 22 days after the treatment. The result obtained were as follows: 1. The prevalence rate of T. trichiurus infection in this study was 71.9%, while the mean E.P.G. of 46 treated cases was 126. 2. The egg negative conversion rate was 91.3%, and 98.4% of egg reduction rate was obtained. 3. From the observation of 107 worms expelled during 3 consecutive days after the treatment, it was known that sex ratio of male and female was about 1 : 2 and that average worm burden per capita was 2.3. 4. In all treated cases, the medication was readily accepted and well tolerated. On the hemograms, urinalysis and liver function tests, no significant differences were noted before and after the drug administration. There was also no detectable objective and subjective side effect.

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Effect of Process Parameters on the Hardness and Wear Rate of Thermal Sprayed Ni-based Coatings (니켈기 경질 용사코팅의 경도 및 마모율에 미치는 공정조건의 영향)

  • Kim, K.T.;Kim, J.D.;Kim, Y.S.
    • Journal of Power System Engineering
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    • v.15 no.1
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    • pp.51-56
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    • 2011
  • The various process parameters of thermal spray process affects on quality of Ni-based coatings. Thus, there is need to analyze the effect of process parameters on quality of Ni-based coatings. In this paper, the effects of process parameters on hardness and wear rate of Ni-based coatings were investigated using 4 design of experiments. First, the Ni-based coatings were fabricated according to $L_9(3^4)$ orthogonal array. The hardness tests and the wear tests were performed on the Ni-based coatings. The analysis of variance for the hardness and wear rate were carried out. As a results, the acetylene gas flow and the powder feed rate were identified as main factors effected on the hardness and the oxygen gas flow and the acetylene gas flow were identified as main factors effected on the wear rate. The full factorial experiments design with different levels was applied for investigation of effect of these main factors.

Proposed Operating Parameters for Advanced Treatment Process using a Cilium Media BNR Process (섬모상담체를 이용한 고도처리공정의 운전인자 도출)

  • Ahn, Yoon Hee;Park, Chan Gyu;Ko, Kwang Baik;Lee, Kang Soo
    • Journal of Korean Society on Water Environment
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    • v.23 no.5
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    • pp.761-765
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    • 2007
  • The study were conducted in order to investigate the effect of operating parameters including the internal recycle (nitrification return) rates, hydraulic retention times (HRTs) and temperature when using a cilium media method. The first experiment was for evaluating the effect of HRT (12 hr, 10 hr, 8 hr, 6 hr, 4 hr). The second experiment was for analyzing effect of internal recycle rate (100%, 200%, 300%, 400%). As a result of the first experiment, BOD was removed to 97~98% for 6~8 hr HRT. Effluent water quality was not significantly influenced with HRT within that range. However the nitrogen removal was sensitive to HRT. T-P removal efficiency was invariable at various HRTs. The average BOD removal efficiency was about 97% in spite of change of internal recycle rate while T-N removal efficiency was increased at the internal recycle rate of 100~200%, but invariable at the internal recycle rate of 200~300%.