• International Journal of Aeronautical and Space Sciences
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• v.17 no.1
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• pp.20-28
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• 2016

In this study, an efficient method of designing laminate composite radar absorbing structures (RAS) is proposed with consideration given to the structural shape so as to improve aircraft stealth performance. The calculation of the radar cross section (RCS) should be decreased to enhance the efficiency of the stochastic optimization when designing an RAS. In the proposed method, RAS are optimized to match up the input impedance of the minimal RCS, which is obtained by using physical optics and the transmission line theory. Single and double layer dielectric RAS for aircraft wings are employed as numerical examples and designed using the proposed method, RCS minimization and reflection coefficient minimization. The availability of the proposed method is assessed by comparing the similarity of the results and computation time with other design methods. According to the results, the proposed method produces the same results as the stochastic optimization, which adopts the RCS as the objective function, and can improve RAS design efficiency by reducing the number of RCS analyses.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.05b
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• pp.1164-1168
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• 2005

최근에 홍수범람도나 재해지도를 작성하는 등 하천에 대한 범람해석의 연구가 활발히 진행되고 있는 실정이다. 1차원 하천범람해석은 홍수위를 산정하고 지리정보시스템을 이용하여 범람구역을 작성하는 경우가 일반적으로 적용되고 있다. 본 연구에서는 ArcView를 이용하여 광양항 유역특성에 대해 조사하고 홍수범람을 예측하기 위해 HEC-GeoRAS 및 HEC-RAS를 이용하여 홍수범람지역 및 수리특성을 분석하였다. 광양항 지역특성인 조석 및 다수의 유입지류가 존재하는 조건을 고려하기 위해 HEC-RAS 부정류 모의을 이용하여 수위를 분석하였다. 또한 기존 수치지도와 현 상태를 재측량한 성과를 합성하여 지형자료를 추출하여 지형적 오차를 방지하였다. 본 연구에서 1차원 하천 부정류 모의 결과는 각 측점에 대해 시간대별로 수리특성을 계산하였으며 최대수위는 EL. 3.05m로 산정되었다. 또한 유속과 유량이 음(-)의 값을 갖는 경우에 흐름 방향이 역전되므로, 측점 4040.969에서 흐름이 분기되는 것으로 판단되었다. 또한 대상구간에 대한 홍수범람해석을 HEC-GeoRAS 후처리과정을 이용하여 각 측점에 따라 시간별대로 산정하였다. 일부 하천구간 및 저지대의 경우에 침수되는 것으로 표시되었으며, 이것은 1차원 범람해석상의 한계로 판단되었다.

• Journal of The Korean Society of Agricultural Engineers
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• v.54 no.2
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• pp.87-94
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• 2012

This study is to evaluate flood inundation and to recommend measures of damage reduction on sediment by concentrated torrential rainfall at Gonjiamcheon Watershed (183.4 $km^2$). Firstly, the SWAT (Soil and Water Assessment Tool) was simulated streamflow and sediment at upstream. Then, we produced a map of floodplain boundary by using HEC-RAS (Hydrologic Engineering Centers River Analysis System) at downstream. The SWAT model was calibrated with 2 years (2008~2009) daily streamflow and validated for another years (2010~2011. 7. 31). The SWAT model was simulated with 3 years (2008~2010) by monthly water quality (Sediment) at Gonjiamcheon water quality station. The streamflow and sediment from SWAT model were input as boundary conditions to HEC-RAS. The results of HEC-RAS indicated that mapping of floodplain boundary was Jiwol and Jiwol 2 district. Additionally, inundation area and depth were assessed and applied BMPs scenario for managing the sediment yield.

• Journal of the Korean Society of Food Science and Nutrition
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• v.21 no.3
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• pp.314-318
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• 1992

The sarcoma 180 cells were treated with ursolic acid which was previously extracted from leaves of Eriobotrya japonica Lindy (Rosaceae) and identified as a potent anticarinogenic agent. Suppressing effects of the compounds with testing changes in selected oncogenes expression were examined by using the northern hybridization method. Ursolic acid significantly suppressed c-myc oncogene expression. However, c-ha-ras oncogene expression was lowered slightly with the ursolic acid treatment. Therefore, it was concluded that preproven anticarcinogenic effects of ursolic acid should be partly ascribed to the modified oncogenic expression.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2003.04a
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• pp.139-142
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• 2003

As composite materials are gaining wide acceptance in aircraft structure, repair of damaged composite is becoming an important issue. The issues in composite repair include high cost, material interchangeability, water ingression, and structural integrity. To address these problems, researchers have studied on the composite repair in various aspects. In this paper, an Internet-based advisory service (called Repair Advisory Service, RAS) for composite repair is proposed to increase efficiency for repair process. In the RAS system the web browser is used as its user interface, which provides easy access to the service. The RAS server provides web-based tools for failure prediction, Structural Repair Manual (SRM), automated prepreg cutting process, material properties, inventory and knowledge base. The computer codes implemented for repair design estimate the tensile failure and shear failure of repaired structures. The prediction of failure is based on the maximum strain criterion for tensile failure while elastic-perfect plastic shear failure model is applied for interfacial failure. The OEM's SRM is provided in the PDF format for viewing and searching by web browsers instead of looking up paper version SRM. The knowledge base in this site offers a room to share and distribute ideas, memos, publications, or suggestions from the repair engineers. The fabrication tool of RAS reads repair geometry from engineers then generates a CNC toolpath to cut prepreg patches. The RAS service is open to public and available at http://nano.gsnu.ac.kr/. Broad feedback from field technicians and engineers is welcome to improve the usefulness of RAS.

• Korean Journal of Clinical Pharmacy
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• v.29 no.4
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• pp.247-253
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• 2019

Background: Glutamate is implicated in the pathophysiology of migraine, a common neurological disorder. Therefore, glutamate receptor antagonists (GluRAs) have been suggested as a novel migraine treatment that are able to overcome the limitations of triptans. Objective: The aim of this study was to perform a meta-analysis to assess the efficacy of GluRAs for patients with migraine. Method: The PubMed, Cochrane Library, CINAHL, and Clinical Trial.gov databases were searched for randomized placebo-controlled trials of the efficacy of GluRAs for patients with migraine conducted up to August 2019. Two independent reviewers screened the literature according to inclusion and exclusion criteria and performed quality assessment and data extraction. Review Manager 5.3 software was used for the meta-analysis. Results: Three studies involving a total of 206 patients were included in the final analysis. Compared with placebo, GluRAs significantly improved the pain-free response at 2 hours (odds ratio [OR]=3.85, 95% confidence intervals [CIs]=1.63-9.09) and the 24-hour sustained pain freedom (OR=7.40; 95% CIs=2.36-23.20). The use of rescue medications with GluRAs was lower compared to that with placebo, but the difference was not significant (OR=0.39, 95% CI=0.10-1.47). Conclusion: Our meta-analysis showed that GluRAs were more effective than placebo for patients with migraine.

• Archives of Pharmacal Research
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• v.24 no.4
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• pp.349-354
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• 2001

Curcumin, a dietary pigment in turmeric, posseses anti-carcinogenic and anti-metastatic properties. The present study was conducted to study in vitro chemopreventive effects of curcumin in transformed breast cells. Here, we show that curcumin inhibits H-ras-induced invasive phenotype in MCF10A human breast epithelial cells (H-ras MCF10A) and downregulates matrix metalloproteinase (MMP)-2 dose-dependently. Curcumin exerted cytotoxic effect on H-ras MCF10A cells in a concentration-dependent manner. Curcumin-induced cell death was mainly due to apoptosis in which a prominent downregulation of Bcl-2 and upregulation of Bax were involved. We also suggest a possible involvement of caspase-3 in curcumin-induced apoptosis. Curcumin treatment resulted in the production of reactive oxygen species (ROS) in H-ras MCF10A cells. Apoptotic event by curcumin was significantly inhibited by pretreatment of an antioxidant N-acetyl-$_L$-cysteine (NAC), suggesting redox signaling as a mechanism responsible for curcumin-induced apoptosis in H-ras MCF10A cells. Taken together, our results demonstrate that curcumin inhibits invasion and induces apoptosis, proving the chemopreventive potential of curcumin .

• Membrane and Water Treatment
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• v.9 no.2
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• pp.123-128
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• 2018

Common aquaculture practices include the use of certain pharmaceuticals such as antibiotics in avoiding diseases and promoting a healthier growth of the culture. The aim of this study is to monitor and assess the influence of different low oxytetracycline concentrations on the transformation of nitrogen compounds under aeration condition in a lab-scale recirculating aquaculture system (RAS). Over $1mg\;L^{-1}$ dose of oxytetracycline to aquaculture had induced ammonia($NH_4-N$), nitrate($NO_3-N$), soluble COD accumulation in RAS. In addition, nitrous oxide ($N_2O$) emission from RAS was significantly reduced during the oxytetracycline dose periods. After ceasing the dose of oxytetracycline, ammonia oxidation and nitrous oxide re-emission were observed. This observation indicated that low concentrations of oxytetracycline could affect the nitrogen species in RAS. Also, the emission mechanisms of $N_2O$ may not be only dependent on nitrification process but also dependent on denitrification process in our RAS system.

• Journal of Industrial and Engineering Chemistry
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• v.68
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• pp.109-116
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• 2018

$Eu_2(SO_4)_3$ was synthesized by chemical precipitation method and the crystal structure was determined by Rietveld analysis. The compound crystallizes in monoclinic space group C2/c. In the air environment, $Eu_2(SO_4)_3$ is stable up to $670^{\circ}C$. The sample of $Eu_2(SO_4)_3$ was examined by Raman, Fourier-transform infrared absorption and luminescence spectroscopy methods. The low site symmetry of $SO_4$ tetrahedra results in the appearance of the IR inactive ${\nu}_1$ mode around $1000cm^{-1}$ and ${\nu}_2$ modes below $500cm^{-1}$. The band intensities redistribution in the luminescent spectra of $Eu^{3+}$ ions is analyzed in terms of the peculiarities of its local environment.

• Nuclear Engineering and Technology
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• v.51 no.4
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• pp.1163-1168
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• 2019

Hydrodynamic properties have been investigated for promising extraction systems: $0.05mol\;L^{-1}$ solutions of di(N-ethyl-4-ethylanilide) of 2,2'-bipyridine-6,6'-dicarboxylic acid, di(N-ethyl-4-fluoroanilide) of 2,6-pyridinedicarboxylic acid and di(N-ethyl-4-hexylanilide) of 2,2'-bipyridine-6,6'-dicarboxylic acid in meta-nitrobenzotrifluoride (F-3) or trifluoromethylphenyl sulfone (FS-13) diluents. To evaluate the perspectives for their use as extraction mixtures at the final stage of the nuclear fuel cycle, the change in density, viscosity, surface tension, and phase separation rate under irradiation with accelerated electrons was studied. The concentrations of extractants in the irradiated mixtures have been determined and the radiation-chemical yields have been calculated. Irradiation significantly decreases the phase separation rate at the stages of extraction and back extraction for all the studied systems. The viscosity of the DYP-7 solution in FS-13 increase above the values suitable for its use in extraction processes.