• 한국철도학회:학술대회논문집
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• 한국철도학회 2005년도 춘계학술대회 논문집
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• pp.909-914
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• 2005

본 논문에서는 PRT (Personal Rapid Transit)의 원격 제어를 위한 무선 채널 환경에서 안테나 선택 기법을 적용한 MIMO-OFDM 시스템에서 귀환 정보의 양을 줄이는 효과적인 기법을 제안한다. 제안한 기법은 PRT 무선 채널 환경에서 차량에 할당된 주파수 채널 상관도에 따라 부반송파들을 그룹 단위로 나눈 후 그룹의 중앙에 위치한 부반송파의 채널 값을 기준으로 해당 부반송파 그룹의 송신 안테나를 선택한다. 모의실험을 통해 해당 그룹의 부반송파들의 수를 적절히 선택하면 적은 성능의 열화를 가지고도 귀환 정보의 양을 크게 줄일 수 있음을 확인하였다. 특히 PRT 무선 채널 환경에서 차량과 제어기지국 사이의 귀환 채널의 전송률이 고정된 경우, 차량의 속도가 증가할수록 제안한 기법이 더욱 좋은 성능을 보였다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제18권2호
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• pp.89-95
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• 2018

Background: Incorrect administration of an anesthetic during local anesthesia is one of the most important causes of pain symptoms in patients scheduled for dental procedures. The current study assessed the severity of damage to periodontal tissue following different rates of anesthetic administration. Methods: The research was conducted on 50 outbred male rats with a body mass of 180-240 g. The anesthetic used was 1% articaine. Results: The results showed that administration of the anesthetic at a rapid pace caused structural damage to the periodontal tissue. Further, signs of impaired microcirculation were noted at all rates of administration. Biochemical studies demonstrated changes in the level of glucose and enzymes with the rapid introduction of the anesthetic, indicating severe systemic stress response of the body. Conclusions: Injection of local anesthetic at any rate of introduction induces vascular congestion in the microcirculatory bloodstream and exudative reactions. Rapid introduction of an anesthetic causes progression of structural changes in the gingival tissue.

• 센서학회지
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• 제14권5호
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• pp.337-342
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• 2005

A silicon-based micro-reactor to amplify small amount of deoxyribonucleic acid (DNA) has been fabricated using micro-electro-mechanical systems (MEMS) technology. Polymerase chain reaction (PCR) of DNA requires a precise and rapid temperature control. A Pt sensor is integrated directly in the chamber for real-time temperature measurement and an infrared lamp is used as external heating source for non-contact and rapid heating. In addition to the real-time temperature sensing, PCR needs a rapid thermocycling for effective PCR. For a fast thermal response, the thermal mass of the reactor chamber is minimized by removal of bulk silicon volume around the reactor using double-side KOH etching. The transparent optical property of silicon in the infrared wavelength range provides an efficient absorption of thermal energy into the reacting sample without being absorbed by silicon reactor chamber. It is confirmed that the fabricated micro-reactor could be heated up in less than 30 sec to the denaturation temperature by the external infrared lamp and cooled down in 30 sec to the annealing temperature by passive cooling.

• Carbon letters
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• 제12권1호
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• pp.21-25
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• 2011

A novel electrode for an NO gas sensor was fabricated from electrospun polyacrylonitrile fibers by thermal treatment to obtain carbon fibers followed by chemical activation to enhance the activity of gas adsorption sites. The activation process improved the porous structure, increasing the specific surface area and allowing for efficient gas adsorption. The gas sensing ability and response time were improved by the increased surface area and micropore fraction. High performance gas sensing was then demonstrated by following a proposed mechanism based on the activation effects. Initially, the pore structure developed by activation significantly increased the amount of adsorbed gas, as shown by the high sensitivity of the gas sensor. Additionally, the increased micropore fraction enabled a rapid sensor response time due to improve the adsorption speed. Overall, the sensitivity for NO gas was improved approximately six-fold, and the response time was reduced by approximately 83% due to the effects of chemical activation.

• 대한의생명과학회지
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• 제11권2호
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• pp.249-252
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• 2005

The mammalian unfolded protein response (UPR) protects the cell. against the stress of unfolded or misfolded proteins in the endoplasmic reticulum (ER). It has recently demonstrated that IRE1, PERK, ATF6, and X-box protein 1 (XBP-l) directly or indirectly participate in this process. Upon accumulation of unfolded/misfolded proteins in the ER lumen, release of BiP from Ire1p permits dimerization and autophosphorylation to activate its kinase and endoribonulease activities to initiate XBP-1 mRNA splicing. Spliced XBP-1 mRNA removed middle part of 23 bp and encodes a potent transcription factor, XBP-l protein that binds to the unfolded protein response element (UPRE) or endoplasmic reticulum stress element (ERSE) sequence of many UPR target genes and produces several kind of ER chaperones. In this study, we described both the result and the detailed experimental procedures of XBP-1 mRNA splicing induced by ER stress, this result might help to elucidate the roles of the UPR and early diagnosis in a number of human diseases involving endoplasmic reticulum storage disease (ERSD).

• Journal of Power Electronics
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• 제16권3호
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• pp.1076-1086
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• 2016

PI controllers are one of the most widely used controllers in industrial control systems due to their simple algorithms and stability. The parameters K_p and K_i determine the performance of the system response. The response is expected to improve by increasing the gain of the PI controller. However, too large a gain will accelerate the speed response and cause vibrations, which is not what is expected. This paper proposes a way to suppress vibrations by detecting the vibration frequency and extracting the vibration signal as a compensation to the speed feedback. Additionally, in order to improve its disturbance rejection ability, a low-order disturbance observer is proposed. This paper also explains the operation principle of the proposed method by analyzing the transfer function and it describes the design of the controller parameters in detail. Simulation and experimental results are provided to verify the merits of the proposed method. These results also show the good performance of the proposed method. It has a rapid response and suppresses vibrations.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 Techno-Fair 및 추계학술대회 논문집 전기물성,응용부문
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• pp.86-87
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• 2007

An amperometric glucose biosensor has been developed using viologen derivatives as electron mediator of glucose oxidase (GOD) at Au electrode. Highly stable self assembled monolayer (SAM) of thiol-based viologen is immobilized onto the Au electrode followed byGOD is immobilized onto the viologen modified electrode. This biosensor response to glucose was evaluated amperometrically in the potential of -300 mV. Upon immobilization of glucose oxidase onto the viologen modified-electrode, the biosensor showed rapid response towards glucose. Experimental conditions influencing the biosensor performance such as, pH, potential were optimized and assessed. This biosensor offered an excellent electrochemical response for glucose concentration below ${\mu}mol$ level with high sensitivity and selectivity and short response time. The levels of the RSD's (< 5 %) for the entire analyses reflected the highly reproducible sensor performance. Using the optimized a linear relationship between current and glucose concentration was obtained up to $4.5{\times}10^{-4}$ M. In addition, this biosensor showed well reproducibility and stability.

• Molecules and Cells
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• 제40권2호
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• pp.143-150
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• 2017

Homologous recombination (HR) is necessary for maintenance of genomic integrity and prevention of various mutations in tumor suppressor genes and proto-oncogenes. Rad51 and Rad54 are key HR factors that cope with replication stress and DNA breaks in eukaryotes. Rad51 binds to single-stranded DNA (ssDNA) to form the presynaptic filament that promotes a homology search and DNA strand exchange, and Rad54 stimulates the strand-pairing function of Rad51. Here, we studied the molecular dynamics of Rad51 and Rad54 during the cell cycle of HeLa cells. These cells constitutively express Rad51 and Rad54 throughout the entire cell cycle, and the formation of foci immediately increased in response to various types of DNA damage and replication stress, except for caffeine, which suppressed the Rad51-dependent HR pathway. Depletion of Rad51 caused severe defects in response to postreplicative stress. Accordingly, HeLa cells were arrested at the G2-M transition although a small amount of Rad51 was steadily maintained in HeLa cells. Our results suggest that cell cycle progression and proliferation of HeLa cells can be tightly controlled by the abundance of HR proteins, which are essential for the rapid response to postreplicative stress and DNA damage stress.

• 융합보안논문지
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• 제19권1호
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• pp.87-95
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• 2019

점차 고도화되는 사이버 공격에 의한 많은 침해사고로 피해가 증가하고 있다. 많은 기관 및 기업체에서는 사고 탐지를 위한 인프라만에 많은 자원을 투자하기에 초기대응에 미흡하다. 침해사고의 초기대응은 공격의 유입경로 파악이 우선이며, 이루어지고 있는 많은 사이버 공격은 소프트웨어 취약점을 대상으로 하고 있다. 따라서, 소프트웨어 취약점을 대상으로 윈도우 시스템의 아티팩트를 분석하고, 분석한 데이터를 분류하면 신속한 초기대응에 활용할 수 있다. 그러므로 소프트웨어 별 공격 유입 시 남는 아티팩트를 분류하여 침해사고 분석 시에 활용할 수 있는 아티팩트 그룹핑을 제시한다.

• Design & Manufacturing
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• 제8권1호
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• pp.31-34
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• 2014

The Injection molding is used more than 70% of total production in plastic products. The injection molding process has 4 processes such as filling, packing, cooling and ejecting. It spends most of times in the cooling process. Therefore, it is important to control the mold temperature in producing plastic products. The cooling system and time affect the product's quality and productivity. Especially, cooling time has about 60% of total injection cycle time. Therefore, we can improve a productivity by shortening cooling time. In this study, the rapid cooling system was developed and performed a efficiency test. This system could refrigerate coolant to $1^{\circ}C$ and had to need 10 minutes for normal operating. However, if response time of temperature controller and sensor will be increased, the performance of this system will increase.